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This gene encodes a member of the SLC26 gene family of anion transporters. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. The expression of this gene appears to be restricted to spermatocytes. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2010]
[中文简述(自动翻译):]  该基因编码的SLC26基因家族阴离子转运的成员。家庭成员非常保守的基因结构和蛋白质长度尚未有明显不同的组织表达模式。该基因的表达似乎仅限于精母细胞。编码不同同种型的可变剪接转录物变体已有描述。 [由RefSeq的,2010年7月提供]
SLC26A8基因(以及对应的蛋白质)的细胞分布位置:
SLC26A8基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Azoospermia, Nonobstructive | 0.24 | 1 | 3 | CLINVAR_UNIPROT |
Schizophrenia | 0.12 | 1 | 0 | CTD_human |
Cardiovascular Diseases | 0.002367032 | 1 | 0 | GAD |
Brain Ischemia | 0.002367032 | 1 | 0 | GAD |
Coronary heart disease | 0.002367032 | 1 | 0 | GAD |
Kidney Failure, Chronic | 0.002367032 | 1 | 0 | GAD |
Cerebrovascular accident | 0.002367032 | 1 | 0 | GAD |
Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
HIV Infections | 0.002171535 | 8 | 0 | BeFree |
Malignant neoplasm of urinary bladder | 0.000542884 | 2 | 0 | BeFree |
Carcinoma of bladder | 0.000542884 | 2 | 0 | BeFree |
Bladder Neoplasm | 0.000271442 | 1 | 0 | BeFree |
Drug habituation | 0.000271442 | 1 | 0 | BeFree |
Male infertility | 0.000271442 | 1 | 0 | BeFree |
Lymphoma, Follicular | 0.000271442 | 1 | 0 | BeFree |
nervous system disorder | 0.000271442 | 1 | 0 | BeFree |
Seizures | 0.000271442 | 1 | 0 | BeFree |
Hereditary spherocytosis | 0.000271442 | 1 | 0 | BeFree |
Cervix carcinoma | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of prostate | 0.000271442 | 1 | 0 | BeFree |
Primary spermatogenic failure | 0.000271442 | 1 | 0 | BeFree |
Prostate carcinoma | 0.000271442 | 1 | 0 | BeFree |
SPHEROCYTOSIS, TYPE 1 (disorder) | 0.000271442 | 1 | 0 | BeFree |
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