RNASEL(ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent))

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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1q25
基因染色体位置图

This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  该基因编码的干扰素调节2-5A系统,在抗病毒和干扰素的抗增殖作用的功能的一个组件。在这种基因突变与易感性前列腺癌相关联,并且该基因是遗传性前列腺癌1(HPC1)等??位基因的候选者。 [由RefSeq的,2008年7月提供]

RNASEL基因的碱基序列:[NCBI]
RNASEL基因的碱基突变:           显示全部snp
rs11072       rs486907       rs501286       rs516134       rs533259       rs557934       rs579006       rs589402       rs589974       rs611280       rs618685       rs620070       rs627928       rs641265       rs642917       rs672018       rs672527       rs682585       rs1048254       rs1048255       rs1048256       rs1048260       rs2274509       rs2333446       rs3738579       rs4047860       rs6424863       rs6661378       rs6690434       rs7513620       rs7534480       rs10911100       rs10911102       rs11590556       rs11807829       rs12041279       rs12087797      
rs12736689       rs12742422       rs12743617       rs16859244       rs16859248       rs34085847       rs34510815       rs35328657       rs35553278       rs35632578       rs35896902       rs36053738       rs36061971       rs56001132       rs56173312       rs56250729       rs56270773       rs61806475       rs71297859       rs71632155       rs71632156       rs72725073       rs73061324       rs73061336       rs73061339       rs73061345       rs74128978       rs74315364       rs74315365       rs74415354       rs74599944       rs74792665       rs75136036       rs75324484       rs75403961       rs75640912       rs76296166       rs76367015       rs76391909       rs76420990       rs76463717       rs77064932       rs78132469       rs78199386       rs78203070       rs78685194       rs79409647       rs79669188       rs79954773       rs80193284       rs111243644       rs111694612       rs111705002       rs111807215       rs111813921       rs112325086       rs112714021       rs112862116       rs112900933       rs113130908       rs113175661       rs113207201       rs113469614       rs113978588       rs114166108       rs114289564       rs114573832       rs114901091       rs115044380       rs115634589       rs115739044       rs115807686       rs116246315       rs116621119       rs116717840       rs116743604       rs117584632       rs117790439       rs118142156       rs137866858       rs137956140       rs137993708       rs138081201       rs138303340       rs138584961       rs138606663       rs138685180       rs138740835       rs138925013       rs138930837       rs138978618       rs139026705       rs139522937       rs139629148       rs139665895       rs139877811       rs140469986       rs140555012       rs140640096       rs140651703       rs140715742       rs140739535       rs140919174       rs141087868       rs141194514       rs141239442       rs141618463       rs141691276       rs141725945       rs141809307       rs141997272       rs142133260       rs142266885       rs142399625       rs142706121       rs142849626       rs142939718       rs143187669       rs143374873       rs143544690       rs143546054       rs143565946       rs143649586       rs144113003       rs144213776       rs144273746       rs144337765       rs144363880       rs144467001       rs144939368       rs145147185       rs145415894       rs145581875       rs145787003       rs145794964       rs145835371       rs145873160       rs146336238       rs146365994       rs146621360       rs146629478       rs146640810       rs146781980       rs146801894       rs146872959       rs146939309       rs147002678       rs147141911       rs147149649       rs147210976       rs147433564       rs147610466       rs147890567       rs147898031       rs148067080       rs148236432       rs148411578       rs148464936       rs148741721       rs148752337       rs148806659       rs149070515       rs149129827       rs149140894       rs149194780       rs149283506       rs149498082       rs149778758       rs149936055       rs149964724       rs149982407       rs150252736       rs150572727       rs150721457       rs150746690       rs151012620       rs151056294       rs151067267       rs151287823       rs151296858       rs180755960       rs180839384       rs181055950       rs181330853       rs181550425       rs181653691       rs181809139       rs181995487       rs182287096       rs182444668       rs182539049       rs183074063       rs183141948       rs183339194       rs183399204       rs183647666       rs184061573       rs184350005       rs184605348       rs185001223       rs185093230       rs185208631       rs185335389       rs185402037       rs185452535       rs185948854       rs186259920       rs186330637       rs186703609       rs186718514       rs186980443       rs187138856       rs187223005       rs187320101       rs187579413       rs188223507       rs188425297       rs188496502       rs188753337       rs188754390       rs189421075       rs189430801       rs189586330       rs189744833       rs189963095       rs190292485       rs190359946       rs190380812       rs190604203       rs191210183       rs191214655       rs191430138       rs191464754       rs192066212       rs192505461       rs192719507       rs192838305       rs193195484       rs193258729       rs199515181       rs199662278       rs199681551       rs199717324       rs199959716       rs200144732       rs200161417       rs200175700       rs200188532       rs200211031       rs200240346       rs200367748       rs200388725       rs200397730       rs200633805       rs200818153       rs200856862       rs201021286       rs201034407       rs201382126       rs201388394       rs201685363       rs201690723       rs201727948       rs201801737       rs201846893       rs202082263       rs202196654       rs367543931       rs367817442       rs368121242       rs368181945       rs368264864       rs368693516       rs368830174       rs369018417       rs369109378       rs369225651       rs369423988       rs369696164       rs369850875       rs370049457       rs370214447       rs370473435       rs370880759       rs370984239       rs371446894       rs371601781       rs371715795       rs371856235       rs372580114       rs372951844       rs373189696       rs373233085       rs373241441       rs373310094       rs373482948       rs373639133       rs374045249       rs374109517       rs374361726       rs374614472       rs374634843       rs374914079       rs374937847       rs375104781       rs375149435       rs375300237       rs375420925       rs375590904       rs375872977       rs375936783       rs376036856       rs376567380       rs376574386       rs376651440       rs376992312       rs377048179       rs377323259       rs377464703       rs527360728       rs527424785       rs527902219       rs528025586       rs528259941       rs528363581       rs528376259       rs528451441       rs528554403       rs529040821       rs529615111       rs529630664       rs529718596       rs529837619       rs530184957       rs530696578       rs530782926       rs530810845       rs530816616       rs530895130       rs530959643       rs531910928       rs532064654       rs532282113       rs532504340       rs532508885       rs533169844       rs533170622       rs533249551       rs533297153       rs533485839       rs533691919       rs533700185       rs533900576       rs534000212       rs534270071       rs534357725       rs534377139       rs534828848       rs534960363       rs535419219       rs535433064       rs535499614       rs535771245       rs535800688       rs535920248       rs535975531       rs535983035       rs536191464       rs536997750       rs537005549       rs537196120       rs537665023       rs538173999       rs538205338       rs538262788       rs538399395       rs538458216       rs538587758       rs538823255       rs538975739       rs539401395       rs539421372       rs539463252       rs539533855       rs539792708       rs539841794       rs539968580       rs540172011       rs540298978       rs540346706       rs540408368       rs540507819       rs541024230       rs541812928       rs542262251       rs542372790       rs542445854       rs542521353       rs542600597       rs542656692       rs542837078       rs543058665       rs543116903       rs543572462       rs543659644       rs543795677       rs543809726       rs543962768       rs544020153       rs544062300       rs544127693       rs544303654       rs544752855       rs545296722       rs545326812       rs545833694       rs545920695       rs545958292       rs546027456       rs546259318       rs546379708       rs546413402       rs546497562       rs547103274       rs547568213       rs547774481       rs547777227       rs547915883       rs548030735       rs548103556       rs548177431       rs548530243       rs548743108       rs548773316       rs549079303       rs549193033       rs549205190       rs549266557       rs550186879       rs550229311       rs550397744       rs550397764       rs550534814       rs550540269       rs550586255       rs551434137       rs551434190       rs551591439       rs551605499       rs551667091       rs551711380       rs552086548       rs552704871       rs552874830       rs553003596       rs553756803       rs553784970       rs553837097       rs553846459       rs554455267       rs554654937       rs554739806       rs554750385       rs554935584       rs555379985       rs555410545       rs555731236       rs555981497       rs555983044       rs556199157       rs556502818       rs556573935       rs556638234       rs557176736       rs557182938       rs557742439       rs557905983       rs558307922       rs558371096       rs558384191       rs558975978       rs559178331       rs559367052       rs559616211       rs559677328       rs559705716       rs559764057       rs559810368       rs559943155       rs560011194       rs560142343       rs560403027       rs560541364       rs560929436       rs560982680       rs560991124       rs561173734       rs561737904       rs561801259       rs562190945       rs562250367       rs562268078       rs562327133       rs562366862       rs562924700       rs562954819       rs563368679       rs563565046       rs563595331       rs563604507       rs563844645       rs563976843       rs564121404       rs564569678       rs564695290       rs564984479       rs565332111       rs565957514       rs565968513       rs566030568       rs566092892       rs566253706       rs566377459       rs566584441       rs567306470       rs567471316       rs567502463       rs567673106       rs568282941       rs568457082       rs568505094       rs568571621       rs568728127       rs568747445       rs568789190       rs568891620       rs569703345       rs569895135       rs569925296       rs570044407       rs570060443       rs570277914       rs570543889       rs570710721       rs571010700       rs571152278       rs571180951       rs571250615       rs571312798       rs571464686       rs571470120       rs572310288       rs572503904       rs572573821       rs572669001       rs572914694       rs573034966       rs573129140       rs573473193       rs573734253       rs573777728       rs574255387       rs574339118       rs574922498       rs575231428       rs575466065       rs575526849       rs576203241       rs576402507       rs576426120       rs576501637       rs576552739       rs576736742       rs576997563       rs577130810       rs577454470       rs577457925       rs577471392       rs577893909       rs578224588       rs745435637       rs745721846       rs745737333       rs745739936       rs745998072       rs746025770       rs746291317       rs746334385       rs746370635       rs746381324       rs746578511       rs746587906       rs746686648       rs746832341       rs747068435       rs747178598       rs747261020       rs747264532       rs747277084       rs747306531       rs747456599       rs747732347       rs748023036       rs748029750       rs748179719       rs748289886       rs748313502       rs748401080       rs748401301       rs748431676       rs748580332       rs748608780       rs748847842       rs748885927       rs748967483       rs749082609       rs749149477       rs749257214       rs749372057       rs749522330       rs749691763       rs749788679       rs750006764       rs750006980       rs750091031       rs750111269       rs750270946       rs750286713       rs750346014       rs750476367       rs750839217       rs750907774       rs750927289       rs750995820       rs751155056       rs751200163       rs751251131       rs751408144       rs751514928       rs751697456       rs751816771       rs751833156       rs752031627       rs752125896       rs752189070       rs752377619       rs752416471       rs752498028       rs752614628       rs752704647       rs752875321       rs752880061       rs752963369       rs752985574       rs753103917       rs753288293       rs753303800       rs753526867       rs753533983       rs753543367       rs753708255       rs753745002       rs753803341       rs754019172       rs754107778       rs754341186       rs754357643       rs754488965       rs754600582       rs754662703       rs754744779       rs755094245       rs755178150       rs755342300       rs755668403       rs755669893       rs755676448       rs755686914       rs755928091       rs755984072       rs756164570       rs756318122       rs756474582       rs756590422       rs756758796       rs756820819       rs756823119       rs756838851       rs757052304       rs757202058       rs757258805       rs757392118       rs757418187       rs757514124       rs757657442       rs757668971       rs757904461       rs758026586       rs758158483       rs758229069       rs758238488       rs758317552       rs758397188       rs758417370       rs758539595       rs758560208       rs758668776       rs758670757       rs758986186       rs759217290       rs759442714       rs759464898       rs759674452       rs759792688       rs759979238       rs760148408       rs760238746       rs760352145       rs760363094       rs760559342       rs760584688       rs760601062       rs760635065       rs760714761       rs760752330       rs760812898       rs760865583       rs761092445       rs761121898       rs761184370       rs761201027       rs761279135       rs761286296       rs761513761       rs761867024       rs762017479       rs762235451       rs762325365       rs762430434       rs762441300       rs762455655       rs762520521       rs762814219       rs763032491       rs763102255       rs763220861       rs763291276       rs763357512       rs763393286       rs763596300       rs763694709       rs763696156       rs763991302       rs764303362       rs764456472       rs764462444       rs764538821       rs764686057       rs764732017       rs764748115       rs764847572       rs764873431       rs764964046       rs765020096       rs765059441       rs765144512       rs765201116       rs765613043       rs765620831       rs765668595       rs765872491       rs766020877       rs766108531       rs766131515       rs766182952       rs766296817       rs766457780       rs766504022       rs766672907       rs766840370       rs767009828       rs767024152       rs767129998       rs767243556       rs767244596       rs767281024       rs767328933       rs767343516       rs767656745       rs767983709       rs767988002       rs768280600       rs768349018       rs768393112       rs768495613       rs768582234       rs768670325       rs768720671       rs768816440       rs768985311       rs769162880       rs769324500       rs769537958       rs769736652       rs769814669       rs769873215       rs770038490       rs770065631       rs770180598       rs770441614       rs770477877       rs770581595       rs770702993       rs770791767       rs770951543       rs771198323       rs771300997       rs771325514       rs771436228       rs771476412       rs771526185       rs771583982       rs771695948       rs771749891       rs771897556       rs772074554       rs772093900       rs772162515       rs772560851       rs772577268       rs772587819       rs772748867       rs773007857       rs773126065       rs773548267       rs773808192       rs773808215       rs773833513       rs773837286       rs773849559       rs773895110       rs773925637       rs773965924       rs774234600       rs774235889       rs774281968       rs774542407       rs774633851       rs774787263       rs774814607       rs774975841       rs774995891       rs775107841       rs775270447       rs775380634       rs775389426       rs775542682       rs775665408       rs775853397       rs775866618       rs776033314       rs776054961       rs776161540       rs776332947       rs776441039       rs776578834       rs776652546       rs776654744       rs776694567       rs776816111       rs777087568       rs777107432       rs777137667       rs777190098       rs777270662       rs777458937       rs777496999       rs777734915       rs777957260       rs777975671       rs778121904       rs778498583       rs778513407       rs778599678       rs778721195       rs778798515       rs778810095       rs779010627       rs779050541       rs779078797       rs779087511       rs779192574       rs779649315       rs779649346       rs779737181       rs780021840       rs780188934       rs780288143       rs780310299       rs780522762       rs780682130       rs780870836       rs781039900       rs781277177       rs781334421       rs781373539       rs781463860       rs781464201       rs781483854       rs781517341       rs781749452       rs781778694      

RNASEL基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
AGATCTAGAGGACCTTGGAC
58
ACTTTGAGCTTTCAGATCCTC
58
GAGATCTAGAGGACCTTGGAC
59
ACTTTGAGCTTTCAGATCCTC
58
ATCTAGAGGACCTTGGACG
58
TACTTTGAGCTTTCAGATCCTC
58
      尚未收录相关数据

RNASEL基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

RNASEL基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0003723
Q05823(UniProtKB)
IDA
GO:0004521
Q05823(UniProtKB)
NAS
GO:0004672
Q05823(UniProtKB)
IEA
GO:0005515
Q05823(UniProtKB)
IPI
GO:0005524
Q05823(UniProtKB)
IEA
GO:0005575
Q05823(UniProtKB)
ND
GO:0005759
Q05823(UniProtKB)
TAS
GO:0005829
Q05823(UniProtKB)
TAS
GO:0006364
Q05823(UniProtKB)
IEA
GO:0006397
Q05823(UniProtKB)
IEA
GO:0006468
Q05823(UniProtKB)
NAS
GO:0016363
Q05823(UniProtKB)
IEA
GO:0019843
Q05823(UniProtKB)
IEA
GO:0043021
Q05823(UniProtKB)
IEA
GO:0043488
Q05823(UniProtKB)
IEA
GO:0045071
Q05823(UniProtKB)
IDA
GO:0045444
Q05823(UniProtKB)
IEA
GO:0045944
Q05823(UniProtKB)
IDA
GO:0046872
Q05823(UniProtKB)
IEA
GO:0051607
Q05823(UniProtKB)
IDA
GO:0055085
Q05823(UniProtKB)
TAS
GO:0060337
Q05823(UniProtKB)
TAS
GO:0090502
Q05823(UniProtKB)
IEA
GO:2001275
Q05823(UniProtKB)
IEA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控RNASEL基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Prostate cancer, familial 0.36434307 16 6 BeFree_CLINVAR_CTD_human_ORPHANET
Prostatic Neoplasms 0.17194822 21 2 BeFree_CTD_human_GAD_LHGDN
Multiple Sclerosis 0.12 1 1 GWASCAT
Malignant neoplasm of prostate 0.061998501 59 7 BeFree_GAD
Prostate carcinoma 0.014386419 53 4 BeFree
Chronic Fatigue Syndrome 0.006534468 5 0 BeFree_LHGDN
Fatigue 0.005991584 3 0 BeFree_LHGDN
Infection 0.0054487 2 0 LHGDN
Hepatitis C 0.003452799 5 0 BeFree_GAD
Virus Diseases 0.003257302 12 0 BeFree
Malignant neoplasm of breast 0.003181358 3 2 BeFree_GAD
Colorectal Cancer 0.003181358 3 4 BeFree_GAD
West Nile viral infection 0.002909916 2 0 BeFree_GAD
Hereditary Nonpolyposis Colorectal Neoplasms 0.00272435 1 0 LHGDN
Pancreatic Neoplasm 0.00272435 1 0 LHGDN
ovarian neoplasm 0.00272435 1 0 LHGDN
Malignant neoplasm of lung 0.002638474 2 0 BeFree_GAD
Malignant neoplasm of pancreas 0.002638474 1 0 BeFree_GAD
Alzheimer's Disease 0.002367032 1 0 GAD
Biliary Tract Neoplasm 0.002367032 1 0 GAD
Malignant neoplasm of urinary bladder 0.002367032 1 0 GAD
Inflammation 0.002367032 1 0 GAD
Chronic Obstructive Airway Disease 0.002367032 1 0 GAD
Colorectal Carcinoma 0.000814326 3 4 BeFree
Myeloid Leukemia, Chronic 0.000814326 3 0 BeFree
Hereditary pancreatitis 0.000814326 3 0 BeFree
Cervix carcinoma 0.000814326 3 0 BeFree
Carcinogenesis 0.000814326 3 2 BeFree
Breast Carcinoma 0.000814326 3 2 BeFree
Malignant tumor of cervix 0.000542884 2 0 BeFree
Hepatitis 0.000542884 2 0 BeFree
Hepatitis A 0.000542884 2 0 BeFree
Obesity 0.000542884 2 0 BeFree
Benign Prostatic Hyperplasia 0.000542884 2 0 BeFree
Malignant tumor of colon 0.000271442 1 0 BeFree
Squamous cell carcinoma 0.000271442 1 0 BeFree
Dengue Fever 0.000271442 1 0 BeFree
Liver neoplasms 0.000271442 1 0 BeFree
Reticulosarcoma 0.000271442 1 0 BeFree
Pyruvate Carboxylase Deficiency Disease 0.000271442 1 0 BeFree
Diffuse Large B-Cell Lymphoma 0.000271442 1 0 BeFree
Malignant neoplasm of gallbladder 0.000271442 1 0 BeFree
Gallbladder Carcinoma 0.000271442 1 0 BeFree
Pancreatic carcinoma 0.000271442 1 0 BeFree
Carcinoma of ampulla of Vater 0.000271442 1 0 BeFree
Vesicular Stomatitis 0.000271442 1 0 BeFree
Multiple polyps 0.000271442 1 2 BeFree
Histiocytic sarcoma 0.000271442 1 0 BeFree
Hepatitis C, Chronic 0.000271442 1 0 BeFree
Squamous cell carcinoma of skin 0.000271442 1 0 BeFree
Carcinoma of lung 0.000271442 1 0 BeFree
Skin carcinoma 0.000271442 1 0 BeFree
Metastatic Prostate Carcinoma 0.000271442 1 7 BeFree
Hereditary Nonpolyposis Colorectal Cancer 0.000271442 1 4 BeFree
Liver carcinoma 0.000271442 1 0 BeFree
Pancreatic carcinoma, familial 0.000271442 1 2 BeFree
Hereditary Prostate Carcinoma 0.000271442 1 0 BeFree
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