RNASE4(ribonuclease, RNase A family, 4)

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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14q11
基因染色体位置图

The protein encoded by this gene belongs to the pancreatic ribonuclease family. It plays an important role in mRNA cleavage and has marked specificity towards the 3' side of uridine nucleotides. Alternative splicing results in four transcript variants encoding the same protein. This gene and the gene that encodes angiogenin share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Aug 2013]

[中文简述(自动翻译):]  由该基因编码的蛋白质属于胰核糖核酸酶家族。它起着mRNA切割中起重要作用,并具有显着朝尿苷核苷酸的3‘侧的特异性。在四个转录剪接的结果变体编码相同的蛋白质。该基因和其编码血管生成份额的启动子和5‘外显子的基因。每个基因拼接到包含其完整的编码区的独特的外显子的下游。 [由RefSeq的,2013年8月提供]

RNASE4基因的碱基序列:[NCBI]
RNASE4基因的碱基突变:           显示全部snp
rs11701       rs17560       rs1010458       rs1010459       rs1010460       rs1010461       rs2228653       rs2319381       rs2319382       rs2319383       rs4470055       rs4609747       rs4619306       rs4982319       rs4982325       rs4982326       rs4982327       rs5019558       rs6571340       rs7143451       rs7143619       rs7144863       rs7145463       rs7151470       rs8003273       rs8004382       rs8008227       rs8008440       rs9322855       rs10138475       rs10149793       rs10220701       rs11156631       rs11541242       rs11629401       rs11851044       rs12100929      
rs12434011       rs12881261       rs12887373       rs12895066       rs17114633       rs17114671       rs17114699       rs17242776       rs17516133       rs28589501       rs34121942       rs34282815       rs34838025       rs34921147       rs34977187       rs36071889       rs36091065       rs45525731       rs45591635       rs57864476       rs58132820       rs61976879       rs61976880       rs72659972       rs72659976       rs73572297       rs74472119       rs74606063       rs74792371       rs74809902       rs75123596       rs75343336       rs75668394       rs76478018       rs76758305       rs77628263       rs77753814       rs78376391       rs78937665       rs79163862       rs79377029       rs111700190       rs112875279       rs112887595       rs113043546       rs113062328       rs113563340       rs113950902       rs114773250       rs114955901       rs115011300       rs115156442       rs115180442       rs115598918       rs115726927       rs116127371       rs116812055       rs117053048       rs117054931       rs117362930       rs117453218       rs117466368       rs117592031       rs117669481       rs117684010       rs117730041       rs117787610       rs117926213       rs117978329       rs118103074       rs121909536       rs121909541       rs121909542       rs121909543       rs137953457       rs138117719       rs138175896       rs138375023       rs138580116       rs139608804       rs139732426       rs139861671       rs140007611       rs140348700       rs140507146       rs140987355       rs141055235       rs141200372       rs141398857       rs142205958       rs142443131       rs142457415       rs143728392       rs143739765       rs144376159       rs144489136       rs144555424       rs145436253       rs145497941       rs145565348       rs145714910       rs145979665       rs146116002       rs146252785       rs146363199       rs146485834       rs146544087       rs146849858       rs146973333       rs146989724       rs147128108       rs147613121       rs147701713       rs148266086       rs148417923       rs148786659       rs148905586       rs148942933       rs149147430       rs149304927       rs149672657       rs149763105       rs149815387       rs150229666       rs150284406       rs150754819       rs180750198       rs180751385       rs181045690       rs181271849       rs181419958       rs182124765       rs182128461       rs182484790       rs182701915       rs182965303       rs183191317       rs183246475       rs183575342       rs183814652       rs184046218       rs184297073       rs184674274       rs184963428       rs185822164       rs185835072       rs185934609       rs186097365       rs186381273       rs187029295       rs187214991       rs188398460       rs188458732       rs188978443       rs189202844       rs189368456       rs189491866       rs190012637       rs190194733       rs190733042       rs190817770       rs190832693       rs190840536       rs191077642       rs191115818       rs191369960       rs191644287       rs191910613       rs191983929       rs192675097       rs192776561       rs193086968       rs199509897       rs199609607       rs199814372       rs199849853       rs199911443       rs200240901       rs200507487       rs201068740       rs201135457       rs201376912       rs201878808       rs367569683       rs368140290       rs368255675       rs368734981       rs368865155       rs369021947       rs369214577       rs371797330       rs371879733       rs371992400       rs372622387       rs372839164       rs373246662       rs373246782       rs373324416       rs373669465       rs374332721       rs374766597       rs375123012       rs375234576       rs375882705       rs377472145       rs397760187       rs527406133       rs527790227       rs527790887       rs527907357       rs527982125       rs528220512       rs528271809       rs528727420       rs528805279       rs529253038       rs529395078       rs529825486       rs530263454       rs530299735       rs530303074       rs530335126       rs530603328       rs530688028       rs530717465       rs531157480       rs531238645       rs531330406       rs531583796       rs531804374       rs531906918       rs531934004       rs532209368       rs532250342       rs532250612       rs532667850       rs532701199       rs533026567       rs533162959       rs533512812       rs534005458       rs534036444       rs534124478       rs534301227       rs534674126       rs534763815       rs534847371       rs535311762       rs535836124       rs536799136       rs537266601       rs537710359       rs537748610       rs538175793       rs538220114       rs538226200       rs538308017       rs538614189       rs538698813       rs538733608       rs539098577       rs539720690       rs540202898       rs540355511       rs540552538       rs540565980       rs541085173       rs541556624       rs541826945       rs542105742       rs542112339       rs542339286       rs542458460       rs542551453       rs542587461       rs542631608       rs543033920       rs543038269       rs543547405       rs543926921       rs544090977       rs544325084       rs544359710       rs544442461       rs544578047       rs545022755       rs545059182       rs545622644       rs545798052       rs545959235       rs546134254       rs546317379       rs546435629       rs546518379       rs546792502       rs546936827       rs547405309       rs547894081       rs548780962       rs548914579       rs549574261       rs549644420       rs550007170       rs550119689       rs550170988       rs550371808       rs550564167       rs550689462       rs550857372       rs550864873       rs550900198       rs551172310       rs551295345       rs552701315       rs553125029       rs553299584       rs553429701       rs553513710       rs553689296       rs553934516       rs554154902       rs554631109       rs554824296       rs554968728       rs555033842       rs555069870       rs555162051       rs555346515       rs555686536       rs555996296       rs556084003       rs556327323       rs556397601       rs556481517       rs556980896       rs557007930       rs557019430       rs558472017       rs558802008       rs558838604       rs559058784       rs559370219       rs559575660       rs559742403       rs559933707       rs560132718       rs560964694       rs561004785       rs561298954       rs561493607       rs561821547       rs562016394       rs562144321       rs562550675       rs562582388       rs562891168       rs563139057       rs563184930       rs563220994       rs563307691       rs563697133       rs563974817       rs564195248       rs564314743       rs564482222       rs564505733       rs564592763       rs564717772       rs564992090       rs565256089       rs565444731       rs565899528       rs565990470       rs566790296       rs566979141       rs567000261       rs567011311       rs567075943       rs567201782       rs567288670       rs567495131       rs567972766       rs568152175       rs568279441       rs568359456       rs568909998       rs569183483       rs569187751       rs569346622       rs569467185       rs569592039       rs570064184       rs570381480       rs570775661       rs570796859       rs570897297       rs570899701       rs571259903       rs571424605       rs571503657       rs571691877       rs572113743       rs572142151       rs572708695       rs572785011       rs573024590       rs573061421       rs573184863       rs573335661       rs574146777       rs574176035       rs574681383       rs574800743       rs575051760       rs575262035       rs575585200       rs575745279       rs575941167       rs577105908       rs577138365       rs577139712       rs578045401       rs745769575       rs746187039       rs746741466       rs746829799       rs746835738       rs747227363       rs747686507       rs747847790       rs748667494       rs749308574       rs749844944       rs751353259       rs751781877       rs752759936       rs752801394       rs753565970       rs754593656       rs755200671       rs755827967       rs756137289       rs758336427       rs758351505       rs758743573       rs759928848       rs760854021       rs761341937       rs761913537       rs761921842       rs762965174       rs763580010       rs764224898       rs764243399       rs765687456       rs765709767       rs766131151       rs766649220       rs767653234       rs767709995       rs768342067       rs768490521       rs768899582       rs769750815       rs769960079       rs770267842       rs770801799       rs770840869       rs771332480       rs771741570       rs771940687       rs771982718       rs772822451       rs773237991       rs773360024       rs774017767       rs774292967       rs774955064       rs775737328       rs776697501       rs777431370       rs778121390       rs778252755       rs778543068       rs779244277       rs779304641       rs779836840       rs779928407       rs780547000       rs781183678       rs869111110       rs3094       rs944438       rs1888560       rs1888561       rs1888562       rs1999343       rs2873964       rs3748338       rs4982335       rs7155477       rs7160116       rs7161023       rs8005306       rs8010599       rs10625796       rs11541061       rs11628774       rs12893068       rs17114743       rs17114745       rs17211649       rs17211656       rs17242783       rs17242790       rs34394955       rs34825966       rs35764991       rs45592336       rs55643105       rs56094440       rs59543367       rs72659992       rs74034360       rs76158095       rs76529908       rs76986166       rs77810283       rs78113061       rs78160595       rs79236215       rs80107387       rs111424862       rs111584577       rs112970813       rs114564543       rs115069247       rs115601653       rs116354284       rs116927401       rs117213150       rs117582758       rs117613952       rs117731651       rs117931725       rs138521344       rs138916480       rs139065075       rs139163892       rs139852513       rs140751705       rs140764840       rs140827896       rs140911497       rs140987956       rs141647314       rs142040605       rs143247343       rs143519313       rs143622835       rs143629764       rs143808228       rs144109636       rs144146051       rs144616272       rs144746602       rs144859809       rs145062531       rs145370834       rs146528738       rs146666841       rs147243967       rs147250189       rs148539505       rs148642430       rs149640495       rs149951595       rs150462802       rs151144001       rs151192368       rs181003524       rs181291985       rs181878775       rs182349795       rs183059597       rs183269108       rs183558991       rs185231019       rs185283107       rs185631178       rs186345989       rs186461164       rs186662256       rs187162901       rs187354537       rs188869432       rs189391171       rs189625630       rs189761158       rs190017766       rs190312398       rs190854284       rs191115230       rs191649751       rs191663589       rs192514367       rs192953490       rs200888523       rs368106594       rs368982058       rs369987673       rs370454942       rs370506839       rs370568027       rs370954171       rs374269522       rs374763160       rs375477062       rs376084203       rs528642633       rs529074139       rs531071568       rs531286817       rs532574894       rs532941379       rs533026559       rs534669211       rs534833191       rs536110868       rs536149508       rs536583842       rs536672596       rs537180777       rs538190800       rs538529534       rs539036677       rs539076082       rs539471812       rs540956970       rs541041278       rs541432920       rs542372918       rs542427723       rs542944146       rs543459956       rs544205687       rs545285179       rs545888702       rs547155241       rs549055455       rs549259098       rs549637880       rs549754245       rs550031462       rs550781270       rs551047752       rs551137180       rs551296377       rs552960263       rs554454850       rs554843941       rs554880766       rs555309622       rs556712112       rs557900615       rs557979501       rs559008080       rs560508301       rs561182375       rs561270427       rs561571578       rs563451470       rs564240929       rs564445254       rs564500195       rs564512618       rs564905921       rs564992442       rs565445075       rs565508787       rs565988169       rs566385208       rs566869173       rs567433345       rs567520488       rs567817404       rs569261644       rs569663895       rs570068920       rs570548224       rs570657053       rs571257873       rs571581594       rs571721972       rs572365309       rs572469899       rs572748081       rs573683944       rs573771161       rs575034480       rs575413553       rs575534495       rs576448213       rs576831432       rs577332135       rs577473144       rs745575862       rs746434077       rs746611444       rs747525286       rs748161506       rs749054271       rs749496833       rs749582712       rs749980875       rs751540914       rs751587240       rs751741459       rs752555339       rs752628625       rs752989996       rs753709563       rs754186891       rs754908062       rs756611890       rs756628253       rs757550038       rs757568118       rs757856041       rs758447979       rs758631329       rs759207684       rs759744209       rs760086522       rs760536517       rs760650221       rs761539367       rs761660859       rs762563523       rs762658222       rs763082995       rs763087802       rs763299958       rs764066337       rs764614442       rs764729138       rs764966365       rs765855486       rs765942285       rs767567791       rs768059553       rs768228660       rs768331262       rs768745751       rs768949635       rs769785872       rs770196299       rs770906300       rs771172614       rs771543461       rs771952196       rs772399740       rs772655748       rs772791260       rs773053178       rs773164607       rs774036206       rs774567010       rs774686962       rs774877335       rs775043672       rs775063092       rs776266884       rs776964017       rs777589960       rs778100811       rs779717316       rs780159412       rs781102058       rs781625059      

RNASE4基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
AACAGCTGGAACCCATCTC
59
CAGTATCTTAGAGGTGCCCAG
59
GAACAAACAGCTGGAACCC
59
TATCTTAGAGGTGCCCAGGA
59
GAACAAACAGCTGGAACCC
59
ATCTTAGAGGTGCCCAGGA
59
CGTACTAGGGAGGAAGAAGC
59
ATCAGTATCTTAGAGGTGCCTC
59
ACCTAGATGCAAAGCAGGA
58
AGTATCTTAGAGGTGCCCG
58
CCATCATCGTACTAGGGAGG
58
ATCAGTATCTTAGAGGTGCCTC
59
GTACTAGGGAGGAAGAAGCG
59
ATCAGTATCTTAGAGGTGCCTC
59
CACCTAGATGCAAAGCAGG
58
AGTATCTTAGAGGTGCCCG
58
CCACCTAGATGCAAAGCAG
58
AGTATCTTAGAGGTGCCCG
58
      尚未收录相关数据

RNASE4基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

RNASE4基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0003676
P34096(UniProtKB)
IEA
GO:0004519
P34096(UniProtKB)
IBA
GO:0004522
P34096(UniProtKB)
NAS
GO:0004540
P34096(UniProtKB)
IBA
GO:0005576
P34096(UniProtKB)
IDA
GO:0006379
P34096(UniProtKB)
NAS
GO:0070062
P34096(UniProtKB)
IDA
GO:0090502
P34096(UniProtKB)
IEA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控RNASE4基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Liver Cirrhosis, Experimental 0.12 1 0 CTD_human
Prostatic Neoplasms 0.12 1 0 CTD_human
Obesity 0.002367032 1 0 GAD
Spinal Muscular Atrophy 0.000271442 1 0 BeFree
Erythropoietic Protoporphyria 0.000271442 1 0 BeFree
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