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题目:: Gene expression profiling of hepatocarcinogenesis initiation in Fischer-344 rats
ID:
状态:: 发布时间June 30, 2009 , 更新时间 May 3, 2014 , 提交时间 July 7, 2008,
物种:: Rattus norvegicus
摘要:: Diethylnitrosamine is used as initiator carcinogen in the modiffied resistan model but is not known its effect on gene expression profile on this stage. In other way, CAPE is compound with anticarcinogenic propertie when is administered 12 h before DEN and with the aim to characterize its effect on gene expression profile when is administered alone and in combination with diethylnitrosamine, these analysis were made. Male Fischer-344 rats were we used 4 animal per each treatment and all treatments are compared with not treated rats. Were identified groups of genes related with Carcinogens metabolism, oxidative stress and cell regulation with important differences between treatments. RT-PCR, enzyme activities, wester blots, metabolism assays were performed to validate these results.
实验种类:: transcription profiling by array
样本量:: 24
实验设计:
: 无设计数据
数据号:: E-GEOD-12030, GSE12030
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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