| GeneLibs

题目:: FAIRE-chip in MCF7 and LNCaP
ID:
状态:: 发布时间May 14, 2010 , 更新时间 March 27, 2012 , 提交时间 May 27, 2008,
物种:: Homo sapiens
摘要:: The compaction degree of chromatin is intimately related to its functionality and active cis-regulatory elements typically exist within open chromatin regions depleted in nucleosomes (Heintzman et al. 2007; Boyle et al. 2008). These domains can be identified using Formaldehyde-Assisted Isolation of Regulatory Elements (FAIRE) that allows for enrichment of nucleosome-depleted genomic regions when cross-linked chromatin is subjected to phenol-chloroform extraction (Nagy et al. 2003; Hogan et al. 2006) Here, chromatin structure was analyzed in MCF7 and LNCaP cells using Formaldehyde-Assisted Isolation of Regulatory Elements (FAIRE) (Nagy et al. 2003; Hogan et al. 2006) Keywords: FAIRE-chip MCF7 and LNCaP cells were grown in full media, cross-linked and processed as in (Nagy et al. 2003; Hogan et al. 2006). DNA obtained by FAIRE was hybridized to Human Affymetrix tiled array F. Triplicates of FAIRE and input DNA are provided (4 inputs for MCF7 cells).
实验种类:: ChIP-chip by tiling array
样本量:: 13
实验设计:
: 无设计数据
数据号:: E-GEOD-11579, GSE11579
数据状态:: 无法自动分析，您可以尝试手动分析数据。

实验库数据相关信息