C21orf2基因详情-基因数据库-基因云馆

C21orf2(chromosome 21 open reading frame 2)

基因简称(symbol)

C21orf2 [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

YF5|A2|LRRC76

基因家族代码(gene_family_id)

[HGNC] [GenScript]

omim代码

603191

entrez码

755 [Vega]

vega基因码

OTTHUMG00000086909

ensembl基因码

ENSG00000160226 [Ensembl]

基因家族(gene family)

refseq数据库代号

NM_004928

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

21q22.3

同源基因名称(alias name)

nuclear encoded mitochondrial protein|leucine rich repeat containing 76

基因名称批准使用时间(date_approved_reserved)

1998-08-06T00:00:00Z

基因简称更名时间(date_symbol_changed)

基因名称更名时间(date_name_changed)

更新时间(date_modified)

2014-11-19T00:00:00Z

ucsc码

uc002zeq.2

ena

Y11392

ccds数据码

CCDS13709|CCDS59444|CCDS59445

uniprot数据码

O43822

pubmed代码

9465297

mgd码

MGI:1915134

rgd码

RGD:1309594

生命科学数据库(lsdb)

更新时间(date modified)

2014-11-19T00:00:00Z

cosmic

C21orf2

mirbase

基因曾用简称(prev symbol)

基因曾用名称(prev name)

homeodb

cosmic

C21orf2

snornabase

bioparadigms slc

orphanet

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

21q22.3

Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients. [provided by RefSeq, Sep 2012]

[中文简述(自动翻译):] 福选择性剪接转录变异体的编码四种不同的亚型已经发现这个核基因。所有亚型含有丰富的亮氨酸重复。这些同种型中的三个是线粒体蛋白，其中之一缺少靶肽，所以不位于线粒体。唐氏综合症（DS）的脑，其可以在DS中的患者代表的线粒体功能障碍该基因下调。 [由RefSeq的，2012年9月提供]

OMIM数据库中对C21orf2基因的介绍 Wikipedia数据库中对C21orf2基因的介绍

C21orf2基因的碱基序列：[NCBI]

C21orf2基因的碱基突变：显示全部snp

rs11870 rs14313 rs1056687 rs1056689 rs1056725 rs2070572 rs2070573 rs2236441 rs2277809 rs3761392 rs3761393 rs3788121 rs4818709 rs4818710 rs9306098 rs9306099 rs9974319 rs9976610 rs9977790 rs9981135 rs9984787 rs10470254 rs11552066 rs11552067 rs11552068 rs11909668 rs11910721 rs35498868 rs56212056 rs56242109 rs56825465 rs57088924 rs57125046 rs57369444 rs57970143 rs57981678 rs58670754

rs59125000 rs59596996 rs59720734 rs60027384 rs60110149 rs60345888 rs60469495 rs60835285 rs61734070 rs62000360 rs62220411 rs62220412 rs62220413 rs66904159 rs66916924 rs71197893 rs71326048 rs73231264 rs73231265 rs73374009 rs73374018 rs73374021 rs73374031 rs73907165 rs73907166 rs73907168 rs73907169 rs73907170 rs73907171 rs73907172 rs73907173 rs73907174 rs73907175 rs74354449 rs75078480 rs75087725 rs75103871 rs75183230 rs75584847 rs75733226 rs76435115 rs76447640 rs76523845 rs76736548 rs77610661 rs77970521 rs78093409 rs78197894 rs78221065 rs78439236 rs78502891 rs78738212 rs79299307 rs79389074 rs79797717 rs80044832 rs80060465 rs111119177 rs111434965 rs111631573 rs111711465 rs111784759 rs111950923 rs112247441 rs112370650 rs112436478 rs112453644 rs112926736 rs113140347 rs113602050 rs113983126 rs114054360 rs114140671 rs114344169 rs114583726 rs114642139 rs114782596 rs114995914 rs115007048 rs115171187 rs115209401 rs115486108 rs115495245 rs115529052 rs115608642 rs115857899 rs116088022 rs116171340 rs116737357 rs116803249 rs117840172 rs118187037 rs138100132 rs138201782 rs138214126 rs138755532 rs138876778 rs139038672 rs139067933 rs139118601 rs139131768 rs139328963 rs139415625 rs139797762 rs140181378 rs140217573 rs140378076 rs140416683 rs140451304 rs140886820 rs141195315 rs141427556 rs141744017 rs141911691 rs142069255 rs142252957 rs142280076 rs142311165 rs142691279 rs142932867 rs143125960 rs143553150 rs143659446 rs144423451 rs144430869 rs144775318 rs145039152 rs145099593 rs145211781 rs145523761 rs145799186 rs146104157 rs146136508 rs146343338 rs146383659 rs146435118 rs146439348 rs146462028 rs146572662 rs147159770 rs147363817 rs147594889 rs147624402 rs147855042 rs148023924 rs148111961 rs148164509 rs148255412 rs148425324 rs148553252 rs148867563 rs149158582 rs149244254 rs149386620 rs149601648 rs149699846 rs150368688 rs151158764 rs151236255 rs180980740 rs181149547 rs181692122 rs181828659 rs181944855 rs182132626 rs182189357 rs182333890 rs182451977 rs183079367 rs183183590 rs183220986 rs183246225 rs183595358 rs184046038 rs184288061 rs184756537 rs184911649 rs184983423 rs185538642 rs185842266 rs185961242 rs186382635 rs186540315 rs186689436 rs186780161 rs187741004 rs188086777 rs188312067 rs188379680 rs188380965 rs188447507 rs188536480 rs188852613 rs189162062 rs189695721 rs190631641 rs190790356 rs190832779 rs191396016 rs191492655 rs191498562 rs191679630 rs192125415 rs192362496 rs192417075 rs192429995 rs192858930 rs192880944 rs200038076 rs200049699 rs200411422 rs200748945 rs201127621 rs201278533 rs201329990 rs201576990 rs201598607 rs201945353 rs202065452 rs202196237 rs367700780 rs367740530 rs367870033 rs368079632 rs368095791 rs368147617 rs368422588 rs368674927 rs368748781 rs368928576 rs368976859 rs369039466 rs369370304 rs369493459 rs369844038 rs369935156 rs370075444 rs370295137 rs370429852 rs371211181 rs371653272 rs372118549 rs372186065 rs372282046 rs372506033 rs372541349 rs372614395 rs372721170 rs372853354 rs372854948 rs372992486 rs373035903 rs373313608 rs373517822 rs373854808 rs374507502 rs374549037 rs374674790 rs374859132 rs375087550 rs375476483 rs375671585 rs375698855 rs376235939 rs376270382 rs376322324 rs376509584 rs377185498 rs377441507 rs377552361 rs377579876 rs377640840 rs377650325 rs527366002 rs527882087 rs527883972 rs527918461 rs528067846 rs528141122 rs528395184 rs528429254 rs528601860 rs529091604 rs529208649 rs529274041 rs529300829 rs529440911 rs529604788 rs529643120 rs530304779 rs530522045 rs530569964 rs530667565 rs530728785 rs530847500 rs530851137 rs531007110 rs531036991 rs531044180 rs531395614 rs531883168 rs531979406 rs532057055 rs532209002 rs532608064 rs533084696 rs533151512 rs533156525 rs533224231 rs533260914 rs533273002 rs533465673 rs533721512 rs534078276 rs534166281 rs534384075 rs534417058 rs534478718 rs534722715 rs534873647 rs535030287 rs535319791 rs535581098 rs535714713 rs535744249 rs535833529 rs536187631 rs536433942 rs536546232 rs536630584 rs536876713 rs537034772 rs537113160 rs537223521 rs537644994 rs537714564 rs537750706 rs538229905 rs538357108 rs538509516 rs538804546 rs538994908 rs539049448 rs539517944 rs539717393 rs539817137 rs539866392 rs540184135 rs540246599 rs540247780 rs540687934 rs540688180 rs541046913 rs541605607 rs541764625 rs541905436 rs542277809 rs542467311 rs542861021 rs542989343 rs543098757 rs543148803 rs543713331 rs543783476 rs544170863 rs544609532 rs544679642 rs544718455 rs544855045 rs544978124 rs545183540 rs545343167 rs545542893 rs545801451 rs545877103 rs545968475 rs546213819 rs546263553 rs546287894 rs546323045 rs546399932 rs546449413 rs546739223 rs546887987 rs547426925 rs547517126 rs547610646 rs547713142 rs547750263 rs547751923 rs547791227 rs548029378 rs548224789 rs548703847 rs548723906 rs548821694 rs549021833 rs549163272 rs549965260 rs550016453 rs550034375 rs550078481 rs550302984 rs550402758 rs550556443 rs550911937 rs551022281 rs551102398 rs551173660 rs551337364 rs551500220 rs551535751 rs551678373 rs551692194 rs551740814 rs552418307 rs552686031 rs552792461 rs552827983 rs552856457 rs552942543 rs553161917 rs553241880 rs553278564 rs553545644 rs553818195 rs554033309 rs554105334 rs554355758 rs554429309 rs554477823 rs554677613 rs554961895 rs555164150 rs555204989 rs555277017 rs555296233 rs555860989 rs555958939 rs556301101 rs556648162 rs556849578 rs556886142 rs557082104 rs557148585 rs557362272 rs557666495 rs557869645 rs557916604 rs558035641 rs558451821 rs558603286 rs559004843 rs559007032 rs559082761 rs559122169 rs559245598 rs559286002 rs559322180 rs559324166 rs559366777 rs559477335 rs559588631 rs559608911 rs560182161 rs561098091 rs561310243 rs561344830 rs561826842 rs562026804 rs562161603 rs562350888 rs562586179 rs562997670 rs563028044 rs563469841 rs563535881 rs563632372 rs565142962 rs565380193 rs565406080 rs565701199 rs565722562 rs565722595 rs565960183 rs566367905 rs566824024 rs566886225 rs566909943 rs566910188 rs566953201 rs567017370 rs567227749 rs567435284 rs567559896 rs568122319 rs568213321 rs568293129 rs568410064 rs568449502 rs568642343 rs568842895 rs569193294 rs569395314 rs569592565 rs569595935 rs569678037 rs569797617 rs569949897 rs570512504 rs570743865 rs570783280 rs570903903 rs571139938 rs571862837 rs571989278 rs572026656 rs572283576 rs572496930 rs572707626 rs572779889 rs572947409 rs573147862 rs573229850 rs573366125 rs573655806 rs574007967 rs574100879 rs574215463 rs574436763 rs574536760 rs574859845 rs575094062 rs575300671 rs575392770 rs575547314 rs575555871 rs575660019 rs576111001 rs576560435 rs576589166 rs576594959 rs576614689 rs576749058 rs576796801 rs576853928 rs577267289 rs577416110 rs577434910 rs577770193 rs577795304 rs577858726 rs577943136 rs577995881 rs745393870 rs745430992 rs745656075 rs745732992 rs745920377 rs746027663 rs746114248 rs746114465 rs746367846 rs746389197 rs746473908 rs746594475 rs746633371 rs746806560 rs746856287 rs746909341 rs747034539 rs747087043 rs747205833 rs747351700 rs747669435 rs747734523 rs747760478 rs747917720 rs748118167 rs748224537 rs748438502 rs748728864 rs748809757 rs748897535 rs748929175 rs749095874 rs749261239 rs749459116 rs749594754 rs749720437 rs749770540 rs749801652 rs749857385 rs749911433 rs749951234 rs750020087 rs750105410 rs750215095 rs750472057 rs750561784 rs750561947 rs750677461 rs750760441 rs750809604 rs750956343 rs751035924 rs751123948 rs751163294 rs751274493 rs751468650 rs751730336 rs751833333 rs751835614 rs752031315 rs752137434 rs752177640 rs752269920 rs752399030 rs752399565 rs752479202 rs752595167 rs752657657 rs752683561 rs752698486 rs752866263 rs752983573 rs753175912 rs753752452 rs753781658 rs753882358 rs753923627 rs754027698 rs754188529 rs754351767 rs754626994 rs754823280 rs754854788 rs755005560 rs755022406 rs755186566 rs755424242 rs755462234 rs755475533 rs755636803 rs755673924 rs755764030 rs755945783 rs755996355 rs756182350 rs756184388 rs756429410 rs756596432 rs756627311 rs756791423 rs757097265 rs757142399 rs757262220 rs757336439 rs757494319 rs757586462 rs757638302 rs757692946 rs757746970 rs757891132 rs758011352 rs758224762 rs758235839 rs758259141 rs758391072 rs758407596 rs758738754 rs758835278 rs759215341 rs759300468 rs759420488 rs759456714 rs759614818 rs759653337 rs759722433 rs759884906 rs760073135 rs760097234 rs760747981 rs760836045 rs760843025 rs761053125 rs761501026 rs761779834 rs761885432 rs762159564 rs762237699 rs762701847 rs762837824 rs762884270 rs762918001 rs763115707 rs763283803 rs763307422 rs763314924 rs763623409 rs763624843 rs763821454 rs763885757 rs764177807 rs764188617 rs764389236 rs764440766 rs764481128 rs764554346 rs764585362 rs764771819 rs764957477 rs765036174 rs765058590 rs765226708 rs765281610 rs765602433 rs765740480 rs765804475 rs765936698 rs766177483 rs766338501 rs766422381 rs766585233 rs766589815 rs766874630 rs767299159 rs767314535 rs767420984 rs767560634 rs767710537 rs767756871 rs767796576 rs767817825 rs767869403 rs767953846 rs768252634 rs768524759 rs768576190 rs768599683 rs768720660 rs769014966 rs769070783 rs769078005 rs769441679 rs769483508 rs769743215 rs769824575 rs770018578 rs770051211 rs770389083 rs770527377 rs770527417 rs770586074 rs770721510 rs770840314 rs771024688 rs771051593 rs771112528 rs771203756 rs771486173 rs771681892 rs771874335 rs772092677 rs772290599 rs772426107 rs772718835 rs772736437 rs772829403 rs773037448 rs773145451 rs773361360 rs773375363 rs773463440 rs773592228 rs773849527 rs773854721 rs773872732 rs773942752 rs774096260 rs774181788 rs774426087 rs774614339 rs774640383 rs774723827 rs774917924 rs774927073 rs775012349 rs775094657 rs775288740 rs775300297 rs775410911 rs775483146 rs775496851 rs775656734 rs775668894 rs775761530 rs775786500 rs775874474 rs775984914 rs776093460 rs776236382 rs776435899 rs776518429 rs776633338 rs777176712 rs777360918 rs777397625 rs777478813 rs777514004 rs777556387 rs777590542 rs777749209 rs777832348 rs777946402 rs778222701 rs778317077 rs778325930 rs778534124 rs778791287 rs778880876 rs778986381 rs778987436 rs779185167 rs779288110 rs779365569 rs779366620 rs779372374 rs779474015 rs779571401 rs779793849 rs780027455 rs780241928 rs780412319 rs780617907 rs780705668 rs780887106 rs780892823 rs781366937 rs781390226 rs781636130 rs781706677 rs781717655 rs781762035

C21orf2基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

GCCTCACAGATTAGAGATGG

58

AATACTTTGCGAGGCTGAG

58

TCACAGATATCTCCATTTGCCA

60

TATGTCACAGTGCTGGGTC

59

CTCACAGATATCTCCATTTGCC

59

CAGGTACAGCTCACTCAGG

60

CCTCACAGATTAGAGATGGAG

57

AATACTTTGCGAGGCTGAG

58

CTACAGAAGCTGGACAACC

58

TCTCCTCTCCCTCACTCAG

59

TCACAGATATCTCCATTTGCCA

60

CAGGTACAGCTCACTCAGG

60

TACAGAAGCTGGACAACCAG

60

TCTCCTCTCCCTCACTCAG

59

CAAGCTATGCTGCACACTG

60

CTGAGAGGGAAGGAAACTGG

60

GAGATGCCTGTCTACACCA

59

TAGAACCTCCAGACCACAG

58

GCCTCACAGATTAGAGATGGA

59

ATACTTTGCGAGGCTGAGG

60

尚未收录相关数据

C21orf2基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

C21orf2基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0003674

O43822(UniProtKB)

ND

GO:0005515

O43822(UniProtKB)

IPI

GO:0005515

O43822(UniProtKB)

IPI

GO:0005737

O43822(UniProtKB)

IDA

GO:0005739

O43822(UniProtKB)

IDA

GO:0005886

O43822(UniProtKB)

IDA

GO:0007010

O43822(UniProtKB)

IMP

GO:0007224

O43822(UniProtKB)

IEA

GO:0008360

O43822(UniProtKB)

IMP

GO:0032391

O43822(UniProtKB)

ISS

GO:0060271

O43822(UniProtKB)

IEA

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控C21orf2基因的相关microRNA：

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Down Syndrome	0.003267234	2	0	BeFree_LHGDN
Alzheimer's Disease	0.00272435	1	0	LHGDN
Friedreich Ataxia	0.000542884	2	0	BeFree
Cardiomyopathies	0.000542884	2	0	BeFree
Polyglandular Type I Autoimmune Syndrome	0.000271442	1	0	BeFree
Hearing Loss, Mixed Conductive-Sensorineural	0.000271442	1	0	BeFree
Mitochondrial Myopathies	0.000271442	1	0	BeFree
Jeune thoracic dystrophy	0.000271442	1	0	BeFree
Nonsyndromic Deafness	0.000271442	1	0	BeFree