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题目:: Important role for secretoglobin(SCGB)3A2 in lung development
ID:
状态:: 发布时间Dec. 25, 2009 , 更新时间 May 2, 2014 , 提交时间 April 20, 2008,
物种:: Mus musculus
摘要:: Secretoglobin (SCGB) 3A2 was originally identified as a downstream target in lung for the homeodomain transcription factor NKX2-1, whose null mutation resulted in severely hypoplastic lungs. A very low level of SCGB3A2 is expressed in lungs at embryonic day (E) 11.5 during mouse development, which markedly increases by E16.5, the time when lung undergoes dramatic morphological changes. These results suggest that SCGB3A2 may be involved in lung development. We used microarray to determine whether SCGB3A2 plays a role in lung development. Keywords: Response to SCGB3A2 DNA microarray was performed using RNAs isolated from 4 day-organ cultured Nkx2-1-null lungs with and without SCGB3A2 treatment.
实验种类:: transcription profiling by array
样本量:: 8
实验设计:
: 无设计数据
数据号:: E-GEOD-11226, GSE11226
数据状态:: 无法自动分析，您可以尝试手动分析数据。

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