CCR5(chemokine (C-C motif) receptor 5 (gene/pseudogene))

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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3p21
基因染色体位置图

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  该基因编码的测试趋化因子受体家族,其被预测为类似于G蛋白偶联受体具有七次跨膜蛋白的成员。该蛋白质是由T细胞和巨噬细胞中表达,并且被称为是一个重要的共同受体为巨噬细胞热带病毒,包括HIV,进入宿主细胞。这种基因有缺陷的等位基因已与艾滋病毒感染的抵抗力有关。该受体的配体包括单核细胞趋化蛋白2(MCP-2),巨噬细胞炎性蛋白1α(MIP-1α),巨噬细胞炎性蛋白1β(MIP-1β)和调节活化正常T表达和分泌蛋白( RANTES)。在一个promyeloblastic细胞系也检测出该基因的表达,这表明该蛋白可能在粒细胞增殖和分化的作用。该基因位于趋化因子受体基因簇的区域。已发现了该基因编码的蛋白质相同的两个转录变异体。 [由RefSeq的,2008年7月提供]

CCR5基因的碱基序列:[NCBI]
CCR5基因的碱基突变:           显示全部snp
rs333       rs746492       rs1799863       rs1799987       rs1799988       rs1800023       rs1800024       rs1800452       rs1800560       rs1800874       rs1800939       rs1800940       rs1800941       rs1800942       rs1800944       rs1800945       rs2157060       rs2227010       rs2254089       rs2734225       rs2734648       rs2856757       rs2856758       rs2856761       rs2856762       rs2856764       rs2856765       rs3087247       rs3087248       rs3087249       rs3087250       rs3136536       rs3176763       rs3181037       rs3188094       rs3216198       rs4987054      
rs9282631       rs9282632       rs17765882       rs28620009       rs34418657       rs41339446       rs41345848       rs41352147       rs41365248       rs41382446       rs41384848       rs41386445       rs41395049       rs41395249       rs41403149       rs41412948       rs41418945       rs41425744       rs41442546       rs41458950       rs41466044       rs41469351       rs41469750       rs41475349       rs41490645       rs41491345       rs41495153       rs41499550       rs41512547       rs41515644       rs41526948       rs41535253       rs55639502       rs55916127       rs55956105       rs56198941       rs56340326       rs56345960       rs67109155       rs76436340       rs111233598       rs112622745       rs112762802       rs113471490       rs113552054       rs113869679       rs137866928       rs138174483       rs138380934       rs138621551       rs139018793       rs139737901       rs140523021       rs140587963       rs140653397       rs141139165       rs141257116       rs141737357       rs142076881       rs142469507       rs142620835       rs142710698       rs142829420       rs142904831       rs142957506       rs143181119       rs143589063       rs143602732       rs143788172       rs143880323       rs144255721       rs145061115       rs145146492       rs145371166       rs145725153       rs145751198       rs146080174       rs146209111       rs146556912       rs146926765       rs146972949       rs147420214       rs147615392       rs147879075       rs148007422       rs148106779       rs148802293       rs149509262       rs149622978       rs149975182       rs149977098       rs150450395       rs150497029       rs150592242       rs150855419       rs151122728       rs151126808       rs181641346       rs181867134       rs182052831       rs182646932       rs183662584       rs183753875       rs183840358       rs184040468       rs184279915       rs184985767       rs185207041       rs185327310       rs186138215       rs186352754       rs186785168       rs186889269       rs187838508       rs188423028       rs188577829       rs188772198       rs189601230       rs189663620       rs190094030       rs190136403       rs190456231       rs190462461       rs191230884       rs191297617       rs191374074       rs192002630       rs192256035       rs192425331       rs192798693       rs193039140       rs199722561       rs199780106       rs199824195       rs199846907       rs200209014       rs200419576       rs201063877       rs201179081       rs201290940       rs201423367       rs201780857       rs201797884       rs202002844       rs367851873       rs368391698       rs369206494       rs369351284       rs369373756       rs369515918       rs370386700       rs370409212       rs371598347       rs371813238       rs371901382       rs372054532       rs372782701       rs372786661       rs372879037       rs373358134       rs373926603       rs374426321       rs374495269       rs374959868       rs375777270       rs375916464       rs376137306       rs376306118       rs376364792       rs376687230       rs377330713       rs527678371       rs528022257       rs528203079       rs528671807       rs528738443       rs529519962       rs529547367       rs529611447       rs529688443       rs529752751       rs530424450       rs531662647       rs531725192       rs532474349       rs532495909       rs532949499       rs533537621       rs533626678       rs533695265       rs534088482       rs534240555       rs534304693       rs534316499       rs534497551       rs534677585       rs535314315       rs535792329       rs535892345       rs536770486       rs536872608       rs537300448       rs537491506       rs538757349       rs539027881       rs539832725       rs539953254       rs540267036       rs540976580       rs540992448       rs541069027       rs541210726       rs541845196       rs542055812       rs542780938       rs543450476       rs543579626       rs543618933       rs543680286       rs544310461       rs544455720       rs545373945       rs546683708       rs547510206       rs547721330       rs547916512       rs547959533       rs548727619       rs549083541       rs549206526       rs549257838       rs550248476       rs550385921       rs550471410       rs550958125       rs550991942       rs551196542       rs551297914       rs551771466       rs551859885       rs551901023       rs552107409       rs552382275       rs553155294       rs553230690       rs554369038       rs555028689       rs555631895       rs556224798       rs556969790       rs556971174       rs556982385       rs557102493       rs557149889       rs558483026       rs559194526       rs559344601       rs559783442       rs560812992       rs561352865       rs562091107       rs562220468       rs562961861       rs563025816       rs563118331       rs563153875       rs563762909       rs563823814       rs565029190       rs565095660       rs565628795       rs566824961       rs567947618       rs568368266       rs568574805       rs568718768       rs568854883       rs569344707       rs569433974       rs569458865       rs569580492       rs570463527       rs570721731       rs570782804       rs571339706       rs571452708       rs572814964       rs572840507       rs573333280       rs573714896       rs574835762       rs574865763       rs574892806       rs574954754       rs575169866       rs575840249       rs577113895       rs577174845       rs745372153       rs745912425       rs746214124       rs746300015       rs746626584       rs746772498       rs746860511       rs746899041       rs747065935       rs747196580       rs747388089       rs747396322       rs747625967       rs747754051       rs747951371       rs747999011       rs748154509       rs748699284       rs748811682       rs748818705       rs749113400       rs750002181       rs750032774       rs750227516       rs750682026       rs750809479       rs750894443       rs751252593       rs751323475       rs751446924       rs751603911       rs751650495       rs752265311       rs753095965       rs753300247       rs753392986       rs753901059       rs754530124       rs754799423       rs754955483       rs755334689       rs755442066       rs755563272       rs755938296       rs755948362       rs756101518       rs756257015       rs756310938       rs756597818       rs757171495       rs757294302       rs757377300       rs757918238       rs758090461       rs758662716       rs758937078       rs759132997       rs759216579       rs759344760       rs759473231       rs759590067       rs759632621       rs759745875       rs760428955       rs761483454       rs761967907       rs762167048       rs762209242       rs762613473       rs762888354       rs762989437       rs763103073       rs763192695       rs763264245       rs763433060       rs763623180       rs763770533       rs764278401       rs764318467       rs764368335       rs764687756       rs764761704       rs765009973       rs765063799       rs765239542       rs765254357       rs765467514       rs765993128       rs766082963       rs766182681       rs766432600       rs766509880       rs766874061       rs766967187       rs767205045       rs767459001       rs767604123       rs767935035       rs768195565       rs768257027       rs768291615       rs768338339       rs768398484       rs769009812       rs769057798       rs769213005       rs769515720       rs770002247       rs770335913       rs770608463       rs771244514       rs771443021       rs771817175       rs771917529       rs772239843       rs772422768       rs772530777       rs772685815       rs772758049       rs772879956       rs773341558       rs773768514       rs773818071       rs774050135       rs774482480       rs774845977       rs775289875       rs775290065       rs775644923       rs775737126       rs776305643       rs776341341       rs776432250       rs776859902       rs777330502       rs777349996       rs777351934       rs777374937       rs777539326       rs777744606       rs777849486       rs778497859       rs779328542       rs779364675       rs779454060       rs779570167       rs780012517       rs780235820       rs780481847       rs781160743       rs781530599       rs781613165       rs781713216      

CCR5基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ATCTTCTTCATCATCCTCCTGAC
60
CAAACACAGCATGGACGAC
60
TCACTGGTGTTCATCTTTGG
58
AGTTTATCAGGATGAGGATGAC
58
AGAAGAGCTGAGACATCCG
59
GGACTTGACACTTGATAATCCA
58
GAAGAGCTGAGACATCCGT
59
TGGACTTGACACTTGATAATCC
58
CAACATGCTGGTCATCCTC
59
GATGTCAGTCATGCTCTTCAG
59
GAAGAGCTGAGACATCCGT
59
GGACTTGACACTTGATAATCCA
58
      尚未收录相关数据

CCR5基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

CCR5基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0000165
P51681(UniProtKB)
IEP
GO:0001618
P51681(UniProtKB)
IEA
GO:0002407
P51681(UniProtKB)
TAS
GO:0003779
P51681(UniProtKB)
IDA
GO:0004435
P51681(UniProtKB)
TAS
GO:0004950
P51681(UniProtKB)
TAS
GO:0005515
P51681(UniProtKB)
IPI
GO:0005515
P51681(UniProtKB)
IPI
GO:0005515
P51681(UniProtKB)
IPI
GO:0005515
P51681(UniProtKB)
IPI
GO:0005515
P51681(UniProtKB)
IPI
GO:0005515
P51681(UniProtKB)
IPI
GO:0005515
P51681(UniProtKB)
IPI
GO:0005737
P51681(UniProtKB)
TAS
GO:0005768
P51681(UniProtKB)
IDA
GO:0005886
P51681(UniProtKB)
TAS
GO:0005886
P51681(UniProtKB)
TAS
GO:0005886
P51681(UniProtKB)
TAS
GO:0005886
P51681(UniProtKB)
TAS
GO:0005886
P51681(UniProtKB)
TAS
GO:0005886
P51681(UniProtKB)
TAS
GO:0005886
P51681(UniProtKB)
TAS
GO:0005886
P51681(UniProtKB)
TAS
GO:0005886
P51681(UniProtKB)
TAS
GO:0005886
P51681(UniProtKB)
TAS
GO:0005887
P51681(UniProtKB)
TAS
GO:0006816
P51681(UniProtKB)
IDA
GO:0006935
P51681(UniProtKB)
TAS
GO:0006954
P51681(UniProtKB)
IEA
GO:0006955
P51681(UniProtKB)
IEA
GO:0006968
P51681(UniProtKB)
TAS
GO:0007166
P51681(UniProtKB)
TAS
GO:0007186
P51681(UniProtKB)
IMP
GO:0007204
P51681(UniProtKB)
TAS
GO:0007267
P51681(UniProtKB)
IDA
GO:0009897
P51681(UniProtKB)
IDA
GO:0009897
P51681(UniProtKB)
IDA
GO:0009897
P51681(UniProtKB)
IDA
GO:0009986
P51681(UniProtKB)
IDA
GO:0014808
P51681(UniProtKB)
IDA
GO:0015026
P51681(UniProtKB)
TAS
GO:0016493
P51681(UniProtKB)
IDA
GO:0016493
P51681(UniProtKB)
NAS
GO:0019064
P51681(UniProtKB)
TAS
GO:0019722
P51681(UniProtKB)
IDA
GO:0019722
P51681(UniProtKB)
IDA
GO:0019957
P51681(UniProtKB)
IPI
GO:0019957
P51681(UniProtKB)
IPI
GO:0019957
P51681(UniProtKB)
IPI
GO:0019957
P51681(UniProtKB)
IPI
GO:0019957
P51681(UniProtKB)
IPI
GO:0023052
P51681(UniProtKB)
IEP
GO:0030260
P51681(UniProtKB)
TAS
GO:0070098
P51681(UniProtKB)
IEA
GO:0070098
P51681(UniProtKB)
IEA
GO:0070723
P51681(UniProtKB)
IMP
GO:0071222
P51681(UniProtKB)
IEP
GO:0071791
P51681(UniProtKB)
IPI
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控CCR5基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
HIV Infections 0.184519152 861 4 BeFree_GAD_LHGDN
Hepatitis C 0.158739038 24 0 BeFree_CTD_human_GAD_LHGDN
IGA Glomerulonephritis 0.130725648 3 0 BeFree_CTD_human_GAD_LHGDN
West Nile Fever 0.124734064 2 0 CTD_human_GAD
Dermatitis, Atopic 0.12 1 0 CTD_human
Nephritis 0.12 1 0 CTD_human
Acute kidney injury 0.12 1 0 CTD_human
DIABETES MELLITUS, INSULIN-DEPENDENT, 22 (disorder) 0.12 0 0 CTD_human
Inflammation 0.10367032 11 0 GAD_RGD
Diabetes Mellitus, Insulin-Dependent 0.101922116 14 0 BeFree_GAD_RGD
Diabetes Mellitus, Non-Insulin-Dependent 0.096645169 15 0 BeFree_GAD_RGD
Kidney Failure, Chronic 0.096188161 8 0 BeFree_GAD_LHGDN_RGD
Alzheimer's Disease 0.089468128 5 0 GAD_RGD
Coronary Artery Disease 0.088458305 9 2 BeFree_GAD_RGD
Hypertensive disease 0.085276948 5 0 BeFree_GAD_RGD
Brain Ischemia 0.084734064 3 0 GAD_RGD
Uveitis 0.082367032 2 0 GAD_RGD
Experimental Autoimmune Encephalomyelitis 0.080542884 3 0 BeFree_RGD
Fever 0.08 1 0 RGD
Hyperalgesia 0.08 2 0 RGD
Myocardial Reperfusion Injury 0.08 1 0 RGD
Orchitis 0.08 1 0 RGD
Status Epilepticus 0.08 1 0 RGD
Anterior uveitis 0.08 1 0 RGD
Dermatitis, Allergic Contact 0.08 1 0 RGD
Hypoxia-Ischemia, Brain 0.08 1 0 RGD
Arthritis, Experimental 0.08 2 0 RGD
Infection 0.054487005 20 0 LHGDN
Multiple Sclerosis 0.05419875 28 0 BeFree_GAD_LHGDN
Acquired Immunodeficiency Syndrome 0.044568801 26 3 BeFree_GAD_LHGDN
Asthma 0.039205977 20 0 BeFree_GAD_LHGDN
Rheumatoid Arthritis 0.031985329 29 2 BeFree_GAD_LHGDN
Hepatitis C, Chronic 0.019098077 12 0 BeFree_GAD_LHGDN
Hepatitis B 0.017359805 11 0 BeFree_GAD_LHGDN
Diabetic Nephropathy 0.017002487 10 1 BeFree_GAD_LHGDN
Myocardial Infarction 0.013549688 8 1 BeFree_GAD_LHGDN
Graft-vs-Host Disease 0.013006804 5 0 BeFree_GAD_LHGDN
HIV disease progression 0.01183516 5 0 GAD
Atherosclerosis 0.011725539 8 0 BeFree_GAD_LHGDN
Mucocutaneous Lymph Node Syndrome 0.011182656 5 0 BeFree_GAD_LHGDN
Cardiovascular Diseases 0.010911214 5 0 BeFree_GAD_LHGDN
Viremia 0.010096888 5 0 BeFree_GAD_LHGDN
Hemophilia A 0.009544073 11 0 BeFree_GAD
Juvenile arthritis 0.009001189 7 0 BeFree_GAD
Lupus Nephritis 0.0089015 5 0 BeFree_GAD_LHGDN
Coronary heart disease 0.008815624 6 0 BeFree_GAD_LHGDN
Chagas Disease 0.008815624 5 0 BeFree_GAD_LHGDN
Cholangitis, Sclerosing 0.008544182 4 0 BeFree_GAD_LHGDN
Sarcoidosis 0.008544182 5 0 BeFree_GAD_LHGDN
Aortic Aneurysm, Abdominal 0.008001298 2 0 BeFree_GAD_LHGDN
Arterial Occlusive Diseases 0.007729856 2 0 BeFree_GAD_LHGDN
Sarcoidosis, Pulmonary 0.007729856 3 0 BeFree_GAD_LHGDN
Chlamydia Infections 0.007372538 3 0 BeFree_GAD
Pregnancy Complications, Infectious 0.007101096 3 0 GAD
Inflammatory Bowel Diseases 0.006905599 8 2 BeFree_GAD
Behcet Syndrome 0.00617715 4 0 BeFree_GAD_LHGDN
Coronary Arteriosclerosis 0.005819831 5 0 BeFree_GAD
Crohn Disease 0.005819831 4 0 BeFree_GAD
Chronic Obstructive Airway Disease 0.005634266 3 0 BeFree_GAD_LHGDN
Mammary Neoplasms 0.005634266 4 0 BeFree_GAD_LHGDN
Cervix carcinoma 0.00554839 3 0 BeFree_GAD
Adenocarcinoma 0.0054487 2 0 LHGDN
Prostatic Neoplasms 0.0054487 2 0 LHGDN
Brucellosis 0.005362824 1 0 BeFree_GAD_LHGDN
Schizophrenia 0.005362824 2 0 BeFree_GAD_LHGDN
Cerebrovascular accident 0.005276948 3 3 BeFree_GAD
melanoma 0.005091382 1 0 GAD_LHGDN
Disease Progression 0.005091382 2 0 GAD_LHGDN
Anemia, Sickle Cell 0.005005506 2 0 BeFree_GAD
Carotid Stenosis 0.005005506 2 0 BeFree_GAD
Chagas Cardiomyopathy 0.005005506 2 0 BeFree_GAD
Carotid Artery Diseases 0.004734064 2 0 GAD
Celiac Disease 0.004734064 2 1 GAD
Plague 0.004734064 2 0 GAD
Respiratory Syncytial Virus Infections 0.004734064 2 0 GAD
Substance Abuse, Intravenous 0.004734064 2 0 GAD
Bronchial Hyperreactivity 0.004734064 2 0 GAD
Hematologic Neoplasms 0.004734064 2 0 GAD
Hepatitis B, Chronic 0.004734064 2 0 GAD
Arthritis 0.004267125 7 0 BeFree_GAD
Malignant neoplasm of breast 0.004267125 7 0 BeFree_GAD
Virus Diseases 0.004071628 15 0 BeFree
Lupus Erythematosus, Systemic 0.003995683 6 0 BeFree_GAD
Malignant neoplasm of prostate 0.003995683 6 0 BeFree_GAD
Encephalitis 0.003810118 4 0 BeFree_LHGDN
Liver diseases 0.003538676 4 0 BeFree_LHGDN
Lichen Planus, Oral 0.003538676 3 0 BeFree_LHGDN
Liver carcinoma 0.003452799 4 0 BeFree_GAD
Multiple Myeloma 0.003267234 3 0 BeFree_LHGDN
Superinfection 0.003267234 3 0 BeFree_LHGDN
hiv-infection/aids 0.003257302 12 0 BeFree
Bronchiolitis 0.002995792 1 0 BeFree_LHGDN
Hyperlipidemia 0.002995792 1 0 BeFree_LHGDN
leukemia 0.002995792 2 0 BeFree_LHGDN
Lung diseases 0.002995792 2 0 BeFree_LHGDN
Myositis 0.002995792 2 0 BeFree_LHGDN
Vasculitis 0.002995792 2 0 BeFree_LHGDN
Renal Insufficiency 0.002995792 1 0 BeFree_LHGDN
Malignant neoplasm of urinary bladder 0.002909916 3 1 BeFree_GAD
Cytomegalovirus Infections 0.002909916 3 0 BeFree_GAD
Tick-Borne Encephalitis 0.002909916 3 2 BeFree_GAD
Liver Cirrhosis 0.002909916 2 0 BeFree_GAD
Lymphoma 0.002909916 3 0 BeFree_GAD
Periodontitis 0.002909916 2 0 BeFree_GAD
Arthritis, Reactive 0.002909916 2 0 BeFree_GAD
Malignant neoplasm of pancreas 0.002909916 2 0 BeFree_GAD
Pneumocystis jiroveci pneumonia 0.002909916 2 0 BeFree_GAD
Colorectal Neoplasms 0.00272435 1 0 LHGDN
Lymphocytic Choriomeningitis 0.00272435 1 0 LHGDN
Optic Neuritis 0.00272435 1 0 LHGDN
Arthritis, Psoriatic 0.002638474 1 0 BeFree_GAD
Transient Ischemic Attack 0.002638474 1 0 BeFree_GAD
Coronary Aneurysm 0.002638474 1 0 BeFree_GAD
Cryptosporidiosis 0.002638474 1 0 BeFree_GAD
Herpes zoster disease 0.002638474 1 0 BeFree_GAD
Meningoencephalitis 0.002638474 1 0 BeFree_GAD
Mycobacterium avium-intracellulare Infection 0.002638474 1 0 BeFree_GAD
Polymyalgia Rheumatica 0.002638474 2 0 BeFree_GAD
Toxoplasmosis 0.002638474 2 0 BeFree_GAD
Vitiligo 0.002638474 1 0 BeFree_GAD
Epstein-Barr Virus Infections 0.002638474 2 0 BeFree_GAD
Neoplasm, Residual 0.002638474 1 0 BeFree_GAD
Cancer of Head and Neck 0.002638474 1 0 BeFree_GAD
Mucocutaneous leishmaniasis 0.002638474 1 0 BeFree_GAD
Hemophilia, NOS 0.002442977 9 0 BeFree
Aortic Valve Stenosis 0.002367032 1 0 GAD
Berylliosis 0.002367032 1 0 GAD
Biliary Tract Diseases 0.002367032 1 0 GAD
Brain Neoplasms 0.002367032 1 0 GAD
Bronchiolitis, Viral 0.002367032 1 0 GAD
Chromosome Deletion 0.002367032 1 0 GAD
Cross Infection 0.002367032 1 0 GAD
Embolism 0.002367032 1 0 GAD
Erythema Nodosum 0.002367032 1 0 GAD
Female Genital Diseases 0.002367032 1 0 GAD
Delayed Hypersensitivity 0.002367032 1 0 GAD
Immediate hypersensitivity 0.002367032 1 0 GAD
Hypertension, Portal 0.002367032 1 0 GAD
Female infertility 0.002367032 1 0 GAD
Ischemia 0.002367032 1 0 GAD
Laryngeal neoplasm 0.002367032 1 0 GAD
Leishmaniasis, Cutaneous 0.002367032 1 0 GAD
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 0.002367032 1 0 GAD
Biliary cirrhosis 0.002367032 1 0 GAD
Liver neoplasms 0.002367032 1 0 GAD
Animal Mammary Neoplasms 0.002367032 1 0 GAD
Neoplasm Recurrence, Local 0.002367032 1 0 GAD
Nephrotic Syndrome 0.002367032 1 0 GAD
Occupational Diseases 0.002367032 1 0 GAD
Postoperative Complications 0.002367032 1 0 GAD
Rheumatism 0.002367032 1 0 GAD
Skin Neoplasms 0.002367032 1 0 GAD
Thyroid Neoplasm 0.002367032 1 0 GAD
Trachoma 0.002367032 1 0 GAD
Diffuse Large B-Cell Lymphoma 0.002367032 1 0 GAD
Left Ventricular Hypertrophy 0.002367032 1 0 GAD
Aneurysm, Ruptured 0.002367032 1 0 GAD
Renal transplant rejection 0.002367032 1 0 GAD
Malignant neoplasm of lung 0.002367032 1 0 GAD
Restenosis 0.002367032 1 0 GAD
Human immunodeficiency virus leukoencephalopathy 0.002367032 1 0 GAD
Pregnancy loss 0.002367032 1 0 GAD
Acute Coronary Syndrome 0.002367032 1 0 GAD
Coronary Restenosis 0.002367032 1 0 GAD
Systemic arterial pressure 0.002367032 1 0 GAD
Sjogren's Syndrome 0.002367032 1 0 GAD
Venous Thromboembolism 0.002367032 1 0 GAD
HIV-1 infection 0.002367032 1 0 GAD
Chronic ulcerative colitis 0.002367032 1 0 GAD
Granulomatosis with polyangiitis 0.002367032 1 0 GAD
Mitral Valve Stenosis 0.002171535 8 0 BeFree
Neoplasm Metastasis 0.002171535 8 0 BeFree
Juvenile rheumatoid arthritis 0.002171535 8 0 BeFree
Arteriosclerosis 0.001900093 7 0 BeFree
Breast Carcinoma 0.001900093 7 0 BeFree
Kidney Diseases 0.001628651 6 0 BeFree
Prostate carcinoma 0.001628651 6 0 BeFree
West Nile viral infection 0.001628651 6 0 BeFree
Colorectal Carcinoma 0.001357209 5 0 BeFree
Herpes Simplex Infections 0.001357209 5 0 BeFree
Tuberculosis, Pulmonary 0.001357209 5 0 BeFree
Primary infection NOS 0.001357209 5 0 BeFree
Colorectal Cancer 0.001357209 5 0 BeFree
Ulcerative Colitis 0.001085767 4 1 BeFree
Immunologic Deficiency Syndromes 0.001085767 4 0 BeFree
Influenza 0.001085767 4 0 BeFree
Kidney Failure 0.001085767 4 0 BeFree
Tuberculosis 0.001085767 4 0 BeFree
Chronic kidney disease stage 5 0.001085767 4 2 BeFree
AIDS Dementia Complex 0.000814326 3 0 BeFree
Malignant tumor of cervix 0.000814326 3 0 BeFree
Glioblastoma 0.000814326 3 0 BeFree
Malaria 0.000814326 3 0 BeFree
Degenerative polyarthritis 0.000814326 3 0 BeFree
Giant Cell Arteritis 0.000814326 3 0 BeFree
Malignant neoplasm of mouth 0.000814326 3 0 BeFree
Lip and Oral Cavity Carcinoma 0.000814326 3 0 BeFree
Human immunodeficiency virus, type 2 [HIV-2] infection in conditions classified elsewhere and of unspecified site 0.000814326 3 0 BeFree
Primary sclerosing cholangitis 0.000814326 3 0 BeFree
Cardiomyopathies 0.000814326 3 0 BeFree
Astrocytoma 0.000542884 2 0 BeFree
Primary biliary cirrhosis 0.000542884 2 0 BeFree
Dengue Fever 0.000542884 2 0 BeFree
Diabetes 0.000542884 2 0 BeFree
Diabetes Mellitus 0.000542884 2 0 BeFree
Heart failure 0.000542884 2 0 BeFree
Congestive heart failure 0.000542884 2 0 BeFree
Leishmaniasis 0.000542884 2 0 BeFree
nervous system disorder 0.000542884 2 0 BeFree
Obesity 0.000542884 2 0 BeFree
Opportunistic Infections 0.000542884 2 0 BeFree
Psoriasis 0.000542884 2 0 BeFree
Vascular Diseases 0.000542884 2 0 BeFree
Severe Combined Immunodeficiency 0.000542884 2 0 BeFree
Active tuberculosis 0.000542884 2 0 BeFree
Primary Sj�gren's syndrome 0.000542884 2 0 BeFree
Allergic asthma 0.000542884 2 0 BeFree
Tumor Progression 0.000542884 2 0 BeFree
Pancreatic carcinoma 0.000542884 2 0 BeFree
Coinfection 0.000542884 2 0 BeFree
Bubonic Plague 0.000542884 2 0 BeFree
Superficial ulcer 0.000542884 2 0 BeFree
Infective vaginitis 0.000542884 2 0 BeFree
Granulomatosis 0.000542884 2 0 BeFree
Metabolic Syndrome X 0.000542884 2 0 BeFree
Carcinoma of bladder 0.000542884 2 1 BeFree
Bone Diseases 0.000271442 1 0 BeFree
Malignant tumor of colon 0.000271442 1 0 BeFree
CNS disorder 0.000271442 1 0 BeFree
Chondrosarcoma 0.000271442 1 0 BeFree
Choriocarcinoma 0.000271442 1 0 BeFree
Cystic Fibrosis 0.000271442 1 0 BeFree
Presenile dementia 0.000271442 1 0 BeFree
Down Syndrome 0.000271442 1 0 BeFree
Dry Eye Syndromes 0.000271442 1 0 BeFree
Endometriosis 0.000271442 1 1 BeFree
Gaucher Disease 0.000271442 1 0 BeFree
Gingival Diseases 0.000271442 1 0 BeFree
Glioma 0.000271442 1 0 BeFree
Graves Disease 0.000271442 1 0 BeFree
Hodgkin Disease 0.000271442 1 0 BeFree
Arthropathy 0.000271442 1 0 BeFree
Acute Kidney Tubular Necrosis 0.000271442 1 0 BeFree
Leukemia, Myelocytic, Acute 0.000271442 1 0 BeFree
Lymphoma, Follicular 0.000271442 1 0 BeFree
Measles 0.000271442 1 0 BeFree
Mouth Neoplasms 0.000271442 1 0 BeFree
Mycoses 0.000271442 1 0 BeFree
Nephritis, Interstitial 0.000271442 1 0 BeFree
Neuroblastoma 0.000271442 1 0 BeFree
Osteomyelitis 0.000271442 1 0 BeFree
Osteosarcoma 0.000271442 1 0 BeFree
Pancreatic Neoplasm 0.000271442 1 0 BeFree
Periodontal Diseases 0.000271442 1 0 BeFree
Pulmonary Edema 0.000271442 1 0 BeFree
Retinal Detachment 0.000271442 1 0 BeFree
Sexually Transmitted Diseases 0.000271442 1 0 BeFree
Smallpox 0.000271442 1 0 BeFree
Synovitis 0.000271442 1 0 BeFree
Syphilis 0.000271442 1 0 BeFree
Tetanus 0.000271442 1 0 BeFree
Yellow Fever 0.000271442 1 0 BeFree
Lymphoma, AIDS-Related 0.000271442 1 0 BeFree
Acute leukemia 0.000271442 1 0 BeFree
Genital ulceration 0.000271442 1 0 BeFree
Adenocarcinoma of lung (disorder) 0.000271442 1 0 BeFree
Joint swelling 0.000271442 1 0 BeFree
Idiopathic pulmonary hypertension 0.000271442 1 0 BeFree
Systemic candidiasis 0.000271442 1 0 BeFree
Secondary malignant neoplasm of lung 0.000271442 1 0 BeFree
Secondary malignant neoplasm of bone 0.000271442 1 0 BeFree
Infections specific to perinatal period 0.000271442 1 0 BeFree
Chronic berylliosis 0.000271442 1 0 BeFree
Morning stiffness (>1 hour) 0.000271442 1 0 BeFree
pediatric AIDS 0.000271442 1 0 BeFree
Mucosa-Associated Lymphoid Tissue Lymphoma 0.000271442 1 0 BeFree
Parasitemia 0.000271442 1 0 BeFree
Ichthyosis linearis circumflexa 0.000271442 1 0 BeFree
Vesicular Stomatitis 0.000271442 1 0 BeFree
Metastatic melanoma 0.000271442 1 0 BeFree
Adenocarcinoma of pancreas 0.000271442 1 0 BeFree
Rocio virus encephalitis 0.000271442 1 0 BeFree
Chronic liver disease 0.000271442 1 0 BeFree
Asymptomatic human immunodeficiency virus infection 0.000271442 1 0 BeFree
Disseminated Malignant Neoplasm 0.000271442 1 0 BeFree
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site 0.000271442 1 0 BeFree
Idiopathic crescentic glomerulonephritis 0.000271442 1 0 BeFree
Neuropathy 0.000271442 1 0 BeFree
Dementia 0.000271442 1 0 BeFree
Osteosarcoma of bone 0.000271442 1 0 BeFree
Biliary stricture 0.000271442 1 0 BeFree
Terminal illness 0.000271442 1 0 BeFree
Colon Carcinoma 0.000271442 1 0 BeFree
Central neuroblastoma 0.000271442 1 0 BeFree
AIDS defining illness 0.000271442 1 0 BeFree
infertility tubal factor 0.000271442 1 0 BeFree
lung disease granulomatous 0.000271442 1 0 BeFree
Acute GVH disease 0.000271442 1 0 BeFree
Metastatic Prostate Carcinoma 0.000271442 1 0 BeFree
Colorectal cancer metastatic 0.000271442 1 0 BeFree
Primary HIV infection 0.000271442 1 0 BeFree
Squamous cell carcinoma of the head and neck 0.000271442 1 0 BeFree
Inflammatory disorder 0.000271442 1 0 BeFree
Aggressive natural killer-cell leukemia 0.000271442 1 0 BeFree
Peripheral arterial occlusive disease 0.000271442 1 0 BeFree
Pediatric human immunodeficiency virus infection 0.000271442 1 0 BeFree
Neuropathogenesis 0.000271442 1 0 BeFree
Tumor Angiogenesis 0.000271442 1 0 BeFree
Ocular surface disease 0.000271442 1 0 BeFree
Non-Malignant Ascites Adverse Event 0.000271442 1 0 BeFree
Upper urinary tract infection 0.000271442 1 0 BeFree
MULTICYSTIC RENAL DYSPLASIA, BILATERAL 0.000271442 1 0 BeFree
Pulmonary arterial hypertension 0.000271442 1 0 BeFree
Pulmonary Hypertension, Primary, 1, With Hereditary Hemorrhagic Telangiectasia 0.000271442 1 0 BeFree
Flaviviral diseases 0.000271442 1 0 BeFree
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