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This gene encodes a member of the transmembrane 9 superfamily. The encoded 76 kDa protein localizes to early endosomes in human cells. The encoded protein possesses a conserved and highly hydrophobic C-terminal domain which contains nine transmembrane domains. The protein may play a role in small molecule transport or act as an ion channel. A pseudogene associated with this gene is located on the X chromosome. [provided by RefSeq, Oct 2012]
[中文简述(自动翻译):]  该基因编码跨膜9超家族的成员。所编码的76 kDa蛋白定位于在人类细胞早期内涵体。所编码的蛋白质具有该包含九个跨膜结构域的保守和高度疏水C-末端结构域。该蛋白可能在小分子运输或行为作用以起离子通道。与这种基因相关的假基因位于X染色体上。 [由RefSeq的,2012年10月提供]
TM9SF2基因(以及对应的蛋白质)的细胞分布位置:
TM9SF2基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
IGA Glomerulonephritis | 0.12 | 1 | 0 | CTD_human |
Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
Malignant neoplasm of temporal lobe | 0.002367032 | 1 | 1 | GAD |
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