Transcription profiling of mouse fast and slow invading C6 glial cells
ID:
状态:
发布时间Oct. 27, 2007
, 更新时间 June 10, 2011
, 提交时间 March 23, 2004,
物种:
Rattus norvegicus
摘要:
Identification of genes mediating glioma invasion promotes the understanding of glia motility and might result in biologically based therapeutic approaches. To evaluate migration mechanisms operating in vitro versus in vivo, we used C6 rat glioma cells for selecting highly migratory cells in a monolayer migration assay (C6) as well as in brains of nude mice (C6SPGFP), and analyzed in each paradigm the expression profiles of these fast" cells versus those of the original "slow" cells.