RNF4(ring finger protein 4)

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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4p16.3
基因染色体位置图

The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.[provided by RefSeq, Jul 2010]

[中文简述(自动翻译):]  由该基因编码的蛋白质中含有RING指基序,并充当转录调节。此蛋白已被证明与相互作用,并抑制,TRPS1,GATA-介导的转录的转录抑制活性。转录阻抑ZNF278 / PATZ被发现与该蛋白相互作用,并因此减少通过该蛋白介导的雄激素受体依赖性转录的增强。在小鼠和大鼠的对应的研究表明在精子发生这种蛋白的作用。这种基因的一个假的1号染色体上[由RefSeq的,2010年7月提供]研究发现

RNF4基因的碱基序列:[NCBI]
RNF4基因的碱基突变:           显示全部snp
rs704347       rs704348       rs704349       rs704350       rs704351       rs704352       rs704353       rs704354       rs704355       rs846178       rs846236       rs846237       rs846238       rs846239       rs846240       rs846241       rs846242       rs846243       rs846244       rs846245       rs961067       rs1048678       rs1048679       rs1048727       rs1070968       rs1070969       rs1099774       rs1099775       rs1099776       rs1099777       rs1099778       rs1099779       rs1099785       rs1099786       rs1203847       rs1203848       rs1203849      
rs1203851       rs1203852       rs1203853       rs1203854       rs1203855       rs1203856       rs1203857       rs1203858       rs1203859       rs1203860       rs1203861       rs1203862       rs1203863       rs1203864       rs1619657       rs1630081       rs1728269       rs1770823       rs2157106       rs2187699       rs2269488       rs2269490       rs2282765       rs2354502       rs2354513       rs3108490       rs3108491       rs3108492       rs3108493       rs3108496       rs3121160       rs3121161       rs3121162       rs3128765       rs3128766       rs3128834       rs3128839       rs3135151       rs3216205       rs3749467       rs3762830       rs3762831       rs3762832       rs3792601       rs3849663       rs3849666       rs3860712       rs3860713       rs3911905       rs3911906       rs4974694       rs4974695       rs4974696       rs4974697       rs4974700       rs4974702       rs4974704       rs4974707       rs4974708       rs4974709       rs5855735       rs6838884       rs7666439       rs7676728       rs7684966       rs7688476       rs10004477       rs10007662       rs11248108       rs11542962       rs11734497       rs11935873       rs13102855       rs13111707       rs13121196       rs13128459       rs13135697       rs17132599       rs17132608       rs17132645       rs17132647       rs17132652       rs17772769       rs17823737       rs28503940       rs28613352       rs28708609       rs34376263       rs34392249       rs34514346       rs34594225       rs34742072       rs34930071       rs35085989       rs35315554       rs35454362       rs35616649       rs35674085       rs35678836       rs35752001       rs35769217       rs35847184       rs35950215       rs55745322       rs55958805       rs59073339       rs60851498       rs61616696       rs61738929       rs61790176       rs61790178       rs61790179       rs61790181       rs61790182       rs61790183       rs66500906       rs66571775       rs67427439       rs67508332       rs71167793       rs71606399       rs71606400       rs71606401       rs71606402       rs71608203       rs71608204       rs71608205       rs73076402       rs73078314       rs73078319       rs73205500       rs73205502       rs73791836       rs74515305       rs74722774       rs74744855       rs74758122       rs74765207       rs74939123       rs75109465       rs75131312       rs75303719       rs75316910       rs75320995       rs75401733       rs75762849       rs75926421       rs75941518       rs76090282       rs76268614       rs76401602       rs76532290       rs76671438       rs76677093       rs76719057       rs76821628       rs76831318       rs76857840       rs77450750       rs77512325       rs77578279       rs77644669       rs77650973       rs77775219       rs77778937       rs77881709       rs78088702       rs78285382       rs78287554       rs78431969       rs78439795       rs78443729       rs78457814       rs78472434       rs78627969       rs78680204       rs78913727       rs78989649       rs79205547       rs79268809       rs79540986       rs79813605       rs79899335       rs79941067       rs80039100       rs80180918       rs80199880       rs80260252       rs80272890       rs111241623       rs111271670       rs111277729       rs111356905       rs111528897       rs111553325       rs111556263       rs111563236       rs111591172       rs111772927       rs111791215       rs111814089       rs111929518       rs111983570       rs112027285       rs112189106       rs112243545       rs112255088       rs112268567       rs112334910       rs112447155       rs112485564       rs112573696       rs112602729       rs112662060       rs112666745       rs112670279       rs112680139       rs112732689       rs112734303       rs112769602       rs112831279       rs112934235       rs112957310       rs112985336       rs113015139       rs113028044       rs113043315       rs113054000       rs113093233       rs113111408       rs113119624       rs113162148       rs113174872       rs113326806       rs113343869       rs113417443       rs113424841       rs113642465       rs113663143       rs113663902       rs113675632       rs113717693       rs113731782       rs113878655       rs113985933       rs113988971       rs114029459       rs114087743       rs114127428       rs114368415       rs114447185       rs114568474       rs114572047       rs114655185       rs114790211       rs114888148       rs114926392       rs115022631       rs115024439       rs115045410       rs115079532       rs115141138       rs115156037       rs115267788       rs115321251       rs115433476       rs115459486       rs115509407       rs115573056       rs115589473       rs115661611       rs115670961       rs115715882       rs115725163       rs115867270       rs115904385       rs115916043       rs115981510       rs116103255       rs116336654       rs116385861       rs116451748       rs116645369       rs116727848       rs116732707       rs116739336       rs116790538       rs116801286       rs116950939       rs116953145       rs117110754       rs117206896       rs117481016       rs117487486       rs117653625       rs118106582       rs118120598       rs118155233       rs137919359       rs138006183       rs138110007       rs138201097       rs138372552       rs138425046       rs138432590       rs138598435       rs138626654       rs138670672       rs138682232       rs138856956       rs138915893       rs138969822       rs138976361       rs139002127       rs139051125       rs139051650       rs139053065       rs139117774       rs139156683       rs139192214       rs139227468       rs139399307       rs139437305       rs139513670       rs139544165       rs139611007       rs139618494       rs139689946       rs139752160       rs139796899       rs139834379       rs140033961       rs140110053       rs140177488       rs140184705       rs140320973       rs140359334       rs140400868       rs140424790       rs140553862       rs140592185       rs140679704       rs140712612       rs141021221       rs141058569       rs141640314       rs141642997       rs141650780       rs141706372       rs141753527       rs141890765       rs141927080       rs141931639       rs142054476       rs142121671       rs142127137       rs142428150       rs142489895       rs142503535       rs142569699       rs142680670       rs142718087       rs142768082       rs142829484       rs142860373       rs142924316       rs143022075       rs143034786       rs143056788       rs143143913       rs143300910       rs143446599       rs143635667       rs143675922       rs143755816       rs143885587       rs143968265       rs143979680       rs144037471       rs144084399       rs144100472       rs144235534       rs144321790       rs144369516       rs144386107       rs144408721       rs144544864       rs144626285       rs144678026       rs144783504       rs144795414       rs144834946       rs144896551       rs144899447       rs144932801       rs145104971       rs145139240       rs145149983       rs145220445       rs145267098       rs145301910       rs145441106       rs145461079       rs145497140       rs145534473       rs145743629       rs145823583       rs145905792       rs145997077       rs146060620       rs146080717       rs146099404       rs146100453       rs146321169       rs146339835       rs146396213       rs146415553       rs146628973       rs146646935       rs146655450       rs146665115       rs146749291       rs146768207       rs146785301       rs146888973       rs146929026       rs146977648       rs147033343       rs147049394       rs147193111       rs147226029       rs147244454       rs147422221       rs147438868       rs147526792       rs147544156       rs147597590       rs147599139       rs147615745       rs147686803       rs147702937       rs147714212       rs147825500       rs147913755       rs147930463       rs148003108       rs148055258       rs148112615       rs148124553       rs148177198       rs148196971       rs148388874       rs148442319       rs148494198       rs148496542       rs148512601       rs148529651       rs148564351       rs148774761       rs148794369       rs148831029       rs148882164       rs149040603       rs149111435       rs149130025       rs149162942       rs149232127       rs149361944       rs149484206       rs149503344       rs149571779       rs149680384       rs149747332       rs149872348       rs149890125       rs150119266       rs150208561       rs150240836       rs150276914       rs150419098       rs150468885       rs150489185       rs150508145       rs150598564       rs150666413       rs150786510       rs150805793       rs151108778       rs151161337       rs151177981       rs151249254       rs180678384       rs180689545       rs180758875       rs180765810       rs180772253       rs180778520       rs181106905       rs181128017       rs181219795       rs181224097       rs181230842       rs181317813       rs181328423       rs181348747       rs181366815       rs181379519       rs181393733       rs181478149       rs181533370       rs181583458       rs181705380       rs181859833       rs181867271       rs182021922       rs182044903       rs182045698       rs182062720       rs182062977       rs182087596       rs182103120       rs182325270       rs182327958       rs182458066       rs182589002       rs182706270       rs182719200       rs182895513       rs182900600       rs182935795       rs182997677       rs183046346       rs183238224       rs183263385       rs183264098       rs183291491       rs183296597       rs183306741       rs183428685       rs183536929       rs183550165       rs183581536       rs183783499       rs183867406       rs183899061       rs183903277       rs183916598       rs183919063       rs184026204       rs184062732       rs184064163       rs184079758       rs184096392       rs184116029       rs184141948       rs184150796       rs184175730       rs184297708       rs184436691       rs184445194       rs184453421       rs184458138       rs184491085       rs184587538       rs184624141       rs184658866       rs184674577       rs184695481       rs184728672       rs184738071       rs184779584       rs184844259       rs184868106       rs184904559       rs184974200       rs185254910       rs185261132       rs185298555       rs185302417       rs185315025       rs185315739       rs185426401       rs185560684       rs185647646       rs185698108       rs185784678       rs186042743       rs186054319       rs186154610       rs186197646       rs186200011       rs186292830       rs186301265       rs186309931       rs186321415       rs186409630       rs186486948       rs186490781       rs186505844       rs186603706       rs186611044       rs186613178       rs186613842       rs186817993       rs186828667       rs186945765       rs186968160       rs187067384       rs187073363       rs187150160       rs187169061       rs187224089       rs187251303       rs187270401       rs187451797       rs187456400       rs187466930       rs187468538       rs187498447       rs187537112       rs187541545       rs187632241       rs187641230       rs187644097       rs187656224       rs187668223       rs187682757       rs187749578       rs187781807       rs187796606       rs188030738       rs188068278       rs188193089       rs188282950       rs188314692       rs188323636       rs188329139       rs188530685       rs188562031       rs188576287       rs188601998       rs188666189       rs188696703       rs188861503       rs188915134       rs188929463       rs188984626       rs189091665       rs189323296       rs189329072       rs189342786       rs189438628       rs189444638       rs189472098       rs189607898       rs189668480       rs189678584       rs189703369       rs189714832       rs189790237       rs189806797       rs189844494       rs189903619       rs190003388       rs190145560       rs190235703       rs190241979       rs190242767       rs190252326       rs190256769       rs190271595       rs190276522       rs190479993       rs190511231       rs190595342       rs190606815       rs190644205       rs190658294       rs190753872       rs190786778       rs190798734       rs191008536       rs191047869       rs191128328       rs191174085       rs191250621       rs191299202       rs191481612       rs191489526       rs191550319       rs191554177       rs191564067       rs191731714       rs191804767       rs191866291       rs191943195       rs192152185       rs192166209       rs192171257       rs192388194       rs192398572       rs192438564       rs192534307       rs192566553       rs192615016       rs192616987       rs192758128       rs192792381       rs192811550       rs192828384       rs193005150       rs193025550       rs193179010       rs193302621       rs199558155       rs199594310       rs199597855       rs201124565       rs201229382       rs201268592       rs201448316       rs201590250       rs202155627       rs202183324       rs367574121       rs367662183       rs367691881       rs367884807       rs368063195       rs368421109       rs368538178       rs368570728       rs368633886       rs368710913       rs368864481       rs368866293       rs368920708       rs368992225       rs368998654       rs369045099       rs369081383       rs369245327       rs369402347       rs369677397       rs369919967       rs369955486       rs369967508       rs370109776       rs370247859       rs370296465       rs370384434       rs370477539       rs370757861       rs370948907       rs371267361       rs371680420       rs371694147       rs371708162       rs371845506       rs371898301       rs372073457       rs372281762       rs372410652       rs372656978       rs372726393       rs372738436       rs372844181       rs372857510       rs373155970       rs373647437       rs373770063       rs373800748       rs373883962       rs373921435       rs373940145       rs374288873       rs374459693       rs374586915       rs374610233       rs374740340       rs375116646       rs375252376       rs375321626       rs375494181       rs375976580       rs376505096       rs376614192       rs376792391       rs376985025       rs377036277       rs377235636       rs377313523       rs377370930       rs377441425       rs377454354       rs377491979       rs377507743       rs377600326       rs377629542       rs377754372       rs397697374       rs527266372       rs527318263       rs527333634       rs527392166       rs527440373       rs527503651       rs527663770       rs527670073       rs527733546       rs527738128       rs527799921       rs527851287       rs528035102       rs528051494       rs528077313       rs528078606       rs528139997       rs528141828       rs528204663       rs528261657       rs528407649       rs528428593       rs528707279       rs528708840       rs528731616       rs528738133       rs528739622       rs528857303       rs528941030       rs528941364       rs528983070       rs529055634       rs529101728       rs529120470       rs529151980       rs529209690       rs529271647       rs529288363       rs529333272       rs529343474       rs529350355       rs529365121       rs529568108       rs529596680       rs529606411       rs529796537       rs529881426       rs529902901       rs529919717       rs529929577       rs529957823       rs530006143       rs530013784       rs530019479       rs530140463       rs530143481       rs530146074       rs530254284       rs530363578       rs530421335       rs530499328       rs530502943       rs530558147       rs530568685       rs530606260       rs530648292       rs530680661       rs530697647       rs530716763       rs530762084       rs530768641       rs530796771       rs530837396       rs530905416       rs530984839       rs530994284       rs531057838       rs531127265       rs531162720       rs531211015       rs531272269       rs531289451       rs531290807       rs531385817       rs531484788       rs531494012       rs531560553       rs531697658       rs531703283       rs531710570       rs531765695       rs531770581       rs531826696       rs531827672       rs531932672       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rs575822828       rs575890754       rs575893425       rs575901312       rs575949196       rs576004542       rs576009114       rs576048993       rs576121905       rs576139113       rs576180492       rs576242092       rs576261417       rs576344489       rs576420695       rs576473769       rs576493089       rs576709120       rs576762911       rs576807792       rs576891906       rs576930915       rs576946683       rs577013962       rs577191171       rs577283640       rs577345683       rs577374174       rs577415630       rs577433663       rs577495084       rs577504246       rs577596488       rs577640048       rs577676753       rs577718819       rs577757883       rs577780382       rs577788462       rs577814981       rs577816563       rs577844226       rs577859448       rs577900515       rs577945911       rs577956874       rs577996205       rs578019614       rs578065896       rs578107893       rs578154009       rs578250375       rs745369954       rs745650349       rs745756669       rs746134259       rs746864045       rs746907774       rs747526963       rs747852420       rs748164674       rs748270834       rs748304698       rs748321730       rs748574123       rs748627129       rs748844885       rs749110248       rs749158474       rs749313483       rs749398246       rs749452553       rs749661392       rs750044459       rs750049464       rs750599857       rs750844745       rs750889099       rs750897446       rs751185060       rs751237758       rs751523263       rs751794780       rs751991252       rs752043006       rs752372271       rs752503673       rs752628893       rs752816338       rs752921900       rs753084424       rs753124356       rs753448501       rs753502582       rs753698455       rs753957643       rs753962865       rs754311489       rs754355085       rs754510364       rs754818387       rs755056389       rs755252409       rs755307762       rs755309491       rs755358618       rs755654011       rs755878035       rs756128666       rs756252723       rs756304008       rs756960636       rs757013685       rs757262508       rs757384952       rs757450964       rs757564554       rs757836910       rs758063460       rs758523552       rs758666344       rs758717754       rs758846809       rs759399441       rs759553746       rs759659404       rs759777847       rs759970915       rs760070877       rs760253504       rs760543519       rs760739395       rs761016531       rs761227258       rs761537763       rs762033984       rs762231618       rs762438738       rs762609689       rs762655240       rs763148428       rs763205600       rs763395527       rs763470409       rs763617015       rs764005697       rs764849350       rs765540384       rs765597802       rs765821901       rs766120500       rs766178455       rs766527093       rs766584163       rs766666433       rs766858626       rs766953731       rs767261720       rs767319047       rs767401884       rs767591412       rs767833124       rs767883394       rs768425793       rs768926508       rs769074192       rs769457459       rs769489531       rs769509842       rs769809942       rs769839681       rs770236351       rs770378073       rs770638160       rs770802885       rs770967471       rs771939315       rs771994341       rs772404727       rs772605177       rs772652179       rs772745682       rs773046481       rs773120739       rs773587391       rs773600299       rs773775159       rs774124119       rs774147788       rs774870358       rs774983658       rs775128450       rs775364915       rs775952233       rs776095680       rs776525878       rs776582971       rs776915187       rs777167492       rs777372357       rs777422183       rs777845108       rs777851085       rs778227987       rs778423190       rs778621168       rs778927684       rs778955787       rs779065198       rs779549191       rs779609574       rs779913222       rs780138222       rs780192804       rs780276391       rs780396624       rs780826733       rs781178259       rs781190878       rs781269666       rs796735825      

RNF4基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图

RNF4基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

RNF4基因的本位(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0008270
D6RA71(UniProtKB)
IEA
GO:0008270
H0YAI5(UniProtKB)
IEA
GO:0003677
P78317(UniProtKB)
ISS
GO:0003700
P78317(UniProtKB)
TAS
GO:0003713
P78317(UniProtKB)
NAS
GO:0004842
P78317(UniProtKB)
ISS
GO:0005515
P78317(UniProtKB)
IPI
GO:0005515
P78317(UniProtKB)
IPI
GO:0005515
P78317(UniProtKB)
IPI
GO:0005634
P78317(UniProtKB)
IDA
GO:0005654
P78317(UniProtKB)
TAS
GO:0005737
P78317(UniProtKB)
IDA
GO:0006351
P78317(UniProtKB)
IEA
GO:0008134
P78317(UniProtKB)
IBA
GO:0008270
P78317(UniProtKB)
IEA
GO:0016567
P78317(UniProtKB)
IBA
GO:0016874
P78317(UniProtKB)
IEA
GO:0030521
P78317(UniProtKB)
NAS
GO:0031491
P78317(UniProtKB)
ISS
GO:0032184
P78317(UniProtKB)
ISS
GO:0032184
P78317(UniProtKB)
IBA
GO:0033234
P78317(UniProtKB)
IBA
GO:0033768
P78317(UniProtKB)
IBA
GO:0042802
P78317(UniProtKB)
IPI
GO:0043161
P78317(UniProtKB)
IMP
GO:0043161
P78317(UniProtKB)
IMP
GO:0043161
P78317(UniProtKB)
IMP
GO:0045893
P78317(UniProtKB)
ISS
GO:0045944
P78317(UniProtKB)
IDA
GO:0046685
P78317(UniProtKB)
IDA
GO:0050681
P78317(UniProtKB)
NAS
GO:0051865
P78317(UniProtKB)
ISS
GO:0061630
P78317(UniProtKB)
IBA
GO:0061630
P78317(UniProtKB)
TAS
GO:0070534
P78317(UniProtKB)
ISS
GO:0070936
P78317(UniProtKB)
ISS
GO:0070979
P78317(UniProtKB)
ISS
GO:0085020
P78317(UniProtKB)
ISS
GO:0090169
P78317(UniProtKB)
IMP
GO:0090234
P78317(UniProtKB)
IMP
GO:0016605
P78317(UniProtKB)
IDA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控RNF4基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Tobacco Use Disorder 0.002367032 1 0 GAD
Blood pressure finding 0.002367032 1 1 GAD
Systemic arterial pressure 0.002367032 1 1 GAD
Prader-Willi Syndrome 0.000542884 2 0 BeFree
Promyelocytic leukemia 0.000542884 2 0 BeFree
Fanconi Anemia 0.000271442 1 0 BeFree
Acute Promyelocytic Leukemia 0.000271442 1 0 BeFree
Leukoencephalopathy, Progressive Multifocal 0.000271442 1 0 BeFree
Carcinoma of Male Breast 0.000271442 1 0 BeFree
Malignant neoplasm of male breast 0.000271442 1 0 BeFree
Reifenstein Syndrome 0.000271442 1 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree
FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) 0.000271442 1 0 BeFree
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