ERBB3(erb-b2 receptor tyrosine kinase 3) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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12q13
基因染色体位置图

This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  该基因编码的表皮生长因子受体(EGFR)家族的受体酪氨酸激酶的成员。这种膜结合蛋白具有神经调节蛋白结合结构域,但不活性激酶结构域。因此,它可以结合这种配位体,但通过蛋白磷酸化不是信号传送到细胞中。但是,它确实形式的异源二聚体与其它EGF受体家族成员确实具有激酶活性。异二聚导致通路从而导致细胞增殖或分化的激活。此基因和/或它的蛋白质的过表达的扩增已经报道在许多癌症,包括前列腺癌,膀胱癌,和乳房肿瘤。替代转录剪接变异体编码不同亚型进行了表征。一种同种型缺乏膜间区域和被分泌到细胞外。这种形式的作用以调节膜结合形式的活性。附加剪接变体也有报道,但还没有被充分表征。 [由RefSeq的,2008年7月提供]

ERBB3基因的碱基序列:[NCBI]
ERBB3基因的碱基突变:           显示全部snp
rs705696       rs705708       rs773116       rs773122       rs773123       rs798829       rs812826       rs877636       rs984896       rs1088696       rs1088697       rs1508211       rs2229045       rs2229046       rs2271188       rs2271189       rs2271194       rs2271195       rs2292238       rs2292239       rs3202538       rs3741499       rs3759093       rs3891921       rs4016497       rs4759229       rs7297175       rs7301038       rs7488167       rs7971751       rs10719449       rs10783779       rs10876870       rs10876871       rs11171740       rs11171743       rs11317236      
rs11835018       rs12227040       rs12320176       rs12322914       rs12817471       rs12826115       rs17118292       rs33927060       rs34379766       rs34576601       rs34986935       rs35961836       rs36035578       rs55699040       rs55702663       rs55787439       rs55880327       rs56017157       rs56073151       rs56107455       rs56112932       rs56259600       rs56387488       rs56926853       rs57237559       rs58034809       rs59334125       rs59398518       rs61938985       rs67592614       rs71074898       rs71074900       rs71446532       rs71446533       rs73338396       rs73338402       rs73340305       rs74094518       rs74094520       rs74094521       rs74094522       rs74094535       rs74443892       rs74647738       rs74928813       rs75064496       rs75101116       rs75144518       rs75375961       rs75518415       rs75526830       rs75611093       rs75668652       rs75770904       rs76079275       rs76091173       rs76219216       rs76307931       rs76373339       rs76460727       rs76678968       rs77193972       rs77228285       rs77313500       rs77322483       rs77351535       rs77365107       rs77822103       rs77830169       rs78232207       rs78467114       rs78663322       rs78667723       rs78856154       rs79020757       rs79222157       rs79335261       rs79573246       rs79581177       rs79638498       rs79663475       rs79759315       rs79768661       rs80010141       rs80185484       rs80193421       rs111240448       rs111349488       rs111656432       rs111753949       rs112003232       rs112340323       rs112478453       rs112552087       rs112578440       rs112650407       rs112651994       rs112675254       rs112882897       rs113226419       rs113267229       rs113375878       rs113453807       rs113467802       rs113780367       rs113949839       rs113975857       rs114032300       rs114402294       rs115053296       rs115311663       rs115699610       rs116905410       rs116960611       rs116991809       rs117570794       rs117846238       rs117859597       rs118067691       rs137866164       rs137870123       rs137983681       rs138072655       rs138158047       rs138338331       rs138339733       rs138429725       rs138517750       rs138548737       rs138861245       rs138906959       rs139022684       rs139140702       rs139267530       rs139301776       rs139749751       rs139774513       rs139868331       rs139969906       rs140116753       rs140454718       rs140606920       rs140648008       rs140656187       rs140670767       rs140679673       rs141054346       rs141230043       rs141292133       rs141355769       rs141435873       rs141636701       rs141700623       rs141739894       rs141742993       rs142303928       rs142358877       rs142393525       rs142406728       rs142735651       rs142809206       rs142849499       rs142878944       rs143021252       rs143122001       rs143292757       rs143406438       rs143417561       rs143473013       rs143726790       rs143742672       rs143770796       rs144377156       rs144436014       rs144510847       rs144549266       rs144558290       rs144777490       rs144785344       rs144911105       rs144969061       rs145007073       rs145070592       rs145108143       rs145174737       rs145259354       rs145359354       rs145774133       rs145873700       rs145948980       rs146486757       rs146593760       rs146615875       rs146842909       rs147010683       rs147189912       rs147206496       rs147412657       rs147436223       rs147491626       rs147802594       rs147888915       rs147905731       rs148289233       rs148448153       rs148498435       rs148560992       rs148602695       rs148655905       rs148962556       rs149181380       rs149216050       rs149279640       rs149441887       rs149495975       rs149635848       rs149790108       rs149951770       rs150001629       rs150022316       rs150160186       rs150262923       rs150312718       rs150454821       rs150528532       rs150930307       rs151083303       rs151309290       rs151311358       rs180921882       rs180986542       rs181276733       rs181291405       rs181442133       rs181620928       rs181659329       rs181858183       rs181895949       rs182154425       rs182284622       rs182361805       rs182379829       rs182563545       rs182687492       rs182692782       rs182896439       rs183131399       rs183290419       rs183499024       rs183578416       rs183933151       rs184082141       rs184179645       rs184485935       rs184532952       rs184780602       rs185231101       rs185233102       rs185362695       rs185457835       rs185534054       rs185577186       rs186080571       rs186103138       rs186183394       rs186460991       rs186476586       rs186627711       rs186628922       rs186645808       rs186838784       rs186875079       rs187008330       rs187218416       rs187277789       rs187302474       rs187482632       rs187874555       rs188032649       rs188312953       rs188400828       rs188543816       rs188555938       rs188795493       rs188923723       rs188955993       rs189193848       rs189413187       rs189424197       rs189445979       rs189451890       rs189789018       rs189800795       rs190031571       rs190034531       rs190036848       rs190272819       rs190516343       rs191131399       rs191209918       rs191590515       rs192146102       rs192151273       rs192237788       rs192488000       rs192491617       rs192748125       rs192782355       rs192934821       rs199524175       rs199526131       rs199586304       rs199590684       rs199613777       rs199616683       rs199663404       rs199797901       rs199806001       rs199876654       rs199957175       rs200007116       rs200017094       rs200173838       rs200184071       rs200211366       rs200256095       rs200343222       rs200350558       rs200457259       rs200574817       rs200670489       rs200724560       rs200737450       rs200767056       rs200811061       rs200855296       rs200856864       rs200978269       rs201079200       rs201081850       rs201112536       rs201146123       rs201149603       rs201199014       rs201244150       rs201250912       rs201309981       rs201378576       rs201479792       rs201486425       rs201663351       rs201842812       rs201880960       rs201892971       rs201942735       rs201958747       rs202048840       rs202162033       rs202205409       rs202221237       rs202222293       rs267603577       rs367629214       rs367645135       rs367759159       rs368166407       rs368190353       rs368234642       rs368317187       rs368321597       rs368322587       rs368322892       rs368508813       rs368652265       rs368698085       rs368700608       rs368720651       rs368728752       rs368891812       rs368965033       rs368991808       rs369186738       rs369300309       rs369605715       rs369698449       rs369758674       rs369782777       rs369874280       rs369877866       rs369939866       rs369994613       rs370025321       rs370066418       rs370099171       rs370221639       rs370272057       rs370552281       rs370581727       rs370634710       rs370847503       rs370849499       rs370856466       rs370880989       rs371000187       rs371005132       rs371016430       rs371094129       rs371109792       rs371111282       rs371164238       rs371250480       rs371346857       rs371429378       rs371519679       rs371577741       rs371658091       rs371693596       rs371866354       rs371965660       rs372066092       rs372171124       rs372688193       rs372697579       rs372703573       rs372736362       rs372743283       rs372787253       rs372816263       rs373016496       rs373276051       rs373276728       rs373278933       rs373295408       rs373454755       rs373473538       rs373474079       rs373476674       rs373527304       rs373595919       rs373609369       rs373727653       rs373814789       rs373831196       rs373838865       rs373840207       rs373842106       rs373877469       rs373960466       rs374000753       rs374124592       rs374485725       rs374610753       rs374619740       rs374643843       rs374738957       rs374782318       rs374869935       rs374926284       rs374953448       rs375138004       rs375142740       rs375145270       rs375153329       rs375212605       rs375320188       rs375335792       rs375546286       rs375640443       rs375740977       rs375932235       rs376130778       rs376206732       rs376234145       rs376243222       rs376339937       rs376362887       rs376471167       rs376536781       rs376595441       rs376652138       rs376656358       rs376662224       rs376698708       rs376804415       rs376902345       rs376939275       rs377036506       rs377075104       rs377181290       rs377315464       rs377380727       rs377384549       rs377479010       rs377479457       rs377498727       rs397770929       rs398019696       rs398019697       rs527249652       rs527525537       rs527600141       rs527728968       rs527746499       rs527861386       rs527931493       rs527996959       rs528182386       rs528261428       rs528386835       rs528498655       rs528518765       rs528721550       rs528997090       rs529078898       rs529287124       rs529349327       rs529391068       rs529431800       rs529498703       rs529588820       rs529665455       rs529681686       rs529743964       rs529864676       rs530461427       rs530514718       rs530593671       rs530695217       rs530901322       rs530971245       rs531243579       rs531304096       rs531574760       rs531851249       rs531870282       rs531979247       rs532044461       rs532129585       rs532503081       rs532645445       rs532910077       rs533024092       rs533137623       rs533262937       rs533396528       rs533478554       rs533648867       rs534155843       rs534229354       rs534446191       rs534803783       rs534911035       rs534913814       rs534918586       rs535186970       rs535457958       rs535618129       rs535762069       rs535831126       rs536028186       rs536345070       rs536672285       rs536697358       rs536734825       rs536805768       rs536823810       rs536881047       rs537147697       rs537427649       rs537539761       rs537612088       rs537805661       rs537867649       rs537875605       rs537939229       rs537940264       rs538200506       rs538256730       rs538319940       rs538374419       rs538404507       rs538526313       rs538659927       rs538722977       rs538859685       rs539054062       rs539116990       rs539455222       rs539519025       rs539681351       rs540060042       rs540193561       rs540234156       rs540419748       rs540442776       rs540444132       rs540581426       rs541376085       rs541437383       rs541536069       rs541704461       rs541947408       rs542106370       rs542493721       rs542546359       rs542865599       rs543070149       rs543080916       rs543082548       rs543309579       rs543742419       rs543912694       rs543942622       rs544162273       rs544165333       rs544239965       rs544290150       rs544323123       rs544426955       rs544630584       rs544678821       rs544947004       rs545092829       rs545244900       rs545415217       rs545477540       rs545574670       rs545742674       rs545799132       rs546727763       rs546895088       rs546924189       rs546953300       rs546956237       rs547182987       rs547261509       rs547284508       rs547590580       rs547752484       rs547823901       rs547869059       rs548094452       rs548302761       rs548359026       rs548496368       rs548514069       rs548565641       rs548907427       rs549011194       rs549520423       rs549551729       rs549568636       rs549674430       rs549747369       rs549756783       rs550253578       rs550478087       rs550541706       rs550646668       rs550756030       rs550901146       rs550941832       rs550963195       rs551020295       rs551223118       rs551404301       rs551575420       rs551639580       rs551838098       rs551967367       rs552030360       rs552144290       rs552306307       rs552361637       rs552539100       rs552548827       rs553090262       rs553151640       rs553368460       rs553653837       rs553870326       rs554139459       rs554271166       rs554294309       rs554332418       rs554353576       rs554417031       rs554602534       rs555018899       rs555070992       rs555074566       rs555359169       rs555414441       rs555468041       rs555475940       rs555476092       rs555527897       rs555770357       rs556017020       rs556070672       rs556265371       rs556288815       rs556527342       rs556677810       rs556909555       rs557077076       rs557470204       rs557728984       rs557851175       rs557858969       rs557922321       rs558338532       rs558409679       rs558410431       rs558470428       rs558621582       rs558825504       rs558851810       rs558888955       rs558922236       rs558975107       rs558990919       rs559078261       rs559656662       rs559937373       rs559956465       rs560166892       rs560238325       rs560348338       rs560360962       rs560422339       rs560594495       rs560635272       rs560666292       rs560668114       rs560729505       rs560822924       rs560882038       rs560884226       rs561191209       rs561399419       rs561443686       rs561463201       rs561522113       rs561538895       rs561743080       rs561787077       rs561797765       rs561801044       rs561863195       rs561924561       rs561999778       rs562548767       rs562675506       rs562794068       rs562808125       rs563087947       rs563270024       rs563414938       rs563581883       rs564128963       rs564204026       rs564234252       rs564272028       rs564333686       rs564591346       rs564662072       rs565402748       rs565461245       rs565480296       rs565601090       rs565840792       rs565907678       rs566062709       rs566107230       rs566185593       rs566285257       rs566462059       rs566679785       rs566949466       rs567016549       rs567115144       rs567194321       rs567205523       rs567373027       rs567979739       rs568175210       rs568319076       rs568356771       rs568360568       rs568383978       rs568500721       rs568603419       rs568855787       rs568978172       rs569027720       rs569039515       rs569056556       rs569206705       rs569343770       rs569378810       rs569386846       rs569403749       rs569440687       rs569487317       rs569549786       rs569569840       rs569826765       rs569887971       rs570057511       rs570086942       rs570154608       rs570606716       rs570614098       rs570637025       rs570687337       rs570697638       rs570745693       rs570748881       rs571095209       rs571250102       rs571269605       rs571397011       rs571429414       rs571791159       rs571955559       rs572129384       rs572129872       rs572394708       rs572578210       rs572735121       rs572748001       rs572809661       rs572843373       rs572923795       rs573158454       rs573483361       rs573731884       rs573798308       rs573799234       rs573887175       rs574059831       rs574075766       rs574149579       rs574417750       rs574735703       rs574799217       rs574810605       rs574868480       rs575823381       rs575949471       rs576402458       rs576559805       rs576617052       rs576623741       rs577122289       rs577236188       rs577296673       rs577477447       rs577827061       rs577881575       rs577996168       rs578231398       rs745349643       rs745388282       rs745431908       rs745464238       rs745487835       rs745490480       rs745555924       rs745658752       rs745696175       rs745708003       rs745744610       rs745764657       rs745801537       rs745833715       rs745926358       rs745930963       rs745974664       rs746010261       rs746015375       rs746048147       rs746054406       rs746101600       rs746211618       rs746234503       rs746262131       rs746277687       rs746289457       rs746329416       rs746395481       rs746569100       rs746612908       rs746628854       rs746673930       rs746806935       rs746842107       rs746888057       rs746899911       rs746900380       rs746909010       rs746955432       rs747026534       rs747131244       rs747136840       rs747154798       rs747256428       rs747344439       rs747360963       rs747423003       rs747424637       rs747453114       rs747462791       rs747554823       rs747687493       rs747724574       rs747748100       rs747758405       rs747781332       rs747848453       rs747884274       rs747927084       rs747963339       rs747978213       rs747986362       rs748051476       rs748071169       rs748150381       rs748210428       rs748286265       rs748287828       rs748319015       rs748329753       rs748439445       rs748544096       rs748548967       rs748562918       rs748595358       rs748627495       rs748811895       rs748817889       rs748825294       rs748832619       rs748856478       rs748901952       rs748965595       rs749096091       rs749101304       rs749128162       rs749208755       rs749255674       rs749372152       rs749408634       rs749453307       rs749460480       rs749647572       rs749690850       rs749691155       rs749701200       rs749784326       rs749837397       rs749968833       rs749981785       rs750011302       rs750047837       rs750109086       rs750173361       rs750199027       rs750240460       rs750252178       rs750272011       rs750286654       rs750291956       rs750292694       rs750302728       rs750476308       rs750513378       rs750514165       rs750531252       rs750546129       rs750564739       rs750714635       rs750783773       rs750813770       rs750839021       rs750884386       rs750884540       rs750936517       rs750947241       rs751025983       rs751083456       rs751110954       rs751111371       rs751174259       rs751333751       rs751355083       rs751374743       rs751413071       rs751422999       rs751428454       rs751430378       rs751610199       rs751623771       rs751658102       rs751682177       rs751682254       rs751707747       rs751735085       rs751770045       rs751837696       rs751842876       rs751866833       rs751870363       rs751896559       rs752065363       rs752120492       rs752180033       rs752186697       rs752248295       rs752253764       rs752273376       rs752289630       rs752412861       rs752507110       rs752509988       rs752570404       rs752572904       rs752581968       rs752745097       rs752771982       rs752803014       rs753010641       rs753025352       rs753041411       rs753193028       rs753282289       rs753381982       rs753446923       rs753461903       rs753503203       rs753556193       rs753623628       rs753637842       rs753656627       rs753670569       rs753681468       rs753709849       rs753723245       rs753778551       rs753940174       rs753971721       rs753989381       rs754056576       rs754106965       rs754129713       rs754133603       rs754198128       rs754234296       rs754255751       rs754275955       rs754286267       rs754287711       rs754444047       rs754469778       rs754497375       rs754594339       rs754618467       rs754698641       rs754708975       rs754711278       rs754936669       rs754937875       rs754961576       rs755162824       rs755187499       rs755195879       rs755202592       rs755257778       rs755294151       rs755304842       rs755384403       rs755433568       rs755437657       rs755456606       rs755509709       rs755540867       rs755595923       rs755643469       rs755689533       rs755700670       rs755757062       rs755759349       rs755808253       rs755855285       rs755864862       rs755919824       rs755981274       rs755994398       rs756031721       rs756039555       rs756049409       rs756068516       rs756082396       rs756121964       rs756201607       rs756327666       rs756341535       rs756381479       rs756432396       rs756434433       rs756498804       rs756535556       rs756565541       rs756590738       rs756648267       rs756656037       rs756767445       rs756770310       rs756926213       rs756961453       rs757012593       rs757097775       rs757100419       rs757187439       rs757229785       rs757257914       rs757334966       rs757391301       rs757425458       rs757433330       rs757518347       rs757559484       rs757577500       rs757581362       rs757588627       rs757588784       rs757654877       rs757680970       rs757695889       rs757712749       rs757732235       rs757785908       rs757941835       rs758078343       rs758119433       rs758130617       rs758159081       rs758297377       rs758336051       rs758350871       rs758402895       rs758421385       rs758455948       rs758492908       rs758519672       rs758521616       rs758564931       rs758573987       rs758578409       rs758623034       rs758724788       rs758743468       rs758858051       rs758858885       rs758866721       rs758891575       rs759029932       rs759044259       rs759090081       rs759192377       rs759229675       rs759266496       rs759321206       rs759355041       rs759445625       rs759458720       rs759472988       rs759562930       rs759585997       rs759635172       rs759646874       rs759649945       rs759676510       rs759678672       rs759686993       rs759714291       rs759751183       rs759756702       rs759764423       rs759781351       rs759860285       rs759969948       rs759982748       rs759985332       rs760053751       rs760055268       rs760209480       rs760246763       rs760283890       rs760284985       rs760334728       rs760336631       rs760382937       rs760414488       rs760481338       rs760515344       rs760520385       rs760612025       rs760684405       rs760709621       rs760733324       rs760776632       rs760796344       rs760891277       rs760949072       rs761002408       rs761041279       rs761188556       rs761205665       rs761229179       rs761253211       rs761278557       rs761279693       rs761321127       rs761374421       rs761437304       rs761478277       rs761544555       rs761627530       rs761638351       rs761652415       rs761685287       rs761706940       rs761919744       rs761947335       rs761982226       rs762010415       rs762035321       rs762035500       rs762050460       rs762123925       rs762129530       rs762130727       rs762283307       rs762295587       rs762323088       rs762337678       rs762354688       rs762425528       rs762488062       rs762522193       rs762638258       rs762674444       rs762765641       rs762869866       rs762898008       rs762900471       rs762905722       rs762942580       rs762991374       rs762993161       rs763091526       rs763108970       rs763162378       rs763184020       rs763214247       rs763264762       rs763298736       rs763378170       rs763449522       rs763471956       rs763475378       rs763500317       rs763529509       rs763532328       rs763600586       rs763623076       rs763638733       rs763753546       rs763808045       rs763820950       rs763910919       rs763914719       rs764048066       rs764063127       rs764134881       rs764145735       rs764152740       rs764216267       rs764233895       rs764254944       rs764464919       rs764501445       rs764505233       rs764545275       rs764554418       rs764648141       rs764658539       rs764666189       rs764713576       rs764788295       rs764836319       rs764889168       rs764891356       rs764925612       rs764967058       rs764972594       rs764987438       rs765061604       rs765171065       rs765174667       rs765179217       rs765201265       rs765217252       rs765277521       rs765290695       rs765301443       rs765388650       rs765496438       rs765582426       rs765619131       rs765639633       rs765693205       rs765774011       rs765810588       rs765878149       rs766025310       rs766049369       rs766082508       rs766147426       rs766158165       rs766176702       rs766190994       rs766225730       rs766278040       rs766315268       rs766331240       rs766389874       rs766445884       rs766463645       rs766558873       rs766618651       rs766619595       rs766735121       rs766782872       rs766784893       rs766792372       rs766897145       rs766932138       rs767016749       rs767074695       rs767179070       rs767246337       rs767247925       rs767345764       rs767359947       rs767380736       rs767437646       rs767467479       rs767474997       rs767516997       rs767540617       rs767597316       rs767661045       rs767692749       rs767745935       rs767747698       rs767905298       rs767929395       rs767946969       rs767977511       rs768003972       rs768004540       rs768015586       rs768059072       rs768081452       rs768081701       rs768118549       rs768169383       rs768175062       rs768226214       rs768244757       rs768296093       rs768334019       rs768347264       rs768349544       rs768352400       rs768429976       rs768445052       rs768499912       rs768676897       rs768735795       rs768736698       rs768860685       rs768913280       rs768950621       rs769041526       rs769144559       rs769204920       rs769228905       rs769235392       rs769251414       rs769258043       rs769285620       rs769377225       rs769400680       rs769417912       rs769586905       rs769634421       rs769661725       rs769723853       rs769768196       rs769811937       rs769847060       rs769847079       rs769880860       rs769897949       rs769932894       rs770040279       rs770120793       rs770217913       rs770291856       rs770301264       rs770327755       rs770352348       rs770391904       rs770418548       rs770446901       rs770517547       rs770543666       rs770651825       rs770712528       rs770750571       rs770761268       rs770800582       rs770810033       rs770822086       rs770870486       rs770884727       rs770956274       rs770976516       rs771054853       rs771107986       rs771120188       rs771187693       rs771231548       rs771269574       rs771433216       rs771442726       rs771484411       rs771497238       rs771520731       rs771529756       rs771534313       rs771536549       rs771613701       rs771629308       rs771708814       rs771709447       rs771842590       rs771886822       rs771899301       rs771935902       rs771978779       rs771983298       rs772010472       rs772081729       rs772186703       rs772277526       rs772330811       rs772361694       rs772365638       rs772400489       rs772436902       rs772484121       rs772486476       rs772576333       rs772678619       rs772693789       rs772747085       rs772755519       rs772810438       rs772863490       rs772887693       rs772908961       rs773134874       rs773145082       rs773184763       rs773187406       rs773189933       rs773250703       rs773255987       rs773372734       rs773429549       rs773491347       rs773530299       rs773545951       rs773658634       rs773682670       rs773690291       rs773743395       rs773745272       rs773773362       rs773838967       rs773839032       rs773864864       rs773866522       rs773923119       rs773926940       rs773994974       rs774002664       rs774015628       rs774044496       rs774095251       rs774273587       rs774283255       rs774290699       rs774326613       rs774338322       rs774380215       rs774390282       rs774415293       rs774493771       rs774523341       rs774536437       rs774581725       rs774589520       rs774669307       rs774723821       rs774819745       rs774847268       rs774951032       rs774955844       rs775019515       rs775042280       rs775048781       rs775138327       rs775164134       rs775183935       rs775223707       rs775279860       rs775382907       rs775439390       rs775537159       rs775613666       rs775624359       rs775624369       rs775627128       rs775643757       rs775674615       rs775764667       rs775791630       rs775802394       rs775899344       rs775916001       rs775924433       rs776033298       rs776039068       rs776088161       rs776099242       rs776195897       rs776203562       rs776289675       rs776293588       rs776317437       rs776335440       rs776358318       rs776526512       rs776597149       rs776675136       rs776679159       rs776728303       rs776766992       rs776770257       rs776780937       rs776852010       rs776943898       rs777034879       rs777051335       rs777073878       rs777074650       rs777106152       rs777336821       rs777353067       rs777359364       rs777373519       rs777380336       rs777381368       rs777498890       rs777500852       rs777501187       rs777547093       rs777551696       rs777560897       rs777632845       rs777650340       rs777676889       rs777718028       rs777784585       rs777804420       rs777968329       rs778104039       rs778244400       rs778249980       rs778250041       rs778472746       rs778519373       rs778529173       rs778578418       rs778618876       rs778646490       rs778689388       rs778703567       rs778747536       rs778752060       rs778783934       rs779013163       rs779029750       rs779069907       rs779099720       rs779170330       rs779200761       rs779277467       rs779330902       rs779368926       rs779380573       rs779413213       rs779437595       rs779497191       rs779598315       rs779625413       rs779637486       rs779665393       rs779681658       rs779725686       rs779802097       rs779857851       rs779859165       rs779896968       rs779910792       rs779911233       rs779924065       rs779965253       rs779979084       rs780001504       rs780012513       rs780132789       rs780170030       rs780212356       rs780257144       rs780308521       rs780394534       rs780407772       rs780421722       rs780527140       rs780549253       rs780636036       rs780639000       rs780753707       rs780804718       rs780825658       rs780883720       rs780914174       rs780965539       rs780969100       rs780976894       rs781015952       rs781056272       rs781057007       rs781058680       rs781094247       rs781143393       rs781263660       rs781370237       rs781370860       rs781376470       rs781394944       rs781395095       rs781502670       rs781540863       rs781557723       rs781661153       rs781739506       rs781747216      

ERBB3基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GGGAGATCACAGGTTACCTG
60
CTCCAATGGTTGTCAAATTGGA
60
CTTCCTGCAGTGGATTCGA
60
AGGTTGGGCAATGGTAGAG
59
TGTTTAGGACAAACACTGGT
57
TCACTGTCAAAGCCATTGTC
59
CTACGAGAGGTGTGAGGTG
59
TTCTCGAATCCACTGCAGG
60
TCAGCTCACCGAGATTCTG
59
TCCCTCCAGTCAATTGTGTC
60
AAGGACAATGGCAGAAGCT
60
TCTTGGTCAATGTCTGGCA
59
AATTGACTGGAGGGACATCG
60
GACAGCTTCTGCCATTGTC
59
GACTATGTCCCAAAGCCTG
58
CAAATCCATCAATGTTGCTCG
59
TAAGTGGATGGCCCTTGAG
59
CAAACTGTCACACCATAGCTC
59
CTGCTGACTCCTGTTACCC
60
GAGGGAGTACCTTTGAGGTG
60
      尚未收录相关数据

ERBB3基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

ERBB3基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0004672
B3KWG5(UniProtKB)
IEA
GO:0006468
B3KWG5(UniProtKB)
IEA
GO:0004714
B4DGQ7(UniProtKB)
IEA
GO:0005524
B4DGQ7(UniProtKB)
IEA
GO:0007169
B4DGQ7(UniProtKB)
IEA
GO:0016021
B4DGQ7(UniProtKB)
IEA
GO:0018108
B4DGQ7(UniProtKB)
IEA
GO:0004672
F8VW56(UniProtKB)
IEA
GO:0005524
F8VW56(UniProtKB)
IEA
GO:0006468
F8VW56(UniProtKB)
IEA
GO:0004713
F8VYK4(UniProtKB)
IEA
GO:0016021
F8VYK4(UniProtKB)
IEA
GO:0018108
F8VYK4(UniProtKB)
IEA
GO:0000165
P21860(UniProtKB)
TAS
GO:0003197
P21860(UniProtKB)
IEA
GO:0004713
P21860(UniProtKB)
TAS
GO:0004713
P21860(UniProtKB)
TAS
GO:0004888
P21860(UniProtKB)
ISS
GO:0005088
P21860(UniProtKB)
TAS
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005515
P21860(UniProtKB)
IPI
GO:0005524
P21860(UniProtKB)
IEA
GO:0005615
P21860(UniProtKB)
IDA
GO:0005622
P21860(UniProtKB)
IEA
GO:0005622
P21860(UniProtKB)
IEA
GO:0005622
P21860(UniProtKB)
IEA
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005886
P21860(UniProtKB)
TAS
GO:0005887
P21860(UniProtKB)
TAS
GO:0007162
P21860(UniProtKB)
IDA
GO:0007165
P21860(UniProtKB)
IDA
GO:0007169
P21860(UniProtKB)
ISS
GO:0007422
P21860(UniProtKB)
ISS
GO:0007507
P21860(UniProtKB)
ISS
GO:0009968
P21860(UniProtKB)
IDA
GO:0014037
P21860(UniProtKB)
ISS
GO:0014065
P21860(UniProtKB)
IDA
GO:0014066
P21860(UniProtKB)
TAS
GO:0014068
P21860(UniProtKB)
TAS
GO:0016323
P21860(UniProtKB)
IDA
GO:0016324
P21860(UniProtKB)
IEA
GO:0016328
P21860(UniProtKB)
IEA
GO:0018108
P21860(UniProtKB)
IEA
GO:0019838
P21860(UniProtKB)
IPI
GO:0019838
P21860(UniProtKB)
ISS
GO:0021545
P21860(UniProtKB)
ISS
GO:0030296
P21860(UniProtKB)
IDA
GO:0038128
P21860(UniProtKB)
TAS
GO:0038132
P21860(UniProtKB)
IDA
GO:0042060
P21860(UniProtKB)
NAS
GO:0042127
P21860(UniProtKB)
IDA
GO:0042802
P21860(UniProtKB)
IPI
GO:0042802
P21860(UniProtKB)
IPI
GO:0042803
P21860(UniProtKB)
NAS
GO:0043235
P21860(UniProtKB)
IDA
GO:0043235
P21860(UniProtKB)
ISS
GO:0043524
P21860(UniProtKB)
ISS
GO:0043547
P21860(UniProtKB)
IEA
GO:0046854
P21860(UniProtKB)
IEA
GO:0046934
P21860(UniProtKB)
TAS
GO:0046982
P21860(UniProtKB)
IDA
GO:0046982
P21860(UniProtKB)
IPI
GO:0048015
P21860(UniProtKB)
TAS
GO:0051048
P21860(UniProtKB)
IDA
GO:0051402
P21860(UniProtKB)
IMP
GO:0061098
P21860(UniProtKB)
IMP
GO:0070886
P21860(UniProtKB)
IEA
GO:0097192
P21860(UniProtKB)
IMP
GO:2000145
P21860(UniProtKB)
TAS
GO:0004713
P21860(UniProtKB)
IDA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控ERBB3基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Lethal Congenital Contracture Syndrome 2 0.36 0 0 CLINVAR_CTD_human_ORPHANET
Diabetes Mellitus, Insulin-Dependent 0.160315489 20 3 BeFree_GAD_GWASCAT
Mammary Neoplasms 0.137964821 21 0 BeFree_CTD_human_LHGDN
Prostatic Neoplasms 0.133621751 5 0 CTD_human_LHGDN
Lung Neoplasms 0.128715934 5 1 BeFree_CTD_human_LHGDN
Disease Progression 0.125091382 3 0 CTD_human_GAD_LHGDN
gallbladder neoplasm 0.12 1 0 CTD_human
Obesity 0.12 1 1 GWASCAT
Nasopharyngeal carcinoma 0.12 1 0 CTD_human
Chronic Obstructive Airway Disease 0.08 1 0 RGD
Mouth Neoplasms 0.08 1 0 RGD
Wallerian Degeneration 0.08 1 0 RGD
Median Neuropathy 0.08 1 0 RGD
Malignant neoplasm of breast 0.018458047 68 1 BeFree
Breast Carcinoma 0.018186605 67 1 BeFree
Neoplasm Metastasis 0.012244679 18 0 BeFree_LHGDN
Schizophrenia 0.012082858 9 0 BeFree_GAD_LHGDN
melanoma 0.007891677 11 0 BeFree_LHGDN
Non-Small Cell Lung Carcinoma 0.005981653 12 0 BeFree_LHGDN
Stomach Neoplasms 0.0054487 2 0 LHGDN
Carcinogenesis 0.004885954 18 0 BeFree
Malignant neoplasm of lung 0.004810009 10 0 BeFree_GAD
Malignant neoplasm of ovary 0.004810009 10 0 BeFree_GAD
Autoimmune Diseases 0.004734064 2 0 GAD
Diabetes Mellitus, Non-Insulin-Dependent 0.004734064 2 1 GAD
Adenocarcinoma 0.00408156 5 0 BeFree_LHGDN
Sarcoma, Clear Cell 0.003267234 3 0 BeFree_LHGDN
Ductal Carcinoma 0.003267234 3 0 BeFree_LHGDN
Glioma 0.002909916 3 0 BeFree_GAD
Astrocytoma 0.00272435 1 0 LHGDN
Bladder Neoplasm 0.00272435 1 0 LHGDN
Carcinoma, Transitional Cell 0.00272435 1 0 LHGDN
Charcot-Marie-Tooth Disease 0.00272435 1 0 LHGDN
Fibroid Tumor 0.00272435 1 0 LHGDN
Pulmonary Fibrosis 0.00272435 1 0 LHGDN
Thyroid Neoplasm 0.00272435 1 0 LHGDN
Ovarian Carcinoma 0.002714419 10 0 BeFree
Brain Neoplasms 0.002638474 2 0 BeFree_GAD
Carcinoma of lung 0.002442977 9 0 BeFree
Colorectal Cancer 0.002442977 9 0 BeFree
Addison Disease 0.002367032 1 0 GAD
Rheumatoid Arthritis 0.002367032 1 0 GAD
Celiac Disease 0.002367032 1 0 GAD
Crohn Disease 0.002367032 1 0 GAD
Hypertensive disease 0.002367032 1 0 GAD
Lupus Erythematosus, Systemic 0.002367032 1 0 GAD
Multiple Sclerosis 0.002367032 1 0 GAD
Coronary Artery Disease 0.002367032 1 0 GAD
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 0.002367032 1 0 GAD
Juvenile arthritis 0.002367032 1 0 GAD
Malignant tumor of colon 0.002171535 8 0 BeFree
Malignant neoplasm of stomach 0.002171535 8 0 BeFree
Tumor Progression 0.002171535 8 0 BeFree
Pancreatic carcinoma 0.002171535 8 0 BeFree
Malignant neoplasm of pancreas 0.002171535 8 0 BeFree
Colon Carcinoma 0.002171535 8 0 BeFree
Colorectal Carcinoma 0.001900093 7 0 BeFree
Squamous cell carcinoma 0.001628651 6 0 BeFree
Malignant neoplasm of prostate 0.001628651 6 0 BeFree
Prostate carcinoma 0.001628651 6 0 BeFree
Stomach Carcinoma 0.001628651 6 0 BeFree
Adenocarcinoma of lung (disorder) 0.001357209 5 0 BeFree
Glioblastoma 0.001085767 4 0 BeFree
Secondary malignant neoplasm of lymph node 0.001085767 4 0 BeFree
Rhabdoid Tumor of the Kidney 0.001085767 4 0 BeFree
Squamous cell carcinoma of the head and neck 0.001085767 4 0 BeFree
Acute Erythroblastic Leukemia 0.000814326 3 0 BeFree
Metastatic malignant neoplasm to brain 0.000814326 3 0 BeFree
Carcinoma breast stage IV 0.000814326 3 0 BeFree
Adenoma 0.000542884 2 0 BeFree
Malignant neoplasm of urinary bladder 0.000542884 2 0 BeFree
Renal Cell Carcinoma 0.000542884 2 0 BeFree
Diabetes Mellitus 0.000542884 2 6 BeFree
Immunologic Deficiency Syndromes 0.000542884 2 0 BeFree
Multiple Myeloma 0.000542884 2 0 BeFree
Osteosarcoma 0.000542884 2 0 BeFree
Esophageal carcinoma 0.000542884 2 0 BeFree
Cancer of Head and Neck 0.000542884 2 0 BeFree
Pilocytic Astrocytoma 0.000542884 2 0 BeFree
Osteosarcoma of bone 0.000542884 2 0 BeFree
Epithelial ovarian cancer 0.000542884 2 0 BeFree
Carcinoma of bladder 0.000542884 2 0 BeFree
Adenocarcinoma of large intestine 0.000542884 2 0 BeFree
Hormone refractory prostate cancer 0.000542884 2 0 BeFree
Mammary Tumorigenesis 0.000542884 2 0 BeFree
Arthrogryposis 0.000271442 1 0 BeFree
Neurogenic Urinary Bladder 0.000271442 1 0 BeFree
Carcinoid Tumor 0.000271442 1 0 BeFree
Rectal Carcinoma 0.000271442 1 0 BeFree
Noninfiltrating Intraductal Carcinoma 0.000271442 1 0 BeFree
Choriocarcinoma 0.000271442 1 0 BeFree
Colonic Neoplasms 0.000271442 1 0 BeFree
Colorectal Neoplasms 0.000271442 1 0 BeFree
Patent ductus arteriosus 0.000271442 1 0 BeFree
Ganglioneuroma 0.000271442 1 0 BeFree
Intestinal Neoplasms 0.000271442 1 0 BeFree
Meningioma 0.000271442 1 0 BeFree
Neuroblastoma 0.000271442 1 0 BeFree
Acoustic Neuroma 0.000271442 1 0 BeFree
Prolactinoma 0.000271442 1 0 BeFree
Rhabdomyosarcoma 0.000271442 1 0 BeFree
Palindromic rheumatism 0.000271442 1 0 BeFree
Polymyositis 0.000271442 1 6 BeFree
Pancreatitis, Chronic 0.000271442 1 0 BeFree
Squamous cell carcinoma of lung 0.000271442 1 0 BeFree
Cutaneous Melanoma 0.000271442 1 0 BeFree
Secondary malignant neoplasm of lung 0.000271442 1 0 BeFree
Secondary malignant neoplasm of bone 0.000271442 1 0 BeFree
Autoimmune thyroid disease 0.000271442 1 4 BeFree
Diabetes, Autoimmune 0.000271442 1 0 BeFree
Choroid Plexus Papilloma 0.000271442 1 0 BeFree
Alveolar rhabdomyosarcoma 0.000271442 1 0 BeFree
Carcinoma, Lobular 0.000271442 1 0 BeFree
Ganglioneuroblastoma 0.000271442 1 0 BeFree
childhood rhabdomyosarcoma 0.000271442 1 0 BeFree
Comedone 0.000271442 1 0 BeFree
Carcinoma, Small Cell 0.000271442 1 0 BeFree
Erythroblastosis 0.000271442 1 0 BeFree
Stage II Colon Cancer 0.000271442 1 0 BeFree
Prostate cancer recurrent 0.000271442 1 0 BeFree
alveolar childhood rhabdomyosarcoma 0.000271442 1 0 BeFree
Adenocarcinoma Of Esophagus 0.000271442 1 0 BeFree
Squamous cell carcinoma of oropharynx 0.000271442 1 0 BeFree
Adenocarcinoma of pancreas 0.000271442 1 0 BeFree
Cervix carcinoma 0.000271442 1 0 BeFree
Carcinoid tumor no ICD-O subtype 0.000271442 1 0 BeFree
Hydatidiform Mole, Partial 0.000271442 1 0 BeFree
Multiple malignancy 0.000271442 1 0 BeFree
Secondary malignant neoplasm of omentum 0.000271442 1 0 BeFree
Endometrial Carcinoma 0.000271442 1 0 BeFree
Secondary malignant neoplasm of liver 0.000271442 1 0 BeFree
Tumor Initiation 0.000271442 1 0 BeFree
Progressive Neoplastic Disease 0.000271442 1 0 BeFree
Complete hydatidiform mole 0.000271442 1 0 BeFree
Central neuroblastoma 0.000271442 1 0 BeFree
Idiopathic Inflammatory Myopathies 0.000271442 1 0 BeFree
Breast adenocarcinoma 0.000271442 1 0 BeFree
ovarian neoplasm 0.000271442 1 0 BeFree
Metastatic Prostate Carcinoma 0.000271442 1 0 BeFree
Gestational Trophoblastic Neoplasms 0.000271442 1 0 BeFree
Mesenchymal Cell Neoplasm 0.000271442 1 0 BeFree
Pancreatic Ductal Adenocarcinoma 0.000271442 1 0 BeFree
Epithelioma 0.000271442 1 0 BeFree
Benign Prostatic Hyperplasia 0.000271442 1 0 BeFree
Non-Neoplastic Disorder 0.000271442 1 0 BeFree
LETHAL CONGENITAL CONTRACTURE SYNDROME 1 0.000271442 1 0 BeFree
Gestational trophoblastic disease 0.000271442 1 0 BeFree
Clear-cell metastatic renal cell carcinoma 0.000271442 1 0 BeFree
HYDATIDIFORM MOLE, RECURRENT, 1 0.000271442 1 0 BeFree
Progressive cGVHD 0.000271442 1 0 BeFree
ESTROGEN RESISTANCE 0.000271442 1 0 BeFree
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