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题目:: Transcription profiling of rat neuronal progenitor cells after corticosterone treatment
ID:
状态:: 发布时间April 4, 2009 , 更新时间 May 2, 2014 , 提交时间 May 16, 2008,
物种:: Rattus norvegicus
摘要:: Exposure to excessive glucocorticoids, which are major mediators of the stress reaction, is detrimental to brain development related to an increased risk of psychiatric disorders. However, the molecular mechanism underlying the effect of excessive glucocorticoids on the developing brain remains largely unclear. To clarify the mechanism, we examined the effects of glucocorticoids on cultured neuronal progenitor cells (NPCs) from cerebral cortices from rat embryo. We performed comparative analysis using gene expression profiling of corticosterone- or vehicle-treated NPCs. Results provide insight into the effects of glucocorticoids in regulating genetic programs important for controlling NPCs’ properties. Experiment Overall Design: Three couples of RNA samples from corticosterone- or vehicle-treated neuronal progenitor cells were analyzed.
实验种类:: transcription profiling by array
样本量:: 6
实验设计:
: 无设计数据
数据号:: E-GEOD-11478, GSE11478
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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