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Gastrin is a hormone whose main function is to stimulate secretion of hydrochloric acid by the gastric mucosa, which results in gastrin formation inhibition. This hormone also acts as a mitogenic factor for gastrointestinal epithelial cells. Gastrin has two biologically active peptide forms, G34 and G17. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  胃泌素是一种激素,其主要功能是由胃粘膜,这导致胃泌素形成的抑制,刺激盐酸分泌。这种激素也充当胃肠上皮细胞促有丝分裂因子。胃泌素具有两个生物活性肽的形式,G34和G17。 [由RefSeq的,2008年7月提供]
GAST基因(以及对应的蛋白质)的细胞分布位置:
GAST基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Stomach Neoplasms | 0.126263026 | 5 | 0 | BeFree_CTD_human_LHGDN |
| Adenocarcinoma | 0.124895885 | 10 | 0 | BeFree_CTD_human_LHGDN |
| Colonic Neoplasms | 0.123267234 | 4 | 0 | BeFree_CTD_human_LHGDN |
| Lung Neoplasms | 0.12272435 | 2 | 0 | CTD_human_LHGDN |
| Peptic Ulcer | 0.120542884 | 3 | 0 | BeFree_CTD_human |
| Barrett Esophagus | 0.12 | 1 | 0 | CTD_human |
| Gastrointestinal Diseases | 0.12 | 1 | 0 | CTD_human |
| Reperfusion Injury | 0.12 | 1 | 0 | CTD_human |
| Stomach Carcinoma | 0.009500466 | 35 | 0 | BeFree |
| Colorectal Neoplasms | 0.008715934 | 5 | 0 | BeFree_LHGDN |
| Malignant neoplasm of stomach | 0.00868614 | 32 | 0 | BeFree |
| Malignant tumor of colon | 0.005700279 | 21 | 0 | BeFree |
| Colon Carcinoma | 0.005700279 | 21 | 0 | BeFree |
| Metaplasia | 0.0054487 | 2 | 0 | LHGDN |
| Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | 0.005157396 | 19 | 0 | BeFree |
| Carcinogenesis | 0.005157396 | 19 | 0 | BeFree |
| Gastrinoma | 0.004614512 | 17 | 0 | BeFree |
| Zollinger-Ellison syndrome | 0.004353001 | 6 | 0 | BeFree_LHGDN |
| Colorectal Carcinoma | 0.004071628 | 15 | 0 | BeFree |
| Colorectal Cancer | 0.004071628 | 15 | 0 | BeFree |
| Pancreatic carcinoma | 0.003257302 | 12 | 0 | BeFree |
| Malignant neoplasm of pancreas | 0.003257302 | 12 | 0 | BeFree |
| Hemochromatosis | 0.002995792 | 1 | 0 | BeFree_LHGDN |
| Carcinoid Tumor | 0.002985861 | 11 | 0 | BeFree |
| Biliary Tract Neoplasm | 0.00272435 | 1 | 0 | LHGDN |
| Inflammation | 0.00272435 | 1 | 0 | LHGDN |
| Infection | 0.00272435 | 1 | 0 | LHGDN |
| Helicobacter pylori infection | 0.002714419 | 10 | 0 | BeFree |
| Pharyngitis | 0.002171535 | 8 | 0 | BeFree |
| Malignant neoplasm of gastrointestinal tract | 0.002171535 | 8 | 0 | BeFree |
| Duodenal Ulcer | 0.001628651 | 6 | 0 | BeFree |
| Gastric Adenocarcinoma | 0.001628651 | 6 | 0 | BeFree |
| Multiple Endocrine Neoplasia Type 1 | 0.001357209 | 5 | 0 | BeFree |
| Pituitary Diseases | 0.001357209 | 5 | 0 | BeFree |
| Neuroendocrine Tumors | 0.001357209 | 5 | 0 | BeFree |
| Carcinoid tumor no ICD-O subtype | 0.001357209 | 5 | 0 | BeFree |
| Malignant neoplasm of breast | 0.001085767 | 4 | 0 | BeFree |
| Gastritis, Atrophic | 0.001085767 | 4 | 0 | BeFree |
| Hypercalcemia | 0.001085767 | 4 | 0 | BeFree |
| Neoplasm Metastasis | 0.001085767 | 4 | 0 | BeFree |
| Pancreatic Neoplasm | 0.001085767 | 4 | 0 | BeFree |
| Scarlet Fever | 0.001085767 | 4 | 0 | BeFree |
| Malignant neoplasm of lung | 0.001085767 | 4 | 0 | BeFree |
| Breast Carcinoma | 0.001085767 | 4 | 0 | BeFree |
| Adenoma | 0.000814326 | 3 | 0 | BeFree |
| Astrocytoma | 0.000814326 | 3 | 0 | BeFree |
| Dyspepsia | 0.000814326 | 3 | 0 | BeFree |
| Gastritis | 0.000814326 | 3 | 0 | BeFree |
| Rheumatic Fever | 0.000814326 | 3 | 0 | BeFree |
| Rheumatic Heart Disease | 0.000814326 | 3 | 0 | BeFree |
| Streptococcal Infections | 0.000814326 | 3 | 0 | BeFree |
| Atrophic condition of skin | 0.000814326 | 3 | 0 | BeFree |
| Tumor Progression | 0.000814326 | 3 | 0 | BeFree |
| Secondary malignant neoplasm of liver | 0.000814326 | 3 | 0 | BeFree |
| Carcinoma of lung | 0.000814326 | 3 | 0 | BeFree |
| Anemia, Pernicious | 0.000542884 | 2 | 0 | BeFree |
| Endocrine Gland Neoplasms | 0.000542884 | 2 | 0 | BeFree |
| Glioma | 0.000542884 | 2 | 0 | BeFree |
| Hyperparathyroidism | 0.000542884 | 2 | 0 | BeFree |
| Impetigo | 0.000542884 | 2 | 0 | BeFree |
| insulinoma | 0.000542884 | 2 | 0 | BeFree |
| Jervell-Lange Nielsen Syndrome | 0.000542884 | 2 | 0 | BeFree |
| Meningitis | 0.000542884 | 2 | 0 | BeFree |
| Adenomatous Polyposis Coli | 0.000542884 | 2 | 0 | BeFree |
| Precancerous Conditions | 0.000542884 | 2 | 0 | BeFree |
| Tonsillitis | 0.000542884 | 2 | 0 | BeFree |
| Small cell carcinoma of lung | 0.000542884 | 2 | 0 | BeFree |
| Medullary carcinoma of thyroid | 0.000542884 | 2 | 0 | BeFree |
| Islet Cell Tumor | 0.000542884 | 2 | 0 | BeFree |
| Adenocarcinoma of pancreas | 0.000542884 | 2 | 0 | BeFree |
| Malignant Glioma | 0.000542884 | 2 | 0 | BeFree |
| Enterochromaffin-like cell carcinoid | 0.000542884 | 2 | 0 | BeFree |
| pancreatic gastrinoma | 0.000542884 | 2 | 0 | BeFree |
| Acute tonsillitis | 0.000271442 | 1 | 0 | BeFree |
| Bacteremia | 0.000271442 | 1 | 0 | BeFree |
| Bronchioloalveolar Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
| Mental Depression | 0.000271442 | 1 | 0 | BeFree |
| Depressive disorder | 0.000271442 | 1 | 0 | BeFree |
| Diabetes Mellitus, Insulin-Dependent | 0.000271442 | 1 | 0 | BeFree |
| Peptic Esophagitis | 0.000271442 | 1 | 0 | BeFree |
| Gastrointestinal Neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Glioblastoma | 0.000271442 | 1 | 0 | BeFree |
| Graves Disease | 0.000271442 | 1 | 0 | BeFree |
| Heart Diseases | 0.000271442 | 1 | 0 | BeFree |
| Hernia | 0.000271442 | 1 | 0 | BeFree |
| HIV Infections | 0.000271442 | 1 | 0 | BeFree |
| leukemia | 0.000271442 | 1 | 0 | BeFree |
| Chronic Lymphocytic Leukemia | 0.000271442 | 1 | 0 | BeFree |
| Long QT Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Medulloblastoma | 0.000271442 | 1 | 0 | BeFree |
| Nodule | 0.000271442 | 1 | 0 | BeFree |
| Osteoporosis | 0.000271442 | 1 | 0 | BeFree |
| Ovarian Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Parathyroid Diseases | 0.000271442 | 1 | 0 | BeFree |
| polyps | 0.000271442 | 1 | 0 | BeFree |
| Septicemia | 0.000271442 | 1 | 0 | BeFree |
| Skin Ulcer | 0.000271442 | 1 | 0 | BeFree |
| Gastric ulcer | 0.000271442 | 1 | 0 | BeFree |
| Thyroiditis | 0.000271442 | 1 | 0 | BeFree |
| Severe Combined Immunodeficiency | 0.000271442 | 1 | 0 | BeFree |
| Hypogammaglobulinemia | 0.000271442 | 1 | 0 | BeFree |
| Soft Tissue Infections | 0.000271442 | 1 | 0 | BeFree |
| Acute glomerulonephritis | 0.000271442 | 1 | 0 | BeFree |
| Neuroectodermal Tumor, Primitive | 0.000271442 | 1 | 0 | BeFree |
| Adenomatous Polyps | 0.000271442 | 1 | 0 | BeFree |
| gliosarcoma | 0.000271442 | 1 | 0 | BeFree |
| Hyperparathyroidism, Primary | 0.000271442 | 1 | 0 | BeFree |
| X-linked agammaglobulinemia | 0.000271442 | 1 | 0 | BeFree |
| Necrotizing fasciitis | 0.000271442 | 1 | 0 | BeFree |
| Gastrointestinal Stromal Tumors | 0.000271442 | 1 | 0 | BeFree |
| Hereditary pancreatitis | 0.000271442 | 1 | 0 | BeFree |
| Age related macular degeneration | 0.000271442 | 1 | 0 | BeFree |
| Sepsis | 0.000271442 | 1 | 0 | BeFree |
| Familial hyperparathyroidism | 0.000271442 | 1 | 0 | BeFree |
| Healing ulcer | 0.000271442 | 1 | 0 | BeFree |
| Streptococcal toxic shock syndrome | 0.000271442 | 1 | 0 | BeFree |
| Gastric Carcinoid Tumor | 0.000271442 | 1 | 1 | BeFree |
| Gastro-esophageal reflux disease with esophagitis | 0.000271442 | 1 | 0 | BeFree |
| AICARDI-GOUTIERES SYNDROME 1 | 0.000271442 | 1 | 0 | BeFree |
| Adenomatous polyp of colon | 0.000271442 | 1 | 0 | BeFree |
| Infectious disease of lung | 0.000271442 | 1 | 0 | BeFree |
| ovarian neoplasm | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of ovary | 0.000271442 | 1 | 0 | BeFree |
| Intestinal Polyposis | 0.000271442 | 1 | 0 | BeFree |
| Adenocarcinoma of large intestine | 0.000271442 | 1 | 0 | BeFree |
| Xenograft Model | 0.000271442 | 1 | 0 | BeFree |
| Multiple endocrine neoplasia (MEN) Syndrome | 0.000271442 | 1 | 0 | BeFree |
| GASTRIC CANCER, INTESTINAL | 0.000271442 | 1 | 0 | BeFree |
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