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The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  由该基因编码的蛋白质是参与有丝分裂的调节蛋白。用P34(CDC2)的基因产物复合物,以形成成熟促进因子(MPF)。两种备选的转录已发现,组成性表达的转录和细胞周期调节的转录,它是在G2 / M期主要表达。不同的成绩单,从使用替代转录起始位点的结果。 [由RefSeq的,2008年7月提供]
CCNB1基因(以及对应的蛋白质)的细胞分布位置:
CCNB1基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
IGA Glomerulonephritis | 0.12 | 1 | 0 | CTD_human |
Polycystic Ovary Syndrome | 0.12 | 1 | 0 | CTD_human |
Diabetes Mellitus, Experimental | 0.08 | 1 | 0 | RGD |
Hyperplasia | 0.08 | 1 | 0 | RGD |
Liver Neoplasms, Experimental | 0.08 | 1 | 0 | RGD |
Reperfusion Injury | 0.08 | 1 | 0 | RGD |
Seizures | 0.08 | 1 | 0 | RGD |
Squamous cell carcinoma | 0.006534468 | 6 | 0 | BeFree_LHGDN |
Malignant neoplasm of breast | 0.005624334 | 13 | 0 | BeFree_GAD |
Renal Cell Carcinoma | 0.003267234 | 3 | 0 | BeFree_LHGDN |
leukemia | 0.003267234 | 3 | 0 | BeFree_LHGDN |
Neoplasm Metastasis | 0.003267234 | 3 | 0 | BeFree_LHGDN |
Breast Carcinoma | 0.003257302 | 12 | 0 | BeFree |
Mammary Neoplasms | 0.002995792 | 2 | 0 | BeFree_LHGDN |
Esophageal Diseases | 0.00272435 | 1 | 0 | LHGDN |
Medulloblastoma | 0.00272435 | 1 | 0 | LHGDN |
Prostatic Neoplasms | 0.00272435 | 1 | 0 | LHGDN |
B-Cell Lymphomas | 0.00272435 | 1 | 0 | LHGDN |
Ganglioglioma | 0.00272435 | 1 | 0 | LHGDN |
Disease Progression | 0.00272435 | 1 | 0 | LHGDN |
Malformations of Cortical Development | 0.00272435 | 1 | 0 | LHGDN |
Malignant neoplasm of ovary | 0.002367032 | 1 | 0 | GAD |
Prostate carcinoma | 0.002171535 | 8 | 0 | BeFree |
Liver carcinoma | 0.002171535 | 8 | 0 | BeFree |
Malignant neoplasm of prostate | 0.001900093 | 7 | 0 | BeFree |
Colorectal Carcinoma | 0.001357209 | 5 | 0 | BeFree |
Colon Carcinoma | 0.001357209 | 5 | 0 | BeFree |
Colorectal Cancer | 0.001357209 | 5 | 0 | BeFree |
Malignant tumor of colon | 0.001085767 | 4 | 0 | BeFree |
Non-Small Cell Lung Carcinoma | 0.001085767 | 4 | 0 | BeFree |
Colorectal Neoplasms | 0.001085767 | 4 | 0 | BeFree |
Glioma | 0.001085767 | 4 | 0 | BeFree |
Malignant neoplasm of stomach | 0.001085767 | 4 | 0 | BeFree |
Stomach Carcinoma | 0.001085767 | 4 | 0 | BeFree |
Malignant neoplasm of lung | 0.000814326 | 3 | 0 | BeFree |
Cervix carcinoma | 0.000814326 | 3 | 0 | BeFree |
Carcinoma of lung | 0.000814326 | 3 | 0 | BeFree |
Malignant tumor of cervix | 0.000542884 | 2 | 0 | BeFree |
Glioblastoma | 0.000542884 | 2 | 0 | BeFree |
Leukemia, T-Cell | 0.000542884 | 2 | 0 | BeFree |
Adult T-Cell Lymphoma/Leukemia | 0.000542884 | 2 | 0 | BeFree |
Osteosarcoma | 0.000542884 | 2 | 0 | BeFree |
Retinoblastoma | 0.000542884 | 2 | 0 | BeFree |
Esophageal carcinoma | 0.000542884 | 2 | 0 | BeFree |
Cholangiocarcinoma | 0.000542884 | 2 | 0 | BeFree |
Squamous cell carcinoma of esophagus | 0.000542884 | 2 | 0 | BeFree |
Vulval intraepithelial neoplasia | 0.000542884 | 2 | 0 | BeFree |
Endometrial Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Osteosarcoma of bone | 0.000542884 | 2 | 0 | BeFree |
Carcinogenesis | 0.000542884 | 2 | 0 | BeFree |
Secondary malignant neoplasm of lymph node | 0.000542884 | 2 | 0 | BeFree |
Adenoma | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of urinary bladder | 0.000271442 | 1 | 0 | BeFree |
Brain Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of endometrium | 0.000271442 | 1 | 0 | BeFree |
Choriocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Colonic Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Shigella Infections | 0.000271442 | 1 | 0 | BeFree |
Endometriosis | 0.000271442 | 1 | 0 | BeFree |
Leukemia, Myelocytic, Acute | 0.000271442 | 1 | 0 | BeFree |
Lymphoma, Follicular | 0.000271442 | 1 | 0 | BeFree |
Multiple Myeloma | 0.000271442 | 1 | 0 | BeFree |
Ovarian Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Ovarian Diseases | 0.000271442 | 1 | 0 | BeFree |
Adenomatous Polyposis Coli | 0.000271442 | 1 | 0 | BeFree |
Tonsillitis | 0.000271442 | 1 | 0 | BeFree |
Hepatoblastoma | 0.000271442 | 1 | 0 | BeFree |
Gastrointestinal Stromal Tumors | 0.000271442 | 1 | 0 | BeFree |
Liver and Intrahepatic Biliary Tract Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Restenosis | 0.000271442 | 1 | 0 | BeFree |
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of liver | 0.000271442 | 1 | 0 | BeFree |
Epithelial ovarian cancer | 0.000271442 | 1 | 0 | BeFree |
Carcinoma of bladder | 0.000271442 | 1 | 0 | BeFree |
Invasive Ductal Breast Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Liver regeneration disorder | 0.000271442 | 1 | 0 | BeFree |
Epithelioma | 0.000271442 | 1 | 0 | BeFree |
Non-Neoplastic Disorder | 0.000271442 | 1 | 0 | BeFree |
Uterine Corpus Cancer | 0.000271442 | 1 | 0 | BeFree |
Nasopharyngeal carcinoma | 0.000271442 | 1 | 0 | BeFree |
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