RNF7(ring finger protein 7)

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

3q22-q24
基因染色体位置图

The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  由该基因编码的蛋白质是高度保守的环指蛋白。它是SKP1-滞/ CDC53-F盒蛋白泛素连接酶,它们是蛋白降解机械细胞周期进展和信号转导的重要的一部分的基本亚单位。这种蛋白质具有相互作用,并且是,酪蛋白激酶Ⅱ(CSNK2A1 / CKII)的衬底。通过CSNK2A1该蛋白质的磷酸化已被证明促进IkappaBalpha(CHUK / IKK-α/ IKBKA)和p27Kip1蛋白(CDKN1B)的降解。已经报道了编码不同同种型的可变剪接转录物变体。 [由RefSeq的,2008年7月提供]

RNF7基因的碱基序列:[NCBI]
RNF7基因的碱基突变:           显示全部snp
rs868934       rs1065369       rs1829258       rs1879284       rs1879285       rs1879286       rs1980190       rs1980191       rs1980192       rs2681694       rs3052146       rs3184648       rs3773840       rs4538350       rs6769676       rs6785010       rs6785106       rs9789959       rs9789973       rs9789997       rs9790069       rs9790073       rs9790075       rs11452917       rs11542226       rs11918543       rs16851717       rs16851720       rs17195449       rs17850027       rs57365200       rs59998648       rs72998395       rs72998398       rs73226658       rs73870348       rs73870349      
rs74776152       rs75171144       rs75854649       rs76037255       rs76285412       rs76642309       rs77870385       rs77971862       rs78477651       rs79073808       rs80061564       rs80238227       rs111262302       rs111369760       rs111558867       rs111796549       rs111814392       rs112162512       rs112619890       rs113738510       rs114584193       rs115219219       rs115267388       rs116335480       rs116389135       rs116444897       rs117481781       rs137871830       rs138166487       rs138261482       rs138840258       rs139318917       rs141023810       rs141114694       rs141479027       rs142106107       rs142492597       rs142752523       rs143654555       rs143709172       rs144117456       rs144956015       rs144978686       rs144995760       rs145535549       rs145573224       rs146686532       rs147146084       rs147300316       rs147465859       rs147894829       rs148124961       rs148628802       rs148937090       rs150074989       rs150133331       rs150206582       rs150735029       rs150861084       rs151176372       rs180793426       rs181007565       rs181168353       rs182175392       rs182282125       rs182577763       rs183061681       rs185119744       rs185139328       rs185260448       rs185809529       rs185873574       rs186027871       rs186428075       rs187047041       rs187757547       rs188425172       rs188537118       rs188712021       rs189464539       rs190114909       rs190196951       rs190400060       rs190735882       rs191390378       rs191497751       rs192013967       rs192030940       rs192875746       rs199875302       rs200542817       rs200808094       rs201440306       rs367690493       rs367943384       rs367979798       rs368501662       rs368685884       rs369758000       rs370015900       rs370181958       rs372166990       rs372950699       rs373601273       rs373752110       rs374071832       rs374197358       rs374365952       rs374610241       rs375149297       rs376638368       rs376688354       rs376997571       rs377033739       rs377041894       rs527696700       rs527793879       rs528292741       rs528331650       rs528464024       rs528733134       rs528770446       rs528797434       rs528953784       rs528993332       rs529970492       rs530144081       rs530177594       rs530655660       rs530727187       rs530776856       rs531186453       rs531187038       rs531242209       rs531410166       rs532104543       rs532308808       rs532349432       rs533097933       rs533541110       rs533606353       rs533630607       rs533642473       rs534114848       rs534355814       rs534553225       rs534589076       rs534686716       rs535056482       rs535143193       rs535301444       rs535667645       rs535902195       rs535986109       rs536081018       rs536240769       rs536279458       rs536830092       rs537552744       rs538041692       rs538619078       rs538630668       rs538939177       rs539024118       rs540540338       rs540750435       rs540810624       rs541053210       rs541622260       rs541946376       rs542065681       rs542168365       rs542182018       rs542818472       rs542900287       rs542965849       rs543166975       rs543254930       rs543453329       rs544379712       rs544522697       rs544552248       rs545578054       rs545621419       rs545709032       rs546335688       rs546858522       rs546897236       rs547076004       rs547281903       rs547418367       rs547858830       rs548815835       rs548855326       rs549135338       rs549686797       rs550518254       rs550583369       rs551038096       rs551972617       rs552973080       rs553009894       rs553517710       rs553556356       rs554102733       rs554325007       rs554626185       rs554865977       rs555372240       rs555573074       rs555601736       rs556438248       rs556492009       rs556969421       rs557005984       rs557016468       rs557628573       rs557769532       rs558153944       rs558192659       rs558211706       rs558696999       rs558818838       rs559163938       rs559318905       rs560290902       rs560428461       rs560626983       rs561685599       rs561726300       rs562543555       rs562766559       rs562881615       rs562989431       rs563349677       rs563412075       rs563955338       rs563991735       rs564075863       rs564398732       rs564568100       rs564604084       rs565138662       rs565233823       rs565270444       rs566274433       rs566297141       rs566334329       rs566364240       rs566519261       rs566882974       rs567472520       rs567608447       rs567669262       rs567847131       rs567995145       rs568175930       rs568666358       rs568773802       rs568889469       rs568998531       rs569085096       rs569121854       rs569210181       rs569277536       rs570173930       rs570264050       rs570405511       rs571249958       rs571365525       rs571454708       rs571489569       rs571527092       rs571615449       rs571870052       rs571896152       rs571984034       rs572582115       rs573085085       rs573171653       rs573821866       rs573896364       rs574085544       rs574121349       rs574528916       rs574722384       rs575031361       rs575286284       rs575841928       rs575902803       rs576254646       rs576320677       rs576518470       rs576557456       rs576613237       rs576649656       rs577157028       rs577418247       rs577512116       rs577701084       rs577824881       rs745647306       rs745709011       rs745868504       rs746306815       rs746879906       rs746984630       rs747872964       rs748219433       rs748989232       rs750036239       rs750077601       rs750966922       rs751338696       rs752036084       rs753190133       rs753387632       rs753995730       rs754233242       rs754972338       rs755895715       rs757039175       rs757635464       rs757831209       rs758041616       rs758153573       rs758795421       rs758998616       rs759352977       rs759735636       rs760090384       rs761016216       rs761245412       rs761265547       rs761451631       rs761980057       rs762067939       rs763746670       rs763966333       rs764106232       rs764298806       rs764758505       rs765361213       rs765540812       rs765626570       rs766789858       rs767448760       rs767668935       rs767675459       rs768135272       rs768231803       rs768554312       rs768758643       rs769546485       rs769784729       rs769843707       rs770363603       rs770882226       rs771172180       rs771254020       rs771836531       rs771891264       rs773689545       rs773986992       rs774442577       rs774698120       rs774835062       rs775667525       rs775709198       rs776503650       rs776656900       rs776863831       rs777869709       rs778827653       rs779401417       rs779758436       rs779862243       rs780524737       rs780801315       rs781304348       rs867569147      

RNF7基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图

RNF7基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

RNF7基因的本位(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0004842
F8WEU8(UniProtKB)
IEA
GO:0005680
F8WEU8(UniProtKB)
IEA
GO:0016567
F8WEU8(UniProtKB)
IEA
GO:0005507
Q9UBF6(UniProtKB)
TAS
GO:0005515
Q9UBF6(UniProtKB)
IPI
GO:0005515
Q9UBF6(UniProtKB)
IPI
GO:0005515
Q9UBF6(UniProtKB)
IPI
GO:0005515
Q9UBF6(UniProtKB)
IPI
GO:0005515
Q9UBF6(UniProtKB)
IPI
GO:0005515
Q9UBF6(UniProtKB)
IPI
GO:0005634
Q9UBF6(UniProtKB)
NAS
GO:0005654
Q9UBF6(UniProtKB)
IDA
GO:0005737
Q9UBF6(UniProtKB)
IDA
GO:0005737
Q9UBF6(UniProtKB)
NAS
GO:0008270
Q9UBF6(UniProtKB)
IEA
GO:0019788
Q9UBF6(UniProtKB)
IDA
GO:0031146
Q9UBF6(UniProtKB)
IBA
GO:0031462
Q9UBF6(UniProtKB)
IBA
GO:0031463
Q9UBF6(UniProtKB)
IBA
GO:0031466
Q9UBF6(UniProtKB)
IDA
GO:0031467
Q9UBF6(UniProtKB)
IBA
GO:0042787
Q9UBF6(UniProtKB)
IBA
GO:0043224
Q9UBF6(UniProtKB)
IBA
GO:0045116
Q9UBF6(UniProtKB)
IDA
GO:0051775
Q9UBF6(UniProtKB)
TAS
GO:0061630
Q9UBF6(UniProtKB)
IBA
GO:0080008
Q9UBF6(UniProtKB)
IBA
GO:0097602
Q9UBF6(UniProtKB)
IDA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控RNF7基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Biliary Cirrhosis, Secondary 0.12 1 1 GWASCAT
Oguchi disease 0.000814326 3 0 BeFree
Toxic Shock Syndrome 0.000542884 2 0 BeFree
Staphylococcal toxic shock syndrome 0.000542884 2 0 BeFree
Cardiovascular Diseases 0.000271442 1 0 BeFree
Diabetes Mellitus, Insulin-Dependent 0.000271442 1 0 BeFree
Ischemia 0.000271442 1 0 BeFree
Mucocutaneous Lymph Node Syndrome 0.000271442 1 0 BeFree
Pharyngitis 0.000271442 1 0 BeFree
Diabetic Foot 0.000271442 1 0 BeFree
Prosthetic joint infection 0.000271442 1 0 BeFree
Colon Carcinoma 0.000271442 1 0 BeFree
Diabetic foot ulcer 0.000271442 1 0 BeFree
Skin Carcinogenesis 0.000271442 1 0 BeFree
没有相关文献
我要说两句
热门评论
还没有评论,赶快来抢沙发吧。

登陆

用户名:

密    码:

联系方式

山东省济南市 高新区 崇华路359号 三庆世纪财富中心C1115室

电话: 0531-88819269

E-mail: product@genelibs.com

微信公众号

扫一扫右方二维码,关注微信订阅号,实时查看信息,关注医学生物学动态。