AIF1(allograft inflammatory factor 1) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

基因染色体位置

基因染色体位置

6p21.3
基因染色体位置图

基因简述

基因简述

This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

[中文简述(自动翻译):]  该基因是由细胞因子和干扰素诱导。其蛋白质产物被认为是参与血管平滑肌细胞的生长负调节，这有助于抗炎响应于血管壁创伤。已发现该基因编码不同亚型三个抄本变形。 [由RefSeq的，2008年9月提供]

OMIM数据库中对AIF1基因的介绍     Wikipedia数据库中对AIF1基因的介绍

基因序列

基因序列

AIF1基因的碱基序列：[NCBI]

基因突变

基因突变

AIF1基因的碱基突变：           显示全部snp
rs2259571       rs2259571       rs2259571       rs2259571       rs2259571       rs2259571       rs2269475       rs2269475       rs2269475       rs2269475       rs2269475       rs2269475       rs2736182       rs2736182       rs2736182       rs2736182       rs2736182       rs2736182       rs2844475       rs2844475       rs2844475       rs2844475       rs2844475       rs2844475       rs2844476       rs2844476       rs2844476       rs2844476       rs2844476       rs2844476       rs2857597       rs2857597       rs2857597       rs2857597       rs2857597       rs2857597       rs2857600      
rs2857600       rs2857600       rs2857600       rs2857600       rs2857697       rs2857697       rs2857697       rs2857697       rs2857697       rs2857697       rs2857698       rs2857698       rs2857698       rs2857698       rs2857698       rs2857698       rs3132451       rs3132451       rs3132451       rs3132451       rs3132451       rs3132451       rs4711274       rs4711274       rs4711274       rs4711274       rs4711274       rs4711274       rs11299892       rs28732150       rs28732150       rs28732150       rs28732150       rs28732150       rs28732150       rs34451818       rs34451818       rs34451818       rs34451818       rs34451818       rs34451818       rs45552734       rs45552734       rs45552734       rs45552734       rs45552734       rs45552734       rs45593732       rs45593732       rs45593732       rs45593732       rs45593732       rs45593732       rs66884629       rs66884629       rs66884629       rs66884629       rs66884629       rs66884629       rs71563354       rs71563354       rs71563354       rs71563354       rs71563354       rs71563354       rs73396284       rs73396284       rs73396284       rs73396284       rs73396284       rs73396284       rs73728950       rs73728950       rs73728950       rs73728950       rs73728950       rs73728950       rs74710159       rs74710159       rs74710159       rs74710159       rs74710159       rs74710159       rs77099654       rs77099654       rs77099654       rs77099654       rs77099654       rs77099654       rs113261526       rs113261526       rs113261526       rs113261526       rs113261526       rs113261526       rs113340037       rs113340037       rs113340037       rs113340037       rs113340037       rs113340037       rs113457910       rs113457910       rs113457910       rs113457910       rs113457910       rs113457910       rs115999438       rs115999438       rs115999438       rs115999438       rs115999438       rs115999438       rs116690630       rs116690630       rs116690630       rs116690630       rs116690630       rs116690630       rs138775006       rs138775006       rs138775006       rs138775006       rs138775006       rs138775006       rs139488702       rs139488702       rs139488702       rs139488702       rs139488702       rs139488702       rs139967967       rs139967967       rs139967967       rs139967967       rs139967967       rs139967967       rs141088133       rs141088133       rs141088133       rs141088133       rs141088133       rs141088133       rs141116503       rs141116503       rs141116503       rs141116503       rs141116503       rs141116503       rs141840862       rs141840862       rs141840862       rs141840862       rs141840862       rs141840862       rs141876692       rs141876692       rs141876692       rs141876692       rs141876692       rs141876692       rs141987249       rs141987249       rs141987249       rs141987249       rs141987249       rs141987249       rs142360884       rs142360884       rs142360884       rs142360884       rs142360884       rs142360884       rs142881117       rs142881117       rs142881117       rs142881117       rs142881117       rs142881117       rs144177667       rs144177667       rs144177667       rs144177667       rs144177667       rs144177667       rs145825376       rs145825376       rs145825376       rs145825376       rs145825376       rs145825376       rs146296064       rs146296064       rs146296064       rs146296064       rs146296064       rs146296064       rs146545719       rs146545719       rs146545719       rs146545719       rs146545719       rs146545719       rs146806048       rs146806048       rs146806048       rs146806048       rs146806048       rs146806048       rs148006965       rs148006965       rs148006965       rs148006965       rs148006965       rs148006965       rs148658163       rs148658163       rs148658163       rs148658163       rs148658163       rs148658163       rs148972430       rs148972430       rs148972430       rs148972430       rs148972430       rs148972430       rs149533361       rs149533361       rs149533361       rs149533361       rs149533361       rs149533361       rs149845947       rs149845947       rs149845947       rs149845947       rs149845947       rs149845947       rs150136811       rs150136811       rs150136811       rs150136811       rs150136811       rs150136811       rs151051615       rs151051615       rs151051615       rs151051615       rs151051615       rs151051615       rs180964007       rs180964007       rs180964007       rs180964007       rs180964007       rs180964007       rs181418640       rs181418640       rs181418640       rs181418640       rs181418640       rs181418640       rs181628368       rs181628368       rs181628368       rs181628368       rs181628368       rs181628368       rs182941161       rs182941161       rs182941161       rs182941161       rs182941161       rs182941161       rs183878693       rs183878693       rs183878693       rs183878693       rs183878693       rs183878693       rs184274756       rs184274756       rs184274756       rs184274756       rs184274756       rs184274756       rs184649744       rs184649744       rs184649744       rs184649744       rs184649744       rs184649744       rs185477633       rs185477633       rs185477633       rs185477633       rs185477633       rs185477633       rs185552954       rs185552954       rs185552954       rs185552954       rs185552954       rs185552954       rs185614560       rs185614560       rs185614560       rs185614560       rs185614560       rs185614560       rs187586542       rs187586542       rs187586542       rs187586542       rs187586542       rs187586542       rs188698201       rs188698201       rs188698201       rs188698201       rs188698201       rs188698201       rs188903958       rs188903958       rs188903958       rs188903958       rs188903958       rs188903958       rs189216484       rs189216484       rs189216484       rs189216484       rs189216484       rs189216484       rs190017927       rs190017927       rs190017927       rs190017927       rs190017927       rs190017927       rs190023549       rs190023549       rs190023549       rs190023549       rs190023549       rs190023549       rs190710781       rs190710781       rs190710781       rs190710781       rs190710781       rs190710781       rs191730224       rs191730224       rs191730224       rs191730224       rs191730224       rs191730224       rs192487581       rs192487581       rs192487581       rs192487581       rs192487581       rs192487581       rs192529865       rs192529865       rs192529865       rs192529865       rs192529865       rs192529865       rs200071237       rs200071237       rs200071237       rs200071237       rs200071237       rs200071237       rs200162162       rs200162162       rs200162162       rs200162162       rs200162162       rs200162162       rs200613112       rs200613112       rs200613112       rs200613112       rs200613112       rs200613112       rs200805943       rs200805943       rs200805943       rs200805943       rs200805943       rs200805943       rs200855071       rs200855071       rs200855071       rs200855071       rs200855071       rs200855071       rs200932043       rs200932043       rs200932043       rs200932043       rs200932043       rs200932043       rs201990754       rs201990754       rs201990754       rs201990754       rs201990754       rs201990754       rs202047425       rs202047425       rs202047425       rs202047425       rs202047425       rs202047425       rs367851346       rs367851346       rs367851346       rs367851346       rs367851346       rs367851346       rs368206020       rs368206020       rs368206020       rs368206020       rs368206020       rs368206020       rs368255972       rs368255972       rs368255972       rs368255972       rs368255972       rs368255972       rs369030662       rs369030662       rs369030662       rs369030662       rs369030662       rs369030662       rs369457101       rs369457101       rs369457101       rs369457101       rs369457101       rs369457101       rs370403479       rs370403479       rs370403479       rs370403479       rs370403479       rs370403479       rs370519646       rs370519646       rs370519646       rs370519646       rs370519646       rs370519646       rs371047930       rs371047930       rs371047930       rs371047930       rs371047930       rs371047930       rs371722539       rs371722539       rs371722539       rs371722539       rs371722539       rs371722539       rs372824730       rs374596465       rs374596465       rs374596465       rs374596465       rs374596465       rs374596465       rs374714373       rs374714373       rs374714373       rs374714373       rs374714373       rs374714373       rs376483694       rs376483694       rs376483694       rs376483694       rs376483694       rs376483694       rs376563950       rs376563950       rs376563950       rs376563950       rs376563950       rs376563950       rs377206649       rs377206649       rs377206649       rs377206649       rs377206649       rs377206649       rs527817194       rs527817194       rs527817194       rs527817194       rs527817194       rs527817194       rs529954769       rs529954769       rs529954769       rs529954769       rs529954769       rs529954769       rs530308937       rs530308937       rs530308937       rs530308937       rs530308937       rs530308937       rs531384426       rs531384426       rs531384426       rs531384426       rs531384426       rs531384426       rs531721066       rs531721066       rs531721066       rs531721066       rs531721066       rs531721066       rs531742356       rs531742356       rs531742356       rs531742356       rs531742356       rs531742356       rs533173259       rs533173259       rs533173259       rs533173259       rs533173259       rs533173259       rs533903086       rs533903086       rs533903086       rs533903086       rs533903086       rs533903086       rs534826593       rs534826593       rs534826593       rs534826593       rs534826593       rs534826593       rs536171941       rs536171941       rs536171941       rs536171941       rs536171941       rs536171941       rs537817740       rs537817740       rs537817740       rs537817740       rs537817740       rs537817740       rs538846208       rs541396636       rs542496980       rs542914466       rs543110259       rs543397407       rs543531789       rs544479383       rs545206260       rs547085846       rs547551704       rs548199815       rs549808842       rs553640096       rs556227148       rs556489768       rs559262190       rs559501227       rs559774209       rs559993306       rs561428751       rs561758897       rs562628353       rs563828791       rs564950528       rs565951140       rs566287666       rs567291419       rs567673334       rs571646967       rs572215071       rs573821953       rs575047532       rs576973892       rs577972420       rs745377591       rs745474870       rs745536091       rs745581792       rs745822120       rs746102369       rs746428273       rs746520732       rs746539195       rs746946835       rs747425422       rs747879283       rs748101333       rs748321556       rs748684599       rs748792242       rs749422022       rs749530214       rs749827933       rs750742540       rs750948345       rs751502322       rs751730893       rs752021250       rs752066981       rs752239812       rs752714057       rs752976520       rs753441932       rs753881781       rs754185978       rs754237251       rs754458303       rs754866440       rs755007068       rs755734452       rs756099401       rs756309139       rs757111938       rs757414577       rs757593776       rs757676915       rs757866741       rs758014733       rs758048415       rs758323479       rs758360049       rs758948722       rs759076922       rs759432176       rs759595686       rs759958730       rs760448797       rs760456108       rs760517350       rs760687989       rs760777117       rs760976029       rs761447254       rs761540679       rs762494888       rs762727255       rs763238488       rs763987061       rs764088373       rs764243198       rs764342337       rs764628384       rs764724764       rs764975742       rs765029010       rs765683094       rs766106519       rs766411797       rs766541025       rs766756688       rs767324554       rs767486256       rs767746795       rs767750561       rs767909273       rs768410592       rs768731948       rs768865769       rs769188410       rs769300329       rs769672481       rs769724579       rs769778405       rs770235283       rs770488240       rs770758691       rs770938940       rs771204524       rs771363300       rs771629814       rs771657982       rs771871485       rs771988459       rs772215997       rs772575123       rs773080278       rs773204869       rs773280782       rs773547790       rs773567883       rs774182160       rs774225441       rs774751950       rs774781507       rs775235423       rs775285407       rs775544225       rs775803985       rs775874705       rs776266089       rs776750077       rs777100962       rs777277310       rs777409889       rs777940275       rs778012075       rs778413782       rs778733486       rs778824737       rs779414517       rs779649500       rs780187645       rs780200791       rs780881593       rs781255782       rs781418325       rs781443488      

基因表达

基因表达

AIF1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GATGAGATCAACAAGCAATTCC
58
TTTGAAGCCTTCCAGTTTGG
59
ATCAACAAGCAATTCCTAGACG
59
TCGCCATTTCCATTAAGGTC
58
GCGATATTGATATCATGTCCCTG
59
CAGGGTAGCTGAACGTCTC
60
TCAACAAGCAATTCCTAGACG
59
TCGCCATTTCCATTAAGGTC
58
GCGATATTGATATCATGTCCCTG
59
AAGTCAGGGTAGCTGAACG
59
GGCGATATTGATATCATGTCCC
59
CAGGGTAGCTGAACGTCTC
60

转录因子

转录因子

      尚未收录相关数据

基因本体信息

AIF1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

AIF1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0001774
P55008(UniProtKB)
NAS
GO:0001891
P55008(UniProtKB)
ISS
GO:0001934
P55008(UniProtKB)
IEA
GO:0003674
P55008(UniProtKB)
ND
GO:0005509
P55008(UniProtKB)
ISS
GO:0005634
P55008(UniProtKB)
ISS
GO:0005634
P55008(UniProtKB)
IDA
GO:0005737
P55008(UniProtKB)
ISS
GO:0005829
P55008(UniProtKB)
IDA
GO:0006911
P55008(UniProtKB)
ISS
GO:0006954
P55008(UniProtKB)
ISS
GO:0006954
P55008(UniProtKB)
NAS
GO:0010629
P55008(UniProtKB)
IEA
GO:0014739
P55008(UniProtKB)
IEA
GO:0016601
P55008(UniProtKB)
ISS
GO:0030027
P55008(UniProtKB)
ISS
GO:0030041
P55008(UniProtKB)
IDA
GO:0031668
P55008(UniProtKB)
IEA
GO:0032870
P55008(UniProtKB)
IEA
GO:0042102
P55008(UniProtKB)
IDA
GO:0043066
P55008(UniProtKB)
IEA
GO:0043204
P55008(UniProtKB)
IEA
GO:0045429
P55008(UniProtKB)
IEA
GO:0048471
P55008(UniProtKB)
IDA
GO:0048661
P55008(UniProtKB)
IDA
GO:0048661
P55008(UniProtKB)
IDA
GO:0048662
P55008(UniProtKB)
IDA
GO:0048662
P55008(UniProtKB)
IDA
GO:0048678
P55008(UniProtKB)
IEA
GO:0051015
P55008(UniProtKB)
IDA
GO:0051015
P55008(UniProtKB)
IDA
GO:0051017
P55008(UniProtKB)
IDA
GO:0051384
P55008(UniProtKB)
IEA
GO:0051602
P55008(UniProtKB)
IEA
GO:0071315
P55008(UniProtKB)
IEA
GO:0071346
P55008(UniProtKB)
ISS
GO:0071346
P55008(UniProtKB)
IEP
GO:0071447
P55008(UniProtKB)
IEA
GO:0071672
P55008(UniProtKB)
IDA
GO:0071673
P55008(UniProtKB)
IDA
GO:0090026
P55008(UniProtKB)
IDA
GO:0097178
P55008(UniProtKB)
ISS
GO:0097178
P55008(UniProtKB)
NAS
GO:1900087
P55008(UniProtKB)
IDA
GO:1900087
P55008(UniProtKB)
IDA
GO:2000406
P55008(UniProtKB)
IDA
GO:0005884
P55008(UniProtKB)
IDA
GO:0032587
P55008(UniProtKB)
IDA
GO:0005509
Q5STX8(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控AIF1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Parkinson Disease 0.12 1 0 CTD_human
Lewy Body Disease 0.12 1 0 CTD_human
Diabetes Mellitus, Insulin-Dependent 0.08554839 4 0 BeFree_GAD_RGD
Experimental Autoimmune Encephalomyelitis 0.080542884 3 0 BeFree_RGD
Neuritis, Autoimmune, Experimental 0.080271442 2 0 BeFree_RGD
Brain Ischemia 0.08 1 0 RGD
Cerebral Palsy 0.08 1 0 RGD
Glomerulonephritis 0.08 1 0 RGD
Hyperalgesia 0.08 0 0 RGD
Inflammation 0.08 1 0 RGD
Meningoencephalitis 0.08 1 0 RGD
Pain 0.08 1 0 RGD
Reperfusion Injury 0.08 1 0 RGD
Seizures 0.08 1 0 RGD
Status Epilepticus 0.08 1 0 RGD
Motor Neuron Disease 0.08 1 0 RGD
Alcohol-Induced Disorders, Nervous System 0.08 1 0 RGD
Brain Infarction 0.08 1 0 RGD
Hypoxia-Ischemia, Brain 0.08 1 0 RGD
Systemic Scleroderma 0.014264324 6 0 BeFree_GAD_LHGDN
Rheumatoid Arthritis 0.008544182 4 0 BeFree_GAD_LHGDN
Arteriosclerosis 0.003538676 3 0 BeFree_LHGDN
Creutzfeldt-Jakob disease 0.002995792 1 0 BeFree_LHGDN
Nephritis 0.00272435 1 0 LHGDN
Mammary Neoplasms 0.00272435 1 0 LHGDN
Alzheimer's Disease 0.002638474 2 0 BeFree_GAD
Lymphoma, Non-Hodgkin 0.002638474 2 3 BeFree_GAD
Age related macular degeneration 0.002638474 1 1 BeFree_GAD
Spontaneous abortion 0.002367032 1 0 GAD
Lupus Erythematosus, Systemic 0.002367032 1 0 GAD
Malaria 0.002367032 1 0 GAD
Multiple Sclerosis 0.002367032 1 1 GAD
Degenerative polyarthritis 0.002367032 1 0 GAD
Atherosclerosis 0.000814326 3 0 BeFree
Amyotrophic Lateral Sclerosis 0.000542884 2 0 BeFree
Autoimmune Diseases 0.000542884 2 0 BeFree
Cystic Fibrosis 0.000542884 2 0 BeFree
Glioma 0.000542884 2 0 BeFree
Uveitis 0.000542884 2 0 BeFree
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating 0.000542884 2 0 BeFree
Astrocytoma 0.000271442 1 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Endometriosis 0.000271442 1 0 BeFree
Exanthema 0.000271442 1 0 BeFree
Glioblastoma 0.000271442 1 0 BeFree
Herpes Simplex Infections 0.000271442 1 0 BeFree
Immune System Diseases 0.000271442 1 0 BeFree
Lymphoma, Follicular 0.000271442 1 3 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Neuritis 0.000271442 1 0 BeFree
Obesity 0.000271442 1 0 BeFree
Lymphoma, Large-Cell, Follicular 0.000271442 1 3 BeFree
Synovial Cyst 0.000271442 1 0 BeFree
gliosarcoma 0.000271442 1 0 BeFree
Senile Plaques 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Spots on skin 0.000271442 1 0 BeFree
Myxoid cyst 0.000271442 1 0 BeFree
Creutzfeldt-Jakob Disease, Sporadic 0.000271442 1 0 BeFree
Vasculitic neuropathy 0.000271442 1 0 BeFree
Plaque, Amyloid 0.000271442 1 0 BeFree
Limb ischemia 0.000271442 1 0 BeFree

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