HIST1H4C基因详情-基因数据库-基因云馆

HIST1H4C(histone cluster 1, H4c)

基因简称(symbol)

HIST1H4C [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

H4/g|dJ221C16.1

基因家族代码(gene_family_id)

864 [HGNC] [GenScript]

omim代码

602827

entrez码

8364 [Vega]

vega基因码

OTTHUMG00000014429

ensembl基因码

ENSG00000197061 [Ensembl]

基因家族(gene family)

Histones

refseq数据库代号

NM_003542

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

06p22.1

同源基因名称(alias name)

基因名称批准使用时间(date_approved_reserved)

1998-09-07T00:00:00Z

基因简称更名时间(date_symbol_changed)

2003-02-21T00:00:00Z

基因名称更名时间(date_name_changed)

2006-10-11T00:00:00Z

更新时间(date_modified)

2014-11-19T00:00:00Z

ucsc码

uc003ngi.3

ena

X60486

ccds数据码

CCDS4583

uniprot数据码

P62805

pubmed代码

9119399|12408966

mgd码

MGI:2140113

rgd码

生命科学数据库(lsdb)

更新时间(date modified)

2014-11-19T00:00:00Z

cosmic

HIST1H4C

mirbase

基因曾用简称(prev symbol)

H4FG

基因曾用名称(prev name)

H4 histone family, member G|histone 1, H4c

homeodb

cosmic

HIST1H4C

snornabase

bioparadigms slc

orphanet

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

6p22.1

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):] 组蛋白是负责在真核生物染色体纤维的核小体结构基本核蛋白质。每四个核心组蛋白中的两个分子（H2A，H2B，H3和H4）形成八聚体，其周围约146的DNA的碱基被包裹在重复单元，称为核小体。接头组蛋白，H1与染色质成高阶结构的压实核小体和功能之间的接头DNA相互作用。这种基因是无内含子并且编码所述组蛋白H4家族的一个成员。从这个基因转录缺乏聚腺苷酸尾，而是包含回文终端元件。该基因大组蛋白基因簇中发现[由RefSeq的，2008年7月提供] 6号染色体

OMIM数据库中对HIST1H4C基因的介绍 Wikipedia数据库中对HIST1H4C基因的介绍

HIST1H4C基因的碱基序列：[NCBI]

HIST1H4C基因的碱基突变：显示全部snp

rs198850 rs198851 rs198852 rs198853 rs198854 rs198855 rs198856 rs198857 rs1543680 rs2229767 rs2229768 rs2237227 rs2237228 rs7743957 rs10636318 rs13191939 rs13194932 rs57358798 rs61735681 rs73389440 rs74293937 rs77229316 rs77248387 rs112290793 rs112633510 rs113071031 rs113641425 rs116169498 rs137946858 rs138617314 rs139153107 rs139800869 rs139978722 rs141696499 rs141888021 rs142325880 rs142328147

rs144035835 rs144469714 rs145591548 rs145952724 rs147057053 rs147927897 rs148953304 rs149192513 rs149299525 rs149616889 rs150070448 rs150173561 rs150455092 rs151064538 rs180926252 rs183187281 rs183837379 rs184771900 rs185062320 rs187711162 rs188071783 rs190167982 rs191297356 rs192517421 rs192954403 rs199622849 rs199850152 rs200049708 rs200327357 rs200804123 rs201173942 rs201314432 rs201486698 rs201557297 rs201728993 rs202081290 rs368379063 rs368885785 rs369373723 rs372349838 rs373426362 rs374054604 rs374090002 rs374272109 rs374531800 rs374983731 rs376246574 rs377271397 rs528599238 rs529239071 rs529782443 rs530842613 rs531320362 rs531742943 rs532253812 rs533320117 rs533685388 rs533900494 rs533946409 rs534295522 rs535197319 rs538001977 rs539816007 rs540552983 rs541270496 rs541582625 rs543694435 rs543778249 rs544164160 rs545191057 rs547424745 rs547548487 rs547851567 rs548111237 rs548516283 rs550210245 rs550568315 rs552328900 rs554151928 rs554860213 rs556133648 rs559489588 rs560544580 rs560897393 rs562599530 rs563704898 rs565099303 rs567054193 rs568125259 rs568284928 rs568625359 rs568738780 rs569177700 rs570168191 rs570384478 rs570860486 rs572057045 rs572999891 rs574688374 rs575552966 rs577239168 rs577276722 rs578245436 rs745478604 rs745995878 rs746227657 rs746933560 rs747221249 rs747230614 rs747462828 rs747607271 rs747837605 rs747940169 rs748976885 rs749224080 rs749731572 rs749828287 rs750016056 rs750302109 rs750973238 rs751464949 rs752054338 rs752528297 rs752710671 rs752840232 rs754919310 rs755011404 rs755066393 rs755585231 rs756027136 rs756093749 rs756104062 rs756402378 rs756565143 rs757537589 rs757621417 rs758409836 rs758943077 rs759750063 rs760135344 rs760318601 rs760373858 rs760454062 rs760528290 rs760797342 rs761231459 rs762429421 rs762464717 rs762794238 rs762951326 rs763103771 rs763181691 rs763485719 rs763949586 rs764182762 rs764260360 rs764631185 rs765500082 rs766080912 rs766120783 rs766567490 rs767392986 rs767447937 rs768229225 rs768282563 rs768378084 rs768755096 rs768884406 rs769941868 rs770738668 rs771076651 rs771210683 rs771490255 rs771922227 rs772431822 rs772729140 rs773040347 rs773163391 rs773228610 rs774330776 rs774741400 rs774848596 rs775647676 rs775700808 rs775824271 rs775903667 rs776151975 rs776865242 rs776896605 rs777818031 rs777994526 rs778249149 rs778556234 rs778987751 rs779327642 rs779549794 rs779688394 rs780951094 rs781503661 rs869291342

HIST1H4C基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

CTTATCTATGAGGAGACTCGAGG

59

GCGTCTCGAATAACGTTCTC

59

TTATCTATGAGGAGACTCGAGG

58

GCGTCTCGAATAACGTTCTC

59

TTATCTATGAGGAGACTCGAGGT

60

GCGTCTCGAATAACGTTCTC

59

尚未收录相关数据

HIST1H4C基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

HIST1H4C基因的本体（GO）信息：

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控HIST1H4C基因的相关microRNA：

hsa-miR-34a hsa-miR-125b hsa-miR-100 hsa-miR-1226 hsa-miR-1229 hsa-miR-17 hsa-miR-425* hsa-miR-874 hsa-miR-92a

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Spontaneous abortion	0.002367032	1	0	GAD
Carcinogenesis	0.001085767	4	0	BeFree
Myeloid Leukemia, Chronic	0.000814326	3	0	BeFree
Liver carcinoma	0.000814326	3	0	BeFree
Lupus Erythematosus, Systemic	0.000542884	2	0	BeFree
Mammary Neoplasms	0.000542884	2	0	BeFree
Non-Small Cell Lung Carcinoma	0.000271442	1	0	BeFree
Squamous cell carcinoma	0.000271442	1	0	BeFree
Congenital chromosomal disease	0.000271442	1	0	BeFree
Glioma	0.000271442	1	0	BeFree
Leukemia, Myelocytic, Acute	0.000271442	1	0	BeFree
melanoma	0.000271442	1	0	BeFree
Neoplasm Metastasis	0.000271442	1	0	BeFree
Rett Syndrome	0.000271442	1	0	BeFree
Systemic Scleroderma	0.000271442	1	0	BeFree
Small cell carcinoma of lung	0.000271442	1	0	BeFree
Embryonal Carcinoma	0.000271442	1	0	BeFree
Muscular Dystrophy, Facioscapulohumeral	0.000271442	1	0	BeFree
Malignant neoplasm of colon stage IV	0.000271442	1	0	BeFree
Non-small cell lung cancer stage I	0.000271442	1	0	BeFree
Squamous cell carcinoma of esophagus	0.000271442	1	0	BeFree
Multiple malignancy	0.000271442	1	0	BeFree
Colorectal Cancer	0.000271442	1	0	BeFree