Combined effects of ZnO and TiO2 nanoparticles on functional gene expression of Nitrosomonas europaea-基因实验库-基因云馆

状态

生成时间 2015-06-23 最后修正 2015-06-27

物种

Nitrosomonas europaea ATCC 19718

中文描述

为了进一步探讨和区分单个纳米颗粒（NP）和NP混合物在基因水平上的亚硝化单胞菌（N. europaea，ATCC 19718）的生物毒性机制，基因组测序模型氨氧化细菌（AOB）通常在活性污泥生物废水处理厂，在单和双组分NP系统中的N. europaea的生理，代谢和AMO酶活性的剂量依赖性变化之后，用高通量微阵列技术分析诱导的全基因组表达。 NP应力诱导的基因表达在6ppm暴露于10ppm纳米ZnO，50纳米TiO 2及其混合物之后测量。对于每个实验进行三次独立实验。

英文描述

To further explore and differentiate the biotoxicity mechanisms of individual nanoparticles (NPs) and NP mixture on Nitrosomonas europaea (N. europaea, ATCC 19718) at genetic level, a genome-sequenced model ammonia oxidizing bacterium (AOB) commonly detected in the activated sludge of biological wastewater treatment plants, the induced whole-genome expressions were analyzed with the high throughput Microarray technique, after the dose-dependent changes of N. europaea’s physiological, metabolic and AMO enzyme activities in single and dual component NP systems was evaluated. NP stress induced gene expressions were measured after 6hr exposure to 10 ppm nano-ZnO, 50 nano-TiO2 and their mixture.Three independent experiments were performed for each experiment.

文献来源

实验类型

transcription profiling by array

实验样本量

12

样本类型

[{"id":"29547"},{"accession":"A-GEOD-18989"},{"name":"Nitrosomonas europaea Kangchen Custom Expression Microarray"},{"count":"12"}]

数据文件链接

[{"raw_name":"E-GEOD-70121.raw.1.zip","raw_count":"true","raw_celcount":"0"},{"raw":""},{"fgem_name":"E-GEOD-70121.processed.1.zip","fgem_available":"true"},{"fgem":""},{"idf_name":"E-GEOD-70121.idf.txt"},{"idf":""},{"sdrf_name":"E-GEOD-70121.sdrf.txt"},{"sdrf":""}]

联系人

[{"contact":"Ran Yu"},{"role":""},{"email":""}]

数据库编号

E-GEOD-70121

原数据编号

GSE70121

分析链接

进入分析平台分析这组数据

Combined effects of ZnO and TiO2 nanoparticles on functional gene expression of Nitrosomonas europaea

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