CCL4L1(chemokine (C-C motif) ligand 4-like 1) 转至新版数据库
基因简称(symbol)
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
omim代码
entrez码
vega基因码
ensembl基因码
基因家族(gene family)
refseq数据库代号
更多...
基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库
收起
This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this family member is similar to the chemokine (C-C motif) ligand 4 product, which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals, where most individuals have one to five copies. This gene copy contains a non-consensus splice acceptor site at the 3' terminal exon found in other highly similar gene copies, and it thus uses other alternative splice sites for the 3' terminal exon, resulting in multiple transcript variants. [provided by RefSeq, Apr 2014]
[中文简述(自动翻译):] 这个基因是那些对染色体的q臂17细胞因子是炎性和免疫调节过程起作用分泌蛋白的一个家族聚集几个细胞因子基因之一。通过这个家族成员编码的蛋白质是相似的趋化因子（C-C基序）配体4的产品，其通过结合至细胞受体的CCR5抑制HIV条目。该基因的拷贝数的个体，其中，大多数人有一至五个拷贝的不同而不同。这个基因拷贝包含在3非一致剪接受体位点‘末端外显子在其他高度相似基因拷贝发现，因此它使用其它替代的剪接位点的3‘末端外显子，从而产生多个转录变体。 [由RefSeq的，2014年4月提供]
CCL4L1基因的碱基突变：
显示全部snp
rs74162059
rs139880913
rs140287155
rs142940468
rs147970464
rs148287175
rs151202755
rs184899362
rs199602306
rs199695019
rs200548593
rs201331353
rs369863268
rs370895301
rs374269885
rs376364944
rs529646096
rs532193042
rs532228961
rs536625637
rs536659845
rs537512655
rs538042687
rs538426981
rs539296580
rs539810579
rs543866215
rs545601365
rs546126568
rs546396363
rs546521000
rs546987092
rs551081508
rs551926903
rs551963791
rs553313080
rs553699223
rs557276658
rs557866064
rs558975503
rs560002136
rs560039959
rs560801483
rs560898016
rs562619710
rs562743559
rs564986297
rs566379892
rs567173443
rs567638176
rs567698597
rs571681400
rs573504925
rs573542172
rs574168317
rs574260404
rs575251900
rs575269067
rs575839113
rs745316213
rs745996851
rs747143736
rs748414284
rs748693445
rs748934057
rs749465931
rs749982568
rs750364464
rs751241763
rs752281032
rs753229540
rs753421950
rs754521977
rs755652166
rs755742165
rs757229584
rs757780195
rs758429847
rs758670544
rs758832266
rs759805762
rs760702459
rs761472245
rs762718541
rs763941168
rs765314165
rs765992731
rs766370764
rs766631638
rs767511078
rs767601242
rs768942230
rs769041475
rs769590820
rs770082833
rs770989233
rs772403535
rs772667666
rs773303236
rs773349081
rs774215735
rs774787661
rs776816094
rs776908706
rs778315216
rs779349546
rs779812604
rs780114777
rs780380521
rs780756347
rs781258391
rs781509134
基因本体信息
CCL4L1基因（以及对应的蛋白质）的细胞分布位置：
- 溶酶体
- 内涵体
- 细胞核
- 细胞质
- 液泡
- 细胞膜
- 细胞外基质
- 内质网
- 线粒体
- 高尔基体
- 细胞骨架
CCL4L1基因的本体（GO）信息：
GO库代码
对应的蛋白质
来源代码
GO:0002548
Q8NHW4(UniProtKB)
IBA
GO:0005515
Q8NHW4(UniProtKB)
IPI
GO:0005615
Q8NHW4(UniProtKB)
IBA
GO:0006954
Q8NHW4(UniProtKB)
IBA
GO:0007186
Q8NHW4(UniProtKB)
IBA
GO:0008009
Q8NHW4(UniProtKB)
IBA
GO:0030593
Q8NHW4(UniProtKB)
IBA
GO:0043547
Q8NHW4(UniProtKB)
IBA
GO:0048020
Q8NHW4(UniProtKB)
IBA
GO:0048247
Q8NHW4(UniProtKB)
IBA
GO:0050729
Q8NHW4(UniProtKB)
IBA
GO:0070098
Q8NHW4(UniProtKB)
IBA
GO:0070374
Q8NHW4(UniProtKB)
IBA
GO:0071346
Q8NHW4(UniProtKB)
IBA
GO:0071347
Q8NHW4(UniProtKB)
IBA
GO:0071356
Q8NHW4(UniProtKB)
IBA
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Fibrosis, Liver | 0.011672 | 43 | 0 | BeFree |
| HIV Infections | 0.008143256 | 30 | 0 | BeFree |
| Liver Cirrhosis | 0.003528744 | 13 | 0 | BeFree |
| Cirrhosis | 0.002442977 | 9 | 0 | BeFree |
| Down Syndrome | 0.001628651 | 6 | 0 | BeFree |
| Liver Failure | 0.001085767 | 4 | 0 | BeFree |
| Liver regeneration disorder | 0.001085767 | 4 | 0 | BeFree |
| Rheumatoid Arthritis | 0.000814326 | 3 | 0 | BeFree |
| Hepatitis | 0.000814326 | 3 | 0 | BeFree |
| Hepatitis A | 0.000814326 | 3 | 0 | BeFree |
| Chronic Lymphocytic Leukemia | 0.000814326 | 3 | 0 | BeFree |
| Liver neoplasms | 0.000814326 | 3 | 0 | BeFree |
| Tuberculosis | 0.000814326 | 3 | 0 | BeFree |
| Liver Failure, Acute | 0.000814326 | 3 | 0 | BeFree |
| Liver carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Arteriosclerosis | 0.000542884 | 2 | 0 | BeFree |
| Atherosclerosis | 0.000542884 | 2 | 0 | BeFree |
| Hepatitis C | 0.000542884 | 2 | 0 | BeFree |
| Liver diseases | 0.000542884 | 2 | 0 | BeFree |
| Lymphoma | 0.000542884 | 2 | 0 | BeFree |
| Malaria | 0.000542884 | 2 | 0 | BeFree |
| Psoriasis | 0.000542884 | 2 | 0 | BeFree |
| Carcinogenesis | 0.000542884 | 2 | 0 | BeFree |
| Abscess | 0.000271442 | 1 | 0 | BeFree |
| Adenoma | 0.000271442 | 1 | 0 | BeFree |
| AIDS Dementia Complex | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of breast | 0.000271442 | 1 | 0 | BeFree |
| Ulcerative Colitis | 0.000271442 | 1 | 0 | BeFree |
| Crohn Disease | 0.000271442 | 1 | 0 | BeFree |
| Delirium | 0.000271442 | 1 | 0 | BeFree |
| Presenile dementia | 0.000271442 | 1 | 0 | BeFree |
| Diabetes Mellitus, Non-Insulin-Dependent | 0.000271442 | 1 | 0 | BeFree |
| Experimental Autoimmune Encephalomyelitis | 0.000271442 | 1 | 0 | BeFree |
| Glioblastoma | 0.000271442 | 1 | 0 | BeFree |
| Gonorrhea | 0.000271442 | 1 | 0 | BeFree |
| Hay fever | 0.000271442 | 1 | 0 | BeFree |
| Hepatitis B | 0.000271442 | 1 | 0 | BeFree |
| Hepatitis, Alcoholic | 0.000271442 | 1 | 0 | BeFree |
| Influenza | 0.000271442 | 1 | 0 | BeFree |
| leukemia | 0.000271442 | 1 | 0 | BeFree |
| Hairy Cell Leukemia | 0.000271442 | 1 | 0 | BeFree |
| Leukemia, Myelocytic, Acute | 0.000271442 | 1 | 0 | BeFree |
| Leukemia, T-Cell | 0.000271442 | 1 | 0 | BeFree |
| Adult T-Cell Lymphoma/Leukemia | 0.000271442 | 1 | 0 | BeFree |
| Liver Cirrhosis, Alcoholic | 0.000271442 | 1 | 0 | BeFree |
| Lung Neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Mucocutaneous Lymph Node Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Mycoses | 0.000271442 | 1 | 0 | BeFree |
| Peripheral Neuropathy | 0.000271442 | 1 | 0 | BeFree |
| Septicemia | 0.000271442 | 1 | 0 | BeFree |
| Cerebrovascular accident | 0.000271442 | 1 | 0 | BeFree |
| Thyroiditis | 0.000271442 | 1 | 0 | BeFree |
| Ureteral obstruction | 0.000271442 | 1 | 0 | BeFree |
| Active tuberculosis | 0.000271442 | 1 | 0 | BeFree |
| Primary Sj�gren's syndrome | 0.000271442 | 1 | 0 | BeFree |
| Hepatic necrosis | 0.000271442 | 1 | 0 | BeFree |
| Systemic candidiasis | 0.000271442 | 1 | 0 | BeFree |
| Aortic Aneurysm, Thoracic | 0.000271442 | 1 | 0 | BeFree |
| Autoimmune thyroid disease | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of lung | 0.000271442 | 1 | 0 | BeFree |
| Sepsis | 0.000271442 | 1 | 0 | BeFree |
| Iron Overload | 0.000271442 | 1 | 0 | BeFree |
| Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse | 0.000271442 | 1 | 0 | BeFree |
| Multinodular goiter | 0.000271442 | 1 | 0 | BeFree |
| hiv-infection/aids | 0.000271442 | 1 | 0 | BeFree |
| Dementia | 0.000271442 | 1 | 0 | BeFree |
| Metabolic Syndrome X | 0.000271442 | 1 | 0 | BeFree |
| Hepatitis C, Chronic | 0.000271442 | 1 | 0 | BeFree |
| Breast Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
| Aortic valve disorder | 0.000271442 | 1 | 0 | BeFree |
| Chronic Kidney Diseases | 0.000271442 | 1 | 0 | BeFree |
| Alcoholic Steatohepatitis | 0.000271442 | 1 | 0 | BeFree |
| AIDS (Disease) | 0.000271442 | 1 | 0 | BeFree |
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