H19(H19, imprinted maternally expressed transcript (non-protein coding))

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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11p15.5
基因染色体位置图

This gene is located in an imprinted region of chromosome 11 near the insulin-like growth factor 2 (IGF2) gene. This gene is only expressed from the maternally-inherited chromosome, whereas IGF2 is only expressed from the paternally-inherited chromosome. The product of this gene is a long non-coding RNA which functions as a tumor suppressor. Mutations in this gene have been associated with Beckwith-Wiedemann Syndrome and Wilms tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

[中文简述(自动翻译):]  该基因位于胰岛素样生长因子2(IGF2)基因邻近的染色体11的压印区域。该基因只从母系遗传染色体表达,而IGF2仅从父系继承染色体表达。这个基因的产物是一个长的非编码RNA,其功能作为肿瘤抑制基因。该基因突变与威思 - 威德曼综合征和肾母细胞肿瘤发生有关。选择性剪接结果在多个抄本变形。 [由RefSeq的,2015年4月提供]

H19基因的碱基序列:[NCBI]
H19基因的碱基突变:           显示全部snp
rs217727       rs2067051       rs2071094       rs2071095       rs2075744       rs2075745       rs2107425       rs2158394       rs2251312       rs2251375       rs2525881       rs2525882       rs2525883       rs2525884       rs2525885       rs2525886       rs2668850       rs2735469       rs2735969       rs2735970       rs2735971       rs2735972       rs2839698       rs2839701       rs2839702       rs2839703       rs2839704       rs3024270       rs3741216       rs3741219       rs3825028       rs4929983       rs4929984       rs4930098       rs4930101       rs4930103       rs7105554      
rs10840159       rs10840167       rs11042167       rs11042170       rs11542716       rs11542717       rs11542721       rs11542723       rs11542724       rs11564733       rs11564736       rs11564737       rs11564738       rs11564740       rs11564741       rs12417375       rs12577355       rs17658052       rs35617388       rs35678657       rs35787113       rs56125822       rs57889360       rs58473705       rs59937557       rs60746422       rs61383602       rs61520309       rs72556550       rs72556551       rs74668776       rs75195511       rs76162918       rs76989783       rs78033535       rs78276179       rs78510912       rs80194862       rs111265160       rs111787010       rs112005965       rs112056845       rs112404063       rs113013264       rs113046940       rs113390616       rs113480908       rs113539650       rs114045585       rs114212142       rs114679781       rs114841108       rs115007717       rs115367311       rs115696222       rs115855861       rs116273324       rs116309118       rs116705060       rs117240203       rs117916983       rs138136974       rs138379956       rs138584587       rs139724170       rs139771781       rs139832343       rs141293584       rs142115792       rs143289570       rs143711867       rs143896465       rs144472866       rs144539192       rs145181743       rs145330941       rs146238677       rs146358455       rs146867677       rs146878777       rs146988371       rs148433042       rs148619931       rs149202370       rs149245793       rs149310815       rs150757470       rs151056077       rs151275915       rs180722873       rs181297098       rs181755649       rs182096548       rs182722666       rs183352770       rs183521532       rs185111479       rs185559291       rs186902469       rs187156851       rs187194726       rs188008460       rs188300566       rs189671759       rs189922880       rs189959118       rs191362969       rs191489175       rs191649571       rs192465180       rs192699622       rs199912364       rs200288360       rs201713485       rs368205764       rs368244047       rs368703928       rs368877698       rs368911734       rs369312603       rs369409025       rs369668916       rs369695469       rs369872443       rs369974003       rs369977074       rs370146073       rs371245806       rs371378746       rs371414038       rs371698714       rs371736340       rs372233017       rs373019918       rs373277183       rs373445836       rs373536357       rs373659665       rs373838871       rs374736833       rs374905167       rs375009224       rs375162606       rs375233458       rs375452190       rs375462385       rs376099905       rs376206193       rs376249764       rs376463156       rs376650475       rs377382896       rs377448027       rs431825164       rs527493348       rs527737567       rs528051899       rs528172561       rs529061110       rs529217115       rs529671866       rs529675846       rs529797444       rs529987006       rs530211922       rs530471900       rs530628139       rs531028595       rs531109782       rs531113572       rs531579904       rs531877707       rs531933855       rs532157807       rs532294534       rs532384710       rs532552333       rs532579481       rs532617741       rs533417502       rs533558826       rs534170215       rs534219523       rs534531915       rs535534702       rs535819197       rs535835391       rs535889680       rs536028424       rs536453160       rs536503832       rs536837590       rs536873399       rs536974619       rs537184127       rs537432584       rs537900857       rs538109209       rs538661579       rs539832419       rs539874465       rs540502721       rs540798895       rs540816939       rs541060825       rs541098166       rs541113236       rs541384096       rs541887576       rs541911007       rs542221174       rs542451751       rs542504845       rs542572776       rs542838375       rs543139035       rs543551919       rs543568525       rs543862815       rs544222336       rs544552792       rs545189759       rs545220745       rs545283073       rs545284025       rs545454745       rs546419442       rs546520265       rs546751885       rs546879212       rs547035009       rs547054243       rs547522031       rs547690018       rs547916667       rs548066462       rs548101874       rs548453983       rs548604132       rs548803905       rs549175976       rs549390374       rs549460362       rs549875901       rs549892030       rs550049599       rs550180086       rs550852402       rs551245238       rs551634894       rs551876362       rs551906413       rs552984530       rs553207520       rs553494779       rs553979403       rs553988547       rs554392475       rs554581976       rs554699742       rs555155736       rs555389525       rs556040130       rs556090173       rs556171400       rs556388040       rs556475447       rs556512315       rs556527122       rs557412407       rs557449331       rs557449408       rs557699757       rs558112079       rs558377801       rs558471996       rs558506703       rs558606129       rs558642937       rs559121497       rs559210126       rs559608948       rs559932586       rs560561084       rs560663655       rs560889390       rs560967284       rs561212418       rs561446358       rs561457191       rs561694716       rs562005293       rs562040346       rs562623966       rs562823846       rs562902963       rs562965702       rs563387293       rs563850518       rs563865428       rs564032890       rs564626551       rs564943934       rs564965839       rs564999199       rs565243432       rs565540545       rs565633797       rs565799871       rs566059534       rs566718442       rs566875019       rs567011313       rs567248083       rs567678567       rs567946239       rs568497589       rs568539792       rs569244353       rs569406791       rs569506608       rs569884684       rs569929858       rs570278157       rs570622437       rs571229462       rs571576578       rs572136086       rs572243693       rs572306720       rs572342743       rs573450521       rs573548085       rs573923500       rs574186242       rs574749377       rs574750713       rs574986254       rs575037909       rs575501124       rs575848160       rs576046732       rs576050393       rs576164981       rs576630757       rs576812762       rs577190688       rs577933476       rs577968277       rs578029526       rs578086985       rs578128538       rs745379570       rs745433541       rs745434712       rs745666058       rs745718962       rs745757247       rs745800394       rs745810181       rs746127062       rs746288770       rs746488763       rs746563830       rs746571434       rs746624537       rs746650192       rs746761594       rs746982390       rs747090928       rs747141756       rs747143897       rs747328776       rs747365959       rs747425680       rs747526239       rs747556950       rs747646425       rs747732025       rs747750146       rs747954870       rs748026642       rs748113032       rs748253962       rs748345774       rs748370774       rs748421309       rs748692991       rs749086440       rs749141470       rs749195277       rs749371141       rs749526897       rs749561754       rs749827861       rs749928305       rs750034401       rs750086353       rs750088229       rs750333975       rs750437023       rs750799142       rs750869473       rs750983016       rs751125332       rs751232893       rs751282438       rs751309386       rs751574748       rs751635496       rs751741836       rs751797157       rs751901109       rs751962180       rs752324156       rs752398183       rs752418044       rs752770278       rs752868692       rs752873808       rs752921629       rs753076724       rs753094402       rs753206673       rs753314512       rs753545443       rs753679272       rs753732379       rs753785618       rs753822624       rs753836639       rs754008980       rs754039484       rs754196445       rs754304969       rs754326362       rs754360673       rs754381130       rs754451003       rs754554687       rs754582297       rs754858620       rs754878147       rs754985623       rs755022597       rs755043209       rs755147035       rs755168820       rs755331373       rs755363476       rs755537301       rs755554327       rs755674961       rs755785499       rs755930281       rs755990018       rs756160943       rs756212842       rs756332707       rs756490431       rs756608025       rs756720140       rs756781942       rs756839337       rs756867575       rs757028868       rs757261102       rs757298764       rs757493882       rs757656423       rs757711466       rs757761252       rs757959001       rs758204094       rs758433100       rs758599358       rs758627187       rs758648106       rs758915929       rs759021207       rs759134214       rs759289987       rs759392118       rs759552355       rs759566943       rs759634204       rs760146151       rs760222753       rs760426521       rs760447421       rs760612457       rs760664846       rs760719856       rs760834170       rs761030121       rs761106414       rs761282976       rs761454175       rs761558685       rs761659392       rs761736092       rs761837808       rs761964445       rs762015262       rs762150532       rs762274828       rs762390505       rs762498693       rs762591946       rs762699600       rs762704292       rs762905753       rs762931682       rs763137072       rs763141577       rs763249074       rs763322863       rs763401026       rs763704036       rs763768485       rs763810508       rs763985723       rs764420056       rs764450167       rs764847370       rs764873284       rs765080467       rs765095580       rs765306985       rs765414881       rs765432066       rs765467463       rs765481699       rs765523428       rs765824108       rs765995936       rs766168463       rs766430475       rs766456754       rs766683341       rs766840094       rs766988014       rs767117042       rs767138912       rs767145514       rs767194080       rs767247053       rs767528635       rs768128969       rs768229301       rs768229302       rs768282254       rs768388545       rs768494840       rs768575700       rs768791984       rs769073885       rs769349526       rs769486921       rs769715814       rs769747382       rs769923290       rs769941971       rs769945357       rs770113730       rs770175691       rs770198475       rs770336915       rs770364311       rs770434470       rs770445331       rs770666062       rs770823815       rs770827515       rs771019983       rs771060572       rs771084588       rs771161376       rs771274855       rs771336967       rs771341828       rs771804603       rs771966034       rs771966122       rs772175272       rs772197020       rs772228560       rs772270729       rs772437451       rs772496048       rs772968023       rs773068466       rs773240595       rs773370283       rs773460981       rs773467964       rs773972518       rs774086130       rs774087209       rs774168526       rs774326892       rs774391962       rs774508787       rs774518759       rs774584953       rs774650042       rs774672179       rs774780522       rs774902997       rs774938843       rs775067281       rs775621500       rs775693856       rs775800947       rs775924831       rs776003444       rs776028482       rs776161771       rs776309978       rs776466438       rs776494595       rs776828873       rs776928091       rs777052454       rs777243811       rs777429787       rs777464618       rs777548980       rs777621556       rs777623052       rs777854336       rs777900227       rs777961432       rs778011121       rs778086830       rs778182933       rs778222282       rs778371144       rs778650234       rs778692620       rs778752885       rs778878899       rs778881075       rs779043642       rs779181816       rs779226183       rs779337377       rs779538659       rs779570528       rs779730310       rs779782008       rs780014870       rs780027563       rs780176949       rs780210418       rs780261558       rs780368864       rs780593904       rs780599445       rs780687866       rs780692720       rs780705722       rs780884253       rs780940163       rs781062377       rs781130471       rs781258292       rs781259988       rs781443436       rs781635699       rs781707071       rs781709751       rs781775699      

H19基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GTGACAAGCAGGACATGAC
58
CAGCCTAAGGTGTTCAGGA
59
TTTCTTTACTTCCTCCACGGA
59
GCACCATTTCTTTCATGTTGTG
59
CCACAACATGAAAGCTTGGA
59
AGGTCTGGTTCCTCTAGCT
59
TTTCTTTACTTCCTCCACGGA
59
GCACCATTTCTTTCATGTTGTG
59
CTTGGAAATGAATATGCTGCAC
59
TTCCTCTAGCTTCACCTTCC
59
TTTCTTTACTTCCTCCACGGA
59
GCACCATTTCTTTCATGTTGTG
59
CACAACATGAAAGAAATGGTGC
59
TTCATTTCCAAGCTAGAGGGT
59
GCTTGGAAATGAATATGCTGC
59
GTCTGGTTCCTCTAGCTTCC
60
TTTCTTTACTTCCTCCACGGA
59
GCACCATTTCTTTCATGTTGTG
59
GCTTGGAAATGAATATGCTGC
59
TCCTCTAGCTTCACCTTCC
58
      尚未收录相关数据

H19基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

H19基因的本体(GO)信息:

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控H19基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Beckwith-Wiedemann Syndrome 0.253059004 21 0 BeFree_CLINVAR_CTD_human_LHGDN
Russell-Silver syndrome 0.122985861 12 0 BeFree_CTD_human
Nephroblastoma 0.121357209 5 0 BeFree_ORPHANET
Hepatitis, Animal 0.12 1 0 CTD_human
Liver Neoplasms, Experimental 0.12 1 0 CTD_human
Congenital hemihypertrophy 0.12 0 0 ORPHANET
Familial Wilms tumor 2 0.12 0 0 CTD_human
Malignant neoplasm of breast 0.008186863 7 1 BeFree_GAD
Bladder Neoplasm 0.005720142 2 0 BeFree_LHGDN
Liver carcinoma 0.003810118 5 0 BeFree_LHGDN
Mammary Neoplasms 0.003267234 3 0 BeFree_LHGDN
Malignant neoplasm of urinary bladder 0.003181358 3 0 BeFree_GAD
Squamous cell carcinoma 0.002995792 2 0 BeFree_LHGDN
Congenital Abnormality 0.00272435 1 0 LHGDN
Rheumatoid Arthritis 0.00272435 1 0 LHGDN
Myeloproliferative disease 0.00272435 1 0 LHGDN
Ovarian Failure, Premature 0.00272435 1 0 LHGDN
Angiofibroma 0.00272435 1 0 LHGDN
Infection 0.00272435 1 0 LHGDN
Spontaneous abortion 0.002367032 1 0 GAD
Pre-Eclampsia 0.002367032 1 0 GAD
Pregnancy loss 0.002367032 1 0 GAD
Niemann-Pick Diseases 0.001900093 7 0 BeFree
Breast Carcinoma 0.001628651 6 1 BeFree
Carcinoma of bladder 0.001628651 6 0 BeFree
Diphtheria 0.000814326 3 0 BeFree
Neoplasm Metastasis 0.000814326 3 0 BeFree
Rhabdomyosarcoma 0.000814326 3 0 BeFree
Germ cell tumor 0.000814326 3 0 BeFree
Secondary malignant neoplasm of liver 0.000814326 3 0 BeFree
Adenocarcinoma 0.000542884 2 0 BeFree
Choriocarcinoma 0.000542884 2 0 BeFree
Embryonal Neoplasm 0.000542884 2 0 BeFree
Tumor Progression 0.000542884 2 0 BeFree
Hepatoblastoma 0.000542884 2 0 BeFree
Adrenal Cortical Adenoma 0.000542884 2 0 BeFree
Carcinogenesis 0.000542884 2 0 BeFree
Complete hydatidiform mole 0.000542884 2 0 BeFree
Gestational trophoblastic disease 0.000542884 2 0 BeFree
Adenoma 0.000271442 1 0 BeFree
Adrenal gland hypofunction 0.000271442 1 0 BeFree
Asthma 0.000271442 1 0 BeFree
beta Thalassemia 0.000271442 1 0 BeFree
Colorectal Carcinoma 0.000271442 1 0 BeFree
Cystic Fibrosis 0.000271442 1 0 BeFree
Diabetic Retinopathy 0.000271442 1 0 BeFree
Eclampsia 0.000271442 1 0 BeFree
Gigantism 0.000271442 1 0 BeFree
Glioma 0.000271442 1 0 BeFree
Klippel-Trenaunay-Weber Syndrome 0.000271442 1 0 BeFree
Fibroid Tumor 0.000271442 1 0 BeFree
Liver neoplasms 0.000271442 1 0 BeFree
Chronic Obstructive Airway Disease 0.000271442 1 0 BeFree
Malignant neoplasm of stomach 0.000271442 1 0 BeFree
Chloasma 0.000271442 1 0 BeFree
Inborn Errors of Metabolism 0.000271442 1 0 BeFree
Obesity 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
Prader-Willi Syndrome 0.000271442 1 0 BeFree
Retinoblastoma 0.000271442 1 0 BeFree
Schizoaffective Disorder 0.000271442 1 0 BeFree
Seminoma 0.000271442 1 0 BeFree
Dermatologic disorders 0.000271442 1 0 BeFree
Uterine Fibroids 0.000271442 1 0 BeFree
Lysosomal Storage Diseases 0.000271442 1 0 BeFree
Recurrent major depressive episodes 0.000271442 1 0 BeFree
Teratocarcinoma 0.000271442 1 0 BeFree
Adrenocortical carcinoma 0.000271442 1 0 BeFree
Rhabdoid Tumor 0.000271442 1 0 BeFree
Pancreatic carcinoma 0.000271442 1 0 BeFree
Bipolar II disorder 0.000271442 1 0 BeFree
Malignant neoplasm of lung 0.000271442 1 0 BeFree
Niemann-Pick Disease, Type B 0.000271442 1 0 BeFree
Liver and Intrahepatic Biliary Tract Carcinoma 0.000271442 1 0 BeFree
Malignant neoplasm of liver 0.000271442 1 0 BeFree
Malignant neoplasm of pancreas 0.000271442 1 0 BeFree
Malignant neoplasm of prostate 0.000271442 1 0 BeFree
Adrenal cortical hypofunction 0.000271442 1 0 BeFree
Prostate carcinoma 0.000271442 1 0 BeFree
Epithelial ovarian cancer 0.000271442 1 0 BeFree
Stomach Carcinoma 0.000271442 1 0 BeFree
Adult Acute Lymphocytic Leukemia 0.000271442 1 0 BeFree
Bipolar I disorder 0.000271442 1 0 BeFree
Malignant neoplasm of ovary 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree
Benign Prostatic Hyperplasia 0.000271442 1 0 BeFree
Skin Pigmentation Disorder 0.000271442 1 0 BeFree
Intrauterine Growth Retardation, Metaphyseal Dysplasia, Adrenal Hypoplasia Congenita, And Genital Anomalies 0.000271442 1 0 BeFree
HEMIHYPERPLASIA, ISOLATED 0.000271442 1 0 BeFree
Nasopharyngeal carcinoma 0.000271442 1 0 BeFree
Overgrowth Syndrome 0.000271442 1 0 BeFree
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