HLA-C (major histocompatibility complex, class I, C)

基因基本信息

基因基本信息

symbol:
HLA-C
locus group:
protein-coding gene
location:
6p21.33
gene_family:
Histocompatibility complex|C1-set domain containing
alias symbol:
None
alias name:
None
entrez id:
3107
ensembl gene id:
ENSG00000204525
ucsc gene id:
uc003nsy.4
refseq accession:
NM_002117
hgnc_id:
HGNC:4933
approved reserved:
1986-01-01

基因染色体位置

基因染色体位置

6p21.33
基因染色体位置图

基因简述

基因简述

HLA-C是人类白细胞抗原（HLA）基因家族的重要成员，属于主要组织相容性复合体（MHC）I类基因家族。HLA基因家族编码的蛋白质在免疫系统中起关键作用，主要负责抗原呈递，帮助免疫系统识别外来病原体和异常细胞。HLA-C基因位于人类第6号染色体短臂上，其编码的HLA-C蛋白是一种细胞表面糖蛋白，主要表达于几乎所有有核细胞表面。HLA-C蛋白的主要功能是将内源性抗原肽段呈递给CD8+ T细胞，从而启动细胞免疫应答。HLA-C在自然杀伤（NK）细胞的调控中也发挥重要作用，通过与NK细胞表面的杀伤细胞免疫球蛋白样受体（KIR）相互作用，调节NK细胞的活性。HLA-C基因具有高度多态性，不同等位基因可能导致个体对某些疾病的易感性或抵抗性差异。HLA-C基因突变可能影响其蛋白表达或功能，导致免疫应答异常，与多种自身免疫性疾病、感染性疾病和癌症相关。例如，某些HLA-C等位基因与类风湿关节炎、银屑病、艾滋病进展速度等疾病密切相关。HLA-C过表达可能导致过度免疫激活，增加自身免疫疾病风险；而表达降低则可能削弱抗病毒和抗肿瘤免疫监视功能。HLA-C的表达水平还影响器官移植中的排斥反应，是移植配型的重要考量因素。HLA基因家族的共同特点是编码细胞表面的糖蛋白，参与抗原呈递和免疫调节，具有高度多态性，在个体间呈现遗传多样性，对疾病易感性和药物反应产生重要影响。HLA-C作为该家族成员，既具有这些共性特征，又在NK细胞调控等方面表现出独特功能。

None

无

OMIM数据库中对HLA-C基因的介绍     Wikipedia数据库中对HLA-C基因的介绍

基因序列

基因序列

HLA-C基因的碱基序列：[NCBI]
Loading Gene Browser...

基因突变

基因突变

HLA-C基因的碱基突变：           仅显示部分snp
rs1094       rs1094       rs697743       rs707908       rs707911       rs713032       rs1049281       rs1049281       rs1049579       rs1049579       rs1049650       rs1049663       rs1049668       rs1049709       rs1049724       rs1049853       rs1050105      

基因表达

基因表达

HLA-C基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向Tm值
反向引物序列
反向Tm值
评分
GCTACTACAACCAGAGCGA
59
TAATCCTTGCCGTCGTAGG
59
AGATACCTGGAGAACGGGA
59
GAAGGTTCCATCTCCTGCT
59
GTAGGAGGAAGAGCTCAGG
59
CTGTCTCAGGCTTTACAAGTG
59
GTAGGAGGAAGAGCTCAGG
59
CTGTCTCAGGCTTTACAAGTG
59
TGTGTAGGAGGAAGAGCTC
58
TGTCTCAGGCTTTACAAGTG
58
TCATCACTTGTAAAGCCTGAG
58
TGAAGTCACAAAGGAGAGGT
59
GTAGGAGGAAGAGCTCAGG
59
CTGTCTCAGGCTTTACAAGTG
59
GTAGGAGGAAGAGCTCAGG
59
CTGTCTCAGGCTTTACAAGTG
59
CTACAACCAGAGCGAGGAC
60
ATGTAATCCTTGCCGTCGT
60
CCATGAGGTATTTCGACACC
59
TAGCCCACTGAGATGAAGC
59

转录因子

转录因子

转录因子
影响基因
影响类型
参考文献链接（PubMed）
CIITA
HLA-C
Activation
11053628
HIVEP2
HLA-C
Unknown
1409593
MYC
HLA-C
Activation
8206526
MYCN
HLA-C
Unknown
8895520

基因本体信息

HLA-C基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 质膜
  • 细胞质
  • 细胞外
  • 高尔基体
  • 囊泡
  • 细胞骨架
  • 内质网
  • 细胞核
  • 内体
  • 溶酶体
  • 线粒体

HLA-C基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0002474
A0A0G2JH50 (UniProtKB)
IEA
GO:0006955
A0A0G2JH50 (UniProtKB)
IEA
GO:0016021
A0A0G2JH50 (UniProtKB)
IEA
GO:0042605
A0A0G2JH50 (UniProtKB)
IEA
GO:0042612
A0A0G2JH50 (UniProtKB)
IEA
GO:0002474
A0A0G2JIF0 (UniProtKB)
IEA
GO:0006955
A0A0G2JIF0 (UniProtKB)
IEA
GO:0016021
A0A0G2JIF0 (UniProtKB)
IEA
GO:0042605
A0A0G2JIF0 (UniProtKB)
IEA
GO:0042612
A0A0G2JIF0 (UniProtKB)
IEA
GO:0006955
A0A0G2JKJ1 (UniProtKB)
IEA
GO:0006955
A0A0G2JPB1 (UniProtKB)
IEA
GO:0019882
A0A0G2JPB1 (UniProtKB)
IEA
GO:0006955
A0A0G2JPT2 (UniProtKB)
IEA
GO:0019882
A0A0G2JPT2 (UniProtKB)
IEA
GO:0002474
A0A140T912 (UniProtKB)
IEA
GO:0006955
A0A140T912 (UniProtKB)
IEA
GO:0042605
A0A140T912 (UniProtKB)
IEA
GO:0042612
A0A140T912 (UniProtKB)
IEA
GO:0002474
A0A140T921 (UniProtKB)
IEA
GO:0006955
A0A140T921 (UniProtKB)
IEA
GO:0042605
A0A140T921 (UniProtKB)
IEA
GO:0042612
A0A140T921 (UniProtKB)
IEA
GO:0002474
A0A140T930 (UniProtKB)
IEA
GO:0006955
A0A140T930 (UniProtKB)
IEA
GO:0042605
A0A140T930 (UniProtKB)
IEA
GO:0042612
A0A140T930 (UniProtKB)
IEA
GO:0002474
A0A140T937 (UniProtKB)
IEA
GO:0006955
A0A140T937 (UniProtKB)
IEA
GO:0042605
A0A140T937 (UniProtKB)
IEA
GO:0042612
A0A140T937 (UniProtKB)
IEA
GO:0002474
A0A140T942 (UniProtKB)
IEA
GO:0006955
A0A140T942 (UniProtKB)
IEA
GO:0042605
A0A140T942 (UniProtKB)
IEA
GO:0042612
A0A140T942 (UniProtKB)
IEA
GO:0002474
A0A140T962 (UniProtKB)
IEA
GO:0006955
A0A140T962 (UniProtKB)
IEA
GO:0042605
A0A140T962 (UniProtKB)
IEA
GO:0042612
A0A140T962 (UniProtKB)
IEA
GO:0002474
A0A140T9B3 (UniProtKB)
IEA
GO:0006955
A0A140T9B3 (UniProtKB)
IEA
GO:0042605
A0A140T9B3 (UniProtKB)
IEA
GO:0042612
A0A140T9B3 (UniProtKB)
IEA
GO:0002474
A0A140T9E1 (UniProtKB)
IEA
GO:0006955
A0A140T9E1 (UniProtKB)
IEA
GO:0042605
A0A140T9E1 (UniProtKB)
IEA
GO:0042612
A0A140T9E1 (UniProtKB)
IEA
GO:0002474
A0A140T9H5 (UniProtKB)
IEA
GO:0006955
A0A140T9H5 (UniProtKB)
IEA
GO:0042605
A0A140T9H5 (UniProtKB)
IEA
GO:0042612
A0A140T9H5 (UniProtKB)
IEA
GO:0002474
A0A140T9J9 (UniProtKB)
IEA
GO:0006955
A0A140T9J9 (UniProtKB)
IEA
GO:0042605
A0A140T9J9 (UniProtKB)
IEA
GO:0042612
A0A140T9J9 (UniProtKB)
IEA
GO:0002474
A0A140T9L3 (UniProtKB)
IEA
GO:0006955
A0A140T9L3 (UniProtKB)
IEA
GO:0042605
A0A140T9L3 (UniProtKB)
IEA
GO:0042612
A0A140T9L3 (UniProtKB)
IEA
GO:0002474
A0A140T9M0 (UniProtKB)
IEA
GO:0006955
A0A140T9M0 (UniProtKB)
IEA
GO:0042605
A0A140T9M0 (UniProtKB)
IEA
GO:0042612
A0A140T9M0 (UniProtKB)
IEA
GO:0002474
A0A140T9M5 (UniProtKB)
IEA
GO:0006955
A0A140T9M5 (UniProtKB)
IEA
GO:0042605
A0A140T9M5 (UniProtKB)
IEA
GO:0042612
A0A140T9M5 (UniProtKB)
IEA
GO:0002474
A0A140T9Q4 (UniProtKB)
IEA
GO:0006955
A0A140T9Q4 (UniProtKB)
IEA
GO:0042605
A0A140T9Q4 (UniProtKB)
IEA
GO:0042612
A0A140T9Q4 (UniProtKB)
IEA
GO:0002474
A0A140T9S7 (UniProtKB)
IEA
GO:0006955
A0A140T9S7 (UniProtKB)
IEA
GO:0042605
A0A140T9S7 (UniProtKB)
IEA
GO:0042612
A0A140T9S7 (UniProtKB)
IEA
GO:0002474
A0A140T9T1 (UniProtKB)
IEA
GO:0006955
A0A140T9T1 (UniProtKB)
IEA
GO:0042605
A0A140T9T1 (UniProtKB)
IEA
GO:0042612
A0A140T9T1 (UniProtKB)
IEA
GO:0002474
A0A140T9U0 (UniProtKB)
IEA
GO:0006955
A0A140T9U0 (UniProtKB)
IEA
GO:0042605
A0A140T9U0 (UniProtKB)
IEA
GO:0042612
A0A140T9U0 (UniProtKB)
IEA
GO:0002474
A0A140T9U8 (UniProtKB)
IEA
GO:0006955
A0A140T9U8 (UniProtKB)
IEA
GO:0042605
A0A140T9U8 (UniProtKB)
IEA
GO:0042612
A0A140T9U8 (UniProtKB)
IEA
GO:0002474
A0A140T9W2 (UniProtKB)
IEA
GO:0006955
A0A140T9W2 (UniProtKB)
IEA
GO:0042605
A0A140T9W2 (UniProtKB)
IEA
GO:0042612
A0A140T9W2 (UniProtKB)
IEA
GO:0006955
A0A140T9Z4 (UniProtKB)
IEA
GO:0006955
A0A140T9Z7 (UniProtKB)
IEA
GO:0006955
A0A140TA03 (UniProtKB)
IEA
GO:0002474
A0A140TA05 (UniProtKB)
IEA
GO:0006955
A0A140TA05 (UniProtKB)
IEA
GO:0042605
A0A140TA05 (UniProtKB)
IEA
GO:0042612
A0A140TA05 (UniProtKB)
IEA
GO:0006955
A0A140TA12 (UniProtKB)
IEA
GO:0002474
A0A140TA19 (UniProtKB)
IEA
GO:0006955
A0A140TA19 (UniProtKB)
IEA
GO:0042605
A0A140TA19 (UniProtKB)
IEA
GO:0042612
A0A140TA19 (UniProtKB)
IEA
GO:0002474
A2AEA2 (UniProtKB)
IEA
GO:0006955
A2AEA2 (UniProtKB)
IEA
GO:0016021
A2AEA2 (UniProtKB)
IEA
GO:0042605
A2AEA2 (UniProtKB)
IEA
GO:0042612
A2AEA2 (UniProtKB)
IEA
GO:0002474
A2BF26 (UniProtKB)
IEA
GO:0006955
A2BF26 (UniProtKB)
IEA
GO:0016021
A2BF26 (UniProtKB)
IEA
GO:0042605
A2BF26 (UniProtKB)
IEA
GO:0042612
A2BF26 (UniProtKB)
IEA
GO:0006955
F8W9Z8 (UniProtKB)
IEA
GO:0002474
O19617 (UniProtKB)
IEA
GO:0006955
O19617 (UniProtKB)
IEA
GO:0016021
O19617 (UniProtKB)
IEA
GO:0042605
O19617 (UniProtKB)
IEA
GO:0042612
O19617 (UniProtKB)
IEA
GO:0000139
P04222 (UniProtKB)
TAS
GO:0000139
P04222 (UniProtKB)
TAS
GO:0002474
P04222 (UniProtKB)
TAS
GO:0002479
P04222 (UniProtKB)
TAS
GO:0002480
P04222 (UniProtKB)
TAS
GO:0005783
P04222 (UniProtKB)
ISS
GO:0005794
P04222 (UniProtKB)
ISS
GO:0005886
P04222 (UniProtKB)
TAS
GO:0005886
P04222 (UniProtKB)
TAS
GO:0005886
P04222 (UniProtKB)
TAS
GO:0005886
P04222 (UniProtKB)
TAS
GO:0005886
P04222 (UniProtKB)
TAS
GO:0005886
P04222 (UniProtKB)
TAS
GO:0005886
P04222 (UniProtKB)
TAS
GO:0005886
P04222 (UniProtKB)
TAS
GO:0005886
P04222 (UniProtKB)
TAS
GO:0009986
P04222 (UniProtKB)
IDA
GO:0012507
P04222 (UniProtKB)
TAS
GO:0012507
P04222 (UniProtKB)
TAS
GO:0012507
P04222 (UniProtKB)
TAS
GO:0016032
P04222 (UniProtKB)
IEA
GO:0030670
P04222 (UniProtKB)
TAS
GO:0031901
P04222 (UniProtKB)
TAS
GO:0031901
P04222 (UniProtKB)
TAS
GO:0031901
P04222 (UniProtKB)
TAS
GO:0042605
P04222 (UniProtKB)
ISS
GO:0042612
P04222 (UniProtKB)
ISS
GO:0045087
P04222 (UniProtKB)
TAS
GO:0046977
P04222 (UniProtKB)
IDA
GO:0050776
P04222 (UniProtKB)
TAS
GO:0060333
P04222 (UniProtKB)
TAS
GO:0060337
P04222 (UniProtKB)
TAS
GO:0071556
P04222 (UniProtKB)
TAS
GO:0071556
P04222 (UniProtKB)
TAS
GO:0071556
P04222 (UniProtKB)
TAS
GO:0071556
P04222 (UniProtKB)
TAS
GO:0071556
P04222 (UniProtKB)
TAS
GO:0071556
P04222 (UniProtKB)
TAS
GO:0071556
P04222 (UniProtKB)
TAS
GO:0071556
P04222 (UniProtKB)
TAS
GO:0071556
P04222 (UniProtKB)
TAS
GO:0071556
P04222 (UniProtKB)
TAS
GO:0000139
P10321 (UniProtKB)
TAS
GO:0000139
P10321 (UniProtKB)
TAS
GO:0002474
P10321 (UniProtKB)
TAS
GO:0002479
P10321 (UniProtKB)
TAS
GO:0002480
P10321 (UniProtKB)
TAS
GO:0005783
P10321 (UniProtKB)
ISS
GO:0005794
P10321 (UniProtKB)
ISS
GO:0005886
P10321 (UniProtKB)
TAS
GO:0005886
P10321 (UniProtKB)
TAS
GO:0005886
P10321 (UniProtKB)
TAS
GO:0005886
P10321 (UniProtKB)
TAS
GO:0009986
P10321 (UniProtKB)
IDA
GO:0012507
P10321 (UniProtKB)
TAS
GO:0012507
P10321 (UniProtKB)
TAS
GO:0012507
P10321 (UniProtKB)
TAS
GO:0016032
P10321 (UniProtKB)
IEA
GO:0030670
P10321 (UniProtKB)
TAS
GO:0031901
P10321 (UniProtKB)
TAS
GO:0031901
P10321 (UniProtKB)
TAS
GO:0031901
P10321 (UniProtKB)
TAS
GO:0042605
P10321 (UniProtKB)
ISS
GO:0042612
P10321 (UniProtKB)
ISS
GO:0050776
P10321 (UniProtKB)
TAS
GO:0060333
P10321 (UniProtKB)
TAS
GO:0060337
P10321 (UniProtKB)
TAS
GO:0070062
P10321 (UniProtKB)
IDA
GO:0071556
P10321 (UniProtKB)
TAS
GO:0071556
P10321 (UniProtKB)
TAS
GO:0071556
P10321 (UniProtKB)
TAS
GO:0071556
P10321 (UniProtKB)
TAS
GO:0071556
P10321 (UniProtKB)
TAS
GO:0071556
P10321 (UniProtKB)
TAS
GO:0071556
P10321 (UniProtKB)
TAS
GO:0071556
P10321 (UniProtKB)
TAS
GO:0071556
P10321 (UniProtKB)
TAS
GO:0071556
P10321 (UniProtKB)
TAS
GO:0000139
P30499 (UniProtKB)
TAS
GO:0000139
P30499 (UniProtKB)
TAS
GO:0002474
P30499 (UniProtKB)
TAS
GO:0002479
P30499 (UniProtKB)
TAS
GO:0002480
P30499 (UniProtKB)
TAS
GO:0002486
P30499 (UniProtKB)
IDA
GO:0005783
P30499 (UniProtKB)
ISS
GO:0005794
P30499 (UniProtKB)
ISS
GO:0005886
P30499 (UniProtKB)
TAS
GO:0005886
P30499 (UniProtKB)
TAS
GO:0005886
P30499 (UniProtKB)
TAS
GO:0005886
P30499 (UniProtKB)
TAS
GO:0005887
P30499 (UniProtKB)
NAS
GO:0006955
P30499 (UniProtKB)
NAS
GO:0009986
P30499 (UniProtKB)
IDA
GO:0012507
P30499 (UniProtKB)
TAS
GO:0012507
P30499 (UniProtKB)
TAS
GO:0012507
P30499 (UniProtKB)
TAS
GO:0016032
P30499 (UniProtKB)
IEA
GO:0030670
P30499 (UniProtKB)
TAS
GO:0031901
P30499 (UniProtKB)
TAS
GO:0031901
P30499 (UniProtKB)
TAS
GO:0031901
P30499 (UniProtKB)
TAS
GO:0042605
P30499 (UniProtKB)
IDA
GO:0042612
P30499 (UniProtKB)
IDA
GO:0046977
P30499 (UniProtKB)
IDA
GO:0050776
P30499 (UniProtKB)
TAS
GO:0060333
P30499 (UniProtKB)
TAS
GO:0060337
P30499 (UniProtKB)
TAS
GO:0071556
P30499 (UniProtKB)
TAS
GO:0071556
P30499 (UniProtKB)
TAS
GO:0071556
P30499 (UniProtKB)
TAS
GO:0071556
P30499 (UniProtKB)
TAS
GO:0071556
P30499 (UniProtKB)
TAS
GO:0071556
P30499 (UniProtKB)
TAS
GO:0071556
P30499 (UniProtKB)
TAS
GO:0071556
P30499 (UniProtKB)
TAS
GO:0071556
P30499 (UniProtKB)
TAS
GO:0071556
P30499 (UniProtKB)
TAS
GO:0000139
P30501 (UniProtKB)
TAS
GO:0000139
P30501 (UniProtKB)
TAS
GO:0002474
P30501 (UniProtKB)
TAS
GO:0002479
P30501 (UniProtKB)
TAS
GO:0002480
P30501 (UniProtKB)
TAS
GO:0005783
P30501 (UniProtKB)
ISS
GO:0005794
P30501 (UniProtKB)
ISS
GO:0005886
P30501 (UniProtKB)
TAS
GO:0005886
P30501 (UniProtKB)
TAS
GO:0005886
P30501 (UniProtKB)
TAS
GO:0005886
P30501 (UniProtKB)
TAS
GO:0005887
P30501 (UniProtKB)
NAS
GO:0006955
P30501 (UniProtKB)
NAS
GO:0009986
P30501 (UniProtKB)
ISS
GO:0012507
P30501 (UniProtKB)
TAS
GO:0012507
P30501 (UniProtKB)
TAS
GO:0012507
P30501 (UniProtKB)
TAS
GO:0016032
P30501 (UniProtKB)
IEA
GO:0030670
P30501 (UniProtKB)
TAS
GO:0031901
P30501 (UniProtKB)
TAS
GO:0031901
P30501 (UniProtKB)
TAS
GO:0031901
P30501 (UniProtKB)
TAS
GO:0042605
P30501 (UniProtKB)
ISS
GO:0042612
P30501 (UniProtKB)
ISS
GO:0046977
P30501 (UniProtKB)
IDA
GO:0050776
P30501 (UniProtKB)
TAS
GO:0060333
P30501 (UniProtKB)
TAS
GO:0060337
P30501 (UniProtKB)
TAS
GO:0071556
P30501 (UniProtKB)
TAS
GO:0071556
P30501 (UniProtKB)
TAS
GO:0071556
P30501 (UniProtKB)
TAS
GO:0071556
P30501 (UniProtKB)
TAS
GO:0071556
P30501 (UniProtKB)
TAS
GO:0071556
P30501 (UniProtKB)
TAS
GO:0071556
P30501 (UniProtKB)
TAS
GO:0071556
P30501 (UniProtKB)
TAS
GO:0071556
P30501 (UniProtKB)
TAS
GO:0071556
P30501 (UniProtKB)
TAS
GO:0000139
P30504 (UniProtKB)
TAS
GO:0000139
P30504 (UniProtKB)
TAS
GO:0002474
P30504 (UniProtKB)
TAS
GO:0002479
P30504 (UniProtKB)
TAS
GO:0002480
P30504 (UniProtKB)
TAS
GO:0005783
P30504 (UniProtKB)
ISS
GO:0005794
P30504 (UniProtKB)
ISS
GO:0005886
P30504 (UniProtKB)
TAS
GO:0005886
P30504 (UniProtKB)
TAS
GO:0005886
P30504 (UniProtKB)
TAS
GO:0005886
P30504 (UniProtKB)
TAS
GO:0005886
P30504 (UniProtKB)
TAS
GO:0005886
P30504 (UniProtKB)
TAS
GO:0005886
P30504 (UniProtKB)
TAS
GO:0005886
P30504 (UniProtKB)
TAS
GO:0009986
P30504 (UniProtKB)
ISS
GO:0012507
P30504 (UniProtKB)
TAS
GO:0012507
P30504 (UniProtKB)
TAS
GO:0012507
P30504 (UniProtKB)
TAS
GO:0016032
P30504 (UniProtKB)
IEA
GO:0030670
P30504 (UniProtKB)
TAS
GO:0031901
P30504 (UniProtKB)
TAS
GO:0031901
P30504 (UniProtKB)
TAS
GO:0031901
P30504 (UniProtKB)
TAS
GO:0042605
P30504 (UniProtKB)
ISS
GO:0042612
P30504 (UniProtKB)
ISS
GO:0045087
P30504 (UniProtKB)
TAS
GO:0046977
P30504 (UniProtKB)
IDA
GO:0046977
P30504 (UniProtKB)
IDA
GO:0050776
P30504 (UniProtKB)
TAS
GO:0060333
P30504 (UniProtKB)
TAS
GO:0060337
P30504 (UniProtKB)
TAS
GO:0071556
P30504 (UniProtKB)
TAS
GO:0071556
P30504 (UniProtKB)
TAS
GO:0071556
P30504 (UniProtKB)
TAS
GO:0071556
P30504 (UniProtKB)
TAS
GO:0071556
P30504 (UniProtKB)
TAS
GO:0071556
P30504 (UniProtKB)
TAS
GO:0071556
P30504 (UniProtKB)
TAS
GO:0071556
P30504 (UniProtKB)
TAS
GO:0071556
P30504 (UniProtKB)
TAS
GO:0071556
P30504 (UniProtKB)
TAS
GO:0000139
P30505 (UniProtKB)
TAS
GO:0000139
P30505 (UniProtKB)
TAS
GO:0002474
P30505 (UniProtKB)
TAS
GO:0002479
P30505 (UniProtKB)
TAS
GO:0002480
P30505 (UniProtKB)
TAS
GO:0005783
P30505 (UniProtKB)
ISS
GO:0005794
P30505 (UniProtKB)
ISS
GO:0005886
P30505 (UniProtKB)
TAS
GO:0005886
P30505 (UniProtKB)
TAS
GO:0005886
P30505 (UniProtKB)
TAS
GO:0005886
P30505 (UniProtKB)
TAS
GO:0009986
P30505 (UniProtKB)
ISS
GO:0012507
P30505 (UniProtKB)
TAS
GO:0012507
P30505 (UniProtKB)
TAS
GO:0012507
P30505 (UniProtKB)
TAS
GO:0016032
P30505 (UniProtKB)
IEA
GO:0030670
P30505 (UniProtKB)
TAS
GO:0031901
P30505 (UniProtKB)
TAS
GO:0031901
P30505 (UniProtKB)
TAS
GO:0031901
P30505 (UniProtKB)
TAS
GO:0042605
P30505 (UniProtKB)
ISS
GO:0042612
P30505 (UniProtKB)
ISS
GO:0050776
P30505 (UniProtKB)
TAS
GO:0060333
P30505 (UniProtKB)
TAS
GO:0060337
P30505 (UniProtKB)
TAS
GO:0071556
P30505 (UniProtKB)
TAS
GO:0071556
P30505 (UniProtKB)
TAS
GO:0071556
P30505 (UniProtKB)
TAS
GO:0071556
P30505 (UniProtKB)
TAS
GO:0071556
P30505 (UniProtKB)
TAS
GO:0071556
P30505 (UniProtKB)
TAS
GO:0071556
P30505 (UniProtKB)
TAS
GO:0071556
P30505 (UniProtKB)
TAS
GO:0071556
P30505 (UniProtKB)
TAS
GO:0071556
P30505 (UniProtKB)
TAS
GO:0000139
P30508 (UniProtKB)
TAS
GO:0000139
P30508 (UniProtKB)
TAS
GO:0002474
P30508 (UniProtKB)
TAS
GO:0002479
P30508 (UniProtKB)
TAS
GO:0002480
P30508 (UniProtKB)
TAS
GO:0005783
P30508 (UniProtKB)
ISS
GO:0005794
P30508 (UniProtKB)
ISS
GO:0005886
P30508 (UniProtKB)
TAS
GO:0005886
P30508 (UniProtKB)
TAS
GO:0005886
P30508 (UniProtKB)
TAS
GO:0005886
P30508 (UniProtKB)
TAS
GO:0005887
P30508 (UniProtKB)
NAS
GO:0005887
P30508 (UniProtKB)
NAS
GO:0006955
P30508 (UniProtKB)
NAS
GO:0006955
P30508 (UniProtKB)
NAS
GO:0009986
P30508 (UniProtKB)
ISS
GO:0012507
P30508 (UniProtKB)
TAS
GO:0012507
P30508 (UniProtKB)
TAS
GO:0012507
P30508 (UniProtKB)
TAS
GO:0016032
P30508 (UniProtKB)
IEA
GO:0030670
P30508 (UniProtKB)
TAS
GO:0031901
P30508 (UniProtKB)
TAS
GO:0031901
P30508 (UniProtKB)
TAS
GO:0031901
P30508 (UniProtKB)
TAS
GO:0042605
P30508 (UniProtKB)
ISS
GO:0042612
P30508 (UniProtKB)
ISS
GO:0050776
P30508 (UniProtKB)
TAS
GO:0060333
P30508 (UniProtKB)
TAS
GO:0060337
P30508 (UniProtKB)
TAS
GO:0070062
P30508 (UniProtKB)
IDA
GO:0071556
P30508 (UniProtKB)
TAS
GO:0071556
P30508 (UniProtKB)
TAS
GO:0071556
P30508 (UniProtKB)
TAS
GO:0071556
P30508 (UniProtKB)
TAS
GO:0071556
P30508 (UniProtKB)
TAS
GO:0071556
P30508 (UniProtKB)
TAS
GO:0071556
P30508 (UniProtKB)
TAS
GO:0071556
P30508 (UniProtKB)
TAS
GO:0071556
P30508 (UniProtKB)
TAS
GO:0071556
P30508 (UniProtKB)
TAS
GO:0000139
P30510 (UniProtKB)
TAS
GO:0000139
P30510 (UniProtKB)
TAS
GO:0002474
P30510 (UniProtKB)
TAS
GO:0002479
P30510 (UniProtKB)
TAS
GO:0002480
P30510 (UniProtKB)
TAS
GO:0005783
P30510 (UniProtKB)
ISS
GO:0005794
P30510 (UniProtKB)
ISS
GO:0005886
P30510 (UniProtKB)
TAS
GO:0005886
P30510 (UniProtKB)
TAS
GO:0005886
P30510 (UniProtKB)
TAS
GO:0005886
P30510 (UniProtKB)
TAS
GO:0005887
P30510 (UniProtKB)
NAS
GO:0006955
P30510 (UniProtKB)
NAS
GO:0009986
P30510 (UniProtKB)
ISS
GO:0012507
P30510 (UniProtKB)
TAS
GO:0012507
P30510 (UniProtKB)
TAS
GO:0012507
P30510 (UniProtKB)
TAS
GO:0016032
P30510 (UniProtKB)
IEA
GO:0030670
P30510 (UniProtKB)
TAS
GO:0031901
P30510 (UniProtKB)
TAS
GO:0031901
P30510 (UniProtKB)
TAS
GO:0031901
P30510 (UniProtKB)
TAS
GO:0042605
P30510 (UniProtKB)
ISS
GO:0042612
P30510 (UniProtKB)
ISS
GO:0050776
P30510 (UniProtKB)
TAS
GO:0060333
P30510 (UniProtKB)
TAS
GO:0060337
P30510 (UniProtKB)
TAS
GO:0071556
P30510 (UniProtKB)
TAS
GO:0071556
P30510 (UniProtKB)
TAS
GO:0071556
P30510 (UniProtKB)
TAS
GO:0071556
P30510 (UniProtKB)
TAS
GO:0071556
P30510 (UniProtKB)
TAS
GO:0071556
P30510 (UniProtKB)
TAS
GO:0071556
P30510 (UniProtKB)
TAS
GO:0071556
P30510 (UniProtKB)
TAS
GO:0071556
P30510 (UniProtKB)
TAS
GO:0071556
P30510 (UniProtKB)
TAS
GO:0000139
Q07000 (UniProtKB)
TAS
GO:0000139
Q07000 (UniProtKB)
TAS
GO:0002474
Q07000 (UniProtKB)
TAS
GO:0002479
Q07000 (UniProtKB)
TAS
GO:0002480
Q07000 (UniProtKB)
TAS
GO:0005783
Q07000 (UniProtKB)
ISS
GO:0005794
Q07000 (UniProtKB)
ISS
GO:0005886
Q07000 (UniProtKB)
TAS
GO:0005886
Q07000 (UniProtKB)
TAS
GO:0005886
Q07000 (UniProtKB)
TAS
GO:0005886
Q07000 (UniProtKB)
TAS
GO:0009986
Q07000 (UniProtKB)
ISS
GO:0012507
Q07000 (UniProtKB)
TAS
GO:0012507
Q07000 (UniProtKB)
TAS
GO:0012507
Q07000 (UniProtKB)
TAS
GO:0016032
Q07000 (UniProtKB)
IEA
GO:0030670
Q07000 (UniProtKB)
TAS
GO:0031901
Q07000 (UniProtKB)
TAS
GO:0031901
Q07000 (UniProtKB)
TAS
GO:0031901
Q07000 (UniProtKB)
TAS
GO:0042605
Q07000 (UniProtKB)
ISS
GO:0042612
Q07000 (UniProtKB)
ISS
GO:0050776
Q07000 (UniProtKB)
TAS
GO:0060333
Q07000 (UniProtKB)
TAS
GO:0060337
Q07000 (UniProtKB)
TAS
GO:0071556
Q07000 (UniProtKB)
TAS
GO:0071556
Q07000 (UniProtKB)
TAS
GO:0071556
Q07000 (UniProtKB)
TAS
GO:0071556
Q07000 (UniProtKB)
TAS
GO:0071556
Q07000 (UniProtKB)
TAS
GO:0071556
Q07000 (UniProtKB)
TAS
GO:0071556
Q07000 (UniProtKB)
TAS
GO:0071556
Q07000 (UniProtKB)
TAS
GO:0071556
Q07000 (UniProtKB)
TAS
GO:0071556
Q07000 (UniProtKB)
TAS
GO:0000139
Q29865 (UniProtKB)
TAS
GO:0000139
Q29865 (UniProtKB)
TAS
GO:0002474
Q29865 (UniProtKB)
TAS
GO:0002479
Q29865 (UniProtKB)
TAS
GO:0002480
Q29865 (UniProtKB)
TAS
GO:0005783
Q29865 (UniProtKB)
ISS
GO:0005794
Q29865 (UniProtKB)
ISS
GO:0005886
Q29865 (UniProtKB)
TAS
GO:0005886
Q29865 (UniProtKB)
TAS
GO:0005886
Q29865 (UniProtKB)
TAS
GO:0005886
Q29865 (UniProtKB)
TAS
GO:0009986
Q29865 (UniProtKB)
ISS
GO:0012507
Q29865 (UniProtKB)
TAS
GO:0012507
Q29865 (UniProtKB)
TAS
GO:0012507
Q29865 (UniProtKB)
TAS
GO:0016032
Q29865 (UniProtKB)
IEA
GO:0030670
Q29865 (UniProtKB)
TAS
GO:0031901
Q29865 (UniProtKB)
TAS
GO:0031901
Q29865 (UniProtKB)
TAS
GO:0031901
Q29865 (UniProtKB)
TAS
GO:0042605
Q29865 (UniProtKB)
ISS
GO:0042612
Q29865 (UniProtKB)
ISS
GO:0050776
Q29865 (UniProtKB)
TAS
GO:0060333
Q29865 (UniProtKB)
TAS
GO:0060337
Q29865 (UniProtKB)
TAS
GO:0071556
Q29865 (UniProtKB)
TAS
GO:0071556
Q29865 (UniProtKB)
TAS
GO:0071556
Q29865 (UniProtKB)
TAS
GO:0071556
Q29865 (UniProtKB)
TAS
GO:0071556
Q29865 (UniProtKB)
TAS
GO:0071556
Q29865 (UniProtKB)
TAS
GO:0071556
Q29865 (UniProtKB)
TAS
GO:0071556
Q29865 (UniProtKB)
TAS
GO:0071556
Q29865 (UniProtKB)
TAS
GO:0071556
Q29865 (UniProtKB)
TAS
GO:0000139
Q29960 (UniProtKB)
TAS
GO:0000139
Q29960 (UniProtKB)
TAS
GO:0002474
Q29960 (UniProtKB)
TAS
GO:0002479
Q29960 (UniProtKB)
TAS
GO:0002480
Q29960 (UniProtKB)
TAS
GO:0005576
Q29960 (UniProtKB)
IEA
GO:0005783
Q29960 (UniProtKB)
ISS
GO:0005794
Q29960 (UniProtKB)
ISS
GO:0005886
Q29960 (UniProtKB)
TAS
GO:0005886
Q29960 (UniProtKB)
TAS
GO:0005886
Q29960 (UniProtKB)
TAS
GO:0005886
Q29960 (UniProtKB)
TAS
GO:0009986
Q29960 (UniProtKB)
ISS
GO:0012507
Q29960 (UniProtKB)
TAS
GO:0012507
Q29960 (UniProtKB)
TAS
GO:0012507
Q29960 (UniProtKB)
TAS
GO:0016032
Q29960 (UniProtKB)
IEA
GO:0030670
Q29960 (UniProtKB)
TAS
GO:0031901
Q29960 (UniProtKB)
TAS
GO:0031901
Q29960 (UniProtKB)
TAS
GO:0031901
Q29960 (UniProtKB)
TAS
GO:0042605
Q29960 (UniProtKB)
ISS
GO:0042612
Q29960 (UniProtKB)
ISS
GO:0050776
Q29960 (UniProtKB)
TAS
GO:0060333
Q29960 (UniProtKB)
TAS
GO:0060337
Q29960 (UniProtKB)
TAS
GO:0071556
Q29960 (UniProtKB)
TAS
GO:0071556
Q29960 (UniProtKB)
TAS
GO:0071556
Q29960 (UniProtKB)
TAS
GO:0071556
Q29960 (UniProtKB)
TAS
GO:0071556
Q29960 (UniProtKB)
TAS
GO:0071556
Q29960 (UniProtKB)
TAS
GO:0071556
Q29960 (UniProtKB)
TAS
GO:0071556
Q29960 (UniProtKB)
TAS
GO:0071556
Q29960 (UniProtKB)
TAS
GO:0071556
Q29960 (UniProtKB)
TAS
GO:0000139
Q29963 (UniProtKB)
TAS
GO:0000139
Q29963 (UniProtKB)
TAS
GO:0002474
Q29963 (UniProtKB)
TAS
GO:0002479
Q29963 (UniProtKB)
TAS
GO:0002480
Q29963 (UniProtKB)
TAS
GO:0005783
Q29963 (UniProtKB)
IDA
GO:0005794
Q29963 (UniProtKB)
IDA
GO:0005886
Q29963 (UniProtKB)
TAS
GO:0005886
Q29963 (UniProtKB)
TAS
GO:0005886
Q29963 (UniProtKB)
TAS
GO:0005886
Q29963 (UniProtKB)
TAS
GO:0009986
Q29963 (UniProtKB)
ISS
GO:0012507
Q29963 (UniProtKB)
TAS
GO:0012507
Q29963 (UniProtKB)
TAS
GO:0012507
Q29963 (UniProtKB)
TAS
GO:0016032
Q29963 (UniProtKB)
IEA
GO:0030670
Q29963 (UniProtKB)
TAS
GO:0031901
Q29963 (UniProtKB)
TAS
GO:0031901
Q29963 (UniProtKB)
TAS
GO:0031901
Q29963 (UniProtKB)
TAS
GO:0042605
Q29963 (UniProtKB)
ISS
GO:0042612
Q29963 (UniProtKB)
ISS
GO:0050776
Q29963 (UniProtKB)
TAS
GO:0060333
Q29963 (UniProtKB)
TAS
GO:0060337
Q29963 (UniProtKB)
TAS
GO:0071556
Q29963 (UniProtKB)
TAS
GO:0071556
Q29963 (UniProtKB)
TAS
GO:0071556
Q29963 (UniProtKB)
TAS
GO:0071556
Q29963 (UniProtKB)
TAS
GO:0071556
Q29963 (UniProtKB)
TAS
GO:0071556
Q29963 (UniProtKB)
TAS
GO:0071556
Q29963 (UniProtKB)
TAS
GO:0071556
Q29963 (UniProtKB)
TAS
GO:0071556
Q29963 (UniProtKB)
TAS
GO:0071556
Q29963 (UniProtKB)
TAS
GO:0000139
Q95604 (UniProtKB)
TAS
GO:0000139
Q95604 (UniProtKB)
TAS
GO:0002474
Q95604 (UniProtKB)
TAS
GO:0002479
Q95604 (UniProtKB)
TAS
GO:0002480
Q95604 (UniProtKB)
TAS
GO:0003823
Q95604 (UniProtKB)
IBA
GO:0005783
Q95604 (UniProtKB)
ISS
GO:0005794
Q95604 (UniProtKB)
ISS
GO:0005886
Q95604 (UniProtKB)
IBA
GO:0005886
Q95604 (UniProtKB)
TAS
GO:0005886
Q95604 (UniProtKB)
TAS
GO:0005886
Q95604 (UniProtKB)
TAS
GO:0005886
Q95604 (UniProtKB)
TAS
GO:0009986
Q95604 (UniProtKB)
ISS
GO:0012507
Q95604 (UniProtKB)
TAS
GO:0012507
Q95604 (UniProtKB)
TAS
GO:0012507
Q95604 (UniProtKB)
TAS
GO:0016032
Q95604 (UniProtKB)
IEA
GO:0019882
Q95604 (UniProtKB)
IBA
GO:0030670
Q95604 (UniProtKB)
TAS
GO:0031901
Q95604 (UniProtKB)
TAS
GO:0031901
Q95604 (UniProtKB)
TAS
GO:0031901
Q95604 (UniProtKB)
TAS
GO:0042605
Q95604 (UniProtKB)
ISS
GO:0042612
Q95604 (UniProtKB)
ISS
GO:0050776
Q95604 (UniProtKB)
TAS
GO:0060333
Q95604 (UniProtKB)
TAS
GO:0060337
Q95604 (UniProtKB)
TAS
GO:0071556
Q95604 (UniProtKB)
TAS
GO:0071556
Q95604 (UniProtKB)
TAS
GO:0071556
Q95604 (UniProtKB)
TAS
GO:0071556
Q95604 (UniProtKB)
TAS
GO:0071556
Q95604 (UniProtKB)
TAS
GO:0071556
Q95604 (UniProtKB)
TAS
GO:0071556
Q95604 (UniProtKB)
TAS
GO:0071556
Q95604 (UniProtKB)
TAS
GO:0071556
Q95604 (UniProtKB)
TAS
GO:0071556
Q95604 (UniProtKB)
TAS
GO:0000139
Q9TNN7 (UniProtKB)
TAS
GO:0000139
Q9TNN7 (UniProtKB)
TAS
GO:0002474
Q9TNN7 (UniProtKB)
TAS
GO:0002479
Q9TNN7 (UniProtKB)
TAS
GO:0002480
Q9TNN7 (UniProtKB)
TAS
GO:0005783
Q9TNN7 (UniProtKB)
ISS
GO:0005794
Q9TNN7 (UniProtKB)
ISS
GO:0005886
Q9TNN7 (UniProtKB)
TAS
GO:0005886
Q9TNN7 (UniProtKB)
TAS
GO:0005886
Q9TNN7 (UniProtKB)
TAS
GO:0005886
Q9TNN7 (UniProtKB)
TAS
GO:0009986
Q9TNN7 (UniProtKB)
ISS
GO:0012507
Q9TNN7 (UniProtKB)
TAS
GO:0012507
Q9TNN7 (UniProtKB)
TAS
GO:0012507
Q9TNN7 (UniProtKB)
TAS
GO:0016020
Q9TNN7 (UniProtKB)
IDA
GO:0016032
Q9TNN7 (UniProtKB)
IEA
GO:0030670
Q9TNN7 (UniProtKB)
TAS
GO:0031901
Q9TNN7 (UniProtKB)
TAS
GO:0031901
Q9TNN7 (UniProtKB)
TAS
GO:0031901
Q9TNN7 (UniProtKB)
TAS
GO:0042605
Q9TNN7 (UniProtKB)
ISS
GO:0042612
Q9TNN7 (UniProtKB)
ISS
GO:0050776
Q9TNN7 (UniProtKB)
TAS
GO:0060333
Q9TNN7 (UniProtKB)
TAS
GO:0060337
Q9TNN7 (UniProtKB)
TAS
GO:0071556
Q9TNN7 (UniProtKB)
TAS
GO:0071556
Q9TNN7 (UniProtKB)
TAS
GO:0071556
Q9TNN7 (UniProtKB)
TAS
GO:0071556
Q9TNN7 (UniProtKB)
TAS
GO:0071556
Q9TNN7 (UniProtKB)
TAS
GO:0071556
Q9TNN7 (UniProtKB)
TAS
GO:0071556
Q9TNN7 (UniProtKB)
TAS
GO:0071556
Q9TNN7 (UniProtKB)
TAS
GO:0071556
Q9TNN7 (UniProtKB)
TAS
GO:0071556
Q9TNN7 (UniProtKB)
TAS

基因相关microRNA

基因相关microRNA

可能调控 HLA-C基因的相关microRNA：     

基因相互作用关系

基因相互作用关系

Reactome

MINT

BioGrid

IntAct

mentha

String

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因通路

基因通路

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Arthritis, Psoriatic 0.289478499 35 2 BeFree_CTD_human_GAD_GWASCAT_LHGDN
Psoriasis 0.252749107 152 3 BeFree_CTD_human_GAD_LHGDN
HIV Infections 0.196134679 60 3 BeFree_CTD_human_GAD_LHGDN
Stevens-Johnson Syndrome 0.12973957 6 0 BeFree_CTD_human_GAD
Hepatitis B, Chronic 0.127372538 4 0 BeFree_CTD_human_GAD
Glioma 0.122367032 2 0 CTD_human_GAD
PSORIASIS SUSCEPTIBILITY 1 0.120814326 3 0 BeFree_CLINVAR
Chronic Obstructive Airway Disease 0.12 1 1 GWASCAT
Adverse reaction to drug 0.12 1 0 CTD_human
LEUKEMIA, ACUTE LYMPHOBLASTIC, SUSCEPTIBILITY TO, 3 0.12 0 0 ORPHANET

基因相关服务

基因相关服务

联系方式

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