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题目:: Two genetic hits (more or less) to cancer.
作者:: Knudson(A G)
状态:: 发布时间2002-03-21 , 更新时间 2005-11-16
期刊:: Nat Rev Cancer
摘要:: Most cancers have many chromosomal abnormalities, both in number and in structure, whereas some show only a single aberration. In the era before molecular biology, cancer researchers, studying both human and animal cancers, proposed that a small number of events was needed for carcinogenesis. Evidence from the recent molecular era also indicates that cancers can arise from small numbers of events that affect common cell birth and death processes.
语言:: eng
DOI:: 10.1038/35101031

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