FLT3(fms-related tyrosine kinase 3)

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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13q12
基因染色体位置图

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]

[中文简述(自动翻译):]  这个基因编码,调节造血Ⅲ类受体酪氨酸激酶。这种受体是通过对细胞外结构域,其诱导在质膜,导致受体的自磷酸化同二聚体形成FMS相关酪氨酸激酶3配体的结合而活化。活化的受体激酶随后磷酸化并在参与细胞凋亡,增殖,和在骨髓造血细胞的分化途径激活多种细胞质效应分子。导致在急性骨髓性白血病和急性淋巴细胞性白血病该受体结果的组成性活化的突变。 [由RefSeq的,2015年1月提供]

FLT3基因的碱基序列:[NCBI]
FLT3基因的碱基突变:           显示全部snp
rs1316779       rs1319106       rs1319107       rs1320532       rs1320533       rs1320534       rs1320535       rs1320536       rs1344121       rs1815587       rs1815588       rs1933434       rs1933435       rs1933437       rs1933441       rs1962015       rs1962018       rs1999364       rs1999365       rs2007264       rs2095742       rs2152999       rs2153000       rs2185049       rs2185050       rs2282311       rs2387346       rs2387347       rs2387348       rs2387349       rs2387350       rs2387351       rs2387352       rs2387353       rs2387354       rs2387355       rs2387356      
rs2491216       rs2491217       rs2491218       rs2491219       rs2491220       rs2491221       rs2491222       rs2491223       rs2491224       rs2491225       rs2491226       rs2491227       rs2491228       rs2491229       rs2491230       rs2491231       rs2491232       rs2491233       rs2491234       rs2491235       rs2491236       rs2491237       rs2491238       rs2491239       rs2491240       rs2491241       rs2491242       rs2491243       rs2491244       rs2504224       rs2504225       rs2504226       rs2504227       rs2504228       rs2504229       rs2504230       rs2504231       rs2504232       rs2504233       rs2504234       rs2504235       rs2504236       rs2504237       rs3751392       rs3829382       rs3945023       rs4073630       rs4074542       rs4128996       rs4142559       rs4238206       rs4265672       rs4304889       rs4304898       rs4334131       rs4399415       rs4432111       rs4435098       rs4466945       rs4489853       rs4497507       rs4509870       rs4575382       rs4633554       rs4769589       rs4769590       rs4769591       rs4769592       rs4769593       rs4771203       rs4771205       rs4771206       rs4771207       rs4771208       rs4771209       rs4771210       rs4771217       rs4771218       rs4771219       rs4771220       rs4771221       rs5020785       rs5020786       rs5802456       rs5802457       rs5802458       rs5802460       rs5802463       rs5802464       rs6491247       rs6491248       rs6491249       rs6491250       rs6491251       rs6491252       rs6491254       rs6491255       rs6491256       rs6491257       rs6491258       rs6491259       rs6491260       rs6491261       rs7139620       rs7316962       rs7317159       rs7317427       rs7317540       rs7318118       rs7318228       rs7318543       rs7318817       rs7319062       rs7319630       rs7319898       rs7320820       rs7320980       rs7321051       rs7321212       rs7321730       rs7321811       rs7321960       rs7322165       rs7323163       rs7323345       rs7324080       rs7325615       rs7326082       rs7326210       rs7326846       rs7326955       rs7327072       rs7327222       rs7327568       rs7327579       rs7327609       rs7328200       rs7328298       rs7328699       rs7329160       rs7329518       rs7331012       rs7332042       rs7332632       rs7333532       rs7333646       rs7333811       rs7334180       rs7334327       rs7334951       rs7334993       rs7337222       rs7337390       rs7338112       rs7338206       rs7338211       rs7338445       rs7338746       rs7338903       rs7339100       rs7490828       rs7982889       rs7983026       rs7984591       rs7985005       rs7985206       rs7985425       rs7986910       rs7988090       rs7988463       rs7989343       rs7989654       rs7990001       rs7990705       rs7991154       rs7991531       rs7991620       rs7992631       rs7993032       rs7993161       rs7993593       rs7993639       rs7994155       rs7994899       rs7996986       rs7998462       rs8000938       rs8000945       rs8001423       rs8001744       rs8001973       rs8002065       rs9319410       rs9319412       rs9507976       rs9507977       rs9507978       rs9507983       rs9507984       rs9507985       rs9507986       rs9507987       rs9507988       rs9507989       rs9507991       rs9507993       rs9507995       rs9507996       rs9507997       rs9507998       rs9512971       rs9512974       rs9512975       rs9512977       rs9512978       rs9512979       rs9512980       rs9512982       rs9512984       rs9512985       rs9512986       rs9512987       rs9512988       rs9512989       rs9512990       rs9512994       rs9512995       rs9512996       rs9512998       rs9513000       rs9513001       rs9513002       rs9513004       rs9513005       rs9513006       rs9513010       rs9513011       rs9513012       rs9513013       rs9513018       rs9513019       rs9513020       rs9513021       rs9513022       rs9513023       rs9513025       rs9513026       rs9513027       rs9513028       rs9513029       rs9513030       rs9513032       rs9513034       rs9513035       rs9513036       rs9551427       rs9551428       rs9551429       rs9551431       rs9551432       rs9551433       rs9551434       rs9551435       rs9554220       rs9554221       rs9554222       rs9554223       rs9554224       rs9554226       rs9554228       rs9554229       rs9554230       rs9554231       rs9554232       rs9554233       rs9554234       rs9554235       rs9554236       rs9554237       rs9554238       rs9554239       rs9554242       rs9554243       rs9554244       rs9554245       rs9554246       rs9554247       rs9554250       rs9554251       rs9554252       rs9554254       rs9554255       rs9554258       rs9579141       rs9579142       rs9579143       rs9579149       rs9579150       rs9579151       rs9579153       rs9579155       rs9579156       rs9579157       rs9579159       rs9581958       rs9581959       rs9581960       rs9581961       rs9581966       rs9581967       rs9581968       rs9581970       rs9581971       rs9581972       rs9581973       rs9581974       rs9581975       rs9581976       rs9581977       rs9581978       rs9581979       rs9581980       rs9581982       rs9581983       rs9581984       rs9581985       rs9581986       rs9581987       rs9581988       rs9581992       rs9919866       rs9943908       rs9943947       rs10522717       rs10523017       rs10549768       rs10564719       rs10629301       rs10629302       rs10678675       rs10713102       rs10713103       rs10713286       rs10719225       rs11149508       rs11149512       rs11149513       rs11290476       rs11326702       rs11356393       rs11362058       rs11408684       rs11409962       rs11616501       rs11616983       rs11617968       rs11839568       rs11840250       rs11840268       rs11840651       rs11840665       rs11843543       rs12016790       rs12100232       rs12323019       rs12427653       rs12427992       rs12428172       rs12428707       rs12428920       rs12429639       rs12429764       rs12430047       rs12430855       rs12430881       rs12583162       rs12583184       rs12583420       rs12584289       rs12585696       rs12585699       rs12585779       rs12853651       rs12865238       rs12870188       rs12872232       rs12872889       rs12874529       rs13328999       rs17072037       rs17086212       rs17086213       rs17086214       rs17086226       rs17086239       rs17086242       rs17815013       rs28458275       rs28624847       rs28640144       rs28858374       rs34049926       rs34061361       rs34172843       rs34248726       rs34275171       rs34374211       rs34403610       rs34410286       rs34444701       rs34478396       rs34640894       rs34694672       rs34859171       rs34871309       rs34953042       rs35053802       rs35263155       rs35318238       rs35421108       rs35562724       rs35602083       rs35613052       rs35748326       rs35829721       rs35876607       rs35958982       rs36036463       rs41291684       rs55784328       rs55827368       rs55832899       rs55896931       rs56027115       rs56033040       rs56079720       rs56090538       rs56090729       rs56134396       rs56146647       rs56152292       rs56160015       rs56181669       rs56230494       rs56241602       rs56245749       rs56300022       rs56401390       rs56667135       rs56734235       rs56745762       rs57182658       rs57260336       rs57536690       rs57834076       rs58216834       rs58274312       rs58436405       rs58483438       rs58490213       rs58495889       rs58553214       rs58636808       rs58666235       rs58697430       rs59079187       rs59083233       rs59251752       rs59295983       rs59324859       rs59332776       rs59333724       rs59427352       rs59686303       rs59703277       rs59718306       rs59917555       rs59947907       rs59951785       rs59970838       rs60015913       rs60288953       rs60377947       rs60601341       rs60643580       rs60649910       rs60783479       rs60881931       rs60945034       rs61305454       rs61306503       rs61729139       rs61729144       rs61944199       rs61944200       rs61944202       rs61944699       rs61944700       rs61944701       rs61944702       rs61944703       rs61944745       rs61944746       rs61944747       rs61944748       rs61944749       rs61944750       rs61946324       rs61946325       rs61953165       rs61953166       rs61953168       rs62636526       rs66520040       rs66936596       rs66976696       rs67034446       rs67152931       rs67491524       rs67617046       rs71086818       rs71086821       rs71086829       rs71086830       rs71188800       rs71209457       rs71433252       rs71433253       rs71433254       rs71433255       rs71707980       rs73154803       rs73154805       rs73154811       rs73154813       rs73154816       rs73154818       rs73154819       rs73154821       rs73154822       rs73154826       rs73154827       rs73154830       rs73154832       rs73154834       rs73154835       rs73154838       rs73154839       rs73154840       rs73154842       rs73154845       rs73154871       rs73154872       rs73154873       rs73154874       rs73154875       rs73154877       rs73154879       rs73156237       rs73156246       rs73156252       rs73156256       rs73156257       rs73156261       rs73171839       rs73171840       rs73171849       rs73436930       rs73436932       rs73436937       rs73436951       rs73436958       rs73436963       rs73436965       rs73436967       rs73436969       rs73436978       rs73436994       rs73436997       rs73439107       rs73439112       rs73439117       rs73439124       rs73439128       rs73439133       rs73439135       rs73439141       rs73439142       rs73439151       rs73439156       rs73439158       rs73439159       rs73439160       rs73439168       rs73443025       rs73443056       rs73443058       rs73445029       rs74041525       rs74041526       rs74041527       rs74041528       rs74041530       rs74041531       rs74041569       rs74315691       rs74385939       rs74386401       rs74395381       rs74411310       rs74496226       rs74533457       rs74601498       rs74653167       rs74674063       rs74753866       rs74785823       rs74830356       rs74892171       rs74897025       rs74931192       rs74938683       rs74977813       rs75035087       rs75212970       rs75229013       rs75353434       rs75469608       rs75510362       rs75558585       rs75561253       rs75580865       rs75651252       rs75658740       rs75663522       rs75672611       rs75684486       rs75732161       rs75733909       rs75795767       rs75844510       rs75849452       rs75901840       rs75906513       rs75953444       rs76080105       rs76253728       rs76280316       rs76402639       rs76413244       rs76420491       rs76428106       rs76496087       rs76499898       rs76510558       rs76520208       rs76559498       rs76656552       rs76660253       rs76671509       rs76691432       rs76725075       rs76806775       rs76816674       rs76862245       rs76935128       rs76941284       rs76967072       rs76968004       rs76991010       rs77117752       rs77145661       rs77163884       rs77307219       rs77415257       rs77494640       rs77541997       rs77664614       rs77795141       rs77858976       rs77886845       rs78128199       rs78158228       rs78195386       rs78262084       rs78321923       rs78333994       rs78337850       rs78432192       rs78525779       rs78534741       rs78564726       rs78623455       rs78675579       rs78763053       rs78799753       rs78816694       rs78854330       rs78976457       rs78999685       rs79076694       rs79133683       rs79185559       rs79233994       rs79240208       rs79285213       rs79370764       rs79386735       rs79393634       rs79443734       rs79490353       rs79520143       rs79566936       rs79634806       rs79643596       rs79878151       rs79886841       rs79904397       rs79983705       rs79999978       rs80080011       rs80133756       rs80133999       rs80168985       rs80217347       rs80265446       rs80287309       rs80316734       rs80327094       rs111237065       rs111253099       rs111331965       rs111332770       rs111354172       rs111391824       rs111404906       rs111405637       rs111410747       rs111457997       rs111523582       rs111545794       rs111550663       rs111552438       rs111560962       rs111584359       rs111641619       rs111646224       rs111658373       rs111682752       rs111686505       rs111716728       rs111736205       rs111743470       rs111765559       rs111804058       rs111815045       rs111819652       rs111861564       rs111863688       rs111892726       rs111918573       rs111969814       rs112031550       rs112047573       rs112074395       rs112091646       rs112095409       rs112120556       rs112162122       rs112163489       rs112211042       rs112218934       rs112239602       rs112243961       rs112279439       rs112405720       rs112419015       rs112438065       rs112490222       rs112495308       rs112497182       rs112621869       rs112682868       rs112692793       rs112701727       rs112837198       rs112885152       rs112894074       rs112922107       rs112981954       rs112992901       rs113003217       rs113014930       rs113045642       rs113061043       rs113088377       rs113133355       rs113143173       rs113186449       rs113187201       rs113205475       rs113206407       rs113326513       rs113333944       rs113377392       rs113414265       rs113421711       rs113428661       rs113430386       rs113432071       rs113546045       rs113549372       rs113567190       rs113600669       rs113629845       rs113630094       rs113636293       rs113676020       rs113681403       rs113698507       rs113710480       rs113727636       rs113780656       rs113784426       rs113796080       rs113835369       rs113838405       rs113854027       rs113917121       rs113935225       rs113937296       rs113947550       rs113969348       rs113969458       rs113983632       rs114092460       rs114115329       rs114199142       rs114407645       rs114507141       rs114553060       rs114690061       rs114826735       rs114897165       rs114975182       rs114983113       rs115084655       rs115327615       rs115407541       rs115466624       rs115540379       rs115543420       rs115597850       rs115631298       rs115634130       rs115655895       rs115746886       rs115820563       rs115832381       rs115939671       rs115955638       rs116014403       rs116137629       rs116373872       rs116378425       rs116409867       rs116474561       rs116504326       rs116566542       rs116718849       rs116721996       rs116754560       rs116783104       rs116850180       rs116885747       rs116986292       rs117045645       rs117145034       rs117188311       rs117190100       rs117240821       rs117276254       rs117343789       rs117390028       rs117393774       rs117415415       rs117673365       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rs751879706       rs751920513       rs751928780       rs751964987       rs751982273       rs752092807       rs752191320       rs752394054       rs752448694       rs752449869       rs752457971       rs752501348       rs752552418       rs752674589       rs752729752       rs752745594       rs752754459       rs752845285       rs752904586       rs753054124       rs753080745       rs753139402       rs753172215       rs753200838       rs753260490       rs753260826       rs753361791       rs753528763       rs753540050       rs753564778       rs753586148       rs753586227       rs753639225       rs753854207       rs753870201       rs753876149       rs753905654       rs754039652       rs754089634       rs754142696       rs754176049       rs754285520       rs754356487       rs754396362       rs754418964       rs754505388       rs754562079       rs754584175       rs754604134       rs754639044       rs754692199       rs754728586       rs754764685       rs754803842       rs754816108       rs754861142       rs754904480       rs755081448       rs755119728       rs755147104       rs755162946       rs755180272       rs755206983       rs755233667       rs755381883       rs755397430       rs755423056       rs755691324       rs755720573       rs755786789       rs755788921       rs755845031       rs755958790       rs755980475       rs756002946       rs756030353       rs756072254       rs756312050       rs756377225       rs756430183       rs756580988       rs756684686       rs756700189       rs756806901       rs756857154       rs756942689       rs756945583       rs757099771       rs757151045       rs757157975       rs757492638       rs757518348       rs757519348       rs757572340       rs757663838       rs757670191       rs757718855       rs757792006       rs757954859       rs758095462       rs758146765       rs758200027       rs758240051       rs758295657       rs758604156       rs758631139       rs758649164       rs758657093       rs758661872       rs758754526       rs758850662       rs758906408       rs758953385       rs758974112       rs759226906       rs759278648       rs759299301       rs759369573       rs759474779       rs759527795       rs759638195       rs759674820       rs759729774       rs759759571       rs759781160       rs759887579       rs759943272       rs759986816       rs760059521       rs760081935       rs760330378       rs760407576       rs760485979       rs760501675       rs760605631       rs760751139       rs760803197       rs760834055       rs760981462       rs761045044       rs761173782       rs761185360       rs761205916       rs761250180       rs761284186       rs761305303       rs761451687       rs761483483       rs761555525       rs761574342       rs761621550       rs761757421       rs761880634       rs761909645       rs761932040       rs761962746       rs762000524       rs762012802       rs762198688       rs762242697       rs762269059       rs762305411       rs762390598       rs762392769       rs762424747       rs762511994       rs762533143       rs762585560       rs762630497       rs762658760       rs762685670       rs762755527       rs762768197       rs762965899       rs762970489       rs763023562       rs763143926       rs763278335       rs763324475       rs763475567       rs763541713       rs763575237       rs763633405       rs763688464       rs763689906       rs763948782       rs764025365       rs764027375       rs764075004       rs764080369       rs764151292       rs764257600       rs764288814       rs764307933       rs764308917       rs764406387       rs764656426       rs764665398       rs764732883       rs764770806       rs764776316       rs764827742       rs765114589       rs765165741       rs765165981       rs765227645       rs765282935       rs765284994       rs765337935       rs765370822       rs765381408       rs765418650       rs765554376       rs765576611       rs765606901       rs765617190       rs765625199       rs765715484       rs765864291       rs765903663       rs765915217       rs766010781       rs766061285       rs766230032       rs766285197       rs766309690       rs766421025       rs766424980       rs766480411       rs766620089       rs766677410       rs766680131       rs766704135       rs766805610       rs766824698       rs766845230       rs766953291       rs767025952       rs767052933       rs767077062       rs767299779       rs767343987       rs767347946       rs767430269       rs767471673       rs767657203       rs768002750       rs768037290       rs768037348       rs768105517       rs768238783       rs768242826       rs768278274       rs768333323       rs768372769       rs768385382       rs768405963       rs768433360       rs768440707       rs768712781       rs768723625       rs768828525       rs769106403       rs769122661       rs769160255       rs769234618       rs769235927       rs769394501       rs769422297       rs769621719       rs769640419       rs769718751       rs769807030       rs769857405       rs769858392       rs769899577       rs769918229       rs769921000       rs769950416       rs770221306       rs770253125       rs770301265       rs770309879       rs770337450       rs770392736       rs770523096       rs770571247       rs770575812       rs770630954       rs770772264       rs770823638       rs770826962       rs771026159       rs771026522       rs771079228       rs771087435       rs771093551       rs771100488       rs771192859       rs771300239       rs771353499       rs771374320       rs771427666       rs771459807       rs771577500       rs771602262       rs771655661       rs771726006       rs771849609       rs771849788       rs772006161       rs772061268       rs772078021       rs772118022       rs772146579       rs772243418       rs772278392       rs772310337       rs772468040       rs772553557       rs772714284       rs772714344       rs772715363       rs772854825       rs772894088       rs772907680       rs772958466       rs772963831       rs773063445       rs773085573       rs773093005       rs773134567       rs773189409       rs773272572       rs773277609       rs773310118       rs773412677       rs773417784       rs773466203       rs773749124       rs773758373       rs773802462       rs773809653       rs773883670       rs773885555       rs773923352       rs773932256       rs773968505       rs773983010       rs774047080       rs774131453       rs774162586       rs774215795       rs774257127       rs774344038       rs774360726       rs774504626       rs774511256       rs774540041       rs774626768       rs774682624       rs774881420       rs774882266       rs774936542       rs775034143       rs775057940       rs775176653       rs775314249       rs775365687       rs775383158       rs775443081       rs775634768       rs775693739       rs775744646       rs775755684       rs775807044       rs775945126       rs775998708       rs776000316       rs776003598       rs776133815       rs776184675       rs776193252       rs776386970       rs776422691       rs776498341       rs776576377       rs776640120       rs776699712       rs776770373       rs776826985       rs776829493       rs776880433       rs776892297       rs776952835       rs777024583       rs777075116       rs777127892       rs777210242       rs777457578       rs777508330       rs777510370       rs777517159       rs777568185       rs777621655       rs777706542       rs777797916       rs777901691       rs777905087       rs777964531       rs777975044       rs778068222       rs778119340       rs778185695       rs778216126       rs778256828       rs778399371       rs778565623       rs778585125       rs778587791       rs778614556       rs778646065       rs778838305       rs778898414       rs779093897       rs779097862       rs779125398       rs779139489       rs779148945       rs779282825       rs779318784       rs779336061       rs779344671       rs779366241       rs779621944       rs779681590       rs779688631       rs779699008       rs779723817       rs779732953       rs779748188       rs779838813       rs779912505       rs779919727       rs780372708       rs780421585       rs780425575       rs780435520       rs780474886       rs780604821       rs780762819       rs780763344       rs780791387       rs780825221       rs780849820       rs780941129       rs781049215       rs781248096       rs781258193       rs781309826       rs781339959       rs781482511       rs781502682       rs781503740       rs781557651       rs781612808       rs781675235       rs781732167       rs867385616       rs869130116       rs869230631      

FLT3基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GAAGAAGCGAAACTGTGGA
58
CTTTGTGTTACCCTTGTCCT
58
GAAGAAGCGAAACTGTGGA
58
CCTTTGTGTTACCCTTGTCC
59
CAAATTCCAGCATGCCTGG
60
ATGAATTCCCATGAAGCCCT
60
CCAAATTCCAGCATGCCTG
60
TGAATTCCCATGAAGCCCT
59
AGAAGAAGCGAAACTGTGG
58
CTTTGTGTTACCCTTGTCCT
58
ATCCAAATTCCAGCATGCC
59
GAATTCCCATGAAGCCCTG
59
CAAAGCTGTTCATGTGAACC
58
TCAAAGTAGTTGCCCTCCT
58
TGTTTCTCGGATGGATACCC
59
GATCTCTTCTGTGCAGTTGG
59
CAAAGCTGTTCATGTGAACCA
60
TCAAAGTAGTTGCCCTCCTC
60
      尚未收录相关数据

FLT3基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

FLT3基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0004714
E7ER61(UniProtKB)
IEA
GO:0005524
E7ER61(UniProtKB)
IEA
GO:0007169
E7ER61(UniProtKB)
IEA
GO:0016021
E7ER61(UniProtKB)
IEA
GO:0018108
E7ER61(UniProtKB)
IEA
GO:0030097
E7ER61(UniProtKB)
IEA
GO:0030154
E7ER61(UniProtKB)
IEA
GO:0001776
P36888(UniProtKB)
ISS
GO:0002318
P36888(UniProtKB)
ISS
GO:0002328
P36888(UniProtKB)
ISS
GO:0004714
P36888(UniProtKB)
TAS
GO:0004896
P36888(UniProtKB)
ISS
GO:0005021
P36888(UniProtKB)
TAS
GO:0005515
P36888(UniProtKB)
IPI
GO:0005515
P36888(UniProtKB)
IPI
GO:0005515
P36888(UniProtKB)
IPI
GO:0005515
P36888(UniProtKB)
IPI
GO:0005524
P36888(UniProtKB)
IEA
GO:0005634
P36888(UniProtKB)
IEA
GO:0005788
P36888(UniProtKB)
IEA
GO:0005829
P36888(UniProtKB)
IEA
GO:0005886
P36888(UniProtKB)
TAS
GO:0005886
P36888(UniProtKB)
TAS
GO:0005887
P36888(UniProtKB)
TAS
GO:0007169
P36888(UniProtKB)
TAS
GO:0008284
P36888(UniProtKB)
TAS
GO:0010243
P36888(UniProtKB)
IEA
GO:0014068
P36888(UniProtKB)
TAS
GO:0018108
P36888(UniProtKB)
TAS
GO:0019221
P36888(UniProtKB)
ISS
GO:0030097
P36888(UniProtKB)
IDA
GO:0030183
P36888(UniProtKB)
ISS
GO:0031100
P36888(UniProtKB)
IEA
GO:0032403
P36888(UniProtKB)
IEA
GO:0035259
P36888(UniProtKB)
IEA
GO:0035726
P36888(UniProtKB)
ISS
GO:0038084
P36888(UniProtKB)
IEA
GO:0042531
P36888(UniProtKB)
TAS
GO:0042803
P36888(UniProtKB)
TAS
GO:0042981
P36888(UniProtKB)
TAS
GO:0043234
P36888(UniProtKB)
IEA
GO:0043406
P36888(UniProtKB)
TAS
GO:0043410
P36888(UniProtKB)
TAS
GO:0043552
P36888(UniProtKB)
TAS
GO:0046651
P36888(UniProtKB)
ISS
GO:0046777
P36888(UniProtKB)
TAS
GO:0071345
P36888(UniProtKB)
ISS
GO:0071345
P36888(UniProtKB)
TAS
GO:0071385
P36888(UniProtKB)
IEA
GO:0097028
P36888(UniProtKB)
ISS
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控FLT3基因的相关microRNA:      显示全部miRNA


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Leukemia, Myelocytic, Acute 0.56 707 10 BeFree_CLINVAR_CTD_human_GAD_LHGDN_MGD
Acute Promyelocytic Leukemia 0.146588829 46 0 BeFree_CTD_human_GAD_LHGDN
Acute lymphocytic leukemia 0.130314791 38 3 BeFree_CLINVAR
Acute biphenotypic leukemia 0.12 0 0 ORPHANET
Thrombosis 0.12 1 0 CTD_human
LEUKEMIA, ACUTE LYMPHOBLASTIC, SUSCEPTIBILITY TO, 3 0.12 0 0 ORPHANET
leukemia 0.093278617 151 1 BeFree_GAD_LHGDN
Juvenile Myelomonocytic Leukemia 0.080542884 2 0 BeFree_MGD
Arthritis, Experimental 0.08 1 0 RGD
Myeloid Leukemia 0.056970589 30 1 BeFree_GAD_LHGDN
Precursor Cell Lymphoblastic Leukemia Lymphoma 0.034228927 37 0 BeFree_GAD_LHGDN
MYELODYSPLASTIC SYNDROME 0.026804189 22 0 BeFree_GAD_LHGDN
Preleukemia 0.011715608 20 0 BeFree_GAD
Neoplasm, Residual 0.011605987 24 0 BeFree_GAD_LHGDN
Acute leukemia 0.010857675 40 0 BeFree
Leukemogenesis 0.009229024 34 0 BeFree
Cytogenetically normal acute myeloid leukemia 0.008143256 30 0 BeFree
Myeloid Leukemia, Chronic 0.007991366 14 2 BeFree_GAD
pediatric acute myeloblastic leukemia 0.007600372 28 0 BeFree
Adult Acute Myeloblastic Leukemia 0.006514605 24 0 BeFree
Leukemia, Myelomonocytic, Chronic 0.006091273 7 2 BeFree_GAD
Down Syndrome 0.005362824 2 0 BeFree_GAD_LHGDN
Hematologic Neoplasms 0.004895885 8 0 BeFree_LHGDN
Chromosome Aberrations 0.004734064 2 0 GAD
Myeloproliferative disease 0.00434307 16 0 BeFree
Lymphoid leukemia 0.003452799 5 0 BeFree_GAD
MULTICYSTIC RENAL DYSPLASIA, BILATERAL 0.003257302 12 0 BeFree
Leukocytosis 0.00272435 1 0 LHGDN
Alcoholic Intoxication, Chronic 0.002367032 1 0 GAD
Neoplastic Cell Transformation 0.002367032 1 0 GAD
Lymphoproliferative Disorders 0.002367032 1 0 GAD
Pathologic Neovascularization 0.002367032 1 0 GAD
Osteoporosis 0.002367032 1 0 GAD
Pancreatic Neoplasm 0.002367032 1 0 GAD
Tobacco Use Disorder 0.002367032 1 0 GAD
Chromosomal translocation 0.002367032 1 0 GAD
XYY Karyotype 0.002367032 1 0 GAD
Congenital chromosomal disease 0.001628651 6 0 BeFree
Leukemia, Lymphocytic, Acute, L1 0.001628651 6 0 BeFree
Nephroblastoma 0.001628651 6 0 BeFree
secondary acute myeloid leukemia 0.001628651 6 0 BeFree
Acute monocytic leukemia 0.001357209 5 0 BeFree
Hematopoietic Neoplasms 0.001357209 5 0 BeFree
Neuroblastoma 0.001085767 4 0 BeFree
Refractory cancer 0.001085767 4 0 BeFree
Central neuroblastoma 0.001085767 4 0 BeFree
Precursor B-cell lymphoblastic leukemia 0.001085767 4 0 BeFree
Chronic myeloproliferative disorder 0.001085767 4 0 BeFree
Hyperdiploid B Acute Lymphoblastic Leukemia 0.001085767 4 0 BeFree
Monosomy 0.000814326 3 0 BeFree
Acute Myeloid Leukemia Arising from Previous Myelodysplastic Syndrome 0.000814326 3 0 BeFree
Core binding factor acute myeloid leukemia 0.000814326 3 0 BeFree
Refractory anaemia with excess blasts 0.000542884 2 0 BeFree
Autoimmune Diseases 0.000542884 2 0 BeFree
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 0.000542884 2 0 BeFree
Lymphoma 0.000542884 2 0 BeFree
Myelodysplasia 0.000542884 2 0 BeFree
Acute Myeloid Leukemia, M1 0.000542884 2 0 BeFree
Patau syndrome 0.000542884 2 0 BeFree
Granulocytic Sarcoma 0.000542884 2 0 BeFree
Mastocytosis, Systemic 0.000542884 2 0 BeFree
Pancreatic carcinoma 0.000542884 2 0 BeFree
Miller Dieker syndrome 0.000542884 2 0 BeFree
Refractory anemia with excess blasts in transformation (clinical) 0.000542884 2 0 BeFree
Malignant neoplasm of pancreas 0.000542884 2 0 BeFree
Trisomy 11 0.000542884 2 0 BeFree
Chromosome 8, trisomy 0.000542884 2 0 BeFree
Thyroid carcinoma 0.000542884 2 0 BeFree
M5b Acute differentiated monocytic leukemia 0.000542884 2 0 BeFree
Treatment related acute myeloid leukaemia 0.000542884 2 0 BeFree
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 0.000542884 2 0 BeFree
Promyelocytic leukemia 0.000542884 2 0 BeFree
Refractory anemias 0.000271442 1 0 BeFree
Arthritis 0.000271442 1 0 BeFree
Blast Phase 0.000271442 1 0 BeFree
Brain Neoplasms 0.000271442 1 0 BeFree
Colorectal Carcinoma 0.000271442 1 0 BeFree
Dermatitis 0.000271442 1 0 BeFree
Diabetes 0.000271442 1 0 BeFree
Diabetes Mellitus 0.000271442 1 0 BeFree
Eosinophilia 0.000271442 1 0 BeFree
Glioma 0.000271442 1 0 BeFree
Graft-vs-Host Disease 0.000271442 1 0 BeFree
Hematological Disease 0.000271442 1 0 BeFree
Herpes Simplex Infections 0.000271442 1 0 BeFree
Immunologic Deficiency Syndromes 0.000271442 1 0 BeFree
Chronic Lymphocytic Leukemia 0.000271442 1 0 BeFree
Hairy Cell Leukemia 0.000271442 1 0 BeFree
Leukopenia 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Neoplasms, Experimental 0.000271442 1 0 BeFree
Obesity 0.000271442 1 0 BeFree
Paraplegia 0.000271442 1 0 BeFree
Polycythemia Vera 0.000271442 1 2 BeFree
Psoriasis 0.000271442 1 0 BeFree
Dermatologic disorders 0.000271442 1 0 BeFree
Germ cell tumor 0.000271442 1 0 BeFree
Neuroectodermal Tumors 0.000271442 1 0 BeFree
Neuroectodermal Tumor, Primitive 0.000271442 1 0 BeFree
Trisomy 22 0.000271442 1 0 BeFree
relapsing chronic myelogenous leukemia 0.000271442 1 0 BeFree
T-cell adult acute lymphoblastic leukemia 0.000271442 1 0 BeFree
childhood acute promyelocytic leukemia (M3) 0.000271442 1 0 BeFree
Extraosseous Ewings sarcoma-primitive neuroepithelial tumor 0.000271442 1 0 BeFree
Acute Undifferentiated Leukemia 0.000271442 1 0 BeFree
Sarcoma of breast 0.000271442 1 0 BeFree
Ewings sarcoma 0.000271442 1 0 BeFree
Hypofibrinogenemia 0.000271442 1 0 BeFree
Lymphoid neoplasm 0.000271442 1 0 BeFree
Ewings sarcoma-primitive neuroectodermal tumor (PNET) 0.000271442 1 0 BeFree
Hypereosinophilia 0.000271442 1 0 BeFree
Adult Acute Lymphocytic Leukemia 0.000271442 1 0 BeFree
Myelosuppression 0.000271442 1 0 BeFree
Rhabdoid Tumor of the Kidney 0.000271442 1 0 BeFree
Neutrophilic dermatosis 0.000271442 1 0 BeFree
Sarcoma 0.000271442 1 0 BeFree
Therapy-related myelodysplastic syndrome 0.000271442 1 0 BeFree
Mast cell malignancy 0.000271442 1 0 BeFree
Eosinophilic disorder 0.000271442 1 0 BeFree
Undifferentiated leukemia 0.000271442 1 0 BeFree
Mammary Neoplasms 0.000271442 1 0 BeFree
Xenograft Model 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree
Chronic myeloid leukemia in lymphoid blast crisis 0.000271442 1 0 BeFree
Glioblastoma Multiforme 0.000271442 1 0 BeFree
Disorder characterized by eosinophilia 0.000271442 1 0 BeFree
Leukemia, B-Cell 0.000271442 1 0 BeFree
Extramedullary Hematopoiesis (disorder) 0.000271442 1 0 BeFree
Acute Myeloid Leukemia with Myelodysplasia-Related Changes 0.000271442 1 0 BeFree
Treatment related leukaemia 0.000271442 1 0 BeFree
Acute myeloid leukemia with mutated CEBPA 0.000271442 1 0 BeFree
Neural crest tumor 0.000271442 1 0 BeFree
Refractory anemia, without ringed sideroblasts, without excess blasts 0.000271442 1 0 BeFree
Intracranial glioma 0.000271442 1 0 BeFree
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