RNF5(ring finger protein 5, E3 ubiquitin protein ligase)

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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6p21.31
基因染色体位置图

The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  由该基因编码的蛋白质中含有RING指,这是公知的是参与蛋白质 - 蛋白质相互作用的基序。这种蛋白质是一种膜结合泛素连接酶。它可以通过瞄准桩蛋白泛素化和改变桩蛋白在细胞浆和粘着斑的分布和本地化调节细胞运动。 [由RefSeq的,2008年7月提供]

RNF5基因的碱基序列:[NCBI]
RNF5基因的碱基突变:           显示全部snp
rs8365       rs41270464       rs56087420       rs140366801       rs144228131       rs146434120       rs147340908       rs181176444       rs181811810       rs188348154       rs191750543       rs200524532       rs201575255       rs368755329       rs370335494       rs370891239       rs373746820       rs374700378       rs376556772       rs376629755       rs529694471       rs534481227       rs541160445       rs547847182       rs552049816       rs560762988       rs564032715       rs564695318       rs567917711       rs569295409       rs745528625       rs745561854       rs748638860       rs749159581       rs752089701       rs753000568       rs753154473      
rs757855810       rs758873207       rs759655645       rs762956950       rs764515549       rs765537169       rs768698847       rs770950798       rs773418394       rs775449476       rs776159506       rs777243806       rs779413134       rs779678781       rs780541384       rs2071290       rs2269423       rs3096689       rs3130349       rs3132965       rs3134943       rs3134944       rs3134945       rs3134946       rs3134947       rs9380283       rs9469089       rs11970384       rs16868402       rs17493811       rs35746374       rs36022314       rs41268928       rs57301060       rs57409105       rs59564381       rs74395371       rs112036792       rs112124640       rs114959175       rs138854481       rs139977264       rs143091746       rs143287032       rs144014361       rs146416475       rs147473782       rs148565510       rs148878374       rs151021379       rs180719518       rs182637027       rs183637818       rs185565399       rs186987838       rs187465580       rs190444026       rs190925320       rs191766949       rs192954285       rs200253127       rs200753487       rs201615677       rs201670163       rs368492645       rs370126800       rs372344349       rs372383772       rs373300034       rs374652403       rs374805052       rs374932399       rs375340400       rs375375966       rs375416151       rs376401028       rs377192058       rs527481006       rs528000552       rs528290088       rs530254587       rs530461784       rs531610618       rs531796614       rs532698141       rs533675645       rs536841413       rs538599868       rs538659155       rs539113875       rs542472306       rs542553625       rs542758753       rs543495442       rs543554669       rs545310641       rs545368482       rs547380649       rs549251532       rs554099349       rs554113438       rs555434653       rs556232978       rs556290117       rs559725081       rs561393910       rs564964384       rs564986162       rs565713605       rs565977501       rs567328186       rs570137390       rs571622453       rs574738502       rs577690908       rs745365186       rs745844149       rs746508798       rs746859723       rs747287288       rs747520493       rs747944470       rs748217430       rs748270622       rs748514183       rs748921200       rs749050679       rs749268597       rs750217083       rs750929529       rs751228761       rs751298699       rs751968956       rs752402980       rs752875872       rs753103073       rs753286828       rs753393917       rs754068950       rs754548745       rs754560846       rs754596503       rs754999125       rs755231131       rs755357885       rs755588650       rs755607931       rs756010995       rs756707639       rs757729044       rs758091503       rs758228681       rs758522209       rs758723209       rs758750126       rs759173530       rs759208615       rs759603933       rs760143932       rs760219823       rs760524852       rs761173205       rs762043377       rs762486403       rs762608675       rs762720554       rs762923211       rs763061242       rs763159722       rs763466615       rs763596055       rs764337609       rs764387970       rs764873407       rs765238416       rs765421261       rs765896308       rs766090969       rs766250969       rs766600883       rs766785904       rs766951877       rs767613747       rs767897690       rs767950738       rs768101414       rs768240038       rs768336632       rs768452413       rs768723851       rs769379002       rs769482583       rs770767056       rs770949300       rs771235444       rs771331731       rs772602283       rs772870083       rs773420897       rs773642829       rs773823528       rs774268695       rs774393683       rs774512559       rs775059533       rs775247192       rs775322952       rs775399252       rs775742093       rs776153880       rs776224981       rs777032859       rs777733601       rs777791713       rs778211806       rs778285711       rs778778854       rs779359902       rs779455602       rs779688355       rs780921402       rs781247655       rs781712644       rs1062070       rs140870201       rs141519084       rs147175955       rs373646558       rs375190667       rs569803151       rs746175907       rs746686536       rs749831175       rs750575471       rs750705971       rs751640800       rs751644122       rs753727104       rs753783229       rs754215069       rs756370811       rs756493801       rs757295621       rs757472556       rs758165894       rs758370065       rs759318307       rs759497584       rs760400177       rs761294384       rs761911506       rs765161450       rs765206805       rs766193818       rs766772205       rs767727899       rs769088778       rs769198887       rs770619348       rs771578017       rs772815535       rs772868624       rs773877482       rs775292807       rs776380702       rs777410200       rs779348846       rs780540769       rs781620881       rs200758775       rs755314237      

RNF5基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图

RNF5基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

RNF5基因的本位(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0008270
A0A140TA09(UniProtKB)
IEA
GO:0004842
Q99942(UniProtKB)
IDA
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0005515
Q99942(UniProtKB)
IPI
GO:0008270
Q99942(UniProtKB)
IEA
GO:0009617
Q99942(UniProtKB)
IEA
GO:0010507
Q99942(UniProtKB)
IEA
GO:0016021
Q99942(UniProtKB)
IEA
GO:0016874
Q99942(UniProtKB)
IEA
GO:0031648
Q99942(UniProtKB)
IEA
GO:0031966
Q99942(UniProtKB)
IEA
GO:0036503
Q99942(UniProtKB)
IGI
GO:0036503
Q99942(UniProtKB)
IMP
GO:0044257
Q99942(UniProtKB)
IMP
GO:0070534
Q99942(UniProtKB)
IDA
GO:0070936
Q99942(UniProtKB)
IDA
GO:0071712
Q99942(UniProtKB)
IMP
GO:1904264
Q99942(UniProtKB)
TAS
GO:2000785
Q99942(UniProtKB)
IEA
GO:0036513
Q99942(UniProtKB)
IDA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控RNF5基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Idiopathic Membranous Glomerulonephritis 0.12 1 1 GWASCAT
Diabetes Mellitus, Insulin-Dependent 0.004734064 1 1 GAD
Mammary Neoplasms 0.00272435 1 0 LHGDN
Lupus Erythematosus, Systemic 0.002367032 1 0 GAD
Malignant neoplasm of breast 0.000542884 2 0 BeFree
Virus Diseases 0.000542884 2 0 BeFree
Breast Carcinoma 0.000542884 2 0 BeFree
Kidney Neoplasm 0.000271442 1 0 BeFree
melanoma 0.000271442 1 0 BeFree
Pulmonary Emphysema 0.000271442 1 0 BeFree
Tumor Progression 0.000271442 1 0 BeFree
Metastatic melanoma 0.000271442 1 0 BeFree
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