FTH1(ferritin, heavy polypeptide 1) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

11q13
基因染色体位置图

基因简述

基因简述

This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  该基因编码铁蛋白重亚单位，在原核生物和真核生物的细胞内主要的铁储存蛋白。它是由重链和轻铁蛋白链的24亚基。变异铁蛋白亚基组成可能会影响铁吸收的速率和不同组织中释放。铁蛋白的一个主要功能是铁在可溶的和无毒的状态的存储。在铁蛋白缺陷与若干神经变性疾病相关联。这个基因具有多个假。几个可变剪接转录物变体已被观察到的，但它们的生物有效性尚未确定。 [由RefSeq的，2008年7月提供]

OMIM数据库中对FTH1基因的介绍     Wikipedia数据库中对FTH1基因的介绍

基因序列

基因序列

FTH1基因的碱基序列：[NCBI]

基因突变

基因突变

FTH1基因的碱基突变：           显示全部snp
rs195155       rs1052603       rs1059856       rs1064740       rs1801327       rs1801621       rs11554842       rs17156609       rs34046408       rs56215258       rs61613252       rs62640569       rs75281081       rs111249745       rs113194529       rs140262296       rs142482048       rs143838307       rs146700893       rs148714447       rs151320251       rs181016777       rs181156664       rs187560307       rs189452274       rs189937363       rs200266717       rs201586629       rs202009890       rs367593479       rs369207712       rs369985911       rs370449319       rs370733188       rs370763150       rs371388537       rs371949168      
rs373899527       rs374722361       rs374812527       rs375289480       rs375508666       rs377371056       rs377707464       rs527436384       rs534854547       rs542292756       rs549950643       rs551153413       rs552466453       rs556116201       rs558776825       rs562666877       rs565070598       rs565138844       rs565942468       rs566003862       rs567717860       rs745605499       rs746655230       rs747099089       rs747203605       rs748186888       rs748505594       rs750011059       rs750843363       rs751838445       rs753284051       rs753621558       rs754343811       rs754761602       rs755490259       rs755508306       rs755785837       rs755879430       rs756494937       rs756847190       rs756900543       rs757459959       rs758109637       rs759829740       rs759902073       rs760346820       rs760826866       rs760876662       rs760927574       rs762901207       rs763591193       rs764201796       rs765331141       rs765723689       rs766747484       rs766832179       rs767112958       rs767678543       rs767733527       rs768532658       rs768583228       rs769182401       rs769738793       rs770767972       rs770879492       rs771129386       rs771570160       rs771644153       rs772060059       rs772109161       rs772282996       rs774342743       rs774482982       rs775188176       rs775515361       rs776566073       rs776738846       rs776989878       rs777327148       rs778011064       rs779305383       rs780121825       rs780554376       rs195154       rs2019413       rs2073588       rs4963438       rs11230841       rs11230842       rs11271453       rs11554869       rs11554872       rs11554886       rs12270214       rs34316319       rs34621192       rs41453449       rs57975282       rs60471683       rs60517521       rs71477602       rs73493231       rs76059597       rs76178964       rs77202794       rs77709427       rs79502317       rs112106635       rs112771252       rs114039236       rs114778979       rs114865849       rs115280577       rs115415197       rs138403138       rs138893669       rs143934186       rs144920458       rs146414690       rs146971597       rs150299199       rs181553435       rs182219101       rs183002308       rs183128980       rs185495199       rs185835490       rs186432937       rs186448909       rs191473962       rs191702409       rs199565739       rs199912260       rs200270983       rs201120647       rs201178063       rs368627145       rs368857190       rs369867836       rs370105090       rs371283538       rs371448455       rs373126300       rs373393355       rs374301256       rs374746157       rs375217149       rs376549851       rs377397136       rs398016274       rs528164427       rs528773146       rs529102670       rs530385784       rs531098214       rs531158108       rs531837183       rs532238231       rs532896841       rs533522150       rs533585798       rs534227628       rs534286631       rs535212301       rs536879280       rs536944748       rs537209118       rs537831712       rs539713245       rs540171162       rs541569241       rs542244972       rs543178810       rs543520900       rs544929103       rs545832467       rs545895755       rs546464863       rs546822200       rs547859567       rs548123284       rs548547478       rs548804291       rs548873461       rs549143720       rs549229008       rs549920653       rs550139677       rs550477487       rs551851462       rs552130899       rs552315310       rs553010722       rs553455761       rs553989935       rs554524983       rs554869393       rs555071913       rs555401255       rs555788021       rs556790843       rs558172653       rs558574166       rs558728583       rs559319937       rs559432387       rs560365083       rs560516823       rs561131409       rs561412634       rs561531161       rs563738314       rs564075921       rs564670671       rs564732275       rs565609341       rs565677183       rs566554505       rs568384182       rs568643410       rs569741966       rs569804748       rs570322118       rs570386508       rs572295274       rs572350864       rs573237623       rs574130894       rs574498507       rs574587457       rs576056583       rs576911226       rs578245779       rs745344806       rs745653116       rs745801010       rs745957970       rs746025468       rs746051501       rs746763203       rs747239060       rs747489814       rs747618890       rs747825826       rs748522140       rs748554148       rs748747023       rs748800078       rs749346675       rs749631169       rs749673629       rs749884272       rs750344819       rs750410698       rs750898501       rs751217371       rs751238079       rs751425119       rs751862506       rs751983239       rs752433391       rs752558122       rs752935701       rs753401296       rs753914758       rs754038501       rs754091676       rs754545791       rs754709149       rs755308814       rs756338146       rs756637953       rs757136218       rs757310359       rs757639262       rs757690602       rs757879716       rs758012761       rs758213920       rs758594792       rs758825329       rs759109589       rs759443253       rs759715857       rs760127724       rs760970907       rs761179544       rs761682163       rs762062051       rs762576690       rs762631821       rs762770399       rs762952280       rs763229761       rs763318260       rs763850597       rs764249736       rs764824032       rs764878960       rs765255565       rs765334880       rs765340386       rs766424142       rs766553821       rs766810447       rs767306127       rs767844624       rs768136029       rs768359831       rs769113703       rs769682212       rs770111345       rs770210526       rs770947617       rs771481657       rs771879508       rs772287029       rs772405543       rs772706632       rs773074816       rs773201278       rs773950332       rs774072766       rs774463289       rs774906313       rs775027611       rs775152275       rs775487213       rs775493889       rs775570370       rs776621212       rs776634911       rs776743495       rs776746010       rs777469755       rs777594256       rs777703333       rs778035914       rs778326000       rs778369396       rs778481941       rs778670802       rs779531508       rs780322158       rs781115599       rs781125529       rs781369198       rs781672849      

基因表达

基因表达

FTH1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CTACCACCAGGACTCAGAG
59
AGTAGTAAGACATGGACAGGT
58
CTTCCTTCAGGATATCAAGAAACC
59
TTCCAAATGTAATGCACACTCC
60
AACTACCACCAGGACTCAG
58
CTGTGACGATCATGGACAG
58
AGTCTTACTACTTTGACCGC
57
AGTCTGGTTTCTTGATATCCTG
58
GATATCAAGAAACCAGACTGTG
57
TTCCAGTAGTGACTGATTCAC
58
GTTTACCTGTCCATGGTCCT
60
TGTGGGACTTCTTCTGTCC
59
TACCTGTCCATGCCAACAG
60
CACATACAAGGTCCTGCCT
59
CTTCCTTCAGGATATCAAGAAACC
59
TTCCAAATGTAATGCACACTCC
60
CTGTCCATGTCTTACTACTTTGAC
59
CCTCTCCTCATGAGATTGGT
59
TACCTGTCCATGCCAACAG
60
ACATACAAGGTCCTGCCTG
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

FTH1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

FTH1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0005623
E9PK45(UniProtKB)
IEA
GO:0006826
E9PK45(UniProtKB)
IEA
GO:0006879
E9PK45(UniProtKB)
IEA
GO:0008199
E9PK45(UniProtKB)
IEA
GO:0005623
E9PKM5(UniProtKB)
IEA
GO:0006826
E9PKM5(UniProtKB)
IEA
GO:0006879
E9PKM5(UniProtKB)
IEA
GO:0008199
E9PKM5(UniProtKB)
IEA
GO:0005623
E9PKY7(UniProtKB)
IEA
GO:0006826
E9PKY7(UniProtKB)
IEA
GO:0006879
E9PKY7(UniProtKB)
IEA
GO:0008199
E9PKY7(UniProtKB)
IEA
GO:0005623
E9PPQ4(UniProtKB)
IEA
GO:0006826
E9PPQ4(UniProtKB)
IEA
GO:0006879
E9PPQ4(UniProtKB)
IEA
GO:0008199
E9PPQ4(UniProtKB)
IEA
GO:0005623
E9PQR3(UniProtKB)
IEA
GO:0006826
E9PQR3(UniProtKB)
IEA
GO:0006879
E9PQR3(UniProtKB)
IEA
GO:0008199
E9PQR3(UniProtKB)
IEA
GO:0016021
E9PQR3(UniProtKB)
IEA
GO:0005623
E9PRK8(UniProtKB)
IEA
GO:0006826
E9PRK8(UniProtKB)
IEA
GO:0006879
E9PRK8(UniProtKB)
IEA
GO:0008199
E9PRK8(UniProtKB)
IEA
GO:0005623
G3V192(UniProtKB)
IEA
GO:0006826
G3V192(UniProtKB)
IEA
GO:0006879
G3V192(UniProtKB)
IEA
GO:0008199
G3V192(UniProtKB)
IEA
GO:0005623
G3V1D1(UniProtKB)
IEA
GO:0006826
G3V1D1(UniProtKB)
IEA
GO:0006879
G3V1D1(UniProtKB)
IEA
GO:0008199
G3V1D1(UniProtKB)
IEA
GO:0004322
P02794(UniProtKB)
IEA
GO:0005506
P02794(UniProtKB)
TAS
GO:0005515
P02794(UniProtKB)
IPI
GO:0005515
P02794(UniProtKB)
IPI
GO:0005515
P02794(UniProtKB)
IPI
GO:0005515
P02794(UniProtKB)
IPI
GO:0005515
P02794(UniProtKB)
IPI
GO:0005515
P02794(UniProtKB)
IPI
GO:0005515
P02794(UniProtKB)
IPI
GO:0005515
P02794(UniProtKB)
IPI
GO:0005515
P02794(UniProtKB)
IPI
GO:0005515
P02794(UniProtKB)
IPI
GO:0005634
P02794(UniProtKB)
IDA
GO:0005829
P02794(UniProtKB)
TAS
GO:0005829
P02794(UniProtKB)
TAS
GO:0006826
P02794(UniProtKB)
IEA
GO:0006879
P02794(UniProtKB)
TAS
GO:0006880
P02794(UniProtKB)
IDA
GO:0006955
P02794(UniProtKB)
ISS
GO:0008043
P02794(UniProtKB)
TAS
GO:0008199
P02794(UniProtKB)
IEA
GO:0008285
P02794(UniProtKB)
ISS
GO:0048147
P02794(UniProtKB)
IDA
GO:0055114
P02794(UniProtKB)
IEA
GO:0070062
P02794(UniProtKB)
IDA
GO:0070062
P02794(UniProtKB)
IDA
GO:0070062
P02794(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控FTH1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Iron Overload 0.123267234 4 0 BeFree_CTD_human_LHGDN
Depressive disorder 0.12 1 0 CTD_human
Contact Dermatitis 0.12 1 0 CTD_human
Glioma 0.12 1 0 CTD_human
Keloid 0.12 1 0 CTD_human
Neoplasm Invasiveness 0.12 1 0 CTD_human
Precancerous Conditions 0.12 1 0 CTD_human
Neurodegenerative Disorders 0.12 1 0 CTD_human
Iron Overload, Autosomal Dominant 0.12 0 0 ORPHANET
Liver carcinoma 0.080271442 2 0 BeFree_RGD
Heart failure 0.08 1 0 RGD
Parkinson Disease 0.004734064 2 0 GAD
Hemochromatosis 0.003267234 3 0 BeFree_LHGDN
Infection 0.00272435 1 0 LHGDN
Colorectal Carcinoma 0.000542884 2 0 BeFree
Colorectal Cancer 0.000542884 2 0 BeFree
Friedreich Ataxia 0.000271442 1 0 BeFree
Hepatitis C 0.000271442 1 0 BeFree
Hypercholesterolemia, Familial 0.000271442 1 0 BeFree
Lymphoma 0.000271442 1 0 BeFree
Serum Sickness 0.000271442 1 0 BeFree
Ankylosing spondylitis 0.000271442 1 0 BeFree
Virus Diseases 0.000271442 1 0 BeFree
Glucocorticoid deficiency with achalasia 0.000271442 1 0 BeFree
Adenocarcinoma Of Esophagus 0.000271442 1 0 BeFree
Solid tumour 0.000271442 1 0 BeFree
Secondary malignant neoplasm of lymph node 0.000271442 1 0 BeFree
Spondylarthropathies 0.000271442 1 0 BeFree
Allergic sensitization 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

基因评论

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