GAST(gastrin) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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17q21.2
基因染色体位置图

Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  胃泌素是一种激素,其主要功能是由胃粘膜,这导致胃泌素形成的抑制,刺激盐酸分泌。这种激素也充当胃肠上皮细胞促有丝分裂因子。胃泌素具有两个生物活性肽的形式,G34和G17。 [由RefSeq的,2008年7月提供]

GAST基因的碱基序列:[NCBI]
GAST基因的碱基突变:           显示全部snp
rs4290525       rs4796684       rs5014485       rs7209476       rs7210961       rs7216342       rs7217121       rs7219024       rs7219043       rs7219746       rs7220169       rs7223299       rs7223596       rs7225040       rs8065027       rs8072862       rs9889551       rs9893571       rs9906520       rs9913713       rs9914474       rs9915474       rs11286851       rs11652776       rs11658099       rs11658100       rs12453761       rs28627048       rs34074411       rs34309618       rs34997578       rs57469188       rs57593093       rs71155161       rs71272907       rs71357514       rs71357515      
rs72833780       rs74347421       rs74643658       rs74740060       rs76604302       rs79715822       rs111304033       rs111463513       rs112271257       rs112774254       rs113579268       rs114096257       rs117292940       rs138073636       rs138181919       rs138231893       rs138601174       rs139403346       rs139507904       rs139785775       rs140105651       rs140471035       rs140534794       rs140947135       rs141052751       rs141323754       rs141697465       rs142805597       rs142855136       rs142911497       rs143414066       rs143810734       rs143873241       rs144173344       rs144507633       rs144655796       rs144731510       rs145246914       rs145661794       rs145668029       rs145765054       rs146876535       rs146879787       rs147436243       rs148116866       rs148650058       rs149172957       rs149262622       rs149304568       rs149536370       rs150206234       rs150575514       rs151026885       rs151099286       rs180684212       rs181275629       rs181362453       rs181557686       rs182007698       rs182636702       rs182895845       rs183346277       rs184678095       rs184848494       rs184852708       rs185340961       rs185448463       rs186387700       rs187094896       rs187563281       rs187626084       rs187627361       rs188070181       rs189013727       rs189055410       rs189092635       rs189310845       rs189714385       rs190449297       rs191589667       rs192045308       rs192459134       rs192917710       rs193085139       rs200278472       rs200691368       rs200728651       rs200971654       rs201414566       rs202173406       rs202238440       rs368128759       rs368171343       rs369743329       rs370349440       rs370408695       rs370740466       rs371054978       rs371500519       rs372946766       rs373599038       rs373690208       rs375546672       rs375699677       rs377220004       rs527936469       rs528239057       rs528276264       rs528920506       rs528957276       rs529529227       rs530174780       rs530585753       rs531834125       rs532180744       rs532313920       rs532576728       rs532680260       rs532919672       rs533986934       rs534072749       rs534128451       rs534303188       rs535385347       rs535647893       rs535991178       rs536193130       rs536620597       rs537090635       rs537646337       rs538390243       rs538991372       rs539616173       rs539694887       rs540027739       rs540365709       rs540961107       rs542334863       rs542950388       rs544124392       rs544164304       rs544612443       rs546271311       rs546311868       rs546570490       rs547151182       rs547287321       rs547331291       rs547909345       rs547954700       rs548077000       rs550261565       rs550304362       rs550406204       rs551846521       rs553146191       rs553474729       rs553727661       rs555417825       rs555498041       rs555641004       rs556006540       rs556241609       rs557241903       rs557434029       rs557632334       rs558018754       rs558028337       rs558038397       rs558247405       rs559189062       rs559232501       rs559753937       rs559850211       rs561733639       rs562152710       rs563621207       rs564189788       rs564209196       rs565834522       rs566057614       rs566070996       rs566788656       rs567456188       rs567522198       rs568057963       rs568092965       rs570450689       rs571342258       rs571687582       rs571727163       rs573092407       rs573128505       rs573788878       rs573876197       rs574585561       rs575117294       rs575610760       rs575821000       rs576636817       rs577528663       rs577565280       rs577618939       rs577970447       rs781790503       rs781883642       rs781901913       rs781902893       rs781950209       rs781950455       rs781969648       rs781969842       rs781978713       rs781979891       rs781994438       rs782023925       rs782049514       rs782056767       rs782085786       rs782135575       rs782159860       rs782167531       rs782170362       rs782188604       rs782211173       rs782224974       rs782280205       rs782304560       rs782313597       rs782345532       rs782357713       rs782386796       rs782422797       rs782437955       rs782468119       rs782469519       rs782478288       rs782557458       rs782576189       rs782594228       rs782644590       rs782645115       rs782652898       rs782672889       rs782675998       rs782714381       rs782742739       rs782745910       rs782763780       rs782782523       rs782797563      

GAST基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CCTCTCATCATCGAAGGCA
59
TTCTCATCCTCAGCACTGC
60
CTCTCATCATCGAAGGCAG
58
GTTCTCATCCTCAGCACTG
58
CCTCTCATCATCGAAGGCA
59
GTTCTCATCCTCAGCACTG
58
      尚未收录相关数据

GAST基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

GAST基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0005179
P01350(UniProtKB)
IEA
GO:0005515
P01350(UniProtKB)
IPI
GO:0005576
P01350(UniProtKB)
TAS
GO:0005576
P01350(UniProtKB)
TAS
GO:0005576
P01350(UniProtKB)
TAS
GO:0005576
P01350(UniProtKB)
TAS
GO:0005615
P01350(UniProtKB)
IBA
GO:0007165
P01350(UniProtKB)
NAS
GO:0007186
P01350(UniProtKB)
IBA
GO:0032094
P01350(UniProtKB)
IBA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控GAST基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Stomach Neoplasms 0.126263026 5 0 BeFree_CTD_human_LHGDN
Adenocarcinoma 0.124895885 10 0 BeFree_CTD_human_LHGDN
Colonic Neoplasms 0.123267234 4 0 BeFree_CTD_human_LHGDN
Lung Neoplasms 0.12272435 2 0 CTD_human_LHGDN
Peptic Ulcer 0.120542884 3 0 BeFree_CTD_human
Barrett Esophagus 0.12 1 0 CTD_human
Gastrointestinal Diseases 0.12 1 0 CTD_human
Reperfusion Injury 0.12 1 0 CTD_human
Stomach Carcinoma 0.009500466 35 0 BeFree
Colorectal Neoplasms 0.008715934 5 0 BeFree_LHGDN
Malignant neoplasm of stomach 0.00868614 32 0 BeFree
Malignant tumor of colon 0.005700279 21 0 BeFree
Colon Carcinoma 0.005700279 21 0 BeFree
Metaplasia 0.0054487 2 0 LHGDN
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site 0.005157396 19 0 BeFree
Carcinogenesis 0.005157396 19 0 BeFree
Gastrinoma 0.004614512 17 0 BeFree
Zollinger-Ellison syndrome 0.004353001 6 0 BeFree_LHGDN
Colorectal Carcinoma 0.004071628 15 0 BeFree
Colorectal Cancer 0.004071628 15 0 BeFree
Pancreatic carcinoma 0.003257302 12 0 BeFree
Malignant neoplasm of pancreas 0.003257302 12 0 BeFree
Hemochromatosis 0.002995792 1 0 BeFree_LHGDN
Carcinoid Tumor 0.002985861 11 0 BeFree
Biliary Tract Neoplasm 0.00272435 1 0 LHGDN
Inflammation 0.00272435 1 0 LHGDN
Infection 0.00272435 1 0 LHGDN
Helicobacter pylori infection 0.002714419 10 0 BeFree
Pharyngitis 0.002171535 8 0 BeFree
Malignant neoplasm of gastrointestinal tract 0.002171535 8 0 BeFree
Duodenal Ulcer 0.001628651 6 0 BeFree
Gastric Adenocarcinoma 0.001628651 6 0 BeFree
Multiple Endocrine Neoplasia Type 1 0.001357209 5 0 BeFree
Pituitary Diseases 0.001357209 5 0 BeFree
Neuroendocrine Tumors 0.001357209 5 0 BeFree
Carcinoid tumor no ICD-O subtype 0.001357209 5 0 BeFree
Malignant neoplasm of breast 0.001085767 4 0 BeFree
Gastritis, Atrophic 0.001085767 4 0 BeFree
Hypercalcemia 0.001085767 4 0 BeFree
Neoplasm Metastasis 0.001085767 4 0 BeFree
Pancreatic Neoplasm 0.001085767 4 0 BeFree
Scarlet Fever 0.001085767 4 0 BeFree
Malignant neoplasm of lung 0.001085767 4 0 BeFree
Breast Carcinoma 0.001085767 4 0 BeFree
Adenoma 0.000814326 3 0 BeFree
Astrocytoma 0.000814326 3 0 BeFree
Dyspepsia 0.000814326 3 0 BeFree
Gastritis 0.000814326 3 0 BeFree
Rheumatic Fever 0.000814326 3 0 BeFree
Rheumatic Heart Disease 0.000814326 3 0 BeFree
Streptococcal Infections 0.000814326 3 0 BeFree
Atrophic condition of skin 0.000814326 3 0 BeFree
Tumor Progression 0.000814326 3 0 BeFree
Secondary malignant neoplasm of liver 0.000814326 3 0 BeFree
Carcinoma of lung 0.000814326 3 0 BeFree
Anemia, Pernicious 0.000542884 2 0 BeFree
Endocrine Gland Neoplasms 0.000542884 2 0 BeFree
Glioma 0.000542884 2 0 BeFree
Hyperparathyroidism 0.000542884 2 0 BeFree
Impetigo 0.000542884 2 0 BeFree
insulinoma 0.000542884 2 0 BeFree
Jervell-Lange Nielsen Syndrome 0.000542884 2 0 BeFree
Meningitis 0.000542884 2 0 BeFree
Adenomatous Polyposis Coli 0.000542884 2 0 BeFree
Precancerous Conditions 0.000542884 2 0 BeFree
Tonsillitis 0.000542884 2 0 BeFree
Small cell carcinoma of lung 0.000542884 2 0 BeFree
Medullary carcinoma of thyroid 0.000542884 2 0 BeFree
Islet Cell Tumor 0.000542884 2 0 BeFree
Adenocarcinoma of pancreas 0.000542884 2 0 BeFree
Malignant Glioma 0.000542884 2 0 BeFree
Enterochromaffin-like cell carcinoid 0.000542884 2 0 BeFree
pancreatic gastrinoma 0.000542884 2 0 BeFree
Acute tonsillitis 0.000271442 1 0 BeFree
Bacteremia 0.000271442 1 0 BeFree
Bronchioloalveolar Adenocarcinoma 0.000271442 1 0 BeFree
Mental Depression 0.000271442 1 0 BeFree
Depressive disorder 0.000271442 1 0 BeFree
Diabetes Mellitus, Insulin-Dependent 0.000271442 1 0 BeFree
Peptic Esophagitis 0.000271442 1 0 BeFree
Gastrointestinal Neoplasms 0.000271442 1 0 BeFree
Glioblastoma 0.000271442 1 0 BeFree
Graves Disease 0.000271442 1 0 BeFree
Heart Diseases 0.000271442 1 0 BeFree
Hernia 0.000271442 1 0 BeFree
HIV Infections 0.000271442 1 0 BeFree
leukemia 0.000271442 1 0 BeFree
Chronic Lymphocytic Leukemia 0.000271442 1 0 BeFree
Long QT Syndrome 0.000271442 1 0 BeFree
Medulloblastoma 0.000271442 1 0 BeFree
Nodule 0.000271442 1 0 BeFree
Osteoporosis 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
Parathyroid Diseases 0.000271442 1 0 BeFree
polyps 0.000271442 1 0 BeFree
Septicemia 0.000271442 1 0 BeFree
Skin Ulcer 0.000271442 1 0 BeFree
Gastric ulcer 0.000271442 1 0 BeFree
Thyroiditis 0.000271442 1 0 BeFree
Severe Combined Immunodeficiency 0.000271442 1 0 BeFree
Hypogammaglobulinemia 0.000271442 1 0 BeFree
Soft Tissue Infections 0.000271442 1 0 BeFree
Acute glomerulonephritis 0.000271442 1 0 BeFree
Neuroectodermal Tumor, Primitive 0.000271442 1 0 BeFree
Adenomatous Polyps 0.000271442 1 0 BeFree
gliosarcoma 0.000271442 1 0 BeFree
Hyperparathyroidism, Primary 0.000271442 1 0 BeFree
X-linked agammaglobulinemia 0.000271442 1 0 BeFree
Necrotizing fasciitis 0.000271442 1 0 BeFree
Gastrointestinal Stromal Tumors 0.000271442 1 0 BeFree
Hereditary pancreatitis 0.000271442 1 0 BeFree
Age related macular degeneration 0.000271442 1 0 BeFree
Sepsis 0.000271442 1 0 BeFree
Familial hyperparathyroidism 0.000271442 1 0 BeFree
Healing ulcer 0.000271442 1 0 BeFree
Streptococcal toxic shock syndrome 0.000271442 1 0 BeFree
Gastric Carcinoid Tumor 0.000271442 1 1 BeFree
Gastro-esophageal reflux disease with esophagitis 0.000271442 1 0 BeFree
AICARDI-GOUTIERES SYNDROME 1 0.000271442 1 0 BeFree
Adenomatous polyp of colon 0.000271442 1 0 BeFree
Infectious disease of lung 0.000271442 1 0 BeFree
ovarian neoplasm 0.000271442 1 0 BeFree
Malignant neoplasm of ovary 0.000271442 1 0 BeFree
Intestinal Polyposis 0.000271442 1 0 BeFree
Adenocarcinoma of large intestine 0.000271442 1 0 BeFree
Xenograft Model 0.000271442 1 0 BeFree
Multiple endocrine neoplasia (MEN) Syndrome 0.000271442 1 0 BeFree
GASTRIC CANCER, INTESTINAL 0.000271442 1 0 BeFree
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