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This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
[中文简述(自动翻译):]  此基因编码在细胞生长和迁移的作用,并在胞质分裂的肌动蛋白结合蛋白。该编码的蛋白被认为是调节肌动蛋白足细胞骨架的动态,肾小球的组成部分。在这个基因的突变与局灶节段性肾小球硬化相关8.在多个转录剪接变异体导致编码不同亚型。 [由RefSeq的,2014年10月提供]
ANLN基因(以及对应的蛋白质)的细胞分布位置:
ANLN基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Polycystic Ovary Syndrome | 0.12 | 1 | 0 | CTD_human |
| FOCAL SEGMENTAL GLOMERULOSCLEROSIS 8 | 0.12 | 1 | 0 | UNIPROT |
| Non-Small Cell Lung Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of lung | 0.000271442 | 1 | 0 | BeFree |
| MRSA - Methicillin resistant Staphylococcus aureus infection | 0.000271442 | 1 | 0 | BeFree |
| Carcinogenesis | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
| Liver carcinoma | 0.000271442 | 1 | 0 | BeFree |
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