RHO(rhodopsin)

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

3q21-q24
基因染色体位置图

Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  视网膜色素变性是一种遗传性疾病是西方社会失明的主要原因。它可作为常染色体显性,常染色体隐性,或X连锁隐性疾病。在常染色体显性形式,其包括占全部病例的约25%,家庭的大约30%具有在编码棒状特定感光体蛋白的视紫红质的基因突变。这是跨膜蛋白,其,光激发时,启动视觉转导级联。在这个基因的缺陷也先天性静止性夜盲的原因之一。 [由RefSeq的,2008年7月提供]

RHO基因的碱基序列:[NCBI]
RHO基因的碱基突变:           显示全部snp
rs2410       rs7984       rs2071092       rs2071093       rs2269736       rs2625953       rs2625954       rs2625955       rs2855552       rs2855557       rs2855558       rs3733148       rs3733149       rs3755837       rs6803468       rs6803484       rs11359208       rs12633814       rs28933394       rs29001566       rs35822883       rs55851525       rs55915536       rs55941599       rs56120415       rs56340615       rs58508862       rs60645924       rs62267563       rs72987932       rs73204245       rs73204247       rs73863103       rs74435833       rs74578881       rs75783569       rs77154523      
rs78163008       rs78872255       rs79311890       rs79765751       rs80263713       rs104893770       rs104893773       rs104893774       rs104893783       rs104893788       rs104893791       rs111823780       rs111871140       rs112302797       rs112445170       rs112640710       rs112855188       rs112963101       rs113310993       rs113312341       rs113751838       rs113823926       rs113964897       rs115345357       rs116351742       rs117803086       rs118173887       rs137883686       rs138142023       rs138831590       rs139028150       rs139435571       rs139502149       rs139566602       rs139731264       rs140851495       rs141185480       rs141468335       rs141844397       rs141951118       rs141956356       rs142285818       rs142322202       rs142769113       rs142771862       rs143003934       rs143559914       rs143735182       rs143977825       rs144211117       rs144222821       rs144270441       rs144317206       rs144339478       rs144852771       rs144939863       rs145004306       rs145024369       rs145248729       rs145549270       rs145921862       rs146311684       rs146389280       rs146391463       rs146936681       rs146987110       rs147005807       rs147640435       rs147761866       rs148110888       rs148165044       rs148222991       rs148627764       rs148748781       rs148801522       rs149079952       rs149084537       rs149615742       rs149722668       rs150129519       rs150250946       rs151063543       rs181047668       rs181387582       rs181914973       rs182735834       rs183230830       rs183318466       rs184850373       rs184966973       rs185011073       rs186091794       rs186719544       rs187430296       rs187923166       rs188052820       rs188128858       rs189018030       rs189786911       rs190889142       rs191009602       rs191819667       rs192412661       rs192461600       rs192604199       rs192710452       rs199573532       rs199583468       rs199701338       rs200054443       rs200076128       rs200095648       rs200165530       rs200207070       rs200248198       rs200826498       rs200894277       rs200946638       rs201008735       rs201340914       rs201989308       rs202215179       rs367631575       rs367633279       rs367797677       rs367909246       rs368157839       rs368522974       rs368534414       rs368910470       rs368995053       rs369102407       rs369198420       rs369851208       rs369893168       rs370370574       rs370401948       rs371192803       rs371288618       rs371853220       rs372010849       rs372128112       rs372349714       rs372570611       rs372812523       rs373118114       rs373369517       rs373450899       rs373949248       rs373974298       rs374550929       rs374685958       rs374902462       rs375044079       rs375306799       rs375391319       rs375593312       rs376111618       rs376626260       rs376708009       rs376727697       rs376776890       rs376802160       rs377120794       rs377687329       rs527236103       rs527538362       rs528482125       rs528605519       rs528662813       rs529156413       rs529295739       rs529338772       rs531014611       rs531077633       rs531210663       rs531346738       rs531409081       rs531691276       rs532137084       rs532949412       rs532967085       rs533358632       rs533370883       rs534695614       rs534707151       rs534810430       rs534819675       rs534820968       rs535230697       rs535635302       rs536467893       rs536582170       rs536844415       rs536977497       rs537065273       rs537581749       rs538560123       rs538581410       rs538744995       rs538820015       rs538999065       rs539172762       rs539249995       rs539370960       rs540386305       rs540632143       rs541024414       rs541053156       rs541163949       rs541825239       rs542367012       rs542748394       rs542966841       rs543204560       rs543466160       rs543521798       rs543542992       rs544155208       rs544170990       rs544423048       rs544766619       rs545440059       rs545950016       rs546065873       rs546127355       rs546852513       rs547374351       rs547981493       rs548091071       rs548113513       rs548157527       rs548460589       rs548581449       rs548708237       rs548932276       rs549470128       rs549590160       rs551028346       rs551043575       rs551759609       rs552237368       rs552455660       rs553108022       rs553654969       rs553775083       rs554039303       rs554303709       rs554315811       rs554753426       rs555790621       rs556019320       rs556514951       rs556655422       rs556769049       rs557301477       rs558037874       rs558503555       rs558624347       rs558693495       rs558768385       rs558838311       rs558877754       rs559421777       rs559747229       rs560101491       rs560324786       rs560500100       rs560835715       rs560894093       rs561052129       rs562374398       rs562439338       rs562853201       rs562999077       rs563636567       rs564018441       rs564262280       rs564388429       rs564967700       rs564979898       rs565201858       rs565597965       rs565900188       rs566173741       rs566186118       rs566301956       rs566319717       rs567288669       rs567350735       rs568169643       rs568202024       rs568571580       rs568632402       rs569161209       rs569194631       rs569761830       rs569952875       rs570075375       rs570266760       rs570565774       rs570714427       rs570795323       rs571256673       rs571916150       rs572252938       rs572406990       rs573163746       rs573715035       rs574163826       rs574202023       rs575161157       rs575196456       rs576140640       rs576216267       rs576444344       rs576802125       rs576974880       rs576980794       rs745616372       rs745643650       rs745851408       rs745920387       rs746029882       rs746210043       rs746223530       rs746247806       rs746332355       rs746468201       rs746563423       rs746773592       rs747002188       rs747215789       rs747369599       rs747582133       rs747620121       rs747643955       rs747855401       rs748211662       rs748269752       rs748429090       rs748483575       rs748723598       rs749016955       rs749137786       rs749356883       rs749567084       rs749663446       rs749753555       rs749929388       rs750430777       rs750473517       rs750519691       rs750763646       rs751280060       rs751311620       rs751312906       rs751894032       rs752076372       rs752455127       rs752496804       rs752695098       rs752805805       rs753036982       rs753353276       rs753585848       rs753609310       rs753665727       rs754064314       rs754584217       rs754809715       rs755190538       rs755350955       rs755674549       rs756454203       rs756509737       rs756658659       rs756663175       rs757219458       rs757395830       rs757449302       rs757740913       rs758484916       rs758491851       rs758543619       rs758844049       rs758901694       rs759021503       rs759209103       rs759316820       rs759406692       rs759406789       rs759425622       rs759637818       rs759818475       rs759945007       rs760515764       rs760667657       rs760792843       rs760894205       rs761013258       rs761022507       rs761101263       rs761338278       rs761562089       rs761784827       rs761990733       rs762059468       rs762290223       rs762451457       rs763223221       rs763402049       rs763422574       rs763455152       rs763566456       rs763794994       rs763887860       rs764590515       rs764607760       rs764633076       rs765139791       rs765193154       rs765350593       rs765438313       rs765519035       rs765781218       rs765931092       rs766112074       rs766161322       rs766196737       rs766275471       rs766326902       rs766344345       rs766852589       rs766943400       rs767363145       rs767573351       rs767646428       rs767979610       rs768030547       rs768210562       rs768251138       rs768298431       rs768300463       rs768616082       rs768787274       rs768877243       rs769236224       rs769464362       rs769544430       rs769954281       rs770432635       rs770701400       rs770941561       rs771007146       rs771188148       rs771322615       rs771637224       rs771682972       rs772086479       rs772316842       rs772533932       rs773022490       rs773077062       rs773295145       rs773347364       rs773808406       rs774336493       rs774425557       rs774698907       rs774809893       rs774816413       rs774865494       rs775191474       rs775557680       rs775945120       rs776014770       rs776101913       rs776411064       rs776504351       rs776654836       rs776812466       rs776890381       rs777274073       rs777283396       rs777849735       rs777851867       rs777943803       rs778170529       rs778173978       rs778356027       rs778533886       rs778536018       rs778626065       rs778794165       rs779029199       rs779169631       rs779296525       rs779560689       rs779609930       rs779665096       rs780060597       rs780188527       rs780408367       rs780682812       rs780707497       rs780743370       rs781237162       rs781325869       rs781375897       rs781465927       rs781539793       rs781550757      

RHO基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ATGATGAACAAGCAGTTCCG
59
GTCCTAGGCAGGTCTTAGG
59
TGATGAACAAGCAGTTCCG
59
GTCCTAGGCAGGTCTTAGG
59
GATGAACAAGCAGTTCCGG
59
GTCCTAGGCAGGTCTTAGG
59
      尚未收录相关数据

RHO基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

RHO基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0000139
P08100(UniProtKB)
TAS
GO:0000139
P08100(UniProtKB)
TAS
GO:0000139
P08100(UniProtKB)
TAS
GO:0000139
P08100(UniProtKB)
TAS
GO:0000139
P08100(UniProtKB)
TAS
GO:0000139
P08100(UniProtKB)
TAS
GO:0001523
P08100(UniProtKB)
TAS
GO:0001750
P08100(UniProtKB)
IDA
GO:0001750
P08100(UniProtKB)
IDA
GO:0001917
P08100(UniProtKB)
IDA
GO:0004930
P08100(UniProtKB)
TAS
GO:0005515
P08100(UniProtKB)
IPI
GO:0005515
P08100(UniProtKB)
IPI
GO:0005794
P08100(UniProtKB)
IDA
GO:0005886
P08100(UniProtKB)
IDA
GO:0005887
P08100(UniProtKB)
TAS
GO:0005911
P08100(UniProtKB)
IEA
GO:0006468
P08100(UniProtKB)
IEA
GO:0007186
P08100(UniProtKB)
TAS
GO:0007601
P08100(UniProtKB)
IEA
GO:0007603
P08100(UniProtKB)
TAS
GO:0008020
P08100(UniProtKB)
IBA
GO:0009585
P08100(UniProtKB)
IEA
GO:0016038
P08100(UniProtKB)
ISS
GO:0016038
P08100(UniProtKB)
ISS
GO:0016056
P08100(UniProtKB)
TAS
GO:0016918
P08100(UniProtKB)
IEA
GO:0018298
P08100(UniProtKB)
IEA
GO:0022400
P08100(UniProtKB)
TAS
GO:0030660
P08100(UniProtKB)
TAS
GO:0030660
P08100(UniProtKB)
TAS
GO:0030660
P08100(UniProtKB)
TAS
GO:0030867
P08100(UniProtKB)
IEA
GO:0042622
P08100(UniProtKB)
IDA
GO:0045494
P08100(UniProtKB)
IEA
GO:0046872
P08100(UniProtKB)
IEA
GO:0060041
P08100(UniProtKB)
IEA
GO:0060170
P08100(UniProtKB)
TAS
GO:0060342
P08100(UniProtKB)
IDA
GO:0097381
P08100(UniProtKB)
TAS
GO:0097381
P08100(UniProtKB)
TAS
GO:0097381
P08100(UniProtKB)
TAS
GO:0097381
P08100(UniProtKB)
TAS
GO:0097381
P08100(UniProtKB)
TAS
GO:0097381
P08100(UniProtKB)
TAS
GO:0097381
P08100(UniProtKB)
TAS
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控RHO基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Retinitis Pigmentosa 0.464557081 149 14 BeFree_CLINVAR_CTD_human_GAD_LHGDN_ORPHANET
Night Blindness, Congenital Stationary, Autosomal Dominant 1 0.44 3 3 CLINVAR_CTD_human_MGD_UNIPROT
Retinitis Pigmentosa 4 0.44 17 34 CLINVAR_CTD_human_MGD_UNIPROT
Night blindness, congenital stationary 0.241900093 7 2 BeFree_CTD_human_ORPHANET
Fundus Albipunctatus 0.240542884 2 0 BeFree_CTD_human_ORPHANET
Retinal Degeneration 0.130314791 39 3 BeFree_CTD_human
Retinitis punctata albescens (disorder) 0.122909916 2 1 BeFree_CLINVAR_GAD
Autosomal dominant retinitis pigmentosa 0.037925917 131 13 BeFree_GAD
Retinal Diseases 0.010987159 15 1 BeFree_GAD_LHGDN
Night Blindness 0.006991475 8 2 BeFree_GAD_LHGDN
Neoplasm Metastasis 0.002714419 10 0 BeFree
Autosomal recessive retinitis pigmentosa 0.002442977 9 2 BeFree
Oguchi disease 0.002171535 8 2 BeFree
Photoreceptor degeneration 0.002171535 8 1 BeFree
RETINITIS PIGMENTOSA 1 0.001628651 6 0 BeFree
Degenerative disorder 0.001628651 6 0 BeFree
Diabetic Retinopathy 0.000814326 3 0 BeFree
Neurodegenerative Disorders 0.000814326 3 1 BeFree
Carcinogenesis 0.000814326 3 0 BeFree
Retinal Dystrophies 0.000814326 3 1 BeFree
Rheumatoid Arthritis 0.000542884 2 0 BeFree
melanoma 0.000542884 2 0 BeFree
Nephrotic Syndrome 0.000542884 2 0 BeFree
Retinoblastoma 0.000542884 2 0 BeFree
Photophobia 0.000542884 2 0 BeFree
Tumor Progression 0.000542884 2 0 BeFree
Scotopic sensitivity 0.000542884 2 0 BeFree
Adenocarcinoma 0.000271442 1 0 BeFree
Asthma 0.000271442 1 0 BeFree
Autistic Disorder 0.000271442 1 0 BeFree
Brain Neoplasms 0.000271442 1 0 BeFree
Non-Small Cell Lung Carcinoma 0.000271442 1 0 BeFree
Renal Cell Carcinoma 0.000271442 1 0 BeFree
Choroideremia 0.000271442 1 0 BeFree
Colorectal Carcinoma 0.000271442 1 0 BeFree
Cystic Fibrosis 0.000271442 1 0 BeFree
Chronic Lymphocytic Leukemia 0.000271442 1 0 BeFree
Macular degeneration 0.000271442 1 0 BeFree
Neuroblastoma 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
Refractive Errors 0.000271442 1 2 BeFree
Retinitis 0.000271442 1 0 BeFree
Cerebrovascular accident 0.000271442 1 0 BeFree
Hypertrophy of kidney 0.000271442 1 0 BeFree
Age related macular degeneration 0.000271442 1 0 BeFree
Inflammatory Breast Carcinoma 0.000271442 1 0 BeFree
Liver and Intrahepatic Biliary Tract Carcinoma 0.000271442 1 0 BeFree
Solid tumour 0.000271442 1 0 BeFree
Vitelliform Macular Dystrophy 0.000271442 1 0 BeFree
X-linked retinitis pigmentosa 0.000271442 1 0 BeFree
Malignant neoplasm of liver 0.000271442 1 0 BeFree
Malignant neoplasm of prostate 0.000271442 1 0 BeFree
Prostate carcinoma 0.000271442 1 0 BeFree
Central neuroblastoma 0.000271442 1 0 BeFree
Malignant neoplasm of ovary 0.000271442 1 0 BeFree
Mammary Neoplasms 0.000271442 1 0 BeFree
Cancer Cell Growth 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree
Glioblastoma Multiforme 0.000271442 1 0 BeFree
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 0.000271442 1 0 BeFree
Liver carcinoma 0.000271442 1 0 BeFree
Retina--Diseases 0.000271442 1 0 BeFree
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