Immune escape mechanisms as a guide for cancer immunotherapy.
作者:
Beatty(Gregory L),Gladney(Whitney L)
状态:
发布时间2015-02-18
, 更新时间 2016-12-06
期刊:
Clin Cancer Res
摘要:
Immunotherapy has demonstrated impressive outcomes for some patients with cancer. However, selecting patients who are most likely to respond to immunotherapy remains a clinical challenge. Here, we discuss immune escape mechanisms exploited by cancer and present strategies for applying this knowledge to improving the efficacy of cancer immunotherapy.