IDH1(isocitrate dehydrogenase 1 (NADP+), soluble)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

2q34
基因染色体位置图

基因简述

基因简述

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013]

[中文简述(自动翻译):]  异柠檬酸脱氢酶催化异柠檬酸的氧化脱羧到2-酮戊二酸。这些酶属于两个不同的亚类，其中一个利用NAD（+）用作电子受体和其它NADP（+）。五异柠檬酸脱氢酶已经报道：三位NAD（+） - 依赖的异柠檬酸脱氢酶，其定位于线粒体基质，和两个NADP（+） - 依赖的异柠檬酸脱氢酶，其中之一就是线粒体和其他主要胞质。每个NADP（+） - 依赖性同功酶是同型二聚体。蛋白质ENCOD由该基因编在NADP（+） - 依赖的异柠檬酸在细胞质和过氧化物酶体中发现的脱氢酶。它包含的PTS-1过氧化物酶体靶向信号序列。在过氧化物酶这种酶的存在下，在消耗2-酮戊二酸的过氧化物酶反应表明角色的NADPH为intraperoxisomal减少，如2的转换，4-二烯酰基辅酶A到3-烯酰基辅酶A中，再生以及，即植烷酸的α羟基化。细胞质酶供应细胞质NADPH生产显著的作用。已发现此基因编码相同蛋白质可变剪接转录物变体。 [由RefSeq的，2013年9月提供]

OMIM数据库中对IDH1基因的介绍     Wikipedia数据库中对IDH1基因的介绍

基因序列

基因序列

IDH1基因的碱基序列：[NCBI]

基因突变

基因突变

IDH1基因的碱基突变：           显示全部snp
rs1023751       rs1446325       rs10194538       rs10207062       rs12478635       rs12621845       rs12694100       rs28384385       rs55919809       rs73070962       rs73983721       rs73983722       rs74700116       rs75991859       rs76307533       rs76395405       rs76421084       rs76508937       rs78784941       rs79047515       rs79062167       rs112631436       rs113159769       rs113358510       rs114158190       rs114540875       rs114696703       rs114793204       rs115223287       rs116289908       rs116374598       rs139262293       rs140708194       rs140814000       rs143826903       rs144856461       rs147924092      
rs148973647       rs149743342       rs181400216       rs183195427       rs183309933       rs183459801       rs185760535       rs186397451       rs187051367       rs187571325       rs188706334       rs189891775       rs190399516       rs191563468       rs192544772       rs369485172       rs370043668       rs374074633       rs377011618       rs528108746       rs529051699       rs530262875       rs530522219       rs531780640       rs532572742       rs532778608       rs533006274       rs533541697       rs534308390       rs537288532       rs537765795       rs538360925       rs538695310       rs539330725       rs540346162       rs542829007       rs543687633       rs543849963       rs544927674       rs545303494       rs545361237       rs546072850       rs547002679       rs548601252       rs548860575       rs549260808       rs550282579       rs550577948       rs551348194       rs553872499       rs553939831       rs554145137       rs554417269       rs555136341       rs557710688       rs558402258       rs558455121       rs558817059       rs559431265       rs560626062       rs560755001       rs562222486       rs563367302       rs563483962       rs565557111       rs566680252       rs567534950       rs568419270       rs568481115       rs569556824       rs570839477       rs572908835       rs573041354       rs573849306       rs573910992       rs574977217       rs575177832       rs576674276       rs3778       rs966730       rs1044416       rs1061944       rs1437410       rs1446322       rs1446323       rs1446324       rs1982335       rs3769521       rs3769522       rs3841868       rs3928183       rs5023936       rs6435435       rs6725277       rs6730955       rs7565247       rs7609093       rs9646837       rs9646838       rs10170549       rs10202116       rs11370730       rs11433971       rs11554137       rs11554138       rs11685614       rs11888463       rs11900211       rs12612631       rs13395413       rs16840781       rs16840789       rs16840791       rs16840793       rs16840794       rs16840798       rs16840801       rs16840803       rs16841606       rs17652540       rs28522161       rs28658028       rs34218846       rs34599179       rs35384132       rs35940089       rs57383668       rs58211203       rs59684347       rs62193614       rs62193615       rs62193616       rs66547921       rs67202912       rs67693848       rs71036995       rs71412484       rs71412485       rs71418671       rs72976889       rs72989215       rs72989217       rs73070950       rs73070954       rs73070958       rs73983718       rs73983719       rs73983720       rs73983723       rs75255537       rs75275293       rs75634689       rs75919189       rs76423964       rs76993564       rs77019880       rs77262173       rs77407764       rs77449519       rs77969688       rs78030598       rs78539882       rs78562918       rs78814139       rs79191318       rs79246690       rs79347029       rs79385589       rs80264001       rs111233394       rs111239276       rs111240462       rs111539830       rs111768362       rs111791823       rs111834611       rs112028914       rs112185121       rs112594278       rs112625205       rs112722672       rs112722785       rs112738668       rs113049026       rs113102228       rs113158529       rs113185513       rs113340992       rs113507946       rs113576528       rs113593983       rs113664044       rs113732076       rs113995440       rs114000671       rs114459199       rs114543007       rs114728649       rs114939378       rs115216870       rs115251213       rs115256246       rs115307013       rs115451211       rs116460523       rs116516330       rs116548235       rs116833301       rs116915757       rs117747365       rs137929585       rs138458978       rs138554133       rs138680966       rs138762161       rs139018716       rs139287550       rs139308205       rs139404756       rs139925909       rs139986103       rs140439206       rs140594787       rs141118556       rs141133214       rs141226540       rs141630472       rs141671114       rs141699410       rs141777039       rs141895800       rs142357571       rs142508986       rs142549102       rs142572024       rs142801125       rs142883642       rs142923780       rs143440055       rs143503410       rs143763006       rs144021954       rs144082087       rs144223704       rs144283708       rs144573553       rs144593536       rs144680615       rs145324788       rs145701825       rs146240928       rs146273840       rs146540315       rs146669751       rs146908656       rs147147694       rs147684527       rs148016456       rs148160119       rs148190775       rs148355810       rs148459874       rs148462855       rs148491376       rs148542200       rs148981307       rs149205273       rs149246134       rs149418650       rs149447798       rs149783383       rs149941485       rs150466080       rs150582330       rs150747919       rs150906753       rs151022153       rs180928167       rs180994140       rs181248679       rs181311792       rs181955506       rs182206511       rs182374552       rs182456552       rs182465655       rs182693596       rs183121276       rs183239802       rs183598176       rs183880172       rs183995491       rs184072273       rs184147380       rs184216056       rs184577889       rs185079000       rs185188955       rs185564694       rs185916564       rs186163757       rs186497092       rs186787509       rs186944298       rs187244118       rs187350953       rs187374187       rs187882667       rs187924894       rs188015621       rs188464414       rs188499120       rs188887992       rs189367779       rs189408695       rs189476895       rs190258672       rs190827021       rs190837462       rs190943538       rs190945878       rs191482824       rs191603580       rs191762013       rs191818670       rs191864560       rs192251665       rs192514135       rs192934083       rs192948900       rs193249271       rs193274457       rs199743726       rs199793362       rs200122564       rs200227531       rs200305649       rs200591678       rs200718328       rs200866943       rs200918475       rs201016875       rs201164623       rs201258988       rs201267625       rs201394139       rs201477228       rs201504723       rs201712733       rs201723505       rs201787135       rs201790850       rs201822210       rs367706953       rs367767216       rs367779209       rs367959618       rs368194433       rs368411486       rs368431420       rs368642313       rs368904931       rs369039979       rs369048275       rs369234651       rs369424896       rs369626546       rs369672159       rs369898908       rs370095740       rs370342586       rs370896578       rs370928521       rs371567806       rs371837057       rs371930274       rs372525357       rs372698870       rs372711897       rs372748968       rs373048968       rs373514235       rs373716006       rs374340555       rs374454878       rs374474539       rs374900600       rs374907791       rs375159545       rs375358749       rs375423243       rs375658806       rs375976483       rs376394192       rs376666493       rs377075054       rs377475055       rs377538429       rs527515332       rs527906290       rs527986652       rs528249056       rs528255792       rs528555093       rs528928825       rs529066592       rs529081836       rs529117793       rs529132113       rs529242500       rs529351698       rs529425534       rs529647587       rs530131828       rs530450674       rs530490960       rs530619587       rs530896902       rs530911671       rs531431831       rs531450691       rs531970634       rs532066985       rs532633057       rs532947500       rs533101765       rs533316146       rs533401517       rs533578934       rs533703745       rs533711178       rs533831794       rs533846555       rs534154582       rs534213637       rs534430448       rs535106527       rs535464050       rs535512347       rs535551892       rs535732811       rs536481822       rs536614679       rs536671284       rs536750332       rs536880332       rs537630586       rs537631493       rs537689371       rs537696492       rs537894067       rs538164572       rs538405035       rs538496757       rs538535563       rs538822402       rs539198365       rs539282861       rs539879110       rs539924035       rs540137743       rs540372746       rs540596735       rs540991868       rs541128868       rs541624778       rs541722980       rs541913058       rs542596725       rs542653633       rs542820535       rs542829254       rs542890615       rs543637142       rs544049717       rs544075193       rs544183861       rs544261201       rs544363956       rs544397853       rs544639859       rs544978011       rs545271698       rs545308124       rs545436546       rs546239259       rs546314404       rs546314478       rs546329654       rs547266441       rs547698484       rs548058734       rs548115867       rs548541375       rs548881825       rs548998976       rs549200589       rs549470603       rs549901317       rs549992412       rs550007005       rs550142298       rs550163700       rs550533920       rs550593396       rs551081699       rs551103032       rs551263420       rs551720716       rs552404188       rs552624989       rs552730264       rs552953330       rs553278475       rs554205606       rs554273142       rs554301628       rs554334473       rs554341525       rs554480433       rs554912996       rs554979559       rs555001412       rs555195547       rs555529646       rs555648474       rs555882127       rs555920144       rs556339788       rs556437814       rs557263619       rs557788219       rs557802806       rs557887986       rs558073319       rs558674711       rs558721662       rs559181479       rs559332297       rs559400240       rs559459869       rs559596551       rs559724446       rs559726397       rs559769624       rs559796394       rs559985911       rs560029371       rs560262780       rs560543343       rs560551624       rs560813101       rs561052706       rs561114283       rs561210868       rs561460472       rs561668293       rs561722525       rs561739952       rs562416222       rs562495660       rs563106341       rs563354238       rs563489056       rs564134776       rs564140008       rs564647270       rs564801526       rs564842461       rs564930424       rs565065820       rs565194894       rs565206043       rs565348636       rs565411018       rs565626541       rs565699710       rs565882700       rs566023900       rs566072712       rs566087869       rs566212339       rs566274421       rs566729272       rs567061668       rs567401796       rs567868300       rs567931337       rs568257235       rs568481376       rs568660276       rs568720597       rs569424950       rs569519336       rs569682700       rs570033683       rs570089018       rs570317661       rs570327830       rs570863331       rs570901027       rs571127881       rs571368383       rs571438247       rs571572936       rs571771088       rs572027563       rs572153143       rs573150379       rs573985103       rs574200282       rs574247830       rs574734763       rs574978973       rs575296267       rs575372922       rs575483212       rs576011003       rs576632204       rs576724687       rs576750769       rs576795270       rs577252447       rs577642373       rs578186708       rs587778401       rs587778402       rs745329811       rs745504857       rs745513295       rs746329143       rs746483551       rs746615557       rs746931121       rs747198657       rs747226100       rs747384833       rs747419787       rs747514271       rs747728869       rs747809723       rs747900297       rs747951792       rs748131660       rs748255418       rs748255496       rs748380012       rs748499158       rs748768472       rs748795422       rs748821411       rs749095391       rs749391619       rs749727667       rs750002102       rs750036692       rs750167144       rs750251172       rs750309673       rs750362869       rs750457328       rs750612823       rs751010715       rs751147148       rs751189315       rs751364381       rs751525590       rs751591193       rs751649071       rs751878699       rs752078425       rs752130008       rs752187592       rs752314107       rs752595957       rs752813398       rs753237040       rs753361096       rs753580953       rs753981193       rs754042652       rs754088842       rs754290687       rs754316078       rs754957038       rs755237893       rs755385980       rs755404974       rs755612585       rs756057424       rs756272474       rs756393190       rs756395116       rs756495066       rs756511163       rs756798008       rs756940135       rs756942230       rs757031960       rs757389021       rs757444051       rs757639083       rs758141442       rs758215808       rs758284930       rs758405875       rs758524291       rs758597026       rs758622511       rs758956872       rs759011836       rs759217866       rs759303223       rs759315203       rs759352410       rs759413310       rs759537076       rs759561216       rs760003909       rs760014854       rs760239354       rs760287259       rs760579117       rs760963029       rs761315922       rs761344510       rs761440376       rs761830115       rs762089749       rs762126667       rs762143982       rs762178005       rs762479277       rs762792137       rs762820641       rs762867621       rs762954264       rs763043045       rs763231487       rs763282939       rs763413042       rs763478345       rs763504710       rs763562621       rs763685036       rs763941915       rs764279541       rs764338499       rs764425733       rs764523200       rs764563398       rs764654685       rs764710065       rs765037248       rs765179388       rs765230533       rs765282142       rs765456997       rs765662006       rs765848107       rs765911880       rs766246232       rs766372640       rs766541984       rs766547920       rs766985383       rs767109945       rs767185144       rs767630531       rs767633282       rs767649425       rs767852664       rs767925620       rs768250871       rs768304856       rs768477067       rs768513536       rs768596300       rs768836031       rs768960539       rs769119726       rs769274104       rs769450782       rs769575550       rs769739538       rs770226824       rs770397598       rs770499329       rs770547080       rs770821204       rs771247780       rs771358905       rs771481912       rs771578786       rs771692756       rs771701369       rs771918726       rs771971686       rs772297042       rs772304188       rs772356149       rs772485166       rs772594297       rs772662700       rs772900658       rs772975591       rs773076468       rs773167891       rs773327968       rs773611901       rs773617210       rs773792199       rs774171850       rs774294185       rs774646429       rs774721532       rs775133036       rs775186249       rs775390663       rs775517144       rs775595570       rs775623666       rs775678660       rs775893896       rs775936968       rs776041038       rs776372851       rs776449775       rs776463533       rs776513405       rs776630219       rs777025307       rs777129475       rs777151708       rs777403667       rs777431979       rs777599273       rs777761062       rs778083499       rs778168552       rs778537293       rs778615461       rs779126307       rs779481497       rs779983545       rs780091173       rs780146398       rs780519217       rs780642190       rs780738017       rs781009655       rs781132701       rs781222279       rs781228441       rs781365220       rs781398075       rs781531255       rs781533021       rs781584145      

基因表达

基因表达

IDH1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
AACTTTGAAGAAGGTGGTGG
58
AGCCATTTGGAAGGAACTG
58
TTGTGAGTCTGAGCTTGTG
58
GAATGTAGTTTATCGCCTGC
57
AACTTTGAAGAAGGTGGTGG
58
AGCCATTTGGAAGGAACTG
58
GGATCTACATAGCTATGATTTAGGC
59
TATAGCTTCTGCAGCATCCT
59
CTATTGAGACAATTGAGGCTGG
59
TCAGAACGTTGCACATTGG
59
CAAGGAGATGAAATGACACGA
59
GCCTAAATCATAGCTATGTAGATCC
59
TATTGAGACAATTGAGGCTGG
58
TCAGAACGTTGCACATTGG
59
GTTGTGAGTCTGAGCTTGTG
59
AATGTAGTTTATCGCCTGCC
59
TGTGAGTCTGAGCTTGTGAG
60
TGAATGTAGTTTATCGCCTGC
59
TTGTGAGTCTGAGCTTGTG
58
GAATGTAGTTTATCGCCTGC
57

转录因子

转录因子

      尚未收录相关数据

基因本体信息

IDH1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

IDH1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0004450
C9J4N6(UniProtKB)
IEA
GO:0006102
C9J4N6(UniProtKB)
IEA
GO:0055114
C9J4N6(UniProtKB)
IEA
GO:0004450
C9JJE5(UniProtKB)
IEA
GO:0006102
C9JJE5(UniProtKB)
IEA
GO:0055114
C9JJE5(UniProtKB)
IEA
GO:0004450
C9JLU6(UniProtKB)
IEA
GO:0006102
C9JLU6(UniProtKB)
IEA
GO:0055114
C9JLU6(UniProtKB)
IEA
GO:0000287
O75874(UniProtKB)
IDA
GO:0004450
O75874(UniProtKB)
IDA
GO:0004450
O75874(UniProtKB)
EXP
GO:0004450
O75874(UniProtKB)
EXP
GO:0004450
O75874(UniProtKB)
IDA
GO:0004450
O75874(UniProtKB)
IDA
GO:0005102
O75874(UniProtKB)
IPI
GO:0005737
O75874(UniProtKB)
IDA
GO:0005739
O75874(UniProtKB)
IEA
GO:0005777
O75874(UniProtKB)
IDA
GO:0005782
O75874(UniProtKB)
TAS
GO:0005829
O75874(UniProtKB)
IDA
GO:0005829
O75874(UniProtKB)
TAS
GO:0005829
O75874(UniProtKB)
TAS
GO:0006097
O75874(UniProtKB)
IEA
GO:0006099
O75874(UniProtKB)
IEA
GO:0006102
O75874(UniProtKB)
IDA
GO:0006102
O75874(UniProtKB)
IDA
GO:0006102
O75874(UniProtKB)
IDA
GO:0006103
O75874(UniProtKB)
IDA
GO:0006103
O75874(UniProtKB)
TAS
GO:0006740
O75874(UniProtKB)
TAS
GO:0006749
O75874(UniProtKB)
IEA
GO:0006979
O75874(UniProtKB)
IEA
GO:0008585
O75874(UniProtKB)
IEA
GO:0042803
O75874(UniProtKB)
IPI
GO:0048545
O75874(UniProtKB)
IEA
GO:0050661
O75874(UniProtKB)
IEA
GO:0051287
O75874(UniProtKB)
IEA
GO:0051990
O75874(UniProtKB)
EXP
GO:0060696
O75874(UniProtKB)
IEA
GO:0070062
O75874(UniProtKB)
IDA
GO:0070062
O75874(UniProtKB)
IDA
GO:0070062
O75874(UniProtKB)
IDA
GO:0071071
O75874(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控IDH1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Enchondromatosis 0.240814326 4 0 BeFree_CTD_human_ORPHANET
Glioma 0.221550393 298 5 BeFree_CTD_human_GAD_LHGDN
oligodendroglioma 0.138783028 37 3 BeFree_CTD_human_GAD_LHGDN
Cholangiocarcinoma 0.122171535 8 0 BeFree_CTD_human
Maffucci Syndrome 0.121085767 4 1 BeFree_ORPHANET
Precursor Cell Lymphoblastic Leukemia Lymphoma 0.121085767 5 2 BeFree_CTD_human
Hemangioma 0.120542884 2 3 BeFree_CTD_human
gliosarcoma 0.120542884 2 0 BeFree_ORPHANET
Chondroma 0.120542884 3 0 BeFree_CTD_human
Liver carcinoma 0.120542884 3 0 BeFree_CTD_human
Giant Cell Glioblastoma 0.12 0 0 ORPHANET
METAPHYSEAL ENCHONDROMATOSIS WITH D-2-HYDROXYGLUTARIC ACIDURIA 0.12 0 0 ORPHANET
Glioblastoma 0.052842746 133 4 BeFree_GAD_LHGDN
Leukemia, Myelocytic, Acute 0.051205501 86 3 BeFree_GAD
Brain Neoplasms 0.039924495 38 1 BeFree_GAD
Astrocytoma 0.027936107 60 2 BeFree_GAD_LHGDN
Preleukemia 0.010282454 7 0 BeFree_GAD
MYELODYSPLASTIC SYNDROME 0.010282454 7 0 BeFree_GAD
Well Differentiated Oligodendroglioma 0.008957582 33 3 BeFree
Anaplastic astrocytoma 0.006786047 25 1 BeFree
Anaplastic Oligodendroglioma 0.006786047 25 3 BeFree
Carcinogenesis 0.006786047 25 3 BeFree
Blast Phase 0.00554839 3 0 BeFree_GAD
Secondary Glioblastoma 0.005428837 20 1 BeFree
Myeloproliferative disease 0.005276948 4 0 BeFree_GAD
Hematological Disease 0.005005506 2 0 BeFree_GAD
Malignant Glioma 0.004614512 17 2 BeFree
leukemia 0.00434307 16 0 BeFree
Primary Myelofibrosis 0.003724241 5 3 BeFree_GAD
melanoma 0.003724241 5 0 BeFree_GAD
Polycythemia Vera 0.003452799 4 3 BeFree_GAD
Thrombocythemia, Essential 0.003181358 3 2 BeFree_GAD
Low grade glioma 0.002985861 11 1 BeFree
HIV Infections 0.002909916 2 0 BeFree_GAD
Neoplasm Metastasis 0.002909916 2 0 BeFree_GAD
Chondrosarcoma 0.002714419 10 0 BeFree
Lymphoma, Non-Hodgkin 0.002638474 2 1 BeFree_GAD
Supratentorial Neoplasms 0.002638474 2 0 BeFree_GAD
Thyroid Neoplasm 0.002638474 1 0 BeFree_GAD
Neuroectodermal Tumor, Primitive 0.002638474 2 0 BeFree_GAD
Glioblastoma Multiforme 0.002442977 9 1 BeFree
Carcinoma, Papillary 0.002367032 1 0 GAD
Chromosome Aberrations 0.002367032 1 0 GAD
Leukemia, Myelomonocytic, Chronic 0.002367032 1 0 GAD
Lung Neoplasms 0.002367032 1 0 GAD
Monosomy 0.002367032 1 0 GAD
Nervous System Neoplasms 0.002367032 1 0 GAD
Pancreatic Neoplasm 0.002367032 1 0 GAD
Skin Neoplasms 0.002367032 1 0 GAD
Medullary carcinoma 0.002367032 1 0 GAD
Oxyphilic Adenoma 0.002367032 1 0 GAD
Diffuse Astrocytoma 0.002171535 8 0 BeFree
Pilocytic Astrocytoma 0.002171535 8 2 BeFree
Primary Glioblastoma 0.002171535 8 0 BeFree
Seizures 0.001900093 7 1 BeFree
Hematologic Neoplasms 0.001900093 7 0 BeFree
Intrahepatic Cholangiocarcinoma 0.001628651 6 0 BeFree
Adult Acute Myeloblastic Leukemia 0.001357209 5 1 BeFree
Solid tumour 0.001357209 5 0 BeFree
Thyroid carcinoma 0.001357209 5 0 BeFree
Cytogenetically normal acute myeloid leukemia 0.001357209 5 1 BeFree
Acute lymphocytic leukemia 0.001085767 4 2 BeFree
Myeloid Leukemia 0.001085767 4 0 BeFree
Malignant neoplasm of brain 0.001085767 4 1 BeFree
Mixed Oligodendroglioma-Astrocytoma 0.001085767 4 1 BeFree
Gliomatosis cerebri 0.001085767 4 1 BeFree
Leukemogenesis 0.001085767 4 0 BeFree
Brain Tumor, Primary 0.001085767 4 0 BeFree
Malignant neoplasm of thyroid 0.000814326 3 0 BeFree
Colorectal Carcinoma 0.000814326 3 0 BeFree
Lymphoma 0.000814326 3 0 BeFree
Central Nervous System Neoplasms 0.000814326 3 0 BeFree
Tumor Progression 0.000814326 3 0 BeFree
pediatric acute myeloblastic leukemia 0.000814326 3 0 BeFree
Neoplasm, Residual 0.000814326 3 0 BeFree
Anaplastic Oligoastrocytoma 0.000814326 3 1 BeFree
Dedifferentiated chondrosarcoma 0.000814326 3 0 BeFree
Astrocytoma, low grade 0.000814326 3 0 BeFree
Oligodendroglial Neoplasm 0.000814326 3 0 BeFree
Conventional Chondrosarcoma 0.000814326 3 0 BeFree
Colorectal Cancer 0.000814326 3 0 BeFree
Enchondroma 0.000814326 3 0 BeFree
Adenocarcinoma 0.000542884 2 0 BeFree
Malignant neoplasm of breast 0.000542884 2 1 BeFree
Non-Small Cell Lung Carcinoma 0.000542884 2 0 BeFree
Ependymoma 0.000542884 2 1 BeFree
Angioimmunoblastic Lymphadenopathy 0.000542884 2 0 BeFree
Myeloid Leukemia, Chronic 0.000542884 2 2 BeFree
Acute Promyelocytic Leukemia 0.000542884 2 0 BeFree
Acute Myeloid Leukemia, M1 0.000542884 2 0 BeFree
Osteosarcoma 0.000542884 2 0 BeFree
Pheochromocytoma 0.000542884 2 0 BeFree
Acute leukemia 0.000542884 2 0 BeFree
Follicular thyroid carcinoma 0.000542884 2 0 BeFree
Ganglioglioma 0.000542884 2 0 BeFree
high-grade childhood cerebral astrocytoma 0.000542884 2 1 BeFree
Vascular Neoplasms 0.000542884 2 1 BeFree
Malignant neoplasm of prostate 0.000542884 2 0 BeFree
Chondrogenic Neoplasm 0.000542884 2 0 BeFree
Breast Carcinoma 0.000542884 2 1 BeFree
Biliary Tract Cancer 0.000542884 2 0 BeFree
Rash and Dermatitis Adverse Event Associated with Chemoradiation 0.000542884 2 1 BeFree
Non-Neoplastic Disorder 0.000542884 2 0 BeFree
Congenital Abnormality 0.000271442 1 1 BeFree
Aplastic Anemia 0.000271442 1 0 BeFree
Mental disorders 0.000271442 1 0 BeFree
Bone neoplasms 0.000271442 1 0 BeFree
Malignant tumor of colon 0.000271442 1 0 BeFree
Congenital chromosomal disease 0.000271442 1 0 BeFree
Ulcerative Colitis 0.000271442 1 0 BeFree
Common Cold 0.000271442 1 0 BeFree
Craniopharyngioma 0.000271442 1 0 BeFree
Epilepsy 0.000271442 1 0 BeFree
Fibrosarcoma 0.000271442 1 1 BeFree
Giant Cell Tumors 0.000271442 1 0 BeFree
Hepatitis 0.000271442 1 0 BeFree
Hepatitis A 0.000271442 1 0 BeFree
Kidney Failure, Acute 0.000271442 1 0 BeFree
Vulvar Lichen Sclerosus 0.000271442 1 0 BeFree
Paroxysmal nocturnal hemoglobinuria 0.000271442 1 0 BeFree
Metabolic Diseases 0.000271442 1 0 BeFree
Paraganglioma 0.000271442 1 0 BeFree
Precancerous Conditions 0.000271442 1 0 BeFree
Soft Tissue Neoplasms 0.000271442 1 0 BeFree
Li-Fraumeni Syndrome 0.000271442 1 1 BeFree
Neoplasms, Neuroepithelial 0.000271442 1 1 BeFree
Lesion of brain 0.000271442 1 0 BeFree
Papillary thyroid carcinoma 0.000271442 1 0 BeFree
Telangiectatic osteosarcoma 0.000271442 1 0 BeFree
mixed gliomas 0.000271442 1 0 BeFree
Acute respiratory failure 0.000271442 1 0 BeFree
Petit mal status 0.000271442 1 0 BeFree
Liver and Intrahepatic Biliary Tract Carcinoma 0.000271442 1 0 BeFree
Chondroblastic osteosarcoma 0.000271442 1 0 BeFree
secondary acute myeloid leukemia 0.000271442 1 0 BeFree
Malignant neoplasm of liver 0.000271442 1 0 BeFree
Pilocytic astrocytoma of cerebellum 0.000271442 1 0 BeFree
Nijmegen Breakage Syndrome 0.000271442 1 0 BeFree
Chromosome 8, trisomy 0.000271442 1 0 BeFree
Recurrent tumor 0.000271442 1 0 BeFree
Tumor Initiation 0.000271442 1 0 BeFree
Prostate carcinoma 0.000271442 1 0 BeFree
Glioma of brainstem 0.000271442 1 0 BeFree
Progressive Neoplastic Disease 0.000271442 1 0 BeFree
Colon Carcinoma 0.000271442 1 0 BeFree
Stomach Carcinoma 0.000271442 1 2 BeFree
Germ Cell Cancer 0.000271442 1 0 BeFree
Chromosome 1, monosomy 1p 0.000271442 1 0 BeFree
Chromosome 8, monosomy 8p 0.000271442 1 0 BeFree
Chromosome 8, trisomy 8p 0.000271442 1 0 BeFree
Breast adenocarcinoma 0.000271442 1 0 BeFree
Intestinal adenocarcinoma 0.000271442 1 0 BeFree
Chronic myeloproliferative disorder 0.000271442 1 0 BeFree
Single tumor 0.000271442 1 1 BeFree
Spindle cell hemangioma 0.000271442 1 0 BeFree
Vascular lesions 0.000271442 1 3 BeFree
Xenograft Model 0.000271442 1 0 BeFree
Neoplasms, Intracranial 0.000271442 1 0 BeFree
Neurocytoma 0.000271442 1 0 BeFree
Grade I Astrocytoma 0.000271442 1 0 BeFree
D-2-hydroxyglutaric aciduria 0.000271442 1 0 BeFree
MULTICYSTIC RENAL DYSPLASIA, BILATERAL 0.000271442 1 0 BeFree
Combined D-2- and L-2-hydroxyglutaric aciduria 0.000271442 1 0 BeFree
Progressive cGVHD 0.000271442 1 0 BeFree
Radiation Damage 0.000271442 1 0 BeFree

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