RNASE3(ribonuclease, RNase A family, 3)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

14q11.2
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014]

[中文简述(自动翻译):]  由该基因编码的蛋白质属于胰核糖核酸酶家族，核糖核酸酶A家族的子集。蛋白质显示出对致病细菌的抗菌活性通过的RefSeq，2014年10月提供]

OMIM数据库中对RNASE3基因的介绍     Wikipedia数据库中对RNASE3基因的介绍

基因序列

基因序列

RNASE3基因的碱基序列：[NCBI]

基因突变

基因突变

RNASE3基因的碱基突变：           显示全部snp
rs1957335       rs2073342       rs2233858       rs2233859       rs2233860       rs2281643       rs2284954       rs3216677       rs8019343       rs11575981       rs12147890       rs28435898       rs28525131       rs28532533       rs35201704       rs58689406       rs61980362       rs73573913       rs75559351       rs76423109       rs76764740       rs111273485       rs111618029       rs112635084       rs112776305       rs114080803       rs114516193       rs115041391       rs115812876       rs116652447       rs116957985       rs116973043       rs117019962       rs117293018       rs117413508       rs117725363       rs118071092      
rs139004485       rs139852467       rs140224611       rs140556531       rs141104135       rs141844353       rs142084658       rs142283974       rs143367850       rs143783614       rs144042562       rs145518643       rs145904137       rs146837487       rs147413155       rs147642716       rs148601585       rs149189886       rs149500970       rs150102555       rs150232577       rs150638511       rs151107727       rs151169198       rs181862417       rs182295829       rs182418195       rs183256768       rs183263194       rs183860442       rs185385317       rs186513196       rs187410936       rs188672404       rs188802084       rs189316749       rs189657603       rs190205877       rs191005188       rs191323095       rs192560566       rs192990175       rs200170777       rs200391742       rs200859756       rs201435792       rs201574905       rs202232277       rs368640624       rs368925772       rs369058042       rs369564860       rs369988476       rs370513666       rs371338819       rs371809756       rs371854422       rs373814928       rs374429664       rs374635539       rs376889485       rs397701594       rs527540682       rs528587048       rs529317061       rs529642031       rs531312128       rs532048397       rs532789075       rs533202480       rs534103750       rs535191796       rs535399652       rs535960209       rs536029888       rs536513883       rs537278077       rs537341999       rs538855535       rs539808551       rs539933052       rs540660200       rs541371361       rs542476813       rs542967319       rs543674499       rs544170292       rs544231262       rs545413536       rs546356437       rs546395976       rs546590195       rs547121764       rs547646006       rs549132652       rs550158770       rs550220192       rs550617783       rs551504194       rs551835516       rs551910575       rs553630492       rs553943912       rs554492453       rs555403976       rs555619242       rs555927746       rs556740561       rs557530686       rs558073026       rs558350504       rs558397403       rs558414093       rs560665623       rs560947714       rs561660328       rs561911095       rs562210283       rs562279804       rs562394008       rs563083375       rs563148497       rs566257690       rs566596536       rs568218077       rs568361815       rs568762072       rs570114626       rs570688677       rs570824109       rs572064220       rs572065181       rs572948356       rs573857829       rs574549966       rs574722196       rs576416624       rs576686682       rs577228595       rs577888509       rs745763770       rs745815779       rs746822072       rs747737990       rs749108905       rs749325429       rs749747826       rs749915196       rs750080650       rs751028512       rs751452048       rs751894020       rs752396079       rs752447332       rs752773252       rs753505935       rs753545273       rs753815870       rs754792205       rs754882987       rs755183918       rs755869829       rs756584165       rs756609160       rs756914512       rs758816325       rs759420664       rs759443996       rs759859690       rs759866259       rs760022580       rs760136393       rs760744021       rs760867669       rs761174292       rs761591198       rs762432943       rs762792315       rs762853405       rs763381382       rs763694164       rs763736238       rs764863313       rs765024971       rs765183900       rs765284714       rs765777874       rs765816453       rs765912597       rs766069912       rs766754949       rs767807631       rs768163273       rs768479364       rs768722970       rs769132450       rs770532968       rs770621900       rs770920342       rs771020920       rs771664674       rs771980152       rs773070454       rs774318039       rs774890961       rs775091856       rs775879390       rs776152400       rs777363353       rs778500694       rs779052723       rs779182743       rs779933714       rs780388883       rs780969165       rs780983963       rs781415785      

基因表达

基因表达

RNASE3基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CAGAGACTGGGAAACATGGT
60
ACTGAGCCCTCGTAAACTG
59
CAGAGACTGGGAAACATGGT
60
TGAGCCCTCGTAAACTGTG
60
TCAGAGACTGGGAAACATGG
60
TGAGCCCTCGTAAACTGTG
60

转录因子

转录因子

      尚未收录相关数据

基因本体信息

RNASE3基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

RNASE3基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0002227
P12724(UniProtKB)
IDA
GO:0003676
P12724(UniProtKB)
IEA
GO:0004519
P12724(UniProtKB)
IBA
GO:0004540
P12724(UniProtKB)
TAS
GO:0005576
P12724(UniProtKB)
TAS
GO:0005615
P12724(UniProtKB)
IDA
GO:0006401
P12724(UniProtKB)
TAS
GO:0019731
P12724(UniProtKB)
IDA
GO:0050830
P12724(UniProtKB)
IDA
GO:0070062
P12724(UniProtKB)
IDA
GO:0090501
P12724(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控RNASE3基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Asthma 0.143708708 19 0 BeFree_CTD_human_GAD_LHGDN
Gram-Negative Bacterial Infections 0.12 1 0 CTD_human
Gram-Positive Bacterial Infections 0.12 1 0 CTD_human
Dermatitis, Atopic 0.005905708 5 0 BeFree_GAD_LHGDN
Allergic rhinitis (disorder) 0.003452799 4 0 BeFree_GAD
Nasal Polyps 0.003267234 3 0 BeFree_LHGDN
Eosinophilia 0.002909916 2 0 BeFree_GAD
Airway Obstruction 0.00272435 1 0 LHGDN
Churg-Strauss Syndrome 0.00272435 1 0 LHGDN
Milk Hypersensitivity 0.00272435 1 0 LHGDN
Squamous cell carcinoma 0.002638474 1 0 BeFree_GAD
Eosinophilia, Tropical 0.002638474 1 0 BeFree_GAD
Embolism 0.002367032 1 0 GAD
Mouth Neoplasms 0.002367032 1 0 GAD
Neoplasm Invasiveness 0.002367032 1 0 GAD
Neoplasm Recurrence, Local 0.002367032 1 0 GAD
Schistosomiasis 0.002367032 1 0 GAD
Eczema 0.000814326 3 0 BeFree
Craniosynostosis 0.000542884 2 0 BeFree
Virus Diseases 0.000542884 2 0 BeFree
Eosinophilic disorder 0.000542884 2 0 BeFree
Disorder characterized by eosinophilia 0.000542884 2 0 BeFree
Anemia 0.000271442 1 0 BeFree
Bronchiolitis 0.000271442 1 0 BeFree
Malaria 0.000271442 1 0 BeFree
Malaria, Cerebral 0.000271442 1 0 BeFree
Otitis Media with Effusion 0.000271442 1 0 BeFree
Pneumonia 0.000271442 1 0 BeFree
Rhinitis 0.000271442 1 0 BeFree
Schistosomiasis mansoni 0.000271442 1 0 BeFree
Status Asthmaticus 0.000271442 1 0 BeFree
Wheezing 0.000271442 1 0 BeFree
Bronchial Hyperreactivity 0.000271442 1 0 BeFree
Allergic asthma 0.000271442 1 0 BeFree
Erythropoietic Protoporphyria 0.000271442 1 0 BeFree
Nose symptoms 0.000271442 1 0 BeFree
Aspirin-sensitive asthma with nasal polyps 0.000271442 1 0 BeFree
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site 0.000271442 1 0 BeFree
pricking of skin 0.000271442 1 0 BeFree
Acute asthma 0.000271442 1 0 BeFree
allergic symptom 0.000271442 1 0 BeFree
Bacterial sinusitis 0.000271442 1 0 BeFree
Pleuropulmonary blastoma 0.000271442 1 0 BeFree
Allergic sensitization 0.000271442 1 0 BeFree

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