RLN1(relaxin 1)

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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9p24.1
基因染色体位置图

Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. [provided by RefSeq, Jan 2013]

[中文简述(自动翻译):]  松弛素是已知的内分泌和自分泌/旁分泌激素,属于胰岛素基因超家族。在人类有三种非等位基因的松弛素基因,RLN1,RLN2和RLN3,其中RLN1和RLN2分享高序列同源性。由该基因编码的蛋白质被合成为一种单链多肽,但活性形式由一个A链和由二硫键连接的B链。松弛素是由卵巢产生,并且针对哺乳动物生殖系统成熟宫颈,拉长耻骨联合,抑制子宫收缩。它可能有增强精子活力,调节血压,控制心脏率和释放催产素和血管加压素其他角色。 [由RefSeq的,2013年1月提供]

RLN1基因的碱基序列:[NCBI]
RLN1基因的碱基突变:           显示全部snp
rs471037       rs471068       rs533649       rs999060       rs1322220       rs1407386       rs1407387       rs1407388       rs1575277       rs1853218       rs1853219       rs1853220       rs1885495       rs1885496       rs1885497       rs1885498       rs1885499       rs2025169       rs2146074       rs2146075       rs2181145       rs2273782       rs2273784       rs2890629       rs3758240       rs4119229       rs4278200       rs4740810       rs4742078       rs4742079       rs4742080       rs4742081       rs6476961       rs6476962       rs7021193       rs7022239       rs7027672      
rs7034408       rs7034440       rs7035195       rs7035226       rs7039729       rs7044690       rs7047608       rs7469056       rs7848509       rs7849015       rs7857208       rs7858028       rs7858347       rs7861799       rs7863534       rs7871658       rs9695268       rs10116687       rs10117651       rs10125965       rs10435742       rs10491649       rs10758680       rs10815179       rs10815180       rs10815181       rs10975050       rs10975051       rs10975052       rs10975053       rs10975056       rs11551507       rs11793069       rs11794994       rs12056968       rs12338169       rs12344125       rs12350801       rs12379219       rs12551269       rs12554802       rs12686525       rs13297190       rs28446653       rs28698164       rs28713722       rs28731244       rs28850909       rs34612061       rs34807596       rs35088261       rs35316688       rs35426888       rs36123525       rs55930144       rs56059921       rs56235721       rs56996481       rs57244573       rs57702698       rs58504459       rs58618579       rs58968405       rs59441173       rs60035170       rs60299004       rs60509036       rs60735956       rs60970474       rs61236751       rs61401592       rs61706845       rs62557692       rs62638697       rs62638699       rs71326155       rs71487818       rs71498612       rs71498613       rs71501824       rs72499174       rs72499177       rs72703640       rs72703642       rs72703643       rs73393279       rs73393298       rs73639273       rs73639274       rs73639275       rs73639276       rs73639277       rs73639280       rs73639281       rs73639282       rs73639283       rs73639284       rs73639285       rs74700624       rs74788005       rs75312080       rs75456823       rs75679551       rs75823265       rs75825221       rs75843765       rs75885289       rs75888755       rs76094482       rs76236605       rs76430768       rs76636506       rs77128935       rs77263015       rs77377004       rs77511300       rs77544638       rs77590258       rs77631500       rs77737536       rs77987980       rs78233390       rs78256401       rs78360441       rs78866167       rs78902181       rs78954328       rs79084029       rs79422873       rs79560191       rs79783091       rs79946857       rs80035372       rs80096720       rs111280743       rs111285678       rs111749225       rs112318888       rs112362150       rs112434221       rs112482782       rs112737453       rs112884465       rs112891388       rs112894861       rs113097864       rs113156672       rs113192310       rs113324264       rs113462224       rs113482561       rs113553897       rs113623304       rs113678308       rs113723760       rs113837013       rs113870563       rs113940017       rs114011611       rs114056771       rs114287053       rs114294517       rs114443623       rs114559138       rs114560436       rs114682761       rs114816081       rs114950602       rs114953834       rs115194072       rs115197490       rs115362875       rs115386103       rs115443988       rs115468882       rs115473740       rs115599022       rs115660015       rs115663263       rs115835974       rs115868004       rs116012717       rs116283232       rs116497035       rs116551306       rs116933160       rs116994310       rs117088331       rs117191534       rs117367979       rs117586430       rs117898870       rs137858312       rs137992378       rs138002200       rs138051943       rs138075606       rs138117283       rs138320356       rs138324551       rs138380404       rs138563276       rs138614296       rs138680945       rs138711065       rs138715549       rs138733330       rs138930259       rs138938965       rs138999736       rs139130724       rs139197046       rs139294857       rs139341724       rs139484586       rs139517054       rs139584640       rs139617189       rs139674544       rs139697631       rs139762226       rs139830980       rs140073699       rs140220176       rs140350306       rs140417241       rs140467511       rs140570837       rs140610906       rs140680082       rs140721558       rs140777349       rs140954536       rs141018307       rs141056958       rs141101090       rs141122826       rs141177954       rs141422581       rs141474261       rs141794512       rs141938641       rs142061683       rs142076110       rs142124284       rs142125368       rs142193566       rs142238288       rs142264769       rs142414023       rs142504109       rs142508802       rs142539979       rs142610521       rs142687399       rs142721722       rs142870561       rs142936349       rs143025204       rs143165582       rs143203801       rs143341576       rs143468790       rs143582652       rs143583034       rs143649891       rs143727400       rs143938299       rs143984444       rs144018475       rs144048426       rs144118124       rs144197235       rs144241669       rs144272606       rs144374461       rs144536191       rs144679740       rs144749958       rs144771394       rs144813485       rs144826128       rs144879941       rs144937778       rs145070573       rs145158543       rs145525345       rs145548946       rs145563561       rs145609606       rs145771544       rs145786158       rs145822419       rs145835654       rs145837313       rs145863164       rs145897083       rs145911528       rs145942579       rs145943581       rs145961506       rs146225836       rs146306135       rs146344587       rs146362685       rs146365261       rs146476202       rs146513762       rs146549416       rs146649730       rs146688786       rs146770443       rs146930778       rs146947713       rs147296781       rs147319958       rs147336859       rs147424954       rs147441093       rs147545748       rs147602636       rs147633216       rs147706831       rs147723185       rs147810731       rs147827098       rs147963253       rs147986729       rs148148197       rs148181164       rs148291364       rs148339575       rs148394367       rs148516714       rs148583914       rs148603537       rs148655019       rs148724705       rs148777211       rs148903475       rs148923143       rs148936801       rs148974832       rs149042947       rs149069258       rs149253729       rs149275193       rs149435419       rs149524022       rs149545634       rs149627613       rs149643915       rs149681610       rs149752411       rs149803606       rs150015848       rs150140803       rs150260966       rs150279376       rs150402302       rs150420654       rs150492805       rs150581246       rs150600191       rs150668925       rs150720715       rs150880724       rs150939525       rs150988218       rs151041280       rs151201127       rs151321389       rs180681656       rs180687554       rs180693632       rs180921529       rs180948882       rs180955540       rs180955670       rs180990239       rs181138927       rs181144362       rs181233922       rs181245647       rs181262613       rs181483372       rs181604643       rs181615482       rs181772266       rs181795884       rs181870246       rs181883181       rs182038245       rs182065605       rs182078187       rs182231820       rs182572608       rs182601637       rs182637130       rs182687972       rs182703278       rs182895507       rs182920627       rs183061811       rs183066690       rs183173233       rs183194301       rs183216241       rs183420531       rs183762573       rs183765543       rs183814035       rs184055989       rs184237447       rs184287679       rs184349697       rs184351742       rs184355969       rs184643344       rs184731971       rs184788312       rs184815396       rs184819486       rs184845752       rs184876542       rs185337872       rs185342962       rs185579449       rs185585292       rs185594342       rs185690950       rs185705774       rs186039742       rs186047267       rs186185993       rs186329292       rs186330833       rs186337664       rs186353085       rs186491502       rs186497969       rs186615189       rs186624527       rs186716413       rs186729773       rs186956907       rs186985916       rs186989980       rs186993119       rs187025605       rs187233448       rs187289901       rs187359233       rs187497282       rs187546584       rs187547539       rs187553585       rs187587297       rs188069694       rs188189270       rs188234177       rs188327643       rs188345036       rs188433233       rs188445414       rs188470016       rs188556486       rs188585853       rs188586818       rs188589067       rs188590175       rs188848611       rs188854721       rs188868939       rs188897702       rs189089364       rs189096521       rs189097276       rs189335516       rs189363547       rs189375295       rs189378469       rs189397265       rs189599683       rs189607337       rs189616269       rs189633015       rs189654500       rs189840741       rs189850848       rs189914203       rs190115897       rs190123807       rs190415974       rs190425192       rs190499419       rs190533120       rs190641307       rs190659154       rs190667172       rs190909533       rs191041213       rs191043293       rs191081966       rs191141445       rs191201286       rs191205598       rs191258718       rs191466870       rs191724807       rs191740996       rs191753263       rs191755525       rs191780747       rs191922763       rs191925911       rs191977199       rs192007996       rs192262933       rs192270297       rs192302476       rs192433291       rs192470723       rs192484423       rs192490615       rs192549413       rs192690277       rs192770195       rs192839428       rs192908822       rs192940976       rs192955464       rs193083066       rs193184952       rs193245486       rs199960272       rs200040297       rs200265055       rs200348324       rs200387461       rs200563966       rs201089402       rs201515257       rs201582837       rs202023998       rs367700423       rs367855585       rs367864928       rs368103769       rs368542609       rs368595655       rs368864540       rs368925357       rs369236293       rs369448766       rs369532231       rs369616777       rs370096694       rs370632195       rs370893296       rs371042734       rs371390590       rs371394654       rs371537460       rs371742833       rs371777701       rs371851858       rs372307726       rs372453403       rs372854927       rs373488708       rs373523772       rs373546096       rs374757456       rs374788646       rs375316567       rs375438712       rs375448117       rs376025600       rs376129010       rs376227406       rs376306030       rs376479792       rs376818446       rs376970406       rs377003639       rs377207357       rs377448599       rs397780021       rs527269498       rs527287757       rs527408853       rs527435776       rs527508549       rs527515088       rs527724003       rs527748990       rs527880260       rs527886237       rs528041729       rs528272096       rs528358076       rs528699288       rs528731235       rs528921395       rs528922462       rs528937266       rs529056867       rs529071509       rs529309580       rs529393710       rs529443397       rs529717368       rs529843249       rs529866248       rs529961793       rs529978116       rs530028191       rs530085970       rs530104802       rs530156876       rs530190916       rs530309217       rs530412021       rs530457232       rs530484046       rs530540062       rs530542348       rs530601212       rs531069442       rs531251731       rs531260591       rs531280674       rs531281057       rs531414266       rs531830174       rs531978431       rs532157384       rs532249071       rs532281368       rs532325544       rs532327179       rs532405955       rs532456463       rs532472887       rs532567169       rs532596953       rs532610892       rs532751045       rs532753893       rs532804479       rs532830529       rs532988064       rs533140665       rs533188567       rs533342234       rs533364667       rs533379138       rs533399439       rs533558947       rs533745276       rs533872410       rs533919282       rs533940204       rs534006649       rs534276308       rs534330912       rs534458238       rs534523295       rs534577967       rs535011640       rs535147867       rs535165561       rs535245082       rs535394956       rs535475651       rs535498890       rs535613401       rs535629922       rs535713839       rs535795836       rs535860191       rs535872555       rs536111317       rs536291242       rs536382736       rs536400631       rs536408328       rs536439836       rs536456335       rs536466294       rs536468286       rs536694378       rs536794520       rs536843323       rs536893322       rs536922440       rs536980957       rs537058472       rs537571333       rs537600861       rs537642681       rs537661804       rs537804618       rs537888452       rs537994338       rs538267889       rs538375475       rs538641318       rs538771545       rs538796049       rs538857122       rs539038263       rs539048377       rs539068891       rs539105419       rs539113209       rs539222794       rs539319698       rs539460195       rs539664548       rs539921338       rs540197804       rs540221740       rs540417859       rs540424275       rs540653470       rs540812610       rs540827121       rs540893586       rs541160110       rs541196207       rs541253000       rs541365972       rs541447336       rs541484464       rs541545533       rs541647318       rs541773959       rs541784890       rs541840638       rs541959223       rs542137747       rs542206009       rs542375660       rs542384378       rs542470267       rs542595186       rs542620162       rs542733985       rs542800263       rs542919114       rs542968434       rs542978034       rs542982212       rs543093073       rs543107355       rs543245167       rs543361461       rs543987486       rs544162994       rs544238093       rs544383593       rs544416862       rs544616457       rs544741094       rs544832882       rs544895670       rs544974609       rs545306204       rs545351439       rs545368290       rs545414446       rs545539267       rs545669606       rs545808300       rs545926122       rs546017362       rs546041009       rs546047076       rs546227760       rs546340504       rs546401861       rs546474864       rs546568551       rs546609892       rs546678355       rs546726187       rs546781031       rs546830581       rs546851341       rs546909870       rs546972779       rs547116265       rs547121542       rs547165034       rs547301940       rs547423325       rs547579589       rs547590735       rs547691000       rs548088747       rs548109524       rs548253536       rs548352401       rs548435266       rs548476055       rs548519802       rs548619556       rs548782903       rs548859665       rs549051615       rs549274807       rs549360699       rs549360956       rs549463385       rs549532597       rs549723573       rs549823996       rs549885766       rs549974639       rs549976729       rs550058886       rs550174979       rs550274087       rs550429311       rs550564052       rs550699538       rs550701379       rs550728559       rs550776985       rs550929464       rs551089779       rs551095408       rs551096437       rs551185017       rs551369872       rs551408180       rs551511675       rs552002880       rs552030403       rs552059906       rs552086414       rs552139844       rs552164407       rs552320090       rs552349941       rs552424742       rs552818426       rs553050165       rs553113512       rs553243286       rs553265668       rs553396337       rs553642503       rs553724834       rs553861423       rs553890348       rs553972607       rs554080418       rs554235483       rs554289650       rs554690599       rs554751597       rs554778399       rs554827775       rs554915827       rs555096280       rs555142770       rs555223034       rs555286080       rs555452617       rs555767300       rs555788898       rs555887808       rs555965870       rs556022482       rs556024602       rs556058426       rs556110450       rs556254642       rs556292456       rs556336666       rs556416585       rs556428120       rs556476967       rs556535289       rs556555661       rs556879143       rs557085524       rs557345019       rs557405752       rs557447439       rs557469025       rs557974065       rs557985361       rs558010005       rs558274622       rs558293841       rs558504813       rs558547980       rs558643231       rs558671156       rs558687979       rs558757063       rs558809761       rs558819402       rs558823722       rs559020100       rs559036880       rs559340450       rs559577693       rs559618754       rs559925752       rs559990837       rs560005283       rs560086579       rs560099623       rs560151928       rs560207194       rs560505102       rs560695907       rs560859220       rs560866310       rs561032674       rs561165025       rs561178911       rs561313198       rs561425440       rs561457075       rs561458079       rs561485895       rs561610942       rs561671287       rs561714745       rs561839758       rs561851902       rs561858327       rs562032743       rs562260940       rs562366159       rs562378014       rs562413864       rs562503934       rs562547267       rs562565953       rs562640801       rs562762714       rs562774528       rs562821141       rs562911137       rs562912733       rs562930299       rs562955072       rs563222631       rs563244433       rs563449849       rs563516463       rs563524619       rs563587531       rs563711006       rs563790639       rs563964252       rs564025691       rs564138477       rs564240276       rs564364900       rs564471341       rs564607243       rs564723820       rs564820379       rs564879619       rs564969196       rs565025312       rs565037193       rs565166167       rs565181356       rs565190412       rs565427898       rs565565964       rs565627280       rs565769768       rs565920378       rs566109182       rs566240842       rs566254931       rs566280767       rs566526400       rs566592034       rs566758470       rs566779374       rs566782707       rs566844109       rs566863481       rs567005872       rs567095610       rs567235664       rs567299118       rs567396544       rs567550930       rs567577390       rs567718785       rs567780429       rs567780657       rs568032824       rs568038323       rs568170083       rs568193780       rs568197431       rs568346542       rs568906116       rs568942878       rs568995818       rs568997838       rs569166563       rs569208295       rs569361720       rs569405309       rs569543232       rs569569600       rs569644312       rs569781296       rs569927153       rs570041859       rs570128297       rs570288055       rs570356004       rs570368451       rs570377871       rs570478906       rs570545643       rs570600899       rs570738175       rs570766444       rs570823496       rs571192941       rs571199259       rs571318203       rs571329644       rs571487835       rs571519134       rs571668217       rs571670810       rs571853930       rs571948298       rs572024898       rs572180441       rs572231425       rs572266617       rs572385692       rs572462126       rs572471613       rs572590059       rs572667626       rs572755009       rs572775861       rs572803496       rs572866135       rs572932525       rs573020516       rs573116055       rs573181231       rs573195409       rs573224721       rs573280600       rs573374139       rs573392103       rs573624622       rs573784694       rs574013406       rs574103403       rs574268266       rs574331910       rs574612140       rs574788973       rs574801318       rs574848227       rs575162785       rs575263146       rs575419605       rs575444891       rs575492442       rs575617376       rs575679612       rs575704044       rs575718402       rs575781923       rs575914153       rs575944765       rs576003388       rs576149303       rs576442169       rs576503346       rs576607471       rs576694797       rs576784650       rs576827872       rs576918352       rs576966536       rs577032256       rs577043814       rs577137574       rs577197722       rs577395614       rs577482482       rs577541977       rs577771088       rs578000695       rs578018223       rs578058813       rs578169302       rs578199309       rs578235717       rs745785450       rs745899549       rs746338356       rs746584162       rs746672013       rs747185115       rs747200582       rs747811681       rs747991114       rs748011986       rs748282982       rs748669345       rs748927755       rs749276499       rs749449263       rs749530743       rs749994356       rs750297988       rs750510170       rs750670495       rs751154321       rs751503680       rs751746727       rs751960733       rs753065965       rs753388777       rs753669766       rs753910551       rs754344916       rs754398278       rs754676728       rs754860255       rs754979979       rs755353409       rs755868810       rs756675394       rs756734959       rs756901257       rs756935865       rs756954473       rs757298796       rs757445557       rs758408877       rs758462200       rs758627724       rs758664795       rs759479842       rs759504812       rs760079803       rs760272202       rs760571805       rs760768991       rs760968648       rs760998724       rs761326778       rs761650315       rs762109454       rs762496874       rs762596256       rs763648751       rs763703750       rs764362025       rs764553245       rs764635367       rs764652279       rs764935403       rs765009991       rs766136120       rs766541533       rs766767841       rs766939901       rs767216508       rs767612157       rs767689960       rs767897804       rs768077558       rs768577986       rs769584801       rs769659576       rs769717195       rs770070085       rs770246447       rs770445540       rs771147189       rs771342159       rs771513439       rs771560230       rs772002684       rs772741708       rs773526663       rs773638821       rs774289575       rs774537814       rs774686362       rs775200238       rs775217255       rs775351716       rs775517858       rs775691072       rs776019176       rs776401723       rs776486680       rs776834964       rs776859809       rs776930026       rs777106460       rs777237971       rs777329132       rs777682508       rs777803389       rs778842365       rs779047248       rs779164635       rs779788952       rs779852847       rs780561144       rs780649193       rs780703839       rs780819142       rs781073032       rs781684414       rs868016175       rs2273782       rs57244573       rs140610906       rs186993119      

RLN1基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图

RLN1基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

RLN1基因的本位(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0005179
P04808(UniProtKB)
IEA
GO:0005576
P04808(UniProtKB)
IEA
GO:0007165
P04808(UniProtKB)
NAS
GO:0007565
P04808(UniProtKB)
NAS
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控RLN1基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Premature Birth 0.005091382 2 0 GAD_LHGDN
Hyperplasia 0.00272435 1 0 LHGDN
Hypertensive disease 0.00272435 1 0 LHGDN
Prostatic Neoplasms 0.00272435 1 0 LHGDN
Thyroid Neoplasm 0.00272435 1 0 LHGDN
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Germ cell tumor 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Testicular malignant germ cell tumor 0.000271442 1 0 BeFree
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